SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6cgu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DDY_A_RBFA187_1 (LUMAZINE PROTEIN)	6cgu	CADHERIN-6 (Mus musculus)	5 / 12	THR A 198 ILE A 148 GLN A 150 ASN A 202 ILE A 203	THR A 198 ( 0.8A) ILE A 148 ( 0.6A) GLN A 150 ( 0.6A) ASN A 202 ( 0.6A) ILE A 203 ( 0.7A)	1.10A	3ddyA-6cguA: undetectable	3ddyA-6cguA: 21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KO0_A_TFPA201_1 (PROTEIN S100-A4)	6cgu	CADHERIN-6 (Mus musculus)	5 / 9	ILE A 96 PHE A 7 PHE A 92 PHE A 48 GLY A 43	ILE A 96 ( 0.7A) PHE A 7 ( 1.3A) PHE A 92 ( 1.3A) PHE A 48 ( 1.3A) GLY A 43 ( 0.0A)	1.42A	3ko0A-6cguA: undetectable 3ko0C-6cguA: undetectable	3ko0A-6cguA: 18.00 3ko0C-6cguA: 18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KO0_I_TFPI201_1 (PROTEIN S100-A4)	6cgu	CADHERIN-6 (Mus musculus)	5 / 9	PHE A 48 GLY A 43 ILE A 96 PHE A 7 PHE A 92	PHE A 48 ( 1.3A) GLY A 43 ( 0.0A) ILE A 96 ( 0.7A) PHE A 7 ( 1.3A) PHE A 92 ( 1.3A)	1.39A	3ko0H-6cguA: undetectable 3ko0I-6cguA: undetectable	3ko0H-6cguA: 18.00 3ko0I-6cguA: 18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KO0_R_TFPR201_1 (PROTEIN S100-A4)	6cgu	CADHERIN-6 (Mus musculus)	5 / 10	ILE A 96 PHE A 7 PHE A 92 PHE A 48 GLY A 43	ILE A 96 ( 0.7A) PHE A 7 ( 1.3A) PHE A 92 ( 1.3A) PHE A 48 ( 1.3A) GLY A 43 ( 0.0A)	1.40A	3ko0R-6cguA: undetectable 3ko0T-6cguA: undetectable	3ko0R-6cguA: 18.00 3ko0T-6cguA: 18.00

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3DDY_A_RBFA187_1","LUMAZINE PROTEIN","6cgu","CADHERIN-6","Mus musculus",5,"THR A 198;ILE A 148;GLN A 150;ASN A 202;ILE A 203","THR A 198 ( 0.8A);ILE A 148 ( 0.6A);GLN A 150 ( 0.6A);ASN A 202 ( 0.6A);ILE A 203 ( 0.7A)","1.10A","3ddyA-6cguA:undetectable","3ddyA-6cguA:21.05"],["3KO0_A_TFPA201_1","PROTEIN S100-A4;PROTEIN S100-A4","6cgu","CADHERIN-6","Mus musculus",5,"ILE A  96;PHE A   7;PHE A  92;PHE A  48;GLY A  43","ILE A  96 ( 0.7A);PHE A   7 ( 1.3A);PHE A  92 ( 1.3A);PHE A  48 ( 1.3A);GLY A  43 ( 0.0A)","1.42A","3ko0A-6cguA:undetectable;3ko0C-6cguA:undetectable","3ko0A-6cguA:18.00;3ko0C-6cguA:18.00"],["3KO0_I_TFPI201_1","PROTEIN S100-A4;PROTEIN S100-A4","6cgu","CADHERIN-6","Mus musculus",5,"PHE A  48;GLY A  43;ILE A  96;PHE A   7;PHE A  92","PHE A  48 ( 1.3A);GLY A  43 ( 0.0A);ILE A  96 ( 0.7A);PHE A   7 ( 1.3A);PHE A  92 ( 1.3A)","1.39A","3ko0H-6cguA:undetectable;3ko0I-6cguA:undetectable","3ko0H-6cguA:18.00;3ko0I-6cguA:18.00"],["3KO0_R_TFPR201_1","PROTEIN S100-A4;PROTEIN S100-A4","6cgu","CADHERIN-6","Mus musculus",5,"ILE A  96;PHE A   7;PHE A  92;PHE A  48;GLY A  43","ILE A  96 ( 0.7A);PHE A   7 ( 1.3A);PHE A  92 ( 1.3A);PHE A  48 ( 1.3A);GLY A  43 ( 0.0A)","1.40A","3ko0R-6cguA:undetectable;3ko0T-6cguA:undetectable","3ko0R-6cguA:18.00;3ko0T-6cguA:18.00"]]