SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6ch3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSE_B_EAAB224_1
(GLUTATHIONE
TRANSFERASE)		 6ch3 FLAGELLAR
BIOSYNTHESIS PROTEIN
FLHA
(Salmonella
enterica) 		5 / 12 ARG A 555
LEU A 558
LEU A 561
VAL A 578
LEU A 582
 None
 0.98A 1gseB-6ch3A:
1.8		 1gseB-6ch3A:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y7I_A_SALA501_1
(SALICYLIC
ACID-BINDING PROTEIN
2)		 6ch3 FLAGELLAR SECRETION
CHAPERONE
FLIS,FLAGELLIN
(Salmonella
enterica) 		5 / 9 GLY B  55
ALA B  57
SER B  59
LEU B  58
LEU B  39
 None
 1.35A 1y7iA-6ch3B:
undetectable		 1y7iA-6ch3B:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_A_P1BA1478_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 6ch3 FLAGELLAR SECRETION
CHAPERONE
FLIS,FLAGELLIN
(Salmonella
enterica) 		4 / 7 LEU B  96
ILE B  65
ALA B 121
ILE B 174
 None
 0.81A 2xkwA-6ch3B:
undetectable		 2xkwA-6ch3B:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE510_2
(PHOSPHOLIPASE A2)		 6ch3 FLAGELLAR
BIOSYNTHESIS PROTEIN
FLHA
(Salmonella
enterica) 		4 / 6 LYS A 392
GLN A 396
GLY A 399
LEU A 545
 None
 1.02A 3bjwE-6ch3A:
undetectable		 3bjwE-6ch3A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BU1_A_HSMA301_1
(LIPOCALIN)		 6ch3 FLAGELLAR
BIOSYNTHESIS PROTEIN
FLHA
FLAGELLAR SECRETION
CHAPERONE
FLIS,FLAGELLIN
(Salmonella
enterica) 		4 / 7 VAL A 487
TYR B  10
ILE A 440
TRP A 465
 None
 1.12A 3bu1A-6ch3A:
undetectable		 3bu1A-6ch3A:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_B_CELB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 6ch3 FLAGELLAR
BIOSYNTHESIS PROTEIN
FLHA
(Salmonella
enterica) 		5 / 12 HIS A 491
VAL A 367
LEU A 371
ILE A 420
GLY A 364
 None
 1.14A 3kk6B-6ch3A:
undetectable		 3kk6B-6ch3A:
10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZT_A_SAMA1472_1
(METHYLTRANSFERASE
WBDD)		 6ch3 FLAGELLAR
BIOSYNTHESIS PROTEIN
FLHA
FLAGELLAR SECRETION
CHAPERONE
FLIS,FLAGELLIN
(Salmonella
enterica;
Salmonella
enterica) 		3 / 3 GLN B  12
ASP A 397
GLN A 396
 None
 0.78A 4aztA-6ch3B:
undetectable		 4aztA-6ch3B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G24_A_ACAA1004_1
(PENTATRICOPEPTIDE
REPEAT-CONTAINING
PROTEIN AT2G32230,
MITOCHONDRIAL)		 6ch3 FLAGELLAR SECRETION
CHAPERONE
FLIS,FLAGELLIN
(Salmonella
enterica) 		4 / 6 ALA B  35
ASN B  36
LEU B  39
VAL B  40
 None
 0.79A 4g24A-6ch3B:
2.6		 4g24A-6ch3B:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_C_RTLC201_0
(RETINOL-BINDING
PROTEIN 2)		 6ch3 FLAGELLAR
BIOSYNTHESIS PROTEIN
FLHA
FLAGELLAR SECRETION
CHAPERONE
FLIS,FLAGELLIN
(Salmonella
enterica;
Salmonella
enterica) 		5 / 12 ILE B  64
ALA B  38
GLN A 475
THR A 486
LEU B 197
 None
 1.50A 4qztC-6ch3B:
undetectable		 4qztC-6ch3B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNW_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 6ch3 FLAGELLAR
BIOSYNTHESIS PROTEIN
FLHA
(Salmonella
enterica) 		5 / 12 HIS A 538
LEU A 541
PHE A 400
LEU A 545
PRO A 403
 None
 1.20A 5hnwB-6ch3A:
undetectable		 5hnwB-6ch3A:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNX_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 6ch3 FLAGELLAR
BIOSYNTHESIS PROTEIN
FLHA
(Salmonella
enterica) 		5 / 12 HIS A 538
LEU A 541
PHE A 400
LEU A 545
PRO A 403
 None
 1.20A 5hnxB-6ch3A:
undetectable		 5hnxB-6ch3A:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNY_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 6ch3 FLAGELLAR
BIOSYNTHESIS PROTEIN
FLHA
(Salmonella
enterica) 		5 / 12 HIS A 538
LEU A 541
PHE A 400
LEU A 545
PRO A 403
 None
 1.19A 5hnyB-6ch3A:
undetectable		 5hnyB-6ch3A:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGI_A_ZITA402_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 6ch3 FLAGELLAR
BIOSYNTHESIS PROTEIN
FLHA
(Salmonella
enterica) 		5 / 12 ILE A 420
VAL A 367
MET A 374
VAL A 375
GLY A 435
 None
 1.18A 5igiA-6ch3A:
undetectable		 5igiA-6ch3A:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGJ_A_CTYA402_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 6ch3 FLAGELLAR
BIOSYNTHESIS PROTEIN
FLHA
(Salmonella
enterica) 		6 / 12 MET A 365
ILE A 420
VAL A 367
MET A 374
VAL A 375
GLY A 435
 None
 1.43A 5igjA-6ch3A:
undetectable		 5igjA-6ch3A:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGV_A_ZITA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 6ch3 FLAGELLAR
BIOSYNTHESIS PROTEIN
FLHA
(Salmonella
enterica) 		5 / 12 ILE A 420
TYR A 418
HIS A 491
ALA A 432
ILE A 390
 None
 1.26A 5igvA-6ch3A:
undetectable		 5igvA-6ch3A:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_A_TLFA601_0
(PROSTAGLANDIN G/H
SYNTHASE 2)		 6ch3 FLAGELLAR SECRETION
CHAPERONE
FLIS,FLAGELLIN
(Salmonella
enterica) 		5 / 12 VAL B 111
LEU B 197
GLY B  34
ALA B  35
LEU B  39
 None
 1.10A 5iktA-6ch3B:
undetectable		 5iktA-6ch3B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_B_TLFB601_0
(PROSTAGLANDIN G/H
SYNTHASE 2)		 6ch3 FLAGELLAR SECRETION
CHAPERONE
FLIS,FLAGELLIN
(Salmonella
enterica) 		5 / 12 VAL B 111
LEU B 197
GLY B  34
ALA B  35
LEU B  39
 None
 1.09A 5iktB-6ch3B:
1.2		 5iktB-6ch3B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 6ch3 FLAGELLAR
BIOSYNTHESIS PROTEIN
FLHA
(Salmonella
enterica) 		4 / 4 LEU A 503
ARG A 391
ILE A 496
PHE A 394
 None
 1.36A 5kirB-6ch3A:
undetectable		 5kirB-6ch3A:
9.71