SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6chs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQU_A_EQIA329_0
(PROTEIN (ESTRADIOL
17
BETA-DEHYDROGENASE
1))		 6chs PUTATIVE CELL
DIVISION CONTROL
PROTEIN
(Chaetomium
thermophilum) 		5 / 10 SER H 764
VAL H 765
LEU H 664
PRO H 537
GLU H 774
 None
None
None
AGS  H 902 (-4.8A)
None
 1.33A 1equA-6chsH:
undetectable		 1equA-6chsH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P9G_A_ACTA42_0
(EAFP 2)		 6chs NPL4
(Chaetomium
thermophilum) 		3 / 3 CYH A 171
ARG A 154
CYH A 168
 ZN  A 701 (-2.3A)
None
ZN  A 701 (-2.3A)
 1.13A 1p9gA-6chsA:
undetectable		 1p9gA-6chsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_B_DAHB208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 6chs NPL4
(Chaetomium
thermophilum) 		5 / 12 LEU A 564
GLU A 561
ARG A 567
TYR A 336
ILE A 551
 None
 1.18A 1rnrB-6chsA:
undetectable		 1rnrB-6chsA:
11.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_B_SAMB302_1
(HEMK PROTEIN)		 6chs PUTATIVE CELL
DIVISION CONTROL
PROTEIN
(Chaetomium
thermophilum) 		3 / 3 ASP H 626
PHE H 580
ASN H 619
 None
 0.78A 1sg9B-6chsH:
3.4		 1sg9B-6chsH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_A_SAMA4000_0
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 6chs PUTATIVE CELL
DIVISION CONTROL
PROTEIN
(Chaetomium
thermophilum) 		5 / 12 ILE H 637
GLY H 638
LEU H 656
VAL H 617
ILE H 576
 None
 1.05A 1zq9A-6chsH:
2.2		 1zq9A-6chsH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTJ_A_THRA401_0
(ASPARTOKINASE)		 6chs PUTATIVE CELL
DIVISION CONTROL
PROTEIN
(Chaetomium
thermophilum) 		4 / 8 GLY H 218
GLU H 277
ALA H 273
ILE H 222
 None
 0.84A 2dtjA-6chsH:
undetectable
2dtjB-6chsH:
undetectable		 2dtjA-6chsH:
undetectable
2dtjB-6chsH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E7F_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 6chs PUTATIVE CELL
DIVISION CONTROL
PROTEIN
(Chaetomium
thermophilum) 		5 / 12 MET H 404
ILE H 222
LEU H 269
GLY H 424
ILE H 396
 None
None
AGS  H 901 (-4.4A)
AGS  H 901 (-3.5A)
AGS  H 901 ( 4.2A)
 1.26A 2e7fA-6chsH:
2.3		 2e7fA-6chsH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E7F_B_C2FB4000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 6chs PUTATIVE CELL
DIVISION CONTROL
PROTEIN
(Chaetomium
thermophilum) 		5 / 12 MET H 404
ILE H 222
LEU H 269
GLY H 424
ILE H 396
 None
None
AGS  H 901 (-4.4A)
AGS  H 901 (-3.5A)
AGS  H 901 ( 4.2A)
 1.20A 2e7fB-6chsH:
2.3		 2e7fB-6chsH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KI5_A_AC2A1_1
(PROTEIN (THYMIDINE
KINASE))		 6chs NPL4
(Chaetomium
thermophilum) 		5 / 12 HIS A 546
GLU A 520
GLN A 553
ARG A 515
GLU A 309
 None
 1.33A 2ki5A-6chsA:
undetectable		 2ki5A-6chsA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OGY_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 6chs PUTATIVE CELL
DIVISION CONTROL
PROTEIN
(Chaetomium
thermophilum) 		5 / 12 MET H 404
ILE H 222
LEU H 269
GLY H 424
ILE H 396
 None
None
AGS  H 901 (-4.4A)
AGS  H 901 (-3.5A)
AGS  H 901 ( 4.2A)
 1.26A 2ogyA-6chsH:
2.2		 2ogyA-6chsH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OGY_B_C2FB4000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 6chs PUTATIVE CELL
DIVISION CONTROL
PROTEIN
(Chaetomium
thermophilum) 		5 / 12 MET H 404
ILE H 222
LEU H 269
GLY H 424
ILE H 396
 None
None
AGS  H 901 (-4.4A)
AGS  H 901 (-3.5A)
AGS  H 901 ( 4.2A)
 1.23A 2ogyB-6chsH:
2.4		 2ogyB-6chsH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_C_SAMC300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 6chs PUTATIVE CELL
DIVISION CONTROL
PROTEIN
(Chaetomium
thermophilum) 		4 / 4 SER H 672
GLY H 498
HIS H 697
ASP H 767
 None
 1.14A 2oxtC-6chsH:
undetectable		 2oxtC-6chsH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_A_SAMA400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 6chs PUTATIVE CELL
DIVISION CONTROL
PROTEIN
(Chaetomium
thermophilum) 		3 / 3 ASN H 619
ARG H 616
ASP H 609
 None
 0.90A 2qe6A-6chsH:
undetectable		 2qe6A-6chsH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_B_SAMB400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 6chs PUTATIVE CELL
DIVISION CONTROL
PROTEIN
(Chaetomium
thermophilum) 		3 / 3 ASN H 619
ARG H 616
ASP H 609
 None
 0.89A 2qe6B-6chsH:
undetectable		 2qe6B-6chsH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDV_E_SAME1287_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 6chs NPL4
(Chaetomium
thermophilum) 		5 / 12 GLY A 408
GLY A 412
ILE A 414
CYH A 361
ASP A 351
 None
 1.10A 2vdvE-6chsA:
undetectable		 2vdvE-6chsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WX2_B_TPFB1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 6chs PUTATIVE CELL
DIVISION CONTROL
PROTEIN
(Chaetomium
thermophilum) 		4 / 8 ALA H 271
ALA H 275
THR H 278
LEU H 240
 None
 0.91A 2wx2B-6chsH:
undetectable		 2wx2B-6chsH:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_C_ACHC1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 6chs NPL4
(Chaetomium
thermophilum) 		4 / 8 VAL A 330
TYR A 336
CYH A 566
CYH A 337
 None
 1.27A 2xz5A-6chsA:
undetectable
2xz5C-6chsA:
undetectable		 2xz5A-6chsA:
undetectable
2xz5C-6chsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_D_ACHD1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 6chs NPL4
(Chaetomium
thermophilum) 		4 / 8 VAL A 330
TYR A 336
CYH A 566
CYH A 337
 None
 1.26A 2xz5C-6chsA:
undetectable
2xz5D-6chsA:
undetectable		 2xz5C-6chsA:
undetectable
2xz5D-6chsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_A_DGXA1_1
(NUCLEAR RECEPTOR
ROR-GAMMA)		 6chs PUTATIVE CELL
DIVISION CONTROL
PROTEIN
(Chaetomium
thermophilum) 		5 / 12 LEU H 258
ALA H 326
ALA H 361
VAL H 359
PHE H 306
 None
 1.25A 3b0wA-6chsH:
undetectable		 3b0wA-6chsH:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_B_DGXB1_1
(NUCLEAR RECEPTOR
ROR-GAMMA)		 6chs PUTATIVE CELL
DIVISION CONTROL
PROTEIN
(Chaetomium
thermophilum) 		5 / 12 LEU H 258
ALA H 326
ALA H 361
VAL H 359
PHE H 306
 None
 1.24A 3b0wB-6chsH:
undetectable		 3b0wB-6chsH:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L4D_D_TPFD490_1
(STEROL 14-ALPHA
DEMETHYLASE)		 6chs PUTATIVE CELL
DIVISION CONTROL
PROTEIN
(Chaetomium
thermophilum) 		4 / 8 ALA H 271
ALA H 275
THR H 278
LEU H 240
 None
 1.01A 3l4dD-6chsH:
undetectable		 3l4dD-6chsH:
10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LPS_A_NOVA901_1
(TOPOISOMERASE IV
SUBUNIT B)		 6chs PUTATIVE CELL
DIVISION CONTROL
PROTEIN
(Chaetomium
thermophilum) 		5 / 12 ASN H 367
SER H 368
ASP H 323
PRO H 262
THR H 363
 None
 1.24A 3lpsA-6chsH:
undetectable		 3lpsA-6chsH:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD507_1
(HEMOLYTIC LECTIN
CEL-III)		 6chs NPL4
(Chaetomium
thermophilum) 		4 / 5 ASP A 356
GLU A 413
GLY A 412
ASP A 351
 None
 1.20A 3w9tD-6chsA:
undetectable		 3w9tD-6chsA:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFG_C_QMRC1214_1
(CAPITELLA TELETA
ACHBP)		 6chs NPL4
(Chaetomium
thermophilum) 		4 / 8 VAL A 330
TYR A 336
CYH A 566
CYH A 337
 None
 0.94A 4afgD-6chsA:
undetectable
4afgE-6chsA:
undetectable		 4afgD-6chsA:
16.13
4afgE-6chsA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AGA_A_ACTA1131_0
(LYSOZYME C)		 6chs PUTATIVE CELL
DIVISION CONTROL
PROTEIN
(Chaetomium
thermophilum) 		3 / 3 ASN H 367
ASP H 578
ASN H 575
 None
 0.74A 4agaA-6chsH:
undetectable		 4agaA-6chsH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQT_C_C5EC301_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 6chs NPL4
(Chaetomium
thermophilum) 		4 / 8 VAL A 330
TYR A 336
CYH A 566
CYH A 337
 None
 1.12A 4bqtC-6chsA:
undetectable
4bqtD-6chsA:
undetectable		 4bqtC-6chsA:
undetectable
4bqtD-6chsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0V_D_MIXD101_1
(DNA TOPOISOMERASE
2-BETA)		 6chs PUTATIVE CELL
DIVISION CONTROL
PROTEIN
(Chaetomium
thermophilum) 		4 / 6 GLY H 261
ASN H 367
GLN H 231
MET H 235
 None
 1.31A 4g0vB-6chsH:
undetectable		 4g0vB-6chsH:
8.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0V_D_MIXD101_1
(DNA TOPOISOMERASE
2-BETA)		 6chs PUTATIVE CELL
DIVISION CONTROL
PROTEIN
(Chaetomium
thermophilum) 		4 / 6 GLY H 261
ASN H 575
GLN H 231
MET H 235
 None
 1.18A 4g0vB-6chsH:
undetectable		 4g0vB-6chsH:
8.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I13_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 6chs PUTATIVE CELL
DIVISION CONTROL
PROTEIN
(Chaetomium
thermophilum) 		3 / 3 ASP H 320
ARG H 365
THR H 268
 MG  H 903 (-3.1A)
None
MG  H 903 ( 3.5A)
 0.89A 4i13A-6chsH:
undetectable		 4i13A-6chsH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IOM_A_FOLA608_0
(FORMATE--TETRAHYDROF
OLATE LIGASE)		 6chs PUTATIVE CELL
DIVISION CONTROL
PROTEIN
(Chaetomium
thermophilum) 		4 / 7 ALA H 416
PRO H 390
LEU H 427
LEU H 397
 None
 1.02A 4iomA-6chsH:
2.2		 4iomA-6chsH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 6chs NPL4
(Chaetomium
thermophilum) 		4 / 7 GLU A 516
GLU A 520
GLU A 513
GLU A 309
 None
 1.29A 4mi4A-6chsA:
undetectable
4mi4C-6chsA:
undetectable		 4mi4A-6chsA:
18.32
4mi4C-6chsA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P3R_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 6chs PUTATIVE CELL
DIVISION CONTROL
PROTEIN
(Chaetomium
thermophilum) 		3 / 3 ASP H 320
ARG H 365
THR H 268
 MG  H 903 (-3.1A)
None
MG  H 903 ( 3.5A)
 0.87A 4p3rA-6chsH:
undetectable		 4p3rA-6chsH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_C_ACTC401_0
(PROTON-GATED ION
CHANNEL)		 6chs NPL4
(Chaetomium
thermophilum) 		4 / 7 ILE A 307
ARG A 282
ILE A 512
GLU A 513
 None
 0.93A 4zzbC-6chsA:
undetectable
4zzbD-6chsA:
undetectable		 4zzbC-6chsA:
undetectable
4zzbD-6chsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_A_ACTA401_0
(PROTON-GATED ION
CHANNEL)		 6chs NPL4
(Chaetomium
thermophilum) 		4 / 6 ILE A 307
ARG A 282
ILE A 512
GLU A 513
 None
 1.05A 4zzcA-6chsA:
undetectable
4zzcB-6chsA:
undetectable		 4zzcA-6chsA:
undetectable
4zzcB-6chsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_B_ACTB401_0
(PROTON-GATED ION
CHANNEL)		 6chs NPL4
(Chaetomium
thermophilum) 		4 / 6 ILE A 307
ARG A 282
ILE A 512
GLU A 513
 None
 1.02A 4zzcB-6chsA:
undetectable
4zzcC-6chsA:
undetectable		 4zzcB-6chsA:
undetectable
4zzcC-6chsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 6chs PUTATIVE CELL
DIVISION CONTROL
PROTEIN
(Chaetomium
thermophilum) 		4 / 5 ALA H 280
ARG H 241
ALA H 275
GLU H 237
 None
 1.34A 5a06C-6chsH:
undetectable
5a06D-6chsH:
undetectable		 5a06C-6chsH:
undetectable
5a06D-6chsH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGW_A_CTYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 6chs PUTATIVE CELL
DIVISION CONTROL
PROTEIN
(Chaetomium
thermophilum) 		5 / 12 ILE H 290
GLY H 287
GLU H 307
ILE H 317
PHE H 283
 None
 1.43A 5igwA-6chsH:
undetectable		 5igwA-6chsH:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGY_A_ERYA403_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 6chs PUTATIVE CELL
DIVISION CONTROL
PROTEIN
(Chaetomium
thermophilum) 		5 / 12 ILE H 319
GLY H 287
ASN H 286
GLU H 310
PHE H 282
 None
 0.98A 5igyA-6chsH:
undetectable		 5igyA-6chsH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ERYA404_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 6chs PUTATIVE CELL
DIVISION CONTROL
PROTEIN
(Chaetomium
thermophilum) 		5 / 12 ILE H 319
GLY H 287
ASN H 286
GLU H 310
PHE H 282
 None
 1.09A 5ih0A-6chsH:
undetectable		 5ih0A-6chsH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWY_A_YNUA1101_1
(MINERALOCORTICOID
RECEPTOR)		 6chs NPL4
(Chaetomium
thermophilum) 		4 / 6 GLN A 341
PHE A 401
THR A 347
PHE A 271
 None
 1.40A 5mwyA-6chsA:
undetectable		 5mwyA-6chsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUN_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 6chs NPL4
(Chaetomium
thermophilum) 		5 / 9 ALA A 263
VAL A 304
ILE A 345
LEU A 286
ILE A 416
 None
 0.93A 5nunA-6chsA:
undetectable		 5nunA-6chsA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VM8_B_SAMB301_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 6chs PUTATIVE CELL
DIVISION CONTROL
PROTEIN
(Chaetomium
thermophilum) 		6 / 10 GLY H 264
LEU H 258
ILE H 385
LEU H 259
THR H 268
ALA H 362
 AGS  H 901 (-3.2A)
None
None
None
MG  H 903 ( 3.5A)
None
 1.40A 5vm8B-6chsH:
undetectable		 5vm8B-6chsH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EFN_A_SAMA501_0
(SPORULATION KILLING
FACTOR MATURATION
PROTEIN SKFB)		 6chs PUTATIVE CELL
DIVISION CONTROL
PROTEIN
(Chaetomium
thermophilum) 		5 / 11 GLU H 769
ALA H 702
THR H 542
LEU H 544
ALA H 639
 None
AGS  H 902 (-3.5A)
MG  H 904 ( 3.3A)
None
None
 1.16A 6efnA-6chsH:
undetectable		 6efnA-6chsH:
undetectable