SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6cim'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_A_ESTA351_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 6cim V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 2
(Mus
musculus) 		5 / 12 SER B 104
LEU B  69
GLY B  96
PRO B  75
VAL B  45
 None
 1.11A 1fduA-6cimB:
undetectable		 1fduA-6cimB:
13.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_C_ESTC353_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 6cim V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 2
(Mus
musculus) 		5 / 12 SER B 104
LEU B  69
GLY B  96
PRO B  75
VAL B  45
 None
 1.05A 1fduC-6cimB:
undetectable		 1fduC-6cimB:
13.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FE2_A_LAXA700_1
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 6cim V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 2
(Mus
musculus) 		5 / 10 VAL B 182
TYR B 146
VAL B 145
ILE B 142
LEU B 184
 None
 1.18A 1fe2A-6cimB:
undetectable		 1fe2A-6cimB:
10.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9G_A_SAMA301_0
(HYPOTHETICAL PROTEIN
RV2118C)		 6cim V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 2
(Mus
musculus) 		5 / 12 ILE B 256
GLY B 221
SER B 259
LEU B 219
LEU B 200
 None
 0.93A 1i9gA-6cimB:
undetectable		 1i9gA-6cimB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X7H_A_PFNA1374_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 6cim V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 2
(Mus
musculus) 		4 / 6 LYS B 106
GLU B 126
TYR B 108
CYH B  67
 None
 1.47A 2x7hA-6cimB:
undetectable		 2x7hA-6cimB:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_A_SALA1302_1
(LYSR-TYPE REGULATORY
PROTEIN)		 6cim V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 2
(Mus
musculus) 		5 / 11 ILE B 185
GLY B 153
HIS B  94
PRO B 134
ILE B 142
 None
 1.43A 2y7kA-6cimB:
undetectable		 2y7kA-6cimB:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_B_SALB1304_1
(LYSR-TYPE REGULATORY
PROTEIN)		 6cim V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 2
(Mus
musculus) 		5 / 10 ILE B 185
GLY B 153
HIS B  94
PRO B 134
ILE B 142
 None
 1.44A 2y7kB-6cimB:
undetectable		 2y7kB-6cimB:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_A_097A801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 6cim V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 2
(Mus
musculus) 		5 / 9 ASP B 132
HIS B 140
HIS B  94
ILE B 185
LEU B 184
 None
 1.30A 3hy7A-6cimB:
undetectable		 3hy7A-6cimB:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_E_ACTE503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 6cim V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 2
(Mus
musculus) 		3 / 3 GLN B   4
THR B   7
ASN B  53
 None
 0.86A 3v4tE-6cimB:
undetectable		 3v4tE-6cimB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_B_DXCB1473_0
(MJ0495-LIKE PROTEIN)		 6cim V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 2
(Mus
musculus) 		5 / 11 ILE B  15
PHE B  19
PHE B 343
SER B 260
GLY B 319
 None
 1.08A 4ac9B-6cimB:
undetectable
4ac9C-6cimB:
undetectable		 4ac9B-6cimB:
undetectable
4ac9C-6cimB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV0_A_SAMA302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 6cim V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 2
(Mus
musculus) 		5 / 12 VAL B   8
ILE B 327
GLY B 330
GLY B 319
ILE B  15
 None
 1.02A 4iv0A-6cimB:
undetectable		 4iv0A-6cimB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA3_L_ACTL301_0
(C2095 HEAVY CHAIN
C2095 LIGHT CHAIN)		 6cim V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 2
(Mus
musculus) 		3 / 3 PRO B  59
ASN B  11
HIS B  10
 None
 0.89A 4ma3H-6cimB:
undetectable
4ma3L-6cimB:
undetectable		 4ma3H-6cimB:
undetectable
4ma3L-6cimB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_B_SAMB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 6cim V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 2
(Mus
musculus) 		5 / 12 VAL B   8
ILE B 327
GLY B 330
GLY B 319
ILE B  15
 None
 1.05A 4mwzB-6cimB:
undetectable		 4mwzB-6cimB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_N_EVPN2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 6cim V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 2
(Mus
musculus) 		4 / 6 GLU B 126
GLY B  18
ARG B  73
GLY B  32
 None
 0.89A 5cdnR-6cimB:
undetectable
5cdnS-6cimB:
undetectable		 5cdnR-6cimB:
10.82
5cdnS-6cimB:
13.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_4_BEZ4801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 6cim V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 2
(Mus
musculus) 		4 / 5 LEU B 289
ARG B 284
ILE B 273
ILE B 256
 None
 1.05A 5dzk4-6cimB:
undetectable
5dzkg-6cimB:
undetectable
5dzkm-6cimB:
undetectable
5dzkn-6cimB:
undetectable		 5dzk4-6cimB:
undetectable
5dzkg-6cimB:
undetectable
5dzkm-6cimB:
undetectable
5dzkn-6cimB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_V_BEZV801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 6cim V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 2
(Mus
musculus) 		4 / 4 ILE B 273
ILE B 256
ARG B 284
LEU B 289
 None
 1.16A 5dzkh-6cimB:
undetectable
5dzkn-6cimB:
undetectable
5dzkv-6cimB:
undetectable		 5dzkh-6cimB:
undetectable
5dzkn-6cimB:
undetectable
5dzkv-6cimB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_I_EY4I500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 6cim V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 2
(Mus
musculus) 		4 / 5 GLN B  33
VAL B  45
PRO B  37
THR B 121
 None
 1.37A 6cduI-6cimB:
undetectable
6cduJ-6cimB:
undetectable		 6cduI-6cimB:
undetectable
6cduJ-6cimB:
undetectable