SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6cj0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ERR_B_CCSB381_0 (ESTROGEN RECEPTOR)	6cj0	TREHALOSE PHOSPHATASE (Pseudomonas aeruginosa)	3 / 3	GLU A 248 ALA A 243 SER A 240	None	0.70A	1errB-6cj0A: undetectable	1errB-6cj0A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DRD_A_MIYA2001_1 (ACRB)	6cj0	TREHALOSE PHOSPHATASE (Pseudomonas aeruginosa)	6 / 9	GLY A 89 GLU A 142 ILE A 84 ALA A 198 VAL A 199 PHE A 227	None	1.41A	2drdA-6cj0A: 4.2	2drdA-6cj0A: 5.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3S3M_A_DLUA398_1 (PFV INTEGRASE)	6cj0	TREHALOSE PHOSPHATASE (Pseudomonas aeruginosa)	4 / 8	ASP A 11 ASP A 220 GLN A 48 ARG A 21	MG A 301 ( 2.3A) MG A 301 (-2.9A) None None	1.04A	3s3mA-6cj0A: undetectable	3s3mA-6cj0A: 10.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XJE_A_TOYA202_1 (AADB)	6cj0	TREHALOSE PHOSPHATASE (Pseudomonas aeruginosa)	4 / 8	ASP A 220 ASP A 11 ASP A 224 ILE A 84	MG A 301 (-2.9A) MG A 301 ( 2.3A) MG A 301 ( 4.6A) None	0.99A	4xjeA-6cj0A: undetectable	4xjeA-6cj0A: 19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CFS_A_TOYA203_1 (AAD(2''),GENTAMICIN 2''-NUCLEOTIDYLTRANS FERASE,GENTAMICIN RESISTANCE PROTEIN)	6cj0	TREHALOSE PHOSPHATASE (Pseudomonas aeruginosa)	4 / 8	ASP A 220 ASP A 11 ASP A 224 ILE A 84	MG A 301 (-2.9A) MG A 301 ( 2.3A) MG A 301 ( 4.6A) None	0.99A	5cfsA-6cj0A: undetectable	5cfsA-6cj0A: 19.57

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1ERR_B_CCSB381_0","ESTROGEN RECEPTOR","6cj0","TREHALOSE PHOSPHATASE","Pseudomonas aeruginosa",3,"GLU A 248;ALA A 243;SER A 240","None","0.70A","1errB-6cj0A:undetectable","1errB-6cj0A:undetectable"],["2DRD_A_MIYA2001_1","ACRB","6cj0","TREHALOSE PHOSPHATASE","Pseudomonas aeruginosa",6,"GLY A  89;GLU A 142;ILE A  84;ALA A 198;VAL A 199;PHE A 227","None","1.41A","2drdA-6cj0A:4.2","2drdA-6cj0A:5.94"],["3S3M_A_DLUA398_1","PFV INTEGRASE","6cj0","TREHALOSE PHOSPHATASE","Pseudomonas aeruginosa",4,"ASP A  11;ASP A 220;GLN A  48;ARG A  21"," MG A 301 ( 2.3A); MG A 301 (-2.9A);None;None","1.04A","3s3mA-6cj0A:undetectable","3s3mA-6cj0A:10.38"],["4XJE_A_TOYA202_1","AADB","6cj0","TREHALOSE PHOSPHATASE","Pseudomonas aeruginosa",4,"ASP A 220;ASP A  11;ASP A 224;ILE A  84"," MG A 301 (-2.9A); MG A 301 ( 2.3A); MG A 301 ( 4.6A);None","0.99A","4xjeA-6cj0A:undetectable","4xjeA-6cj0A:19.57"],["5CFS_A_TOYA203_1","AAD(2''),GENTAMICIN 2''-NUCLEOTIDYLTRANSFERASE,GENTAMICIN RESISTANCE PROTEIN","6cj0","TREHALOSE PHOSPHATASE","Pseudomonas aeruginosa",4,"ASP A 220;ASP A  11;ASP A 224;ILE A  84"," MG A 301 (-2.9A); MG A 301 ( 2.3A); MG A 301 ( 4.6A);None","0.99A","5cfsA-6cj0A:undetectable","5cfsA-6cj0A:19.57"]]