SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6cj7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_A_FUAA702_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6cj7 SERPIN-12
(Manduca
sexta) 		5 / 12 PHE A 215
LEU A 222
PHE A 347
ALA A  25
ALA A 363
 None
 1.21A 1q23A-6cj7A:
undetectable
1q23B-6cj7A:
undetectable		 1q23A-6cj7A:
14.16
1q23B-6cj7A:
14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_C_SAMC303_0
(HEMK PROTEIN)		 6cj7 SERPIN-12
(Manduca
sexta) 		5 / 12 ILE A  33
ALA A 306
VAL A 159
PRO A  28
ALA A  26
 None
 1.13A 1sg9C-6cj7A:
undetectable		 1sg9C-6cj7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9Y_A_FUNA500_1
(CARBONIC ANHYDRASE
II)		 6cj7 SERPIN-12
(Manduca
sexta) 		5 / 12 VAL A 280
PHE A 284
VAL A 303
LEU A  34
THR A  32
 None
 1.12A 1z9yA-6cj7A:
undetectable		 1z9yA-6cj7A:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		 6cj7 SERPIN-12
(Manduca
sexta) 		4 / 6 GLY A 183
PRO A 346
LYS A 345
THR A 180
 None
 1.27A 2m2oB-6cj7A:
undetectable		 2m2oB-6cj7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QJU_A_DSMA801_1
(TRANSPORTER)		 6cj7 SERPIN-12
(Manduca
sexta) 		5 / 11 LEU A  89
LEU A 111
ALA A 103
PHE A  99
LEU A  38
 None
 1.18A 2qjuA-6cj7A:
undetectable		 2qjuA-6cj7A:
10.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A9E_B_REAB1_1
(RETINOIC ACID
RECEPTOR ALPHA)		 6cj7 SERPIN-12
(Manduca
sexta) 		5 / 11 LEU A  34
ILE A  33
PHE A 107
SER A 109
LEU A  47
 None
 1.28A 3a9eB-6cj7A:
undetectable		 3a9eB-6cj7A:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E23_A_SAMA221_0
(UNCHARACTERIZED
PROTEIN RPA2492)		 6cj7 SERPIN-12
(Manduca
sexta) 		5 / 12 LEU A  89
PRO A  58
GLY A  41
GLY A 294
LEU A 290
 None
 1.04A 3e23A-6cj7A:
undetectable		 3e23A-6cj7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_B_ECNB602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 6cj7 SERPIN-12
(Manduca
sexta) 		5 / 9 LEU A  89
PHE A 107
ALA A  42
THR A  46
ILE A 283
 None
 1.43A 3jusB-6cj7A:
undetectable		 3jusB-6cj7A:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP5_A_KANA2001_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 6cj7 SERPIN-12
(Manduca
sexta) 		5 / 11 ASN A  69
GLN A  40
ALA A  62
GLU A  63
SER A  61
 None
 1.40A 3kp5A-6cj7A:
undetectable		 3kp5A-6cj7A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ0_X_DXCX75_0
(CYTOCHROME C7)		 6cj7 SERPIN-12
(Manduca
sexta) 		4 / 7 ILE A  72
LYS A 137
PHE A 161
GLY A 163
 None
 1.01A 3sj0X-6cj7A:
undetectable		 3sj0X-6cj7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BB2_B_STRB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 6cj7 SERPIN-12
(Manduca
sexta) 		5 / 11 ALA A 158
SER A 309
THR A 112
ILE A 126
ASN A 127
 None
 1.43A 4bb2A-6cj7A:
8.1
4bb2B-6cj7A:
undetectable		 4bb2A-6cj7A:
14.33
4bb2B-6cj7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIL_A_RBFA401_2
(MEMBRANE LIPOPROTEIN
TPN38(B))		 6cj7 SERPIN-12
(Manduca
sexta) 		4 / 8 PRO A 273
VAL A 274
GLN A  20
ILE A 269
 None
 0.97A 4iilA-6cj7A:
undetectable		 4iilA-6cj7A:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4I_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 6cj7 SERPIN-12
(Manduca
sexta) 		3 / 3 VAL A 311
ALA A 267
PHE A 361
 None
 0.83A 4z4iA-6cj7A:
undetectable		 4z4iA-6cj7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDY_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 6cj7 SERPIN-12
(Manduca
sexta) 		5 / 12 GLY A  44
GLY A   9
THR A  32
LEU A  54
THR A  46
 None
 1.24A 4zdyA-6cj7A:
undetectable		 4zdyA-6cj7A:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JS1_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 6cj7 SERPIN-12
(Manduca
sexta) 		3 / 3 VAL A 311
ALA A 267
PHE A 361
 None
 0.84A 5js1A-6cj7A:
undetectable		 5js1A-6cj7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_C_EPAC502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		 6cj7 SERPIN-12
(Manduca
sexta) 		4 / 8 LEU A 312
ILE A 314
PHE A 161
PHE A 215
 None
 0.88A 5m0oC-6cj7A:
undetectable		 5m0oC-6cj7A:
11.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 6cj7 SERPIN-12
(Manduca
sexta) 		4 / 4 GLN A 302
THR A 285
GLU A 272
LEU A  34
 None
 1.39A 5m66A-6cj7A:
undetectable		 5m66A-6cj7A:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 6cj7 SERPIN-12
(Manduca
sexta) 		4 / 4 GLN A 302
THR A 285
GLU A 272
LEU A  35
 None
 1.46A 5m66A-6cj7A:
undetectable		 5m66A-6cj7A:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UAN_B_REAB503_1
(RETINOIC ACID
RECEPTOR BETA)		 6cj7 SERPIN-12
(Manduca
sexta) 		5 / 12 LEU A  34
ILE A  33
PHE A 107
SER A 109
VAL A 280
 None
 1.25A 5uanB-6cj7A:
undetectable		 5uanB-6cj7A:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V5Z_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 6cj7 SERPIN-12
(Manduca
sexta) 		3 / 3 GLY A  41
THR A 151
PRO A 301
 None
 0.66A 5v5zA-6cj7A:
undetectable		 5v5zA-6cj7A:
10.82