SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6cjq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CD2_A_FOLA307_0
(DIHYDROFOLATE
REDUCTASE)		 6cjq -
(-) 		5 / 12 ILE A 329
ALA A 379
PHE A 366
ILE A 328
THR A 378
 None
 1.01A 1cd2A-6cjqA:
undetectable		 1cd2A-6cjqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKB_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 6cjq -
(-) 		5 / 12 GLU A 318
VAL A 320
ILE A 321
TYR A 259
ILE A 256
 None
 1.12A 1fkbA-6cjqA:
undetectable		 1fkbA-6cjqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_C_URFC999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 6cjq -
(-) 		4 / 5 ALA A 305
TYR A 404
ILE A 407
ASP A 312
 None
 1.16A 1upfC-6cjqA:
undetectable		 1upfC-6cjqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_A_STRA1001_2
(MINERALOCORTICOID
RECEPTOR)		 6cjq -
(-) 		4 / 4 LEU A  91
LEU A 100
SER A 105
LEU A  34
 None
None
None
PGW  A 505 ( 4.4A)
 1.18A 1ya3A-6cjqA:
undetectable		 1ya3A-6cjqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZN_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 6cjq -
(-) 		5 / 12 TYR A 404
ARG A 311
PHE A 302
GLY A 306
VAL A 299
 None
 1.25A 2zznA-6cjqA:
undetectable		 2zznA-6cjqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QGT_B_CP6B609_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 6cjq -
(-) 		5 / 10 ILE A 329
ALA A 379
ILE A 341
ILE A 328
THR A 378
 None
 1.25A 3qgtB-6cjqA:
undetectable		 3qgtB-6cjqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UY4_A_PAUA302_0
(PANTOTHENATE
SYNTHETASE)		 6cjq -
(-) 		4 / 8 HIS A 232
VAL A 236
VAL A 239
ASP A 261
 None
 1.15A 3uy4A-6cjqA:
2.8		 3uy4A-6cjqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AWU_A_4CHA502_0
(OXIDOREDUCTASE,
FMN-BINDING)		 6cjq -
(-) 		4 / 7 THR A  33
HIS A 149
LEU A 112
PHE A  96
 None
PGW  A 503 ( 4.9A)
PGW  A 505 ( 4.7A)
None
 1.19A 4awuA-6cjqA:
undetectable		 4awuA-6cjqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIM_A_CELA711_1
(LACTOTRANSFERRIN)		 6cjq -
(-) 		5 / 9 GLU A 271
VAL A 320
GLU A 258
TYR A 262
GLY A 323
 None
 1.44A 4fimA-6cjqA:
undetectable		 4fimA-6cjqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FN9_A_STRA301_1
(STEROID RECEPTOR 2)		 6cjq -
(-) 		5 / 12 LEU A  43
LEU A  46
LEU A  49
ALA A  50
ALA A  21
 None
 0.85A 4fn9A-6cjqA:
undetectable		 4fn9A-6cjqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUF_A_ACTA310_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 6cjq -
(-) 		3 / 3 GLN A 196
THR A 197
THR A 200
 None
 0.82A 4fufA-6cjqA:
undetectable		 4fufA-6cjqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_A_ACTA304_0
(GLUTATHIONE
TRANSFERASE GTE1)		 6cjq -
(-) 		4 / 5 ALA A 133
LEU A 225
LYS A 224
ASN A 131
 None
 0.96A 4g19A-6cjqA:
undetectable		 4g19A-6cjqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAR_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 6cjq -
(-) 		5 / 12 LEU A 112
CYH A 153
SER A 105
LEU A  93
THR A  33
 PGW  A 505 ( 4.7A)
None
None
None
None
 1.42A 4iarA-6cjqA:
4.3		 4iarA-6cjqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_A_CVIA608_0
(ACETYLCHOLINESTERASE)		 6cjq -
(-) 		4 / 7 ASP A  47
LEU A  46
VAL A  22
TYR A  26
 None
 1.10A 5ov9A-6cjqA:
2.7		 5ov9A-6cjqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIX_B_OQRB302_0
(SULFOTRANSFERASE)		 6cjq -
(-) 		5 / 10 ILE A  30
LEU A 107
VAL A  95
LEU A  94
ASP A  47
 None
 1.32A 5tixB-6cjqA:
undetectable		 5tixB-6cjqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZSF_A_6T0A910_0
(TOLL-LIKE RECEPTOR 7)		 6cjq -
(-) 		4 / 7 THR A 180
ILE A 189
THR A 190
TYR A 199
 None
 1.00A 5zsfA-6cjqA:
undetectable
5zsfB-6cjqA:
undetectable		 5zsfA-6cjqA:
undetectable
5zsfB-6cjqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		 6cjq -
(-) 		5 / 12 ILE A  30
LEU A 107
VAL A  95
ASP A  47
LEU A  43
 None
 1.12A 6b54A-6cjqA:
undetectable		 6b54A-6cjqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA825_0
(GEPHYRIN)		 6cjq -
(-) 		3 / 3 LYS A 114
VAL A 118
ASP A  84
 None
 0.68A 6fgdA-6cjqA:
undetectable		 6fgdA-6cjqA:
undetectable