SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6ckb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		 6ckb -
(-) 		7 / 10 LEU A 114
VAL A 215
ILE A 217
TYR A 239
LYS A 269
LEU A 280
GLU A 283
 None
 0.68A 1cqpA-6ckbA:
32.3
1cqpB-6ckbA:
32.2		 1cqpA-6ckbA:
undetectable
1cqpB-6ckbA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		 6ckb -
(-) 		5 / 7 LEU A 114
VAL A 215
TYR A 239
LYS A 269
LEU A 280
 None
 0.59A 1cqpA-6ckbA:
32.3
1cqpB-6ckbA:
32.2		 1cqpA-6ckbA:
undetectable
1cqpB-6ckbA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_PCFA1179_0
(WNT INHIBITORY
FACTOR 1)		 6ckb -
(-) 		5 / 12 LEU A 187
ILE A 219
ILE A 132
MET A 184
VAL A 197
 None
 0.92A 2ygnA-6ckbA:
undetectable		 2ygnA-6ckbA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F78_A_ICFA1_1
(INTEGRIN ALPHA-L)		 6ckb -
(-) 		6 / 9 ILE A 217
TYR A 239
ILE A 241
LYS A 269
LEU A 280
LYS A 287
 None
 1.03A 3f78A-6ckbA:
33.6		 3f78A-6ckbA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F78_B_ICFB2_1
(INTEGRIN ALPHA-L)		 6ckb -
(-) 		6 / 9 ILE A 217
TYR A 239
ILE A 241
LYS A 269
LEU A 280
LYS A 287
 None
 1.00A 3f78B-6ckbA:
33.9		 3f78B-6ckbA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK2_X_LDPX433_1
(6-HYDROXY-L-NICOTINE
OXIDASE)		 6ckb -
(-) 		4 / 7 TYR A 148
LEU A 178
LEU A 114
PHE A 281
 None
 1.29A 3nk2X-6ckbA:
undetectable		 3nk2X-6ckbA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KM9_B_ADNB201_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 2,
MITOCHONDRIAL)		 6ckb -
(-) 		5 / 12 ILE A 194
PHE A 259
ILE A 218
LEU A 117
SER A 227
 None
 1.23A 5km9B-6ckbA:
undetectable		 5km9B-6ckbA:
undetectable