SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6ckv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHS_A_CLMA888_0
(PROTEIN
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE))		 6ckv BCL-2-RELATED
OVARIAN KILLER
PROTEIN
(Homo
sapiens) 		4 / 5 PRO A 143
MET A 145
ALA A 148
GLU A  99
 None
 1.31A 1qhsA-6ckvA:
undetectable		 1qhsA-6ckvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHY_A_CLMA888_0
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE)		 6ckv BCL-2-RELATED
OVARIAN KILLER
PROTEIN
(Homo
sapiens) 		4 / 6 PRO A 143
MET A 145
ALA A 148
GLU A  99
 None
 1.30A 1qhyA-6ckvA:
undetectable		 1qhyA-6ckvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_C_478C200_1
(PROTEASE)		 6ckv BCL-2-RELATED
OVARIAN KILLER
PROTEIN
(Homo
sapiens) 		6 / 10 LEU A 133
ALA A 105
ASP A 104
GLY A 111
ILE A 113
ALA A 130
 None
 1.30A 3ekpC-6ckvA:
undetectable		 3ekpC-6ckvA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GGU_B_017B201_2
(PROTEASE)		 6ckv BCL-2-RELATED
OVARIAN KILLER
PROTEIN
(Homo
sapiens) 		5 / 9 LEU A 133
ALA A 105
ASP A 104
GLY A 111
ILE A 113
 None
 1.09A 3gguB-6ckvA:
undetectable		 3gguB-6ckvA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_A_TPVA100_1
(HIV-1 PROTEASE)		 6ckv BCL-2-RELATED
OVARIAN KILLER
PROTEIN
(Homo
sapiens) 		5 / 11 LEU A 133
ALA A 105
ASP A 104
GLY A 111
ILE A 113
 None
 1.15A 3spkA-6ckvA:
undetectable		 3spkA-6ckvA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I1R_A_LZUA801_1
(MUCOSA-ASSOCIATED
LYMPHOID TISSUE
LYMPHOMA
TRANSLOCATION
PROTEIN 1)		 6ckv BCL-2-RELATED
OVARIAN KILLER
PROTEIN
(Homo
sapiens) 		5 / 12 LEU A  63
VAL A  59
ALA A  33
GLU A  37
LEU A  71
 None
 1.07A 4i1rA-6ckvA:
undetectable		 4i1rA-6ckvA:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NSB_A_AINA402_1
(CHITINASE-3-LIKE
PROTEIN 1)		 6ckv BCL-2-RELATED
OVARIAN KILLER
PROTEIN
(Homo
sapiens) 		4 / 7 TRP A 164
TRP A 120
TRP A 171
LEU A  27
 None
 1.24A 4nsbA-6ckvA:
undetectable		 4nsbA-6ckvA:
11.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDQ_A_BEZA306_0
(GLYCOSIDE HYDROLASE
FAMILY PROTEIN)		 6ckv BCL-2-RELATED
OVARIAN KILLER
PROTEIN
(Homo
sapiens) 		3 / 3 ARG A 168
ASP A 173
TRP A 120
 None
 1.19A 4xdqA-6ckvA:
undetectable		 4xdqA-6ckvA:
undetectable