SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6cl5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KGL_A_RTLA175_1
(CELLULAR
RETINOL-BINDING
PROTEIN TYPE I)
6cl5 TAIL FIBER PROTEIN
(Pseudomonas
aeruginosa)
4 / 7 ILE A 393
THR A 379
TRP A 436
GLN A 407
None
1.08A 1kglA-6cl5A:
undetectable
1kglA-6cl5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_H_BEZH515_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)
6cl5 TAIL FIBER PROTEIN
(Pseudomonas
aeruginosa)
4 / 6 PHE A 397
ARG A 431
ALA A 405
ILE A 393
None
1.22A 1oniH-6cl5A:
undetectable
1oniI-6cl5A:
undetectable
1oniH-6cl5A:
undetectable
1oniI-6cl5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1160_1
(ALLERGEN ARG R 1)
6cl5 TAIL FIBER PROTEIN
(Pseudomonas
aeruginosa)
4 / 7 SER A 461
VAL A 492
ILE A 459
TRP A 468
None
1.24A 2x45B-6cl5A:
undetectable
2x45B-6cl5A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1160_1
(ALLERGEN ARG R 1)
6cl5 TAIL FIBER PROTEIN
(Pseudomonas
aeruginosa)
4 / 7 SER A 461
VAL A 492
ILE A 459
TRP A 468
None
1.25A 2x45C-6cl5A:
undetectable
2x45C-6cl5A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2P_A_ACTA1728_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9)
6cl5 TAIL FIBER PROTEIN
(Pseudomonas
aeruginosa)
4 / 5 THR A 599
TRP A 608
ASP A 610
ASN A 611
None
1.48A 5b2pA-6cl5A:
0.1
5b2pA-6cl5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2Q_A_ACTA1729_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9)
6cl5 TAIL FIBER PROTEIN
(Pseudomonas
aeruginosa)
4 / 5 THR A 599
TRP A 608
ASP A 610
ASN A 611
None
1.49A 5b2qA-6cl5A:
undetectable
5b2qA-6cl5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA607_1
(PHIAB6 TAILSPIKE)
6cl5 TAIL FIBER PROTEIN
(Pseudomonas
aeruginosa)
3 / 3 THR A 506
SER A 510
TYR A 512
None
0.86A 5jsdA-6cl5A:
3.3
5jsdA-6cl5A:
8.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB618_1
(PHIAB6 TAILSPIKE)
6cl5 TAIL FIBER PROTEIN
(Pseudomonas
aeruginosa)
3 / 3 THR A 506
SER A 510
TYR A 512
None
0.86A 5jsdB-6cl5A:
undetectable
5jsdB-6cl5A:
8.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_C_1GNC608_1
(PHIAB6 TAILSPIKE)
6cl5 TAIL FIBER PROTEIN
(Pseudomonas
aeruginosa)
3 / 3 THR A 506
SER A 510
TYR A 512
None
0.86A 5jsdC-6cl5A:
undetectable
5jsdC-6cl5A:
8.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_A_1GNA608_1
(PHIAB6 TAILSPIKE)
6cl5 TAIL FIBER PROTEIN
(Pseudomonas
aeruginosa)
3 / 3 THR A 506
SER A 510
TYR A 512
None
0.85A 5jseA-6cl5A:
3.3
5jseA-6cl5A:
8.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_B_1GNB611_1
(PHIAB6 TAILSPIKE)
6cl5 TAIL FIBER PROTEIN
(Pseudomonas
aeruginosa)
3 / 3 THR A 506
SER A 510
TYR A 512
None
0.86A 5jseB-6cl5A:
undetectable
5jseB-6cl5A:
8.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_C_1GNC611_1
(PHIAB6 TAILSPIKE)
6cl5 TAIL FIBER PROTEIN
(Pseudomonas
aeruginosa)
3 / 3 THR A 506
SER A 510
TYR A 512
None
0.86A 5jseC-6cl5A:
undetectable
5jseC-6cl5A:
8.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_V_6V8V303_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)
6cl5 TAIL FIBER PROTEIN
(Pseudomonas
aeruginosa)
5 / 11 ALA A 372
THR A 371
GLY A 403
ALA A 405
LEU A 434
None
0.97A 5lf7V-6cl5A:
2.1
5lf7W-6cl5A:
undetectable
5lf7V-6cl5A:
undetectable
5lf7W-6cl5A:
undetectable