SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6cmn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM9_A_9CRA201_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 6cmn TAR-BINDING PROTEIN
6.7
(Oryctolagus
cuniculus) 		3 / 3 GLN A  54
ILE A  40
HIS A  31
 A  D  35 ( 2.9A)
None
None
 0.60A 1fm9A-6cmnA:
undetectable		 1fm9A-6cmnA:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K74_A_9CRA463_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 6cmn TAR-BINDING PROTEIN
6.7
(Oryctolagus
cuniculus) 		3 / 3 GLN A  54
ILE A  40
HIS A  31
 A  D  35 ( 2.9A)
None
None
 0.57A 1k74A-6cmnA:
undetectable		 1k74A-6cmnA:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B2R_A_VDNA1_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 6cmn TAR-BINDING PROTEIN
6.7
(Oryctolagus
cuniculus) 		5 / 12 ILE A  21
LEU A  30
ALA A  32
ILE A  33
PHE A  77
 None
 0.97A 3b2rA-6cmnA:
undetectable		 3b2rA-6cmnA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B2R_B_VDNB1_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 6cmn TAR-BINDING PROTEIN
6.7
(Oryctolagus
cuniculus) 		5 / 11 ILE A  21
LEU A  30
ALA A  32
ILE A  33
PHE A  77
 None
 0.95A 3b2rB-6cmnA:
undetectable		 3b2rB-6cmnA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX7_A_DM2A1106_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 6cmn TAR-BINDING PROTEIN
6.7
(Oryctolagus
cuniculus) 		5 / 11 MET A  72
PHE A  34
PHE A  75
ASN A  16
LEU A  17
 None
 1.36A 4dx7A-6cmnA:
3.4		 4dx7A-6cmnA:
4.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_B_9CRB501_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 6cmn TAR-BINDING PROTEIN
6.7
(Oryctolagus
cuniculus) 		3 / 3 GLN A  54
ILE A  40
HIS A  31
 A  D  35 ( 2.9A)
None
None
 0.60A 5z12B-6cmnA:
undetectable		 5z12B-6cmnA:
15.66