SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6cn1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1E06_B_IPBB600_0 (ODORANT-BINDING PROTEIN)	6cn1	UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE (Pseudomonas putida)	4 / 4	ILE A 62 MET A 53 VAL A 111 GLY A 58	None	1.37A	1e06B-6cn1A: undetectable	1e06B-6cn1A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1I18_A_RBFA98_1 (RIBOFLAVIN SYNTHASE ALPHA CHAIN)	6cn1	UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE (Pseudomonas putida)	5 / 10	LEU A 266 THR A 238 ILE A 18 THR A 257 ILE A 261	None	1.42A	1i18A-6cn1A: undetectable 1i18B-6cn1A: undetectable	1i18A-6cn1A: 24.74 1i18B-6cn1A: 24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1I18_B_RBFB99_1 (RIBOFLAVIN SYNTHASE ALPHA CHAIN)	6cn1	UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE (Pseudomonas putida)	5 / 10	ILE A 261 LEU A 266 THR A 238 ILE A 18 THR A 257	None	1.41A	1i18A-6cn1A: undetectable 1i18B-6cn1A: undetectable	1i18A-6cn1A: 24.74 1i18B-6cn1A: 24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KIJ_A_NOVA400_2 (DNA GYRASE SUBUNIT B)	6cn1	UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE (Pseudomonas putida)	3 / 3	ASN A 317 PHE A 335 VAL A 326	None	0.86A	1kijA-6cn1A: undetectable	1kijA-6cn1A: 12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MRG_A_ADNA300_1 (ALPHA-MOMORCHARIN)	6cn1	UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE (Pseudomonas putida)	5 / 9	ILE A 398 GLY A 401 ILE A 405 GLU A 406 ARG A 418	None	1.12A	1mrgA-6cn1A: undetectable	1mrgA-6cn1A: 20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YA4_B_CTXB2_2 (CES1 PROTEIN)	6cn1	UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE (Pseudomonas putida)	4 / 4	LEU A 131 PRO A 27 ILE A 96 LEU A 99	None	1.14A	1ya4B-6cn1A: 0.7	1ya4B-6cn1A: 12.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YAJ_B_BEZB12_0 (CES1 PROTEIN)	6cn1	UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE (Pseudomonas putida)	4 / 4	GLY A 168 SER A 165 VAL A 194 LEU A 97	None EPU A 501 (-2.5A) None None	1.25A	1yajB-6cn1A: undetectable	1yajB-6cn1A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2H77_A_T3A1_1 (THRA PROTEIN)	6cn1	UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE (Pseudomonas putida)	5 / 12	ILE A 172 ALA A 175 ALA A 147 LEU A 99 PHE A 159	None	1.08A	2h77A-6cn1A: undetectable	2h77A-6cn1A: 15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2H79_A_T3A1_1 (THRA PROTEIN)	6cn1	UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE (Pseudomonas putida)	5 / 12	ILE A 172 ALA A 175 ALA A 147 LEU A 99 PHE A 159	None	1.09A	2h79A-6cn1A: undetectable	2h79A-6cn1A: 15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OAX_A_SNLA1001_2 (MINERALOCORTICOID RECEPTOR)	6cn1	UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE (Pseudomonas putida)	4 / 5	LEU A 29 ALA A 31 LEU A 197 MET A 232	None	1.25A	2oaxA-6cn1A: undetectable	2oaxA-6cn1A: 14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YY8_B_SAMB500_0 (UPF0106 PROTEIN PH0461)	6cn1	UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE (Pseudomonas putida)	5 / 11	LEU A 363 GLY A 388 ILE A 319 GLU A 387 ALA A 362	None	1.16A	2yy8A-6cn1A: undetectable 2yy8B-6cn1A: undetectable	2yy8A-6cn1A: undetectable 2yy8B-6cn1A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3H5G_A_LEIA16_0 (COIL SER L16D-PEN)	6cn1	UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE (Pseudomonas putida)	4 / 6	LYS A 408 GLN A 410 LEU A 412 LEU A 12	None	0.89A	3h5gA-6cn1A: undetectable 3h5gC-6cn1A: undetectable	3h5gA-6cn1A: undetectable 3h5gC-6cn1A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HEG_A_BAXA1_2 (MITOGEN-ACTIVATED PROTEIN KINASE 14)	6cn1	UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE (Pseudomonas putida)	4 / 6	MET A 344 VAL A 368 ILE A 392 LEU A 391	None	0.75A	3hegA-6cn1A: undetectable	3hegA-6cn1A: 13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IV6_B_SAMB301_0 (PUTATIVE ZN-DEPENDENT ALCOHOL DEHYDROGENASE)	6cn1	UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE (Pseudomonas putida)	5 / 12	GLY A 210 THR A 213 ASP A 219 ILE A 218 ASP A 214	None	1.22A	3iv6B-6cn1A: undetectable	3iv6B-6cn1A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IV6_D_SAMD301_0 (PUTATIVE ZN-DEPENDENT ALCOHOL DEHYDROGENASE)	6cn1	UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE (Pseudomonas putida)	5 / 12	GLY A 210 THR A 213 ASP A 219 ILE A 218 ASP A 214	None	1.28A	3iv6D-6cn1A: undetectable	3iv6D-6cn1A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NDW_A_RITA100_2 (PROTEASE)	6cn1	UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE (Pseudomonas putida)	5 / 9	ARG A 129 ALA A 175 ILE A 218 GLY A 156 ILE A 172	None	1.12A	3ndwB-6cn1A: undetectable	3ndwB-6cn1A: 22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3R9C_A_ECLA452_1 (CYTOCHROME P450 164A2)	6cn1	UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE (Pseudomonas putida)	5 / 12	SER A 315 LEU A 384 LEU A 12 VAL A 252 LEU A 285	None	1.12A	3r9cA-6cn1A: undetectable	3r9cA-6cn1A: 11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UT5_D_LOCD502_1 (TUBULIN BETA CHAIN)	6cn1	UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE (Pseudomonas putida)	5 / 12	ALA A 149 LEU A 131 ALA A 175 ALA A 179 ILE A 172	None	1.19A	3ut5D-6cn1A: undetectable	3ut5D-6cn1A: 13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V4T_E_ACTE502_0 (UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE)	6cn1	UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE (Pseudomonas putida)	3 / 3	LYS A 22 ARG A 122 LEU A 373	EPU A 501 (-4.1A) EPU A 501 (-3.9A) EPU A 501 (-4.6A)	1.07A	3v4tE-6cn1A: 63.6	3v4tE-6cn1A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V4T_H_ACTH503_0 (UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE)	6cn1	UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE (Pseudomonas putida)	5 / 7	ARG A 93 ALA A 94 ILE A 96 ARG A 122 HIS A 127	None EPU A 501 (-3.6A) None EPU A 501 (-3.9A) None	0.60A	3v4tH-6cn1A: 63.8	3v4tH-6cn1A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V4T_H_ACTH503_0 (UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE)	6cn1	UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE (Pseudomonas putida)	4 / 7	ILE A 96 ARG A 122 HIS A 127 GLY A 168	None EPU A 501 (-3.9A) None None	1.01A	3v4tH-6cn1A: 63.8	3v4tH-6cn1A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W1W_A_CHDA1507_0 (FERROCHELATASE, MITOCHONDRIAL)	6cn1	UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE (Pseudomonas putida)	3 / 3	ARG A 374 LYS A 22 ARG A 400	None EPU A 501 (-4.1A) 0V5 A 502 (-3.0A)	1.48A	3w1wA-6cn1A: undetectable 3w1wB-6cn1A: undetectable	3w1wA-6cn1A: undetectable 3w1wB-6cn1A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W1W_B_CHDB506_0 (FERROCHELATASE, MITOCHONDRIAL)	6cn1	UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE (Pseudomonas putida)	3 / 3	ARG A 400 ARG A 374 LYS A 22	0V5 A 502 (-3.0A) None EPU A 501 (-4.1A)	1.47A	3w1wA-6cn1A: undetectable 3w1wB-6cn1A: undetectable	3w1wA-6cn1A: undetectable 3w1wB-6cn1A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WIP_G_ACTG305_0 (ACETYLCHOLINE-BINDIN G PROTEIN)	6cn1	UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE (Pseudomonas putida)	3 / 3	ASP A 281 ARG A 17 LYS A 255	None	1.20A	3wipG-6cn1A: undetectable	3wipG-6cn1A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FE1_A_PQNA846_1 (PHOTOSYSTEM I P700 CHLOROPHYLL A APOPROTEIN A1 PHOTOSYSTEM I REACTION CENTER SUBUNIT IX)	6cn1	UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE (Pseudomonas putida)	5 / 10	PHE A 57 LEU A 56 GLY A 58 ALA A 136 MET A 134	None	1.48A	4fe1A-6cn1A: undetectable 4fe1J-6cn1A: undetectable	4fe1A-6cn1A: 8.67 4fe1J-6cn1A: 27.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_C_CLQC303_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	6cn1	UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE (Pseudomonas putida)	4 / 8	ASN A 317 GLY A 324 VAL A 357 ILE A 327	None	0.90A	4fglD-6cn1A: undetectable	4fglD-6cn1A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4J24_A_ESTA600_1 (ESTROGEN RECEPTOR BETA)	6cn1	UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE (Pseudomonas putida)	5 / 12	LEU A 97 GLU A 170 LEU A 197 ILE A 74 LEU A 34	None EPU A 501 ( 4.9A) None None None	1.14A	4j24A-6cn1A: undetectable	4j24A-6cn1A: 18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4J24_B_ESTB600_1 (ESTROGEN RECEPTOR BETA)	6cn1	UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE (Pseudomonas putida)	5 / 12	LEU A 97 GLU A 170 LEU A 197 ILE A 74 LEU A 34	None EPU A 501 ( 4.9A) None None None	1.10A	4j24B-6cn1A: undetectable	4j24B-6cn1A: 18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4J24_C_ESTC600_1 (ESTROGEN RECEPTOR BETA)	6cn1	UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE (Pseudomonas putida)	5 / 12	LEU A 97 GLU A 170 LEU A 197 ILE A 74 LEU A 34	None EPU A 501 ( 4.9A) None None None	1.14A	4j24C-6cn1A: undetectable	4j24C-6cn1A: 18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LBG_B_ADNB402_1 (PROBABLE SUGAR KINASE PROTEIN)	6cn1	UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE (Pseudomonas putida)	5 / 9	ALA A 346 ILE A 319 VAL A 247 ALA A 383 ALA A 386	None	1.07A	4lbgB-6cn1A: undetectable	4lbgB-6cn1A: 15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LNW_A_T3A501_1 (THYROID HORMONE RECEPTOR ALPHA)	6cn1	UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE (Pseudomonas putida)	5 / 12	ILE A 172 ALA A 175 ALA A 147 LEU A 99 PHE A 159	None	1.10A	4lnwA-6cn1A: undetectable	4lnwA-6cn1A: 16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LNX_A_T3A502_1 (THYROID HORMONE RECEPTOR ALPHA)	6cn1	UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE (Pseudomonas putida)	5 / 12	ILE A 172 ALA A 175 ALA A 147 LEU A 99 PHE A 159	None	1.11A	4lnxA-6cn1A: undetectable	4lnxA-6cn1A: 16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RP9_A_ASCA501_0 (ASCORBATE-SPECIFIC PERMEASE IIC COMPONENT ULAA)	6cn1	UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE (Pseudomonas putida)	5 / 12	THR A 299 GLN A 310 ASP A 372 ILE A 330 PHE A 331	None None None EPU A 501 (-4.8A) EPU A 501 (-4.8A)	1.39A	4rp9A-6cn1A: undetectable	4rp9A-6cn1A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U8V_B_MIYB1103_1 (MULTIDRUG EFFLUX PUMP SUBUNIT ACRB)	6cn1	UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE (Pseudomonas putida)	5 / 12	GLY A 401 ILE A 398 ALA A 377 VAL A 380 ARG A 418	None	1.08A	4u8vB-6cn1A: undetectable	4u8vB-6cn1A: 8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U8Y_B_MIYB1102_1 (MULTIDRUG EFFLUX PUMP SUBUNIT ACRB)	6cn1	UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE (Pseudomonas putida)	5 / 12	GLY A 401 ILE A 398 ALA A 377 VAL A 380 ARG A 418	None	1.09A	4u8yB-6cn1A: undetectable	4u8yB-6cn1A: 8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZO1_X_T3X500_1 (THYROID HORMONE RECEPTOR BETA)	6cn1	UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE (Pseudomonas putida)	5 / 12	ILE A 172 ALA A 175 ALA A 147 LEU A 99 PHE A 159	None	1.18A	4zo1X-6cn1A: undetectable	4zo1X-6cn1A: 16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZVM_A_DM2A303_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	6cn1	UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE (Pseudomonas putida)	5 / 12	GLY A 324 THR A 323 ILE A 356 GLN A 310 ILE A 314	None	1.21A	4zvmA-6cn1A: undetectable 4zvmB-6cn1A: undetectable	4zvmA-6cn1A: 18.36 4zvmB-6cn1A: 18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DLV_A_5D5A930_0 (ECTONUCLEOTIDE PYROPHOSPHATASE/PHOS PHODIESTERASE FAMILY MEMBER 2)	6cn1	UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE (Pseudomonas putida)	5 / 12	LEU A 297 THR A 238 LEU A 242 ILE A 319 PHE A 313	None	1.35A	5dlvA-6cn1A: undetectable	5dlvA-6cn1A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HS6_A_J3ZA302_1 (17-BETA-HYDROXYSTERO ID DEHYDROGENASE 14)	6cn1	UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE (Pseudomonas putida)	4 / 8	HIS A 337 GLN A 310 LEU A 379 THR A 240	None	0.97A	5hs6A-6cn1A: undetectable	5hs6A-6cn1A: 18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IKR_A_ID8A601_2 (PROSTAGLANDIN G/H SYNTHASE 2)	6cn1	UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE (Pseudomonas putida)	3 / 3	VAL A 140 LEU A 154 MET A 134	None	0.78A	5ikrA-6cn1A: undetectable	5ikrA-6cn1A: 15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KB5_A_ADNA401_1 (ADENOSINE KINASE)	6cn1	UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE (Pseudomonas putida)	5 / 12	LEU A 269 GLY A 289 GLY A 249 ALA A 274 LEU A 285	None	0.96A	5kb5A-6cn1A: undetectable	5kb5A-6cn1A: 13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LJB_A_RTLA201_1 (RETINOL-BINDING PROTEIN 1)	6cn1	UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE (Pseudomonas putida)	4 / 8	LEU A 4 LEU A 384 ILE A 236 THR A 240	None	1.03A	5ljbA-6cn1A: undetectable	5ljbA-6cn1A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UMD_A_YMZA3801_1 (60S RIBOSOMAL PROTEIN L28 28S RIBOSOMAL RNA 60S RIBOSOMAL PROTEIN L4)	6cn1	UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE (Pseudomonas putida)	4 / 6	ALA A 94 PRO A 114 VAL A 89 ASP A 49	EPU A 501 (-3.6A) None None None	0.90A	5umd2-6cn1A: undetectable 5umdF-6cn1A: undetectable	5umd2-6cn1A: 18.07 5umdF-6cn1A: 19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AK3_B_P2EB1201_1 (PROSTAGLANDIN E2 RECEPTOR EP3 SUBTYPE,SOLUBLE CYTOCHROME B562)	6cn1	UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE (Pseudomonas putida)	4 / 5	PRO A 301 VAL A 164 GLY A 210 VAL A 194	None	1.10A	6ak3B-6cn1A: undetectable	6ak3B-6cn1A: 26.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MDQ_A_TESA604_0 (SERUM ALBUMIN)	6cn1	UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE (Pseudomonas putida)	4 / 8	ALA A 175 GLY A 130 LEU A 131 ALA A 136	None	0.83A	6mdqA-6cn1A: undetectable	6mdqA-6cn1A: 18.68

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1E06_B_IPBB600_0","ODORANT-BINDING PROTEIN","6cn1","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","Pseudomonas putida",4,"ILE A  62;MET A  53;VAL A 111;GLY A  58","None","1.37A","1e06B-6cn1A:undetectable","1e06B-6cn1A:undetectable"],["1I18_A_RBFA98_1","RIBOFLAVIN SYNTHASE ALPHA CHAIN;RIBOFLAVIN SYNTHASE ALPHA CHAIN","6cn1","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","Pseudomonas putida",5,"LEU A 266;THR A 238;ILE A  18;THR A 257;ILE A 261","None","1.42A","1i18A-6cn1A:undetectable;1i18B-6cn1A:undetectable","1i18A-6cn1A:24.74;1i18B-6cn1A:24.74"],["1I18_B_RBFB99_1","RIBOFLAVIN SYNTHASE ALPHA CHAIN;RIBOFLAVIN SYNTHASE ALPHA CHAIN","6cn1","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","Pseudomonas putida",5,"ILE A 261;LEU A 266;THR A 238;ILE A  18;THR A 257","None","1.41A","1i18A-6cn1A:undetectable;1i18B-6cn1A:undetectable","1i18A-6cn1A:24.74;1i18B-6cn1A:24.74"],["1KIJ_A_NOVA400_2","DNA GYRASE SUBUNIT B","6cn1","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","Pseudomonas putida",3,"ASN A 317;PHE A 335;VAL A 326","None","0.86A","1kijA-6cn1A:undetectable","1kijA-6cn1A:12.12"],["1MRG_A_ADNA300_1","ALPHA-MOMORCHARIN","6cn1","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","Pseudomonas putida",5,"ILE A 398;GLY A 401;ILE A 405;GLU A 406;ARG A 418","None","1.12A","1mrgA-6cn1A:undetectable","1mrgA-6cn1A:20.18"],["1YA4_B_CTXB2_2","CES1 PROTEIN","6cn1","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","Pseudomonas putida",4,"LEU A 131;PRO A  27;ILE A  96;LEU A  99","None","1.14A","1ya4B-6cn1A:0.7","1ya4B-6cn1A:12.19"],["1YAJ_B_BEZB12_0","CES1 PROTEIN","6cn1","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","Pseudomonas putida",4,"GLY A 168;SER A 165;VAL A 194;LEU A  97","None;EPU A 501 (-2.5A);None;None","1.25A","1yajB-6cn1A:undetectable","1yajB-6cn1A:undetectable"],["2H77_A_T3A1_1","THRA PROTEIN","6cn1","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","Pseudomonas putida",5,"ILE A 172;ALA A 175;ALA A 147;LEU A  99;PHE A 159","None","1.08A","2h77A-6cn1A:undetectable","2h77A-6cn1A:15.47"],["2H79_A_T3A1_1","THRA PROTEIN","6cn1","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","Pseudomonas putida",5,"ILE A 172;ALA A 175;ALA A 147;LEU A  99;PHE A 159","None","1.09A","2h79A-6cn1A:undetectable","2h79A-6cn1A:15.47"],["2OAX_A_SNLA1001_2","MINERALOCORTICOID RECEPTOR","6cn1","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","Pseudomonas putida",4,"LEU A  29;ALA A  31;LEU A 197;MET A 232","None","1.25A","2oaxA-6cn1A:undetectable","2oaxA-6cn1A:14.62"],["2YY8_B_SAMB500_0","UPF0106 PROTEIN PH0461","6cn1","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","Pseudomonas putida",5,"LEU A 363;GLY A 388;ILE A 319;GLU A 387;ALA A 362","None","1.16A","2yy8A-6cn1A:undetectable;2yy8B-6cn1A:undetectable","2yy8A-6cn1A:undetectable;2yy8B-6cn1A:undetectable"],["3H5G_A_LEIA16_0","COIL SER L16D-PEN","6cn1","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","Pseudomonas putida",4,"LYS A 408;GLN A 410;LEU A 412;LEU A  12","None","0.89A","3h5gA-6cn1A:undetectable;3h5gC-6cn1A:undetectable","3h5gA-6cn1A:undetectable;3h5gC-6cn1A:undetectable"],["3HEG_A_BAXA1_2","MITOGEN-ACTIVATED PROTEIN KINASE 14","6cn1","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","Pseudomonas putida",4,"MET A 344;VAL A 368;ILE A 392;LEU A 391","None","0.75A","3hegA-6cn1A:undetectable","3hegA-6cn1A:13.51"],["3IV6_B_SAMB301_0","PUTATIVE ZN-DEPENDENT ALCOHOL DEHYDROGENASE","6cn1","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","Pseudomonas putida",5,"GLY A 210;THR A 213;ASP A 219;ILE A 218;ASP A 214","None","1.22A","3iv6B-6cn1A:undetectable","3iv6B-6cn1A:undetectable"],["3IV6_D_SAMD301_0","PUTATIVE ZN-DEPENDENT ALCOHOL DEHYDROGENASE","6cn1","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","Pseudomonas putida",5,"GLY A 210;THR A 213;ASP A 219;ILE A 218;ASP A 214","None","1.28A","3iv6D-6cn1A:undetectable","3iv6D-6cn1A:undetectable"],["3NDW_A_RITA100_2","PROTEASE;PROTEASE","6cn1","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","Pseudomonas putida",5,"ARG A 129;ALA A 175;ILE A 218;GLY A 156;ILE A 172","None","1.12A","3ndwB-6cn1A:undetectable","3ndwB-6cn1A:22.92"],["3R9C_A_ECLA452_1","CYTOCHROME P450 164A2","6cn1","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","Pseudomonas putida",5,"SER A 315;LEU A 384;LEU A  12;VAL A 252;LEU A 285","None","1.12A","3r9cA-6cn1A:undetectable","3r9cA-6cn1A:11.03"],["3UT5_D_LOCD502_1","TUBULIN BETA CHAIN","6cn1","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","Pseudomonas putida",5,"ALA A 149;LEU A 131;ALA A 175;ALA A 179;ILE A 172","None","1.19A","3ut5D-6cn1A:undetectable","3ut5D-6cn1A:13.39"],["3V4T_E_ACTE502_0","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","6cn1","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","Pseudomonas putida",3,"LYS A  22;ARG A 122;LEU A 373","EPU A 501 (-4.1A);EPU A 501 (-3.9A);EPU A 501 (-4.6A)","1.07A","3v4tE-6cn1A:63.6","3v4tE-6cn1A:undetectable"],["3V4T_H_ACTH503_0","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","6cn1","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","Pseudomonas putida",5,"ARG A  93;ALA A  94;ILE A  96;ARG A 122;HIS A 127","None;EPU A 501 (-3.6A);None;EPU A 501 (-3.9A);None","0.60A","3v4tH-6cn1A:63.8","3v4tH-6cn1A:undetectable"],["3V4T_H_ACTH503_0","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","6cn1","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","Pseudomonas putida",4,"ILE A  96;ARG A 122;HIS A 127;GLY A 168","None;EPU A 501 (-3.9A);None;None","1.01A","3v4tH-6cn1A:63.8","3v4tH-6cn1A:undetectable"],["3W1W_A_CHDA1507_0","FERROCHELATASE, MITOCHONDRIAL","6cn1","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","Pseudomonas putida",3,"ARG A 374;LYS A  22;ARG A 400","None;EPU A 501 (-4.1A);0V5 A 502 (-3.0A)","1.48A","3w1wA-6cn1A:undetectable;3w1wB-6cn1A:undetectable","3w1wA-6cn1A:undetectable;3w1wB-6cn1A:undetectable"],["3W1W_B_CHDB506_0","FERROCHELATASE, MITOCHONDRIAL","6cn1","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","Pseudomonas putida",3,"ARG A 400;ARG A 374;LYS A  22","0V5 A 502 (-3.0A);None;EPU A 501 (-4.1A)","1.47A","3w1wA-6cn1A:undetectable;3w1wB-6cn1A:undetectable","3w1wA-6cn1A:undetectable;3w1wB-6cn1A:undetectable"],["3WIP_G_ACTG305_0","ACETYLCHOLINE-BINDING PROTEIN","6cn1","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","Pseudomonas putida",3,"ASP A 281;ARG A  17;LYS A 255","None","1.20A","3wipG-6cn1A:undetectable","3wipG-6cn1A:undetectable"],["4FE1_A_PQNA846_1","PHOTOSYSTEM I P700 CHLOROPHYLL A APOPROTEIN A1;PHOTOSYSTEM I REACTION CENTER SUBUNIT IX","6cn1","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","Pseudomonas putida",5,"PHE A  57;LEU A  56;GLY A  58;ALA A 136;MET A 134","None","1.48A","4fe1A-6cn1A:undetectable;4fe1J-6cn1A:undetectable","4fe1A-6cn1A:8.67;4fe1J-6cn1A:27.27"],["4FGL_C_CLQC303_1","RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE]","6cn1","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","Pseudomonas putida",4,"ASN A 317;GLY A 324;VAL A 357;ILE A 327","None","0.90A","4fglD-6cn1A:undetectable","4fglD-6cn1A:undetectable"],["4J24_A_ESTA600_1","ESTROGEN RECEPTOR BETA","6cn1","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","Pseudomonas putida",5,"LEU A  97;GLU A 170;LEU A 197;ILE A  74;LEU A  34","None;EPU A 501 ( 4.9A);None;None;None","1.14A","4j24A-6cn1A:undetectable","4j24A-6cn1A:18.36"],["4J24_B_ESTB600_1","ESTROGEN RECEPTOR BETA","6cn1","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","Pseudomonas putida",5,"LEU A  97;GLU A 170;LEU A 197;ILE A  74;LEU A  34","None;EPU A 501 ( 4.9A);None;None;None","1.10A","4j24B-6cn1A:undetectable","4j24B-6cn1A:18.36"],["4J24_C_ESTC600_1","ESTROGEN RECEPTOR BETA","6cn1","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","Pseudomonas putida",5,"LEU A  97;GLU A 170;LEU A 197;ILE A  74;LEU A  34","None;EPU A 501 ( 4.9A);None;None;None","1.14A","4j24C-6cn1A:undetectable","4j24C-6cn1A:18.36"],["4LBG_B_ADNB402_1","PROBABLE SUGAR KINASE PROTEIN","6cn1","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","Pseudomonas putida",5,"ALA A 346;ILE A 319;VAL A 247;ALA A 383;ALA A 386","None","1.07A","4lbgB-6cn1A:undetectable","4lbgB-6cn1A:15.76"],["4LNW_A_T3A501_1","THYROID HORMONE RECEPTOR ALPHA","6cn1","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","Pseudomonas putida",5,"ILE A 172;ALA A 175;ALA A 147;LEU A  99;PHE A 159","None","1.10A","4lnwA-6cn1A:undetectable","4lnwA-6cn1A:16.60"],["4LNX_A_T3A502_1","THYROID HORMONE RECEPTOR ALPHA","6cn1","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","Pseudomonas putida",5,"ILE A 172;ALA A 175;ALA A 147;LEU A  99;PHE A 159","None","1.11A","4lnxA-6cn1A:undetectable","4lnxA-6cn1A:16.60"],["4RP9_A_ASCA501_0","ASCORBATE-SPECIFIC PERMEASE IIC COMPONENT ULAA","6cn1","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","Pseudomonas putida",5,"THR A 299;GLN A 310;ASP A 372;ILE A 330;PHE A 331","None;None;None;EPU A 501 (-4.8A);EPU A 501 (-4.8A)","1.39A","4rp9A-6cn1A:undetectable","4rp9A-6cn1A:undetectable"],["4U8V_B_MIYB1103_1","MULTIDRUG EFFLUX PUMP SUBUNIT ACRB","6cn1","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","Pseudomonas putida",5,"GLY A 401;ILE A 398;ALA A 377;VAL A 380;ARG A 418","None","1.08A","4u8vB-6cn1A:undetectable","4u8vB-6cn1A:8.97"],["4U8Y_B_MIYB1102_1","MULTIDRUG EFFLUX PUMP SUBUNIT ACRB","6cn1","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","Pseudomonas putida",5,"GLY A 401;ILE A 398;ALA A 377;VAL A 380;ARG A 418","None","1.09A","4u8yB-6cn1A:undetectable","4u8yB-6cn1A:8.97"],["4ZO1_X_T3X500_1","THYROID HORMONE RECEPTOR BETA","6cn1","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","Pseudomonas putida",5,"ILE A 172;ALA A 175;ALA A 147;LEU A  99;PHE A 159","None","1.18A","4zo1X-6cn1A:undetectable","4zo1X-6cn1A:16.80"],["4ZVM_A_DM2A303_1","RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE];RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE]","6cn1","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","Pseudomonas putida",5,"GLY A 324;THR A 323;ILE A 356;GLN A 310;ILE A 314","None","1.21A","4zvmA-6cn1A:undetectable;4zvmB-6cn1A:undetectable","4zvmA-6cn1A:18.36;4zvmB-6cn1A:18.36"],["5DLV_A_5D5A930_0","ECTONUCLEOTIDE PYROPHOSPHATASE\/PHOSPHODIESTERASE FAMILY MEMBER 2","6cn1","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","Pseudomonas putida",5,"LEU A 297;THR A 238;LEU A 242;ILE A 319;PHE A 313","None","1.35A","5dlvA-6cn1A:undetectable","5dlvA-6cn1A:undetectable"],["5HS6_A_J3ZA302_1","17-BETA-HYDROXYSTEROID DEHYDROGENASE 14","6cn1","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","Pseudomonas putida",4,"HIS A 337;GLN A 310;LEU A 379;THR A 240","None","0.97A","5hs6A-6cn1A:undetectable","5hs6A-6cn1A:18.83"],["5IKR_A_ID8A601_2","PROSTAGLANDIN G\/H SYNTHASE 2","6cn1","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","Pseudomonas putida",3,"VAL A 140;LEU A 154;MET A 134","None","0.78A","5ikrA-6cn1A:undetectable","5ikrA-6cn1A:15.31"],["5KB5_A_ADNA401_1","ADENOSINE KINASE","6cn1","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","Pseudomonas putida",5,"LEU A 269;GLY A 289;GLY A 249;ALA A 274;LEU A 285","None","0.96A","5kb5A-6cn1A:undetectable","5kb5A-6cn1A:13.33"],["5LJB_A_RTLA201_1","RETINOL-BINDING PROTEIN 1","6cn1","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","Pseudomonas putida",4,"LEU A   4;LEU A 384;ILE A 236;THR A 240","None","1.03A","5ljbA-6cn1A:undetectable","5ljbA-6cn1A:undetectable"],["5UMD_A_YMZA3801_1","60S RIBOSOMAL PROTEIN L28;28S RIBOSOMAL RNA;60S RIBOSOMAL PROTEIN L4","6cn1","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","Pseudomonas putida",4,"ALA A  94;PRO A 114;VAL A  89;ASP A  49","EPU A 501 (-3.6A);None;None;None","0.90A","5umd2-6cn1A:undetectable;5umdF-6cn1A:undetectable","5umd2-6cn1A:18.07;5umdF-6cn1A:19.10"],["6AK3_B_P2EB1201_1","PROSTAGLANDIN E2 RECEPTOR EP3 SUBTYPE,SOLUBLE CYTOCHROME B562","6cn1","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","Pseudomonas putida",4,"PRO A 301;VAL A 164;GLY A 210;VAL A 194","None","1.10A","6ak3B-6cn1A:undetectable","6ak3B-6cn1A:26.44"],["6MDQ_A_TESA604_0","SERUM ALBUMIN","6cn1","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","Pseudomonas putida",4,"ALA A 175;GLY A 130;LEU A 131;ALA A 136","None","0.83A","6mdqA-6cn1A:undetectable","6mdqA-6cn1A:18.68"]]