SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6cnj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2434_1
(CHITINASE)		 6cnj NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2
(Homo
sapiens) 		4 / 6 GLU B 133
ASP B 140
PHE B 137
ARG B 207
 None
 1.48A 2a3bB-6cnjB:
undetectable		 2a3bB-6cnjB:
11.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_2
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 6cnj NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2
(Homo
sapiens) 		4 / 6 PHE B 139
ARG B 207
GLN B 142
LEU B 183
 None
 1.28A 2nyrA-6cnjB:
undetectable		 2nyrA-6cnjB:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WW7_A_ACTA303_0
(EKC/KEOPS COMPLEX
SUBUNIT BUD32)		 6cnj NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2
(Homo
sapiens) 		4 / 4 LEU B  30
VAL B  31
GLU B 157
ARG B  22
 None
 1.21A 4ww7A-6cnjB:
0.1		 4ww7A-6cnjB:
undetectable