SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6co1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EA1_A_TPFA470_1
(CYTOCHROME P450
51-LIKE RV0764C)		 6co1 TUDOR-INTERACTING
REPAIR REGULATOR
PROTEIN
(Homo
sapiens) 		4 / 8 PHE A  62
MET A  52
PHE A 160
LEU A 177
 None
 1.12A 1ea1A-6co1A:
undetectable		 1ea1A-6co1A:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZ7_A_CA4A1_2
(ANDROGEN RECEPTOR)		 6co1 TUDOR-INTERACTING
REPAIR REGULATOR
PROTEIN
(Homo
sapiens) 		4 / 6 LEU A  51
MET A 182
MET A 183
LEU A 180
 None
 1.31A 2oz7A-6co1A:
undetectable		 2oz7A-6co1A:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WUZ_A_TPFA1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE
, PUTATIVE)		 6co1 TUDOR-INTERACTING
REPAIR REGULATOR
PROTEIN
(Homo
sapiens) 		5 / 10 MET A  31
PHE A  62
ALA A 169
LEU A 147
MET A 182
 None
 1.21A 2wuzA-6co1A:
undetectable		 2wuzA-6co1A:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD392_1
(TETX2 PROTEIN)		 6co1 TUDOR-INTERACTING
REPAIR REGULATOR
PROTEIN
(Homo
sapiens) 		4 / 5 HIS A  29
SER A  27
GLN A 172
VAL A 109
 None
 1.40A 4a99D-6co1A:
undetectable		 4a99D-6co1A:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HWK_B_SFYB806_0
(SEPIAPTERIN
REDUCTASE)		 6co1 TUDOR-INTERACTING
REPAIR REGULATOR
PROTEIN
(Homo
sapiens) 		5 / 11 LEU A 192
LEU A  60
PHE A 160
GLN A 199
ALA A 195
 None
 1.31A 4hwkB-6co1A:
undetectable		 4hwkB-6co1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HWK_C_SFYC804_0
(SEPIAPTERIN
REDUCTASE)		 6co1 TUDOR-INTERACTING
REPAIR REGULATOR
PROTEIN
(Homo
sapiens) 		5 / 12 LEU A 192
LEU A  60
PHE A 160
GLN A 199
ALA A 195
 None
 1.31A 4hwkC-6co1A:
undetectable		 4hwkC-6co1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HWK_D_SFYD803_0
(SEPIAPTERIN
REDUCTASE)		 6co1 TUDOR-INTERACTING
REPAIR REGULATOR
PROTEIN
(Homo
sapiens) 		5 / 11 LEU A 192
LEU A  60
PHE A 160
GLN A 199
ALA A 195
 None
 1.33A 4hwkD-6co1A:
undetectable		 4hwkD-6co1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_2
(ANDROGEN RECEPTOR)		 6co1 TUDOR-INTERACTING
REPAIR REGULATOR
PROTEIN
(Homo
sapiens) 		4 / 6 LEU A 147
MET A  52
LEU A 173
VAL A   6
 None
 1.12A 4okbA-6co1A:
undetectable		 4okbA-6co1A:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC3_A_486A801_2
(GLUCOCORTICOID
RECEPTOR)		 6co1 TUDOR-INTERACTING
REPAIR REGULATOR
PROTEIN
(Homo
sapiens) 		4 / 5 LEU A 161
LEU A 192
MET A 183
TYR A 148
 None
 1.34A 5uc3A-6co1A:
undetectable		 5uc3A-6co1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_D_CVID301_0
(REGULATORY PROTEIN
TETR)		 6co1 TUDOR-INTERACTING
REPAIR REGULATOR
PROTEIN
(Homo
sapiens) 		5 / 12 MET A 183
MET A 182
ALA A 176
LEU A 188
PHE A 165
 None
 1.38A 5vlmD-6co1A:
undetectable		 5vlmD-6co1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_E_CVIE301_0
(REGULATORY PROTEIN
TETR)		 6co1 TUDOR-INTERACTING
REPAIR REGULATOR
PROTEIN
(Homo
sapiens) 		5 / 12 MET A 183
MET A 182
ALA A 176
LEU A 188
PHE A 165
 None
 1.42A 5vlmE-6co1A:
undetectable		 5vlmE-6co1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_H_CVIH301_0
(REGULATORY PROTEIN
TETR)		 6co1 TUDOR-INTERACTING
REPAIR REGULATOR
PROTEIN
(Homo
sapiens) 		5 / 12 MET A 183
MET A 182
ALA A 176
LEU A 188
PHE A 165
 None
 1.31A 5vlmH-6co1A:
undetectable		 5vlmH-6co1A:
undetectable