SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6co2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EA1_A_TPFA470_1
(CYTOCHROME P450
51-LIKE RV0764C)		 6co2 NUDT16-TUDOR-INTERAC
TING (NUDT16TI)
(Homo
sapiens) 		4 / 8 PHE A  57
MET A  47
PHE A 159
LEU A 176
 None
 1.21A 1ea1A-6co2A:
undetectable		 1ea1A-6co2A:
12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H9Z_A_RWFA3001_1
(SERUM ALBUMIN)		 6co2 NUDT16-TUDOR-INTERAC
TING (NUDT16TI)
(Homo
sapiens) 		5 / 11 PHE A 111
ALA A 175
LEU A 176
LEU A 172
LEU A 160
 None
 1.15A 1h9zA-6co2A:
undetectable		 1h9zA-6co2A:
8.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A8T_A_ADNA252_1
(U8 SNORNA-BINDING
PROTEIN X29)		 6co2 NUDT16-TUDOR-INTERAC
TING (NUDT16TI)
(Homo
sapiens) 		5 / 9 HIS A  24
ARG A  50
GLY A  59
ILE A 165
GLN A 171
 None
 1.11A 2a8tA-6co2A:
28.4		 2a8tA-6co2A:
53.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A8T_A_ADNA252_1
(U8 SNORNA-BINDING
PROTEIN X29)		 6co2 NUDT16-TUDOR-INTERAC
TING (NUDT16TI)
(Homo
sapiens) 		6 / 9 HIS A  24
ARG A  50
GLY A  60
PHE A  61
ILE A 165
GLN A 171
 None
 0.63A 2a8tA-6co2A:
28.4		 2a8tA-6co2A:
53.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A8T_B_ADNB252_1
(U8 SNORNA-BINDING
PROTEIN X29)		 6co2 NUDT16-TUDOR-INTERAC
TING (NUDT16TI)
(Homo
sapiens) 		5 / 8 HIS A  24
GLY A  56
PHE A  61
ILE A 165
GLN A 171
 None
 0.57A 2a8tB-6co2A:
28.6		 2a8tB-6co2A:
53.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M50_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 6co2 NUDT16-TUDOR-INTERAC
TING (NUDT16TI)
(Homo
sapiens) 		5 / 12 ASP A  63
GLN A  48
ARG A  89
ARG A  75
LEU A  77
 None
 1.03A 5m50E-6co2A:
undetectable		 5m50E-6co2A:
11.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M54_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 6co2 NUDT16-TUDOR-INTERAC
TING (NUDT16TI)
(Homo
sapiens) 		5 / 12 ASP A  63
ARG A  50
GLN A  48
ARG A  75
LEU A  77
 None
 0.98A 5m54B-6co2A:
undetectable		 5m54B-6co2A:
11.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M54_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 6co2 NUDT16-TUDOR-INTERAC
TING (NUDT16TI)
(Homo
sapiens) 		5 / 12 ASP A  63
ARG A  50
GLN A  48
ARG A  75
LEU A  77
 None
 1.04A 5m54E-6co2A:
undetectable		 5m54E-6co2A:
11.50