SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6co7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R5L_A_VIVA301_0
(PROTEIN
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN))		 6co7 PREDICTED PROTEIN
(Nematostella
vectensis) 		5 / 12 VAL A 308
ILE A 315
ILE A 392
VAL A 394
ILE A 354
 None
 1.20A 1r5lA-6co7A:
undetectable		 1r5lA-6co7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_B_HSMB402_1
(NITROPHORIN 1)		 6co7 PREDICTED PROTEIN
(Nematostella
vectensis) 		4 / 5 GLU A 660
THR A 665
LEU A 666
LEU A 662
 None
 1.23A 1u18B-6co7A:
undetectable		 1u18B-6co7A:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_A_SAMA1001_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 6co7 PREDICTED PROTEIN
(Nematostella
vectensis) 		5 / 12 PHE A 336
TYR A 338
ALA A 331
GLY A 326
GLY A 328
 None
 1.16A 2igtA-6co7A:
2.5		 2igtA-6co7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_F_SNLF6001_2
(MINERALOCORTICOID
RECEPTOR)		 6co7 PREDICTED PROTEIN
(Nematostella
vectensis) 		4 / 5 LEU A 616
LEU A 589
LEU A 491
MET A 519
 None
 1.11A 2oaxF-6co7A:
undetectable		 2oaxF-6co7A:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_D_ASDD1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 6co7 PREDICTED PROTEIN
(Nematostella
vectensis) 		5 / 9 PHE A 644
LEU A 581
ALA A 587
LEU A 585
ALA A 613
 None
 1.08A 2vcvD-6co7A:
undetectable		 2vcvD-6co7A:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_E_ASDE1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 6co7 PREDICTED PROTEIN
(Nematostella
vectensis) 		5 / 9 PHE A 644
LEU A 581
ALA A 587
LEU A 585
ALA A 613
 None
 1.05A 2vcvE-6co7A:
undetectable		 2vcvE-6co7A:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_H_ASDH1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 6co7 PREDICTED PROTEIN
(Nematostella
vectensis) 		5 / 9 PHE A 644
LEU A 581
ALA A 587
LEU A 585
ALA A 613
 None
 1.08A 2vcvH-6co7A:
undetectable		 2vcvH-6co7A:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_I_ASDI1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 6co7 PREDICTED PROTEIN
(Nematostella
vectensis) 		5 / 9 PHE A 644
LEU A 581
ALA A 587
LEU A 585
ALA A 613
 None
 1.07A 2vcvI-6co7A:
2.1		 2vcvI-6co7A:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y05_A_RALA801_1
(PROSTAGLANDIN
REDUCTASE 1)		 6co7 PREDICTED PROTEIN
(Nematostella
vectensis) 		4 / 8 TYR A1111
VAL A1108
ARG A1104
VAL A 967
 None
None
None
POV  A3002 ( 4.7A)
 1.23A 2y05A-6co7A:
3.0
2y05B-6co7A:
3.1		 2y05A-6co7A:
13.58
2y05B-6co7A:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX9_B_SALB1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 6co7 PREDICTED PROTEIN
(Nematostella
vectensis) 		4 / 8 GLU A1165
LEU A 666
THR A 678
ALA A 608
 None
 0.87A 3ax9B-6co7A:
undetectable		 3ax9B-6co7A:
4.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_A_SAMA300_0
(PUTATIVE RRNA
METHYLASE)		 6co7 PREDICTED PROTEIN
(Nematostella
vectensis) 		5 / 12 ASP A 220
ILE A 214
GLY A 243
HIS A 241
LEU A 255
 None
 1.14A 3eeyA-6co7A:
2.7		 3eeyA-6co7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_B_SAMB300_0
(PUTATIVE RRNA
METHYLASE)		 6co7 PREDICTED PROTEIN
(Nematostella
vectensis) 		5 / 12 ASP A 220
ILE A 214
GLY A 243
HIS A 241
LEU A 255
 None
 1.16A 3eeyB-6co7A:
2.5		 3eeyB-6co7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_C_SAMC300_0
(PUTATIVE RRNA
METHYLASE)		 6co7 PREDICTED PROTEIN
(Nematostella
vectensis) 		5 / 12 ASP A 220
ILE A 214
GLY A 243
HIS A 241
LEU A 255
 None
 1.16A 3eeyC-6co7A:
2.9		 3eeyC-6co7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_D_SAMD300_0
(PUTATIVE RRNA
METHYLASE)		 6co7 PREDICTED PROTEIN
(Nematostella
vectensis) 		5 / 12 ASP A 220
ILE A 214
GLY A 243
HIS A 241
LEU A 255
 None
 1.14A 3eeyD-6co7A:
2.8		 3eeyD-6co7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_E_SAME300_0
(PUTATIVE RRNA
METHYLASE)		 6co7 PREDICTED PROTEIN
(Nematostella
vectensis) 		5 / 12 ASP A 220
ILE A 214
GLY A 243
HIS A 241
LEU A 255
 None
 1.18A 3eeyE-6co7A:
2.3		 3eeyE-6co7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_J_SAMJ300_0
(PUTATIVE RRNA
METHYLASE)		 6co7 PREDICTED PROTEIN
(Nematostella
vectensis) 		5 / 12 ASP A 220
ILE A 214
GLY A 243
HIS A 241
LEU A 255
 None
 1.18A 3eeyJ-6co7A:
undetectable		 3eeyJ-6co7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EIG_A_MTXA200_2
(DIHYDROFOLATE
REDUCTASE)		 6co7 PREDICTED PROTEIN
(Nematostella
vectensis) 		4 / 5 ASP A 119
ILE A 274
VAL A 256
THR A  92
 None
 1.25A 3eigA-6co7A:
1.4		 3eigA-6co7A:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LW5_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6co7 PREDICTED PROTEIN
(Nematostella
vectensis) 		5 / 10 ILE A 526
SER A 635
ALA A 641
LEU A 617
ALA A 621
 None
 1.27A 3lw5B-6co7A:
2.9		 3lw5B-6co7A:
6.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RET_A_SALA201_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 6co7 PREDICTED PROTEIN
(Nematostella
vectensis) 		5 / 10 ALA A 330
VAL A 308
MET A 311
ILE A 382
ILE A 392
 None
 1.08A 3retA-6co7A:
undetectable
3retB-6co7A:
undetectable		 3retA-6co7A:
17.00
3retB-6co7A:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_A_AERA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 6co7 PREDICTED PROTEIN
(Nematostella
vectensis) 		5 / 12 ALA A 190
TYR A 395
ILE A 324
LEU A 301
VAL A 142
 None
 1.01A 3rukA-6co7A:
undetectable		 3rukA-6co7A:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SGL_A_SAMA692_0
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)		 6co7 PREDICTED PROTEIN
(Nematostella
vectensis) 		5 / 12 GLY A 328
LEU A 301
VAL A 367
GLY A 335
PHE A 336
 None
 1.09A 3sglA-6co7A:
2.1		 3sglA-6co7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_B_SALB1345_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 6co7 PREDICTED PROTEIN
(Nematostella
vectensis) 		4 / 8 GLU A1165
LEU A 666
THR A 678
ALA A 608
 None
 0.85A 3uniB-6co7A:
undetectable		 3uniB-6co7A:
4.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_D_VIVD301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 6co7 PREDICTED PROTEIN
(Nematostella
vectensis) 		5 / 12 VAL A 308
ILE A 315
ILE A 392
VAL A 394
ILE A 354
 None
 1.07A 3w67D-6co7A:
undetectable		 3w67D-6co7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		 6co7 PREDICTED PROTEIN
(Nematostella
vectensis) 		5 / 10 GLN A 446
PHE A 442
LEU A 453
THR A 449
THR A 452
 None
 1.40A 3zncA-6co7A:
undetectable		 3zncA-6co7A:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R1Z_A_AERA601_1
(CYP17A1 PROTEIN)		 6co7 PREDICTED PROTEIN
(Nematostella
vectensis) 		5 / 9 ALA A 190
TYR A 395
ILE A 324
GLY A 162
VAL A 142
 None
 1.11A 4r1zA-6co7A:
undetectable		 4r1zA-6co7A:
11.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTB_A_SAMA501_1
(HYDG PROTEIN)		 6co7 PREDICTED PROTEIN
(Nematostella
vectensis) 		3 / 3 GLU A 601
ARG A 597
GLN A 474
 None
 0.90A 4rtbA-6co7A:
undetectable		 4rtbA-6co7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_A_377A402_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 6co7 PREDICTED PROTEIN
(Nematostella
vectensis) 		5 / 9 ALA A 608
ALA A 679
SER A 688
ALA A 610
SER A 614
 None
 1.04A 4twdA-6co7A:
3.2
4twdB-6co7A:
3.9
4twdC-6co7A:
3.1
4twdD-6co7A:
2.3
4twdE-6co7A:
3.1		 4twdA-6co7A:
11.73
4twdB-6co7A:
11.73
4twdC-6co7A:
11.73
4twdD-6co7A:
11.73
4twdE-6co7A:
11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WOZ_B_MN9B401_0
(N-ACETYLNEURAMINATE
LYASE)		 6co7 PREDICTED PROTEIN
(Nematostella
vectensis) 		4 / 6 SER A 484
LEU A 485
ASP A 486
LEU A 576
 None
 0.63A 4wozA-6co7A:
undetectable
4wozB-6co7A:
undetectable		 4wozA-6co7A:
undetectable
4wozB-6co7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIK_A_SAMA301_0
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 6co7 PREDICTED PROTEIN
(Nematostella
vectensis) 		5 / 12 GLY A 265
GLY A 213
ARG A 113
GLY A 269
HIS A 116
 None
 1.01A 5hikA-6co7A:
undetectable		 5hikA-6co7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW4_A_SAMA302_1
(PUTATIVE
O-METHYLTRANSFERASE
YRRM)		 6co7 PREDICTED PROTEIN
(Nematostella
vectensis) 		4 / 6 SER A 910
ARG A 623
ARG A 619
ASP A 627
 None
 1.25A 5zw4A-6co7A:
undetectable		 5zw4A-6co7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HUO_D_08HD501_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT GAMMA-2)		 6co7 PREDICTED PROTEIN
(Nematostella
vectensis) 		4 / 8 TYR A 834
PHE A 734
VAL A 718
SER A 839
 None
 1.23A 6huoC-6co7A:
3.4
6huoD-6co7A:
3.1		 6huoC-6co7A:
20.00
6huoD-6co7A:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_A_AM2A301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 6co7 PREDICTED PROTEIN
(Nematostella
vectensis) 		4 / 8 ASP A 672
GLU A 605
ASP A1162
GLU A1159
 None
 1.21A 6mn4A-6co7A:
undetectable		 6mn4A-6co7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_B_AM2B301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 6co7 PREDICTED PROTEIN
(Nematostella
vectensis) 		4 / 8 ASP A 672
GLU A 605
ASP A1162
GLU A1159
 None
 1.12A 6mn4B-6co7A:
undetectable		 6mn4B-6co7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_E_LLLE301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 6co7 PREDICTED PROTEIN
(Nematostella
vectensis) 		4 / 7 ASP A 672
GLU A 605
ASP A1162
GLU A1159
 None
 1.21A 6mn5E-6co7A:
undetectable		 6mn5E-6co7A:
15.48