SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6coy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D8C_A_SORA4000_0
(MALATE SYNTHASE G)		 6coy CHLORIDE CHANNEL
PROTEIN 1
(Homo
sapiens) 		3 / 3 GLN A 571
HIS A 538
PRO A 575
 None
 0.64A 1d8cA-6coyA:
undetectable		 1d8cA-6coyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ9_A_CAMA503_0
(CYTOCHROME P450-CAM)		 6coy CHLORIDE CHANNEL
PROTEIN 1
(Homo
sapiens) 		4 / 8 THR A 539
VAL A 544
THR A 281
VAL A 275
 None
 1.10A 1dz9A-6coyA:
undetectable		 1dz9A-6coyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1502_0
(FERROCHELATASE)		 6coy CHLORIDE CHANNEL
PROTEIN 1
(Homo
sapiens) 		4 / 8 PRO A 420
VAL A 229
GLY A 230
MET A 485
 None
None
CL  A1001 (-3.2A)
None
 0.92A 1hrkA-6coyA:
undetectable		 1hrkA-6coyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2502_0
(FERROCHELATASE)		 6coy CHLORIDE CHANNEL
PROTEIN 1
(Homo
sapiens) 		4 / 8 PRO A 420
VAL A 229
GLY A 230
MET A 485
 None
None
CL  A1001 (-3.2A)
None
 0.92A 1hrkB-6coyA:
undetectable		 1hrkB-6coyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_L_AG2L7014_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 6coy CHLORIDE CHANNEL
PROTEIN 1
(Homo
sapiens) 		4 / 7 LEU A 143
LEU A 171
ILE A 227
MET A 419
 None
 0.96A 1n13I-6coyA:
undetectable
1n13L-6coyA:
undetectable		 1n13I-6coyA:
17.14
1n13L-6coyA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O76_B_CAMB1420_0
(CYTOCHROME P450-CAM)		 6coy CHLORIDE CHANNEL
PROTEIN 1
(Homo
sapiens) 		4 / 8 THR A 539
VAL A 544
THR A 281
VAL A 275
 None
 1.09A 1o76B-6coyA:
undetectable		 1o76B-6coyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_J_FUAJ711_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6coy CHLORIDE CHANNEL
PROTEIN 1
(Homo
sapiens) 		5 / 11 THR A 539
SER A 537
TYR A 578
SER A 541
PHE A 279
 None
 1.39A 1q23J-6coyA:
undetectable		 1q23J-6coyA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOF_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 6coy CHLORIDE CHANNEL
PROTEIN 1
(Homo
sapiens) 		4 / 5 LEU A 173
PRO A 478
ALA A 176
ILE A 172
 None
 0.95A 2aofB-6coyA:
undetectable		 2aofB-6coyA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_B_SAMB201_0
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 6coy CHLORIDE CHANNEL
PROTEIN 1
(Homo
sapiens) 		5 / 12 GLY A 528
ALA A 525
GLY A 523
LEU A 427
LEU A 361
 None
 1.02A 2nyuB-6coyA:
undetectable		 2nyuB-6coyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_A_CHDA502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 6coy CHLORIDE CHANNEL
PROTEIN 1
(Homo
sapiens) 		4 / 8 PRO A 420
VAL A 229
GLY A 230
MET A 485
 None
None
CL  A1001 (-3.2A)
None
 0.99A 2po5A-6coyA:
undetectable		 2po5A-6coyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_A_CHDA502_0
(FERROCHELATASE)		 6coy CHLORIDE CHANNEL
PROTEIN 1
(Homo
sapiens) 		4 / 8 PRO A 420
VAL A 229
GLY A 230
MET A 485
 None
None
CL  A1001 (-3.2A)
None
 0.96A 2qd3A-6coyA:
undetectable		 2qd3A-6coyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_B_CHDB504_0
(FERROCHELATASE)		 6coy CHLORIDE CHANNEL
PROTEIN 1
(Homo
sapiens) 		4 / 6 ILE A 424
ARG A 421
PRO A 234
SER A 189
 None
None
None
CL  A1002 (-2.5A)
 1.32A 2qd3B-6coyA:
undetectable		 2qd3B-6coyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_A_AG2A672_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 6coy CHLORIDE CHANNEL
PROTEIN 1
(Homo
sapiens) 		4 / 7 LEU A 143
LEU A 171
ILE A 227
MET A 419
 None
 0.94A 2qqcA-6coyA:
undetectable
2qqcF-6coyA:
undetectable		 2qqcA-6coyA:
15.71
2qqcF-6coyA:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_I_AG2I671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 6coy CHLORIDE CHANNEL
PROTEIN 1
(Homo
sapiens) 		4 / 7 LEU A 143
LEU A 171
ILE A 227
MET A 419
 None
 0.97A 2qqcG-6coyA:
undetectable
2qqcJ-6coyA:
undetectable		 2qqcG-6coyA:
15.71
2qqcJ-6coyA:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQD_A_AG2A671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 6coy CHLORIDE CHANNEL
PROTEIN 1
(Homo
sapiens) 		4 / 7 LEU A 143
LEU A 171
ILE A 227
MET A 419
 None
 0.86A 2qqdA-6coyA:
undetectable
2qqdE-6coyA:
undetectable		 2qqdA-6coyA:
15.71
2qqdE-6coyA:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 6coy CHLORIDE CHANNEL
PROTEIN 1
(Homo
sapiens) 		4 / 6 ILE A 354
THR A 533
PHE A 488
PHE A 428
 None
 1.32A 3elzB-6coyA:
undetectable		 3elzB-6coyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GSS_A_EAAA212_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 6coy CHLORIDE CHANNEL
PROTEIN 1
(Homo
sapiens) 		4 / 7 VAL A 544
ILE A 290
THR A 268
GLY A 284
 None
 0.75A 3gssA-6coyA:
undetectable		 3gssA-6coyA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GSS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 6coy CHLORIDE CHANNEL
PROTEIN 1
(Homo
sapiens) 		4 / 7 VAL A 544
ILE A 290
THR A 268
GLY A 284
 None
 0.79A 3gssB-6coyA:
undetectable		 3gssB-6coyA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		 6coy CHLORIDE CHANNEL
PROTEIN 1
(Homo
sapiens) 		5 / 12 GLY A 226
GLY A 230
ALA A 221
ALA A 218
CYH A 179
 None
CL  A1001 (-3.2A)
None
None
None
 1.12A 3keeA-6coyA:
undetectable		 3keeA-6coyA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_A_DXCA91_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 6coy CHLORIDE CHANNEL
PROTEIN 1
(Homo
sapiens) 		3 / 3 PHE A 428
GLN A 445
PHE A 488
 None
 0.79A 3rv5A-6coyA:
undetectable		 3rv5A-6coyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_A_CLMA221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6coy CHLORIDE CHANNEL
PROTEIN 1
(Homo
sapiens) 		5 / 9 THR A 539
SER A 537
TYR A 578
SER A 541
PHE A 279
 None
 1.37A 3u9fA-6coyA:
undetectable		 3u9fA-6coyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_B_CLMB221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6coy CHLORIDE CHANNEL
PROTEIN 1
(Homo
sapiens) 		5 / 12 THR A 539
SER A 537
TYR A 578
SER A 541
PHE A 279
 None
 1.36A 3u9fB-6coyA:
undetectable
3u9fC-6coyA:
undetectable		 3u9fB-6coyA:
undetectable
3u9fC-6coyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_C_CLMC221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6coy CHLORIDE CHANNEL
PROTEIN 1
(Homo
sapiens) 		5 / 11 THR A 539
SER A 537
TYR A 578
SER A 541
PHE A 279
 None
 1.36A 3u9fA-6coyA:
undetectable
3u9fC-6coyA:
undetectable		 3u9fA-6coyA:
undetectable
3u9fC-6coyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_D_CLMD221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6coy CHLORIDE CHANNEL
PROTEIN 1
(Homo
sapiens) 		5 / 12 THR A 539
SER A 537
TYR A 578
SER A 541
PHE A 279
 None
 1.35A 3u9fD-6coyA:
undetectable
3u9fE-6coyA:
undetectable		 3u9fD-6coyA:
undetectable
3u9fE-6coyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_E_CLME221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6coy CHLORIDE CHANNEL
PROTEIN 1
(Homo
sapiens) 		5 / 10 THR A 539
SER A 537
TYR A 578
SER A 541
PHE A 279
 None
 1.31A 3u9fE-6coyA:
undetectable		 3u9fE-6coyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_F_CLMF221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6coy CHLORIDE CHANNEL
PROTEIN 1
(Homo
sapiens) 		5 / 10 THR A 539
SER A 537
TYR A 578
SER A 541
PHE A 279
 None
 1.36A 3u9fD-6coyA:
undetectable
3u9fF-6coyA:
undetectable		 3u9fD-6coyA:
undetectable
3u9fF-6coyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_G_CLMG221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6coy CHLORIDE CHANNEL
PROTEIN 1
(Homo
sapiens) 		5 / 12 THR A 539
SER A 537
TYR A 578
SER A 541
PHE A 279
 None
 1.36A 3u9fG-6coyA:
undetectable
3u9fH-6coyA:
undetectable		 3u9fG-6coyA:
undetectable
3u9fH-6coyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_I_CLMI221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6coy CHLORIDE CHANNEL
PROTEIN 1
(Homo
sapiens) 		5 / 10 THR A 539
SER A 537
TYR A 578
SER A 541
PHE A 279
 None
 1.40A 3u9fI-6coyA:
undetectable		 3u9fI-6coyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_J_CLMJ221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6coy CHLORIDE CHANNEL
PROTEIN 1
(Homo
sapiens) 		5 / 12 THR A 539
SER A 537
TYR A 578
SER A 541
PHE A 279
 None
 1.32A 3u9fJ-6coyA:
undetectable
3u9fK-6coyA:
undetectable		 3u9fJ-6coyA:
undetectable
3u9fK-6coyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_K_CLMK221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6coy CHLORIDE CHANNEL
PROTEIN 1
(Homo
sapiens) 		5 / 10 THR A 539
SER A 537
TYR A 578
SER A 541
PHE A 279
 None
 1.36A 3u9fK-6coyA:
undetectable		 3u9fK-6coyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_L_CLML221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6coy CHLORIDE CHANNEL
PROTEIN 1
(Homo
sapiens) 		5 / 12 THR A 539
SER A 537
TYR A 578
SER A 541
PHE A 279
 None
 1.42A 3u9fJ-6coyA:
undetectable
3u9fL-6coyA:
undetectable		 3u9fJ-6coyA:
undetectable
3u9fL-6coyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_N_CLMN221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6coy CHLORIDE CHANNEL
PROTEIN 1
(Homo
sapiens) 		5 / 11 THR A 539
SER A 537
TYR A 578
SER A 541
PHE A 279
 None
 1.35A 3u9fN-6coyA:
undetectable
3u9fO-6coyA:
undetectable		 3u9fN-6coyA:
undetectable
3u9fO-6coyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_O_CLMO221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6coy CHLORIDE CHANNEL
PROTEIN 1
(Homo
sapiens) 		5 / 11 THR A 539
SER A 537
TYR A 578
SER A 541
PHE A 279
 None
 1.36A 3u9fM-6coyA:
undetectable
3u9fO-6coyA:
undetectable		 3u9fM-6coyA:
undetectable
3u9fO-6coyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_P_CLMP221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6coy CHLORIDE CHANNEL
PROTEIN 1
(Homo
sapiens) 		5 / 9 THR A 539
SER A 537
TYR A 578
SER A 541
PHE A 279
 None
 1.39A 3u9fP-6coyA:
undetectable		 3u9fP-6coyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_S_CLMS221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6coy CHLORIDE CHANNEL
PROTEIN 1
(Homo
sapiens) 		5 / 12 THR A 539
SER A 537
TYR A 578
SER A 541
PHE A 279
 None
 1.36A 3u9fP-6coyA:
undetectable
3u9fS-6coyA:
undetectable		 3u9fP-6coyA:
undetectable
3u9fS-6coyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ6_A_SAMA300_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 6coy CHLORIDE CHANNEL
PROTEIN 1
(Homo
sapiens) 		5 / 12 LEU A 207
ILE A 238
GLY A 270
ILE A 266
LEU A 198
 None
 1.02A 3uj6A-6coyA:
undetectable		 3uj6A-6coyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_C_NOVC2000_1
(DNA GYRASE SUBUNIT B)		 6coy CHLORIDE CHANNEL
PROTEIN 1
(Homo
sapiens) 		5 / 12 ILE A 479
PRO A 478
ALA A 176
ILE A 172
SER A 225
 None
 1.08A 4uroC-6coyA:
undetectable		 4uroC-6coyA:
12.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJQ_D_ERYD1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 6coy CHLORIDE CHANNEL
PROTEIN 1
(Homo
sapiens) 		5 / 12 SER A 541
THR A 539
SER A 576
MET A 373
GLU A 232
 None
 1.44A 4zjqD-6coyA:
2.6		 4zjqD-6coyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ENT_C_MIYC901_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT
ACRB,MULTIDRUG
EFFLUX PUMP SUBUNIT
ACRB)		 6coy CHLORIDE CHANNEL
PROTEIN 1
(Homo
sapiens) 		5 / 9 SER A 175
GLY A 233
SER A 189
ILE A 238
ALA A 239
 None
CL  A1001 (-4.6A)
CL  A1002 (-2.5A)
None
None
 1.42A 5entC-6coyA:
undetectable		 5entC-6coyA:
9.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_B_9SCB601_1
(SERUM ALBUMIN)		 6coy CHLORIDE CHANNEL
PROTEIN 1
(Homo
sapiens) 		4 / 6 CYH A 277
PHE A 279
LEU A 219
SER A 139
 None
 1.42A 6a7pB-6coyA:
undetectable		 6a7pB-6coyA:
undetectable