SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6cp0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_A_URFA1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)
6cp0 -
(-)
4 / 6 ILE A 345
SER A 438
ASN A  43
THR A  44
None
1.19A 1h7xA-6cp0A:
undetectable
1h7xA-6cp0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_B_URFB1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)
6cp0 -
(-)
4 / 6 ILE A 345
SER A 438
ASN A  43
THR A  44
None
1.20A 1h7xB-6cp0A:
undetectable
1h7xB-6cp0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_C_URFC1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)
6cp0 -
(-)
4 / 6 ILE A 345
SER A 438
ASN A  43
THR A  44
None
1.19A 1h7xC-6cp0A:
undetectable
1h7xC-6cp0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_D_URFD1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)
6cp0 -
(-)
4 / 6 ILE A 345
SER A 438
ASN A  43
THR A  44
None
1.20A 1h7xD-6cp0A:
undetectable
1h7xD-6cp0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PNL_B_PACB559_0
(PENICILLIN
AMIDOHYDROLASE)
6cp0 -
(-)
4 / 8 PHE A 445
SER A 457
ALA A 447
ASN A 154
None
1.05A 1pnlA-6cp0A:
undetectable
1pnlB-6cp0A:
2.1
1pnlA-6cp0A:
undetectable
1pnlB-6cp0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_C_H4BC1002_1
(HYPOTHETICAL PROTEIN
PH0634)
6cp0 -
(-)
4 / 6 ASP A 172
PHE A 171
THR A  47
GLU A 443
None
1.43A 2dttB-6cp0A:
0.7
2dttC-6cp0A:
undetectable
2dttB-6cp0A:
undetectable
2dttC-6cp0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AMU_A_AG2A422_1
(PUTATIVE
UNCHARACTERIZED
PROTEIN)
6cp0 -
(-)
4 / 5 GLU A  12
ASN A 502
VAL A 504
ARG A 106
None
1.36A 3amuA-6cp0A:
undetectable
3amuA-6cp0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR4_X_PNTX101_0
(PROTEIN S100-B)
6cp0 -
(-)
3 / 3 CYH A 464
HIS A 465
PHE A 456
None
1.22A 3cr4X-6cp0A:
1.2
3cr4X-6cp0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_D_NCTD501_1
(CYTOCHROME P450 2A6)
6cp0 -
(-)
4 / 7 GLY A 144
ILE A 130
LEU A 120
PHE A  55
None
0.66A 4ejjD-6cp0A:
undetectable
4ejjD-6cp0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K17_B_OHBB701_0
(LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A)
6cp0 -
(-)
4 / 5 GLU A  38
SER A 457
ARG A 431
PRO A 449
None
1.42A 4k17B-6cp0A:
undetectable
4k17B-6cp0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WW7_A_ACTA305_0
(EKC/KEOPS COMPLEX
SUBUNIT BUD32)
6cp0 -
(-)
4 / 6 LEU A 412
GLU A 415
ASN A 404
ILE A 403
None
0.98A 4ww7A-6cp0A:
undetectable
4ww7A-6cp0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Y_BEZY801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)
6cp0 -
(-)
4 / 5 PHE A 372
ILE A 354
GLY A 369
ILE A 403
None
0.78A 5dzkd-6cp0A:
undetectable
5dzkk-6cp0A:
undetectable
5dzky-6cp0A:
undetectable
5dzkd-6cp0A:
undetectable
5dzkk-6cp0A:
undetectable
5dzky-6cp0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MXB_A_ML1A220_1
(CLASS 10 PLANT
PATHOGENESIS-RELATED
PROTEIN)
6cp0 -
(-)
5 / 9 LEU A 120
VAL A 119
LEU A 483
TYR A 478
THR A 474
None
1.42A 5mxbA-6cp0A:
undetectable
5mxbA-6cp0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_A_8NUA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)
6cp0 -
(-)
5 / 12 SER A 152
ILE A 149
PHE A 445
PHE A 456
LEU A 498
None
1.44A 6a93A-6cp0A:
2.4
6a93A-6cp0A:
undetectable