SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6cp2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OMB_A_IPHA2001_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 6cp2 -
(-) 		4 / 5 PRO B  45
TYR B 129
TYR B  75
PRO B  77
 None
 1.18A 2ombA-6cp2B:
undetectable
2ombB-6cp2B:
undetectable		 2ombA-6cp2B:
undetectable
2ombB-6cp2B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OMB_D_IPHD2002_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 6cp2 -
(-) 		4 / 7 PRO B  45
TYR B  75
HIS B  76
PRO B  77
 None
 0.91A 2ombC-6cp2B:
undetectable
2ombD-6cp2B:
undetectable		 2ombC-6cp2B:
undetectable
2ombD-6cp2B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OMB_D_IPHD2002_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 6cp2 -
(-) 		4 / 7 TYR B  75
HIS B  76
PRO B  77
PRO B  45
 None
 0.79A 2ombC-6cp2B:
undetectable
2ombD-6cp2B:
undetectable		 2ombC-6cp2B:
undetectable
2ombD-6cp2B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OMB_D_IPHD2002_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 6cp2 -
(-) 		4 / 7 TYR B  75
PRO B  77
PRO B  45
TYR B 129
 None
 1.24A 2ombC-6cp2B:
undetectable
2ombD-6cp2B:
undetectable		 2ombC-6cp2B:
undetectable
2ombD-6cp2B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZGW_B_ADNB1302_1
(BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 6cp2 -
(-) 		4 / 6 GLU B 118
ALA B 123
PRO B 117
ALA B 126
 None
 1.19A 2zgwB-6cp2B:
undetectable		 2zgwB-6cp2B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_A_AERA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 6cp2 -
(-) 		5 / 12 PHE B  70
ILE B 105
LEU B 108
ALA B  50
VAL B 112
 None
 1.07A 3rukA-6cp2B:
undetectable		 3rukA-6cp2B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_E_ZPCE1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 6cp2 -
(-) 		4 / 6 GLU B 128
TYR B  75
VAL B 112
PHE B 136
 None
 1.17A 4a97E-6cp2B:
undetectable		 4a97E-6cp2B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		 6cp2 -
(-) 		4 / 6 ASN B  43
PRO B 115
ASP B  47
TYR B  46
 None
 1.06A 5umd2-6cp2B:
undetectable
5umdF-6cp2B:
undetectable		 5umd2-6cp2B:
undetectable
5umdF-6cp2B:
undetectable