SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6cp7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_B_SAMB1293_1
(GLYCINE
N-METHYLTRANSFERASE)		 6cp7 ATP SYNTHASE SUBUNIT
A
(Saccharomyces
cerevisiae) 		4 / 5 ASP X 244
SER X 240
ASN X 129
SER X 165
 None
 1.18A 1kiaB-6cp7X:
undetectable		 1kiaB-6cp7X:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_SAMC2293_1
(GLYCINE
N-METHYLTRANSFERASE)		 6cp7 ATP SYNTHASE SUBUNIT
A
(Saccharomyces
cerevisiae) 		4 / 6 ASP X 244
SER X 240
ASN X 129
SER X 165
 None
 1.17A 1kiaC-6cp7X:
undetectable		 1kiaC-6cp7X:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WLK_B_SPMB1302_1
(ATP-SENSITIVE INWARD
RECTIFIER POTASSIUM
CHANNEL 10)		 6cp7 ATP SYNTHASE SUBUNIT
F, MITOCHONDRIAL
(Saccharomyces
cerevisiae) 		4 / 4 ALA U  53
TYR U  55
ALA U  49
TYR U  51
 None
 1.29A 2wlkA-6cp7U:
undetectable
2wlkB-6cp7U:
undetectable		 2wlkA-6cp7U:
15.98
2wlkB-6cp7U:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A83_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 6cp7 ATP SYNTHASE SUBUNIT
A
(Saccharomyces
cerevisiae) 		5 / 12 PHE X  90
PHE X  93
LEU X 101
ALA X  64
SER X  61
 None
 1.39A 4a83A-6cp7X:
undetectable		 4a83A-6cp7X:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 6cp7 ATP SYNTHASE SUBUNIT
A
(Saccharomyces
cerevisiae) 		5 / 12 PHE X  90
PHE X  93
LEU X 101
ALA X  64
SER X  61
 None
 1.39A 4a84A-6cp7X:
undetectable		 4a84A-6cp7X:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_4_BEZ4801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 6cp7 ATP SYNTHASE SUBUNIT
F, MITOCHONDRIAL
ATP SYNTHASE SUBUNIT
A
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		4 / 5 LEU X  38
PHE U  69
ILE X  35
ILE U  73
 None
 1.06A 5dzk4-6cp7X:
undetectable
5dzkg-6cp7X:
undetectable
5dzkm-6cp7X:
undetectable
5dzkn-6cp7X:
undetectable		 5dzk4-6cp7X:
undetectable
5dzkg-6cp7X:
undetectable
5dzkm-6cp7X:
undetectable
5dzkn-6cp7X:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_B_AG2B501_1
(ARGININE/AGMATINE
ANTIPORTER)		 6cp7 ATP SYNTHASE SUBUNIT
A
(Saccharomyces
cerevisiae) 		4 / 6 ILE X 171
GLY X 128
ILE X 123
TRP X 126
 None
 0.96A 5j4nB-6cp7X:
0.7		 5j4nB-6cp7X:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LRB_A_ACRA1003_1
(ALPHA-1,4 GLUCAN
PHOSPHORYLASE)		 6cp7 ATP SYNTHASE SUBUNIT
A
ATP SYNTHASE SUBUNIT
F, MITOCHONDRIAL
(Saccharomyces
cerevisiae) 		4 / 6 PHE X  29
THR X  33
TYR X  32
PHE U  84
 None
 1.27A 5lrbA-6cp7X:
undetectable		 5lrbA-6cp7X:
6.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LRB_B_ACRB1003_1
(ALPHA-1,4 GLUCAN
PHOSPHORYLASE)		 6cp7 ATP SYNTHASE SUBUNIT
A
ATP SYNTHASE SUBUNIT
F, MITOCHONDRIAL
(Saccharomyces
cerevisiae) 		5 / 9 PHE X  29
THR X  33
TYR X  32
TYR U  83
PHE U  84
 None
 1.35A 5lrbB-6cp7X:
1.4		 5lrbB-6cp7X:
6.98