SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6cph'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L2I_B_CCSB417_0
(ESTROGEN RECEPTOR)		 6cph TCR BETA CHAIN
(Homo
sapiens) 		4 / 6 PRO E 139
PHE E 230
GLU E 172
GLN E 249
 None
 1.00A 1l2iB-6cphE:
undetectable		 1l2iB-6cphE:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_B_PM6B301_1
(THIOPURINE
S-METHYLTRANSFERASE)		 6cph TCR BETA CHAIN
(Homo
sapiens) 		4 / 8 GLY E 232
VAL E 136
LEU E 130
PRO E 168
 None
 1.14A 3bgdB-6cphE:
undetectable		 3bgdB-6cphE:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_C_SAMC301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 6cph TCR BETA CHAIN
(Homo
sapiens) 		5 / 12 PHE E  56
ARG E  80
PRO E  81
THR E  88
ASP E  73
 None
 1.34A 3iv6C-6cphE:
undetectable		 3iv6C-6cphE:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_C_SAMC301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 6cph TCR BETA CHAIN
(Homo
sapiens) 		5 / 12 PHE E  56
ARG E  80
PRO E  81
THR E  88
ASP E  74
 None
 1.22A 3iv6C-6cphE:
undetectable		 3iv6C-6cphE:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 6cph TCR BETA CHAIN
(Homo
sapiens) 		4 / 6 TYR E 167
LEU E 130
VAL E  12
ASP E 169
 None
 1.13A 3wrhE-6cphE:
undetectable		 3wrhE-6cphE:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 6cph TCR BETA CHAIN
(Homo
sapiens) 		4 / 6 TYR E 167
LEU E 130
VAL E  12
ASP E 169
 None
 1.05A 4ek1A-6cphE:
undetectable		 4ek1A-6cphE:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 6cph TCR BETA CHAIN
(Homo
sapiens) 		4 / 6 TYR E 167
LEU E 130
VAL E  12
ASP E 169
 None
 1.15A 4g3rA-6cphE:
undetectable		 4g3rA-6cphE:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 6cph TCR BETA CHAIN
(Homo
sapiens) 		4 / 6 TYR E 167
LEU E 130
VAL E  12
ASP E 169
 None
 1.11A 4l4cA-6cphE:
undetectable		 4l4cA-6cphE:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4E_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 6cph TCR BETA CHAIN
(Homo
sapiens) 		4 / 8 TYR E 167
LEU E 130
VAL E  12
ASP E 169
 None
 1.15A 4l4eA-6cphE:
undetectable		 4l4eA-6cphE:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_A_NPSA601_1
(SERUM ALBUMIN)		 6cph TCR BETA CHAIN
(Homo
sapiens) 		5 / 11 PHE E 230
TYR E 204
VAL E  12
GLY E 232
LEU E 130
 None
 1.24A 4or0A-6cphE:
undetectable		 4or0A-6cphE:
9.81