SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6cpy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OPJ_B_STIB4_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)
6cpy GRMZM2G135359
PSEUDOKINASE

(Zea
mays)
4 / 6 VAL A 480
ILE A 338
MET A 329
ARG A 464
None
1.11A 1opjB-6cpyA:
11.8
1opjB-6cpyA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T46_A_STIA3_2
(HOMO SAPIENS V-KIT
HARDY-ZUCKERMAN 4
FELINE SARCOMA VIRAL
ONCOGENE HOMOLOG)
6cpy GRMZM2G135359
PSEUDOKINASE

(Zea
mays)
4 / 7 VAL A 305
VAL A 213
CYH A 225
ARG A 218
None
1.27A 1t46A-6cpyA:
21.5
1t46A-6cpyA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9U_A_CPFA5002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)
6cpy GRMZM2G135359
PSEUDOKINASE

(Zea
mays)
4 / 6 PHE A 377
ASN A 268
ARG A 355
ASN A 356
None
1.39A 1t9uA-6cpyA:
undetectable
1t9uA-6cpyA:
6.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_0
(VP39)
6cpy GRMZM2G135359
PSEUDOKINASE

(Zea
mays)
5 / 12 ILE A 338
GLY A 337
PRO A 492
ALA A 369
LEU A 314
None
0.79A 1vptA-6cpyA:
undetectable
1vptA-6cpyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APV_A_TP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)
6cpy GRMZM2G135359
PSEUDOKINASE

(Zea
mays)
5 / 12 PHE A 357
LEU A 354
HIS A 284
ALA A 370
TYR A 405
None
1.41A 3apvA-6cpyA:
undetectable
3apvA-6cpyA:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APV_B_TP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)
6cpy GRMZM2G135359
PSEUDOKINASE

(Zea
mays)
5 / 12 PHE A 357
LEU A 354
HIS A 284
ALA A 370
TYR A 405
None
1.43A 3apvB-6cpyA:
undetectable
3apvB-6cpyA:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BUF_A_AEGA394_0
(BETA-SECRETASE 1)
6cpy GRMZM2G135359
PSEUDOKINASE

(Zea
mays)
4 / 5 ASP A 445
ILE A 334
ILE A 448
GLY A 415
None
0.97A 3bufA-6cpyA:
undetectable
3bufA-6cpyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OEZ_A_STIA601_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)
6cpy GRMZM2G135359
PSEUDOKINASE

(Zea
mays)
4 / 5 VAL A 480
ILE A 338
MET A 329
ARG A 464
None
1.21A 3oezA-6cpyA:
20.2
3oezA-6cpyA:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PYY_B_STIB4_2
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)
6cpy GRMZM2G135359
PSEUDOKINASE

(Zea
mays)
4 / 5 VAL A 480
ILE A 338
MET A 329
ARG A 464
None
1.37A 3pyyB-6cpyA:
20.8
3pyyB-6cpyA:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HWK_C_SFYC804_0
(SEPIAPTERIN
REDUCTASE)
6cpy GRMZM2G135359
PSEUDOKINASE

(Zea
mays)
5 / 12 LEU A 240
LEU A 364
PRO A 310
ALA A 252
MET A 288
None
1.44A 4hwkC-6cpyA:
undetectable
4hwkC-6cpyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G08_A_Z80A1187_1
(FREQUENIN 2)
6cpy GRMZM2G135359
PSEUDOKINASE

(Zea
mays)
4 / 6 ILE A 251
PHE A 306
PHE A 228
THR A 301
None
1.12A 5g08A-6cpyA:
undetectable
5g08A-6cpyA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_0
(TUBULIN BETA-2B
CHAIN)
6cpy GRMZM2G135359
PSEUDOKINASE

(Zea
mays)
5 / 11 VAL A 362
SER A 359
ASP A 358
GLU A 411
LEU A 364
None
1.41A 5jh7B-6cpyA:
undetectable
5jh7B-6cpyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_D_6K9D502_0
(TUBULIN BETA-2B
CHAIN)
6cpy GRMZM2G135359
PSEUDOKINASE

(Zea
mays)
5 / 11 VAL A 362
SER A 359
ASP A 358
GLU A 411
LEU A 364
None
1.42A 5jh7D-6cpyA:
undetectable
5jh7D-6cpyA:
undetectable