SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6cqo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GEB_A_CAMA418_0
(CYTOCHROME P450-CAM)		 6cqo SINGLE-STRANDED
DNA-BINDING PROTEIN
RIM1, MITOCHONDRIAL
(Saccharomyces
cerevisiae) 		5 / 9 LEU A  44
VAL A  65
ILE A 113
VAL A  84
ILE A  48
 None
 1.36A 1gebA-6cqoA:
undetectable		 1gebA-6cqoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_SAMA401_1
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 6cqo SINGLE-STRANDED
DNA-BINDING PROTEIN
RIM1, MITOCHONDRIAL
(Saccharomyces
cerevisiae) 		3 / 3 GLU A  87
ASP A 112
ASP A  89
 None
 0.77A 4gc9A-6cqoA:
undetectable		 4gc9A-6cqoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DNV_A_BEZA304_0
(SHKAI2IB)		 6cqo SINGLE-STRANDED
DNA-BINDING PROTEIN
RIM1, MITOCHONDRIAL
(Saccharomyces
cerevisiae) 		4 / 5 GLN A 110
ILE A  63
ILE A  24
TYR A  46
 None
 1.23A 5dnvA-6cqoA:
undetectable		 5dnvA-6cqoA:
undetectable