SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6cr0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_CCSA381_0
(ESTROGEN RECEPTOR)		 6cr0 (S)-6-HYDROXYNICOTIN
E OXIDASE
(Shinella
sp.
HZN7) 		4 / 5 HIS A 412
ALA A 418
SER A 421
HIS A  67
 None
FAD  A 507 (-3.4A)
None
None
 1.40A 1errA-6cr0A:
undetectable
1errB-6cr0A:
undetectable		 1errA-6cr0A:
undetectable
1errB-6cr0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K5Q_B_PACB559_0
(PENICILLIN G ACYLASE
ALPHA SUBUNIT
PENICILLIN G ACYLASE
BETA SUBUNIT)		 6cr0 (S)-6-HYDROXYNICOTIN
E OXIDASE
(Shinella
sp.
HZN7) 		4 / 7 SER A  25
ALA A  20
SER A  30
ALA A 223
 None
 0.83A 1k5qA-6cr0A:
undetectable
1k5qB-6cr0A:
undetectable		 1k5qA-6cr0A:
19.56
1k5qB-6cr0A:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_A_BEZA349_0
(D-AMINO ACID OXIDASE)		 6cr0 (S)-6-HYDROXYNICOTIN
E OXIDASE
(Shinella
sp.
HZN7) 		4 / 5 TYR A 367
ILE A  56
ARG A  37
GLY A  42
 None
None
FAD  A 507 (-4.4A)
FAD  A 507 (-3.1A)
 1.22A 1kifA-6cr0A:
12.4		 1kifA-6cr0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_B_BEZB349_0
(D-AMINO ACID OXIDASE)		 6cr0 (S)-6-HYDROXYNICOTIN
E OXIDASE
(Shinella
sp.
HZN7) 		4 / 5 TYR A 367
ILE A  56
ARG A  37
GLY A  42
 None
None
FAD  A 507 (-4.4A)
FAD  A 507 (-3.1A)
 1.22A 1kifB-6cr0A:
12.4		 1kifB-6cr0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_C_BEZC349_0
(D-AMINO ACID OXIDASE)		 6cr0 (S)-6-HYDROXYNICOTIN
E OXIDASE
(Shinella
sp.
HZN7) 		4 / 5 TYR A 367
ILE A  56
ARG A  37
GLY A  42
 None
None
FAD  A 507 (-4.4A)
FAD  A 507 (-3.1A)
 1.22A 1kifC-6cr0A:
12.5		 1kifC-6cr0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_D_BEZD349_0
(D-AMINO ACID OXIDASE)		 6cr0 (S)-6-HYDROXYNICOTIN
E OXIDASE
(Shinella
sp.
HZN7) 		4 / 5 TYR A 367
ILE A  56
ARG A  37
GLY A  42
 None
None
FAD  A 507 (-4.4A)
FAD  A 507 (-3.1A)
 1.22A 1kifD-6cr0A:
12.2		 1kifD-6cr0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_E_BEZE349_0
(D-AMINO ACID OXIDASE)		 6cr0 (S)-6-HYDROXYNICOTIN
E OXIDASE
(Shinella
sp.
HZN7) 		4 / 5 TYR A 367
ILE A  56
ARG A  37
GLY A  42
 None
None
FAD  A 507 (-4.4A)
FAD  A 507 (-3.1A)
 1.22A 1kifE-6cr0A:
12.4		 1kifE-6cr0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_F_BEZF349_0
(D-AMINO ACID OXIDASE)		 6cr0 (S)-6-HYDROXYNICOTIN
E OXIDASE
(Shinella
sp.
HZN7) 		4 / 5 TYR A 367
ILE A  56
ARG A  37
GLY A  42
 None
None
FAD  A 507 (-4.4A)
FAD  A 507 (-3.1A)
 1.22A 1kifF-6cr0A:
12.4		 1kifF-6cr0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_G_BEZG349_0
(D-AMINO ACID OXIDASE)		 6cr0 (S)-6-HYDROXYNICOTIN
E OXIDASE
(Shinella
sp.
HZN7) 		4 / 5 TYR A 367
ILE A  56
ARG A  37
GLY A  42
 None
None
FAD  A 507 (-4.4A)
FAD  A 507 (-3.1A)
 1.22A 1kifG-6cr0A:
12.4		 1kifG-6cr0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_H_BEZH349_0
(D-AMINO ACID OXIDASE)		 6cr0 (S)-6-HYDROXYNICOTIN
E OXIDASE
(Shinella
sp.
HZN7) 		4 / 5 TYR A 367
ILE A  56
ARG A  37
GLY A  42
 None
None
FAD  A 507 (-4.4A)
FAD  A 507 (-3.1A)
 1.22A 1kifH-6cr0A:
12.5		 1kifH-6cr0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_A_ADNA1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6cr0 (S)-6-HYDROXYNICOTIN
E OXIDASE
(Shinella
sp.
HZN7) 		5 / 11 THR A 407
GLY A 417
GLU A 286
SER A 421
ILE A 415
 None
None
None
None
FAD  A 507 (-3.7A)
 1.04A 1odiA-6cr0A:
undetectable		 1odiA-6cr0A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_B_ADNB1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6cr0 (S)-6-HYDROXYNICOTIN
E OXIDASE
(Shinella
sp.
HZN7) 		5 / 11 THR A 407
GLY A 417
GLU A 286
SER A 421
ILE A 415
 None
None
None
None
FAD  A 507 (-3.7A)
 1.02A 1odiB-6cr0A:
undetectable		 1odiB-6cr0A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_C_ADNC1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6cr0 (S)-6-HYDROXYNICOTIN
E OXIDASE
(Shinella
sp.
HZN7) 		5 / 11 THR A 407
GLY A 417
GLU A 286
SER A 421
ILE A 415
 None
None
None
None
FAD  A 507 (-3.7A)
 0.99A 1odiC-6cr0A:
undetectable		 1odiC-6cr0A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_D_ADND1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6cr0 (S)-6-HYDROXYNICOTIN
E OXIDASE
(Shinella
sp.
HZN7) 		5 / 11 THR A 407
GLY A 417
GLU A 286
SER A 421
ILE A 415
 None
None
None
None
FAD  A 507 (-3.7A)
 0.99A 1odiD-6cr0A:
undetectable		 1odiD-6cr0A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_E_ADNE1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6cr0 (S)-6-HYDROXYNICOTIN
E OXIDASE
(Shinella
sp.
HZN7) 		5 / 11 THR A 407
GLY A 417
GLU A 286
SER A 421
ILE A 415
 None
None
None
None
FAD  A 507 (-3.7A)
 1.06A 1odiE-6cr0A:
undetectable		 1odiE-6cr0A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_F_ADNF1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6cr0 (S)-6-HYDROXYNICOTIN
E OXIDASE
(Shinella
sp.
HZN7) 		5 / 11 THR A 407
GLY A 417
GLU A 286
SER A 421
ILE A 415
 None
None
None
None
FAD  A 507 (-3.7A)
 1.02A 1odiF-6cr0A:
undetectable		 1odiF-6cr0A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE9_A_BEZA352_0
(D-AMINO ACID OXIDASE)		 6cr0 (S)-6-HYDROXYNICOTIN
E OXIDASE
(Shinella
sp.
HZN7) 		4 / 5 TYR A 367
ILE A  56
ARG A  37
GLY A  42
 None
None
FAD  A 507 (-4.4A)
FAD  A 507 (-3.1A)
 1.29A 1ve9A-6cr0A:
12.5		 1ve9A-6cr0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_E_SAME301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 6cr0 (S)-6-HYDROXYNICOTIN
E OXIDASE
(Shinella
sp.
HZN7) 		5 / 12 GLY A 290
ARG A  43
ASP A 289
ALA A 288
ALA A 381
 None
FAD  A 507 (-4.0A)
None
None
None
 1.07A 2br4E-6cr0A:
undetectable		 2br4E-6cr0A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_G_BEZG2352_0
(D-AMINO-ACID OXIDASE)		 6cr0 (S)-6-HYDROXYNICOTIN
E OXIDASE
(Shinella
sp.
HZN7) 		4 / 5 TYR A 367
ILE A  56
ARG A  37
GLY A  42
 None
None
FAD  A 507 (-4.4A)
FAD  A 507 (-3.1A)
 1.29A 2du8G-6cr0A:
12.5		 2du8G-6cr0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_J_BEZJ3352_0
(D-AMINO-ACID OXIDASE)		 6cr0 (S)-6-HYDROXYNICOTIN
E OXIDASE
(Shinella
sp.
HZN7) 		4 / 5 TYR A 367
ILE A  56
ARG A  37
GLY A  42
 None
None
FAD  A 507 (-4.4A)
FAD  A 507 (-3.1A)
 1.32A 2du8J-6cr0A:
12.4		 2du8J-6cr0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA601_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 6cr0 (S)-6-HYDROXYNICOTIN
E OXIDASE
(Shinella
sp.
HZN7) 		4 / 7 GLY A  14
ALA A 418
VAL A 257
ILE A  33
 FAD  A 507 ( 3.7A)
FAD  A 507 (-3.4A)
None
None
 0.79A 3a2qA-6cr0A:
undetectable		 3a2qA-6cr0A:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APW_A_DP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 6cr0 (S)-6-HYDROXYNICOTIN
E OXIDASE
(Shinella
sp.
HZN7) 		5 / 12 VAL A  10
ILE A  33
GLU A  35
ALA A 418
SER A 421
 None
None
FAD  A 507 (-2.7A)
FAD  A 507 (-3.4A)
None
 1.32A 3apwA-6cr0A:
undetectable		 3apwA-6cr0A:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_B_PM6B302_1
(THIOPURINE
S-METHYLTRANSFERASE)		 6cr0 (S)-6-HYDROXYNICOTIN
E OXIDASE
(Shinella
sp.
HZN7) 		4 / 7 PHE A 118
LEU A 150
LEU A 155
LEU A 153
 None
 0.90A 3bgdB-6cr0A:
undetectable		 3bgdB-6cr0A:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 6cr0 (S)-6-HYDROXYNICOTIN
E OXIDASE
(Shinella
sp.
HZN7) 		4 / 6 THR A 198
PHE A 115
PHE A 183
TYR A 170
 None
None
None
MPD  A 505 (-3.8A)
 1.27A 3elzB-6cr0A:
undetectable		 3elzB-6cr0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU9_B_SPMB700_1
(POLYAMINE OXIDASE)		 6cr0 (S)-6-HYDROXYNICOTIN
E OXIDASE
(Shinella
sp.
HZN7) 		4 / 7 GLU A 166
TYR A 414
GLU A 201
TYR A 111
 MPD  A 504 (-3.5A)
MPD  A 505 ( 3.8A)
MPD  A 504 (-3.2A)
MPD  A 503 (-3.8A)
 1.10A 3ku9B-6cr0A:
35.1		 3ku9B-6cr0A:
10.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UAW_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 6cr0 (S)-6-HYDROXYNICOTIN
E OXIDASE
(Shinella
sp.
HZN7) 		5 / 11 THR A 407
GLY A 417
GLU A 286
SER A 421
ILE A 415
 None
None
None
None
FAD  A 507 (-3.7A)
 1.14A 3uawA-6cr0A:
undetectable		 3uawA-6cr0A:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F84_A_SAMA501_0
(GERANYL DIPHOSPHATE
2-C-METHYLTRANSFERAS
E)		 6cr0 (S)-6-HYDROXYNICOTIN
E OXIDASE
(Shinella
sp.
HZN7) 		5 / 12 GLY A  12
GLY A  17
THR A 259
LEU A 258
VAL A 231
 FAD  A 507 (-3.4A)
None
None
None
FAD  A 507 (-3.8A)
 1.20A 4f84A-6cr0A:
undetectable		 4f84A-6cr0A:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0B_B_SAMB504_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 6cr0 (S)-6-HYDROXYNICOTIN
E OXIDASE
(Shinella
sp.
HZN7) 		4 / 8 HIS A  67
PRO A  66
ASP A 416
ALA A 408
 None
 1.02A 4k0bB-6cr0A:
undetectable		 4k0bB-6cr0A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KUK_A_RBFA201_1
(BLUE-LIGHT
PHOTORECEPTOR)		 6cr0 (S)-6-HYDROXYNICOTIN
E OXIDASE
(Shinella
sp.
HZN7) 		5 / 12 ASN A 315
ASN A 368
LEU A 342
ILE A 340
GLN A 337
 None
 1.42A 4kukA-6cr0A:
undetectable		 4kukA-6cr0A:
24.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L7I_B_SAMB501_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 6cr0 (S)-6-HYDROXYNICOTIN
E OXIDASE
(Shinella
sp.
HZN7) 		4 / 8 HIS A  67
PRO A  66
ASP A 416
ALA A 408
 None
 1.06A 4l7iB-6cr0A:
undetectable		 4l7iB-6cr0A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_D_SAMD301_0
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 6cr0 (S)-6-HYDROXYNICOTIN
E OXIDASE
(Shinella
sp.
HZN7) 		5 / 12 GLY A 422
GLY A 404
ILE A 419
ALA A  20
ARG A  74
 None
FAD  A 507 (-3.2A)
None
None
None
 1.17A 4qtuD-6cr0A:
2.1		 4qtuD-6cr0A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDT_A_ACTA409_0
(FAD:PROTEIN FMN
TRANSFERASE)		 6cr0 (S)-6-HYDROXYNICOTIN
E OXIDASE
(Shinella
sp.
HZN7) 		4 / 5 VAL A 425
ILE A 429
VAL A 257
THR A 255
 None
 0.74A 4xdtA-6cr0A:
undetectable		 4xdtA-6cr0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6cr0 (S)-6-HYDROXYNICOTIN
E OXIDASE
(Shinella
sp.
HZN7) 		4 / 8 SER A 421
GLY A  12
ALA A  20
THR A 259
 None
FAD  A 507 (-3.4A)
None
None
 0.93A 5eevL-6cr0A:
undetectable
5eevV-6cr0A:
undetectable		 5eevL-6cr0A:
10.14
5eevV-6cr0A:
10.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6cr0 (S)-6-HYDROXYNICOTIN
E OXIDASE
(Shinella
sp.
HZN7) 		4 / 8 SER A 421
GLY A  12
ALA A  20
THR A 259
 None
FAD  A 507 (-3.4A)
None
None
 0.92A 5eewL-6cr0A:
undetectable
5eewV-6cr0A:
undetectable		 5eewL-6cr0A:
10.14
5eewV-6cr0A:
10.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6cr0 (S)-6-HYDROXYNICOTIN
E OXIDASE
(Shinella
sp.
HZN7) 		4 / 8 SER A 421
GLY A  12
ALA A  20
THR A 259
 None
FAD  A 507 (-3.4A)
None
None
 0.93A 5ef3L-6cr0A:
undetectable
5ef3V-6cr0A:
undetectable		 5ef3L-6cr0A:
10.14
5ef3V-6cr0A:
10.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_B_SAMB303_1
(METHYLTRANSFERASE)		 6cr0 (S)-6-HYDROXYNICOTIN
E OXIDASE
(Shinella
sp.
HZN7) 		4 / 7 GLY A 172
SER A 378
ARG A 147
ASP A 289
 None
 1.10A 5n5dB-6cr0A:
undetectable		 5n5dB-6cr0A:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND2_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 6cr0 (S)-6-HYDROXYNICOTIN
E OXIDASE
(Shinella
sp.
HZN7) 		5 / 12 GLU A  71
ALA A 216
ARG A  39
ARG A  22
LEU A  18
 None
 1.23A 5nd2B-6cr0A:
undetectable		 5nd2B-6cr0A:
9.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_2_PQN2843_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6cr0 (S)-6-HYDROXYNICOTIN
E OXIDASE
(Shinella
sp.
HZN7) 		5 / 12 ILE A 415
SER A 225
ALA A  21
LEU A  18
ALA A  13
 FAD  A 507 (-3.7A)
None
None
None
None
 1.17A 5oy02-6cr0A:
undetectable		 5oy02-6cr0A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_B_SAMB601_1
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 6cr0 (S)-6-HYDROXYNICOTIN
E OXIDASE
(Shinella
sp.
HZN7) 		4 / 7 ALA A 403
GLY A  17
GLY A  12
THR A 407
 None
None
FAD  A 507 (-3.4A)
None
 0.73A 5ybbB-6cr0A:
undetectable		 5ybbB-6cr0A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZSF_A_6T0A910_0
(TOLL-LIKE RECEPTOR 7)		 6cr0 (S)-6-HYDROXYNICOTIN
E OXIDASE
(Shinella
sp.
HZN7) 		4 / 7 THR A 168
LEU A 169
ILE A 334
THR A 333
 None
MPD  A 505 ( 4.5A)
None
MPD  A 505 ( 4.5A)
 1.03A 5zsfA-6cr0A:
undetectable
5zsfB-6cr0A:
undetectable		 5zsfA-6cr0A:
16.67
5zsfB-6cr0A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		 6cr0 (S)-6-HYDROXYNICOTIN
E OXIDASE
(Shinella
sp.
HZN7) 		5 / 9 ALA A 418
SER A  16
GLY A 422
ALA A 406
SER A 405
 FAD  A 507 (-3.4A)
FAD  A 507 (-2.7A)
None
None
FAD  A 507 (-2.9A)
 1.12A 6bklE-6cr0A:
undetectable
6bklF-6cr0A:
undetectable
6bklG-6cr0A:
undetectable
6bklH-6cr0A:
undetectable		 6bklE-6cr0A:
undetectable
6bklF-6cr0A:
undetectable
6bklG-6cr0A:
undetectable
6bklH-6cr0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CR0_A_ACTA506_0
((S)-6-HYDROXYNICOTIN
E OXIDASE)		 6cr0 (S)-6-HYDROXYNICOTIN
E OXIDASE
(Shinella
sp.
HZN7) 		4 / 4 ALA A  82
HIS A 205
TYR A 320
LYS A 331
 ACT  A 506 ( 3.8A)
ACT  A 506 (-4.0A)
ACT  A 506 (-4.7A)
None
 0.00A 6cr0A-6cr0A:
73.3		 6cr0A-6cr0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FDY_U_DB8U302_1
(-)		 6cr0 (S)-6-HYDROXYNICOTIN
E OXIDASE
(Shinella
sp.
HZN7) 		5 / 9 LEU A 260
PRO A 230
VAL A  11
LEU A 245
ILE A  34
 FAD  A 507 (-4.3A)
FAD  A 507 (-4.6A)
FAD  A 507 (-4.8A)
None
None
 1.26A 6fdyU-6cr0A:
undetectable		 6fdyU-6cr0A:
17.06