SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6cud'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_A_SHHA2452_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 6cud SHORT TRANSIENT
RECEPTOR POTENTIAL
CHANNEL 3
(Homo
sapiens) 		5 / 11 LEU A 275
PHE A 308
HIS A 311
ASP A 263
GLY A 260
 None
 1.05A 1zz1A-6cudA:
undetectable		 1zz1A-6cudA:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_A_H4BA1290_1
(PTERIDINE REDUCTASE
1)		 6cud SHORT TRANSIENT
RECEPTOR POTENTIAL
CHANNEL 3
(Homo
sapiens) 		4 / 8 PHE A  31
LEU A  47
LEU A  87
LEU A  66
 None
 0.93A 2bfpA-6cudA:
undetectable		 2bfpA-6cudA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_D_H4BD1290_1
(PTERIDINE REDUCTASE
1)		 6cud SHORT TRANSIENT
RECEPTOR POTENTIAL
CHANNEL 3
(Homo
sapiens) 		4 / 8 PHE A  31
LEU A  47
LEU A  87
LEU A  66
 None
 0.94A 2bfpD-6cudA:
undetectable		 2bfpD-6cudA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_A_BEZA1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 6cud SHORT TRANSIENT
RECEPTOR POTENTIAL
CHANNEL 3
(Homo
sapiens) 		5 / 10 LEU A 385
GLY A 386
LEU A 387
LEU A 388
ILE A 429
 None
 0.97A 2f8dA-6cudA:
undetectable		 2f8dA-6cudA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_B_BEZB1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 6cud SHORT TRANSIENT
RECEPTOR POTENTIAL
CHANNEL 3
(Homo
sapiens) 		5 / 10 LEU A 385
GLY A 386
LEU A 387
LEU A 388
ILE A 429
 None
 1.00A 2f8dB-6cudA:
undetectable		 2f8dB-6cudA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RCT_A_RTLA140_1
(RETINOL-BINDING
PROTEIN II, CELLULAR)		 6cud SHORT TRANSIENT
RECEPTOR POTENTIAL
CHANNEL 3
(Homo
sapiens) 		3 / 3 GLN A 481
THR A 419
TRP A 517
 None
 1.08A 2rctA-6cudA:
undetectable		 2rctA-6cudA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUR_B_PFLB407_1
(PROTON-GATED ION
CHANNEL)		 6cud SHORT TRANSIENT
RECEPTOR POTENTIAL
CHANNEL 3
(Homo
sapiens) 		4 / 7 TYR A 774
ILE A 771
MET A 767
ILE A 274
 None
 0.91A 5murB-6cudA:
4.5		 5murB-6cudA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X66_D_MTXD402_1
(THYMIDYLATE SYNTHASE)		 6cud SHORT TRANSIENT
RECEPTOR POTENTIAL
CHANNEL 3
(Homo
sapiens) 		5 / 10 ARG A 296
ILE A 771
ASP A 263
GLY A 260
PHE A 257
 None
 1.29A 5x66D-6cudA:
undetectable		 5x66D-6cudA:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BP4_A_SAMA505_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC)		 6cud SHORT TRANSIENT
RECEPTOR POTENTIAL
CHANNEL 3
(Homo
sapiens) 		3 / 3 ILE A 766
ASN A 276
CYH A 314
 None
 0.74A 6bp4A-6cudA:
undetectable		 6bp4A-6cudA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_A_CXQA507_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 6cud SHORT TRANSIENT
RECEPTOR POTENTIAL
CHANNEL 3
(Homo
sapiens) 		4 / 5 ARG A 475
ALA A 471
TYR A 530
ILE A 429
 None
 1.36A 6f6sA-6cudA:
undetectable
6f6sB-6cudA:
undetectable		 6f6sA-6cudA:
23.16
6f6sB-6cudA:
21.43