SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6cuf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_A_IBPA2001_1
(SERUM ALBUMIN)		 6cuf -
(-) 		5 / 11 ARG 7  39
VAL 7  58
GLY 7  57
ALA 7  55
LEU 7  47
 None
 1.06A 2bxgA-6cuf7:
undetectable		 2bxgA-6cuf7:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_B_NCAB1246_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 6cuf -
(-) 		4 / 7 GLY 8  65
SER 8  68
SER 8  82
GLU 8  81
 None
 0.93A 2c8aB-6cuf8:
undetectable		 2c8aB-6cuf8:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_D_NCAD1247_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 6cuf -
(-) 		4 / 7 GLY 8  65
SER 8  68
SER 8  82
GLU 8  81
 None
 0.97A 2c8aD-6cuf8:
undetectable		 2c8aD-6cuf8:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 6cuf -
(-) 		3 / 3 ARG 6  31
ILE 6  48
TRP 6  35
 None
 1.05A 2nodB-6cuf6:
undetectable		 2nodB-6cuf6:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 6cuf -
(-) 		4 / 7 MET 8  69
ILE 8  48
ARG 8  38
GLY 8  65
 None
 1.20A 2pnjB-6cuf8:
undetectable		 2pnjB-6cuf8:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMZ_A_LDPA501_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE)		 6cuf -
(-) 		4 / 7 GLY 7  30
GLN 7  90
PHE 7  91
ILE 7   2
 None
 0.98A 2qmzA-6cuf7:
undetectable
2qmzB-6cuf7:
undetectable		 2qmzA-6cuf7:
undetectable
2qmzB-6cuf7:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA304_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 6cuf -
(-) 		4 / 4 GLN 6  17
PRO 6  15
VAL 6  78
GLU 6  79
 None
 1.06A 3huoA-6cuf6:
undetectable		 3huoA-6cuf6:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_B_BCZB468_1
(NEURAMINIDASE)		 6cuf -
(-) 		3 / 3 ARG 5  66
GLU 5  46
TYR 5  90
 None
 0.92A 3k37B-6cuf5:
undetectable		 3k37B-6cuf5:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 6cuf -
(-) 		3 / 3 ARG 6  31
ILE 6  48
TRP 6  35
 None
 1.06A 3nw2A-6cuf6:
undetectable		 3nw2A-6cuf6:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 6cuf -
(-) 		3 / 3 ARG 6  31
ILE 6  48
TRP 6  35
 None
 1.05A 3nw2B-6cuf6:
undetectable		 3nw2B-6cuf6:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_D_SUED1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 6cuf -
(-) 		3 / 3 TYR 5  33
LEU 5  63
LYS 5  64
 None
 0.77A 3sueD-6cuf5:
undetectable		 3sueD-6cuf5:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 6cuf

(;
) 		4 / 8 ILE 8  20
PRO 7  44
VAL 8  93
TRP 8 103
 None
 1.11A 4f4dB-6cuf8:
undetectable		 4f4dB-6cuf8:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_B_FOLB301_1
(FOLATE RECEPTOR
ALPHA)		 6cuf

(;
) 		3 / 3 ASP 5  56
TRP 6  91
SER 5  35
 None
 0.97A 4lrhB-6cuf5:
undetectable		 4lrhB-6cuf5:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_B_FOLB301_1
(FOLATE RECEPTOR
ALPHA)		 6cuf

(;
) 		3 / 3 ASP 5  56
TRP 6  96
SER 5  35
 None
 0.97A 4lrhB-6cuf5:
undetectable		 4lrhB-6cuf5:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_F_FOLF301_1
(FOLATE RECEPTOR
ALPHA)		 6cuf

(;
) 		3 / 3 ASP 5  56
TRP 6  91
SER 5  35
 None
 0.88A 4lrhF-6cuf5:
undetectable		 4lrhF-6cuf5:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_F_FOLF301_1
(FOLATE RECEPTOR
ALPHA)		 6cuf

(;
) 		3 / 3 ASP 5  56
TRP 6  96
SER 5  35
 None
 0.94A 4lrhF-6cuf5:
undetectable		 4lrhF-6cuf5:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M7K_H_ACTH302_0
(10H10 HEAVY CHAIN)		 6cuf -
(-) 		4 / 5 VAL 8   2
TYR 8  27
ARG 8  94
TYR 8 102
 None
 0.42A 4m7kH-6cuf8:
20.1		 4m7kH-6cuf8:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_2
(ADENOSINE KINASE)		 6cuf -
(-) 		4 / 4 LEU 7 104
SER 7 102
LEU 7  73
LEU 7  13
 None
 1.11A 4n09A-6cuf7:
undetectable		 4n09A-6cuf7:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOG_B_ML1B302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 6cuf -
(-) 		4 / 6 GLY 7  30
GLN 7  90
PHE 7  91
ILE 7   2
 None
 0.88A 4qogA-6cuf7:
undetectable
4qogB-6cuf7:
undetectable		 4qogA-6cuf7:
undetectable
4qogB-6cuf7:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUC_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 6cuf

(;
) 		5 / 12 ASN 5  23
VAL 5  24
ILE 5  37
ILE 5  89
GLN 6  38
 None
 1.42A 4xucA-6cuf5:
undetectable		 4xucA-6cuf5:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ALB_L_TIQL1210_2
(MEDI2452 LIGHT CHAIN)		 6cuf
() 		4 / 8 GLY 6  29
TYR 5 100
GLY 6  67
PHE 6  67
 None
 0.88A 5albL-6cuf6:
14.7		 5albL-6cuf6:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_C_9UQC202_0
(CEREBLON ISOFORM 4)		 6cuf

(;
) 		4 / 8 GLU 7  96
PHE 7  91
TRP 8  47
TRP 8  50
 None
 1.41A 5oh1C-6cuf7:
undetectable		 5oh1C-6cuf7:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGG_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6cuf -
(-) 		4 / 4 VAL 8 109
VAL 8 108
TYR 8  90
GLN 8   6
 None
 1.48A 5qggA-6cuf8:
undetectable		 5qggA-6cuf8:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGO_A_ACTA302_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6cuf -
(-) 		4 / 4 VAL 8 109
VAL 8 108
TYR 8  90
GLN 8   6
 None
 1.49A 5qgoA-6cuf8:
undetectable		 5qgoA-6cuf8:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGP_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6cuf -
(-) 		4 / 4 VAL 8 109
VAL 8 108
TYR 8  90
GLN 8   6
 None
 1.50A 5qgpA-6cuf8:
undetectable		 5qgpA-6cuf8:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGQ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6cuf -
(-) 		4 / 4 VAL 8 109
VAL 8 108
TYR 8  90
GLN 8   6
 None
 1.48A 5qgqA-6cuf8:
undetectable		 5qgqA-6cuf8:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHB_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6cuf -
(-) 		4 / 4 VAL 8 109
VAL 8 108
TYR 8  90
GLN 8   6
 None
 1.49A 5qhbA-6cuf8:
undetectable		 5qhbA-6cuf8:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Z_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 6cuf -
(-) 		5 / 12 ILE 8  48
ALA 8  60
GLN 8  64
LEU 8  63
ILE 8  20
 None
 1.13A 6a5zD-6cuf8:
undetectable		 6a5zD-6cuf8:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_1
(BETA-1 ADRENERGIC
RECEPTOR)		 6cuf

(;
) 		4 / 6 GLY 8  44
LEU 7 100
PHE 7  97
PHE 8 100
 None
 1.05A 6h7lA-6cuf8:
undetectable		 6h7lA-6cuf8:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_1
(BETA-1 ADRENERGIC
RECEPTOR)		 6cuf

(;
) 		4 / 6 GLY 8  44
LEU 7 100
PHE 7  97
PHE 8 100
 None
 1.05A 6h7lB-6cuf8:
undetectable		 6h7lB-6cuf8:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IBL_A_H98A501_0
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 6cuf -
(-) 		5 / 12 THR 5  83
VAL 5 109
VAL 5 107
VAL 5  67
TYR 5  90
 None
 1.46A 6iblA-6cuf5:
undetectable		 6iblA-6cuf5:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IBL_A_H98A501_0
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 6cuf -
(-) 		5 / 12 THR 8  83
VAL 8 111
VAL 8 109
VAL 8  67
TYR 8  90
 None
 1.25A 6iblA-6cuf8:
undetectable		 6iblA-6cuf8:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IBL_B_H98B501_0
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 6cuf -
(-) 		5 / 12 THR 8  83
VAL 8 111
VAL 8 109
VAL 8  67
TYR 8  90
 None
 1.26A 6iblB-6cuf8:
undetectable		 6iblB-6cuf8:
undetectable