SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6cuq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QYX_A_ASDA500_1
(ESTRADIOL 17
BETA-DEHYDROGENASE 1)		 6cuq MACROPHAGE MIGRATION
INHIBITORY
FACTOR-LIKE PROTEIN
(Entamoeba
histolytica) 		5 / 9 LEU A  75
PRO A   2
TYR A  79
SER A  24
GLU A  30
 None
 1.39A 1qyxA-6cuqA:
undetectable		 1qyxA-6cuqA:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EBZ_B_017B201_1
(PROTEASE)		 6cuq MACROPHAGE MIGRATION
INHIBITORY
FACTOR-LIKE PROTEIN
(Entamoeba
histolytica) 		5 / 11 LEU A  83
ALA A  10
GLY A  48
ILE A  94
ILE A  89
 None
 0.74A 3ebzA-6cuqA:
undetectable		 3ebzA-6cuqA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EBZ_B_017B201_1
(PROTEASE)		 6cuq MACROPHAGE MIGRATION
INHIBITORY
FACTOR-LIKE PROTEIN
(Entamoeba
histolytica) 		5 / 11 LEU A  83
ALA A  10
GLY A  49
ILE A  94
ILE A  89
 None
 0.99A 3ebzA-6cuqA:
undetectable		 3ebzA-6cuqA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S45_B_478B201_2
(PROTEASE)		 6cuq MACROPHAGE MIGRATION
INHIBITORY
FACTOR-LIKE PROTEIN
(Entamoeba
histolytica) 		5 / 11 LEU A  83
ALA A  10
GLY A  48
ILE A  94
ILE A  89
 None
 0.76A 3s45B-6cuqA:
undetectable		 3s45B-6cuqA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S53_A_017A201_2
(PROTEASE)		 6cuq MACROPHAGE MIGRATION
INHIBITORY
FACTOR-LIKE PROTEIN
(Entamoeba
histolytica) 		5 / 11 LEU A  83
ALA A  10
GLY A  48
ILE A  94
ILE A  89
 None
 0.72A 3s53B-6cuqA:
undetectable		 3s53B-6cuqA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KMM_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 6cuq MACROPHAGE MIGRATION
INHIBITORY
FACTOR-LIKE PROTEIN
(Entamoeba
histolytica) 		4 / 5 LEU A  96
ARG A  78
PRO A   2
SER A  64
 None
 1.27A 4kmmB-6cuqA:
undetectable		 4kmmB-6cuqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_D_AQ4D602_0
(CYTOCHROME P450 1A1)		 6cuq MACROPHAGE MIGRATION
INHIBITORY
FACTOR-LIKE PROTEIN
(Entamoeba
histolytica) 		5 / 12 ILE A  94
GLY A  88
ALA A  87
ILE A   6
LEU A  82
 None
 1.10A 6dwnD-6cuqA:
undetectable		 6dwnD-6cuqA:
19.32