SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6cv7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1BDW_B_DVAB8_0 (GRAMICIDIN A)	6cv7	- (-)	3 / 3	VAL A 60 VAL A 94 TRP A 63	EDO A 407 (-4.2A) None None	0.95A	1bdwA-6cv7A: undetectable 1bdwB-6cv7A: undetectable	1bdwA-6cv7A: undetectable 1bdwB-6cv7A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FSL_B_NIOB145_1 (LEGHEMOGLOBIN A)	6cv7	- (-)	4 / 8	ILE A 364 PHE A 340 LEU A 328 VAL A 332	None	0.86A	1fslB-6cv7A: undetectable	1fslB-6cv7A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1S9Q_A_CHDA459_0 (ESTROGEN-RELATED RECEPTOR GAMMA)	6cv7	- (-)	4 / 6	ASP A 341 LEU A 342 VAL A 343 ILE A 344	None	0.93A	1s9qA-6cv7A: undetectable	1s9qA-6cv7A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G2O_A_SAMA500_1 (PCZA361.24)	6cv7	- (-)	3 / 3	ARG A 298 GLU A 137 ASP A 203	None CA A 404 (-2.9A) None	0.94A	3g2oA-6cv7A: undetectable	3g2oA-6cv7A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NAI_A_URFA521_1 (RNA DEPENDENT RNA POLYMERASE)	6cv7	- (-)	4 / 5	ASP A 85 ASP A 159 ASP A 118 ARG A 119	CA A 402 ( 2.1A) CA A 402 ( 3.3A) CA A 402 (-3.0A) None	1.30A	3naiA-6cv7A: undetectable	3naiA-6cv7A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NAI_A_URFA521_1 (RNA DEPENDENT RNA POLYMERASE)	6cv7	- (-)	4 / 5	ASP A 118 ASP A 85 ASP A 159 ARG A 224	CA A 402 (-3.0A) CA A 402 ( 2.1A) CA A 402 ( 3.3A) None	1.39A	3naiA-6cv7A: undetectable	3naiA-6cv7A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YNI_A_SAMA401_0 (NSP16 PROTEIN)	6cv7	- (-)	5 / 12	GLY A 237 GLY A 241 ASP A 236 ASN A 291 ASP A 238	CA A 404 (-4.2A) CA A 405 ( 4.5A) CA A 404 (-3.2A) None CA A 405 (-3.3A)	1.26A	5yniA-6cv7A: undetectable	5yniA-6cv7A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YNM_A_SAMA401_0 (NSP16 PROTEIN)	6cv7	- (-)	5 / 12	GLY A 237 GLY A 241 ASP A 236 ASN A 291 ASP A 238	CA A 404 (-4.2A) CA A 405 ( 4.5A) CA A 404 (-3.2A) None CA A 405 (-3.3A)	1.27A	5ynmA-6cv7A: undetectable	5ynmA-6cv7A: undetectable

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1BDW_B_DVAB8_0","GRAMICIDIN A","6cv7","-","-",3,"VAL A  60;VAL A  94;TRP A  63","EDO A 407 (-4.2A);None;None","0.95A","1bdwA-6cv7A:undetectable;1bdwB-6cv7A:undetectable","1bdwA-6cv7A:undetectable;1bdwB-6cv7A:undetectable"],["1FSL_B_NIOB145_1","LEGHEMOGLOBIN A","6cv7","-","-",4,"ILE A 364;PHE A 340;LEU A 328;VAL A 332","None","0.86A","1fslB-6cv7A:undetectable","1fslB-6cv7A:undetectable"],["1S9Q_A_CHDA459_0","ESTROGEN-RELATED RECEPTOR GAMMA","6cv7","-","-",4,"ASP A 341;LEU A 342;VAL A 343;ILE A 344","None","0.93A","1s9qA-6cv7A:undetectable","1s9qA-6cv7A:undetectable"],["3G2O_A_SAMA500_1","PCZA361.24","6cv7","-","-",3,"ARG A 298;GLU A 137;ASP A 203","None; CA A 404 (-2.9A);None","0.94A","3g2oA-6cv7A:undetectable","3g2oA-6cv7A:undetectable"],["3NAI_A_URFA521_1","RNA DEPENDENT RNA POLYMERASE","6cv7","-","-",4,"ASP A  85;ASP A 159;ASP A 118;ARG A 119"," CA A 402 ( 2.1A); CA A 402 ( 3.3A); CA A 402 (-3.0A);None","1.30A","3naiA-6cv7A:undetectable","3naiA-6cv7A:undetectable"],["3NAI_A_URFA521_1","RNA DEPENDENT RNA POLYMERASE","6cv7","-","-",4,"ASP A 118;ASP A  85;ASP A 159;ARG A 224"," CA A 402 (-3.0A); CA A 402 ( 2.1A); CA A 402 ( 3.3A);None","1.39A","3naiA-6cv7A:undetectable","3naiA-6cv7A:undetectable"],["5YNI_A_SAMA401_0","NSP16 PROTEIN","6cv7","-","-",5,"GLY A 237;GLY A 241;ASP A 236;ASN A 291;ASP A 238"," CA A 404 (-4.2A); CA A 405 ( 4.5A); CA A 404 (-3.2A);None; CA A 405 (-3.3A)","1.26A","5yniA-6cv7A:undetectable","5yniA-6cv7A:undetectable"],["5YNM_A_SAMA401_0","NSP16 PROTEIN","6cv7","-","-",5,"GLY A 237;GLY A 241;ASP A 236;ASN A 291;ASP A 238"," CA A 404 (-4.2A); CA A 405 ( 4.5A); CA A 404 (-3.2A);None; CA A 405 (-3.3A)","1.27A","5ynmA-6cv7A:undetectable","5ynmA-6cv7A:undetectable"]]