SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6cv9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_A_ESTA600_1
(ESTRADIOL RECEPTOR)		 6cv9 SHORT TRANSIENT
RECEPTOR POTENTIAL
CHANNEL 6
(Mus
musculus) 		5 / 10 ALA A 105
GLU A 106
LEU A 138
ILE A 175
LEU A 151
 None
 1.35A 1qkuA-6cv9A:
undetectable		 1qkuA-6cv9A:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_B_ESTB600_1
(ESTRADIOL RECEPTOR)		 6cv9 SHORT TRANSIENT
RECEPTOR POTENTIAL
CHANNEL 6
(Mus
musculus) 		5 / 10 ALA A 105
GLU A 106
LEU A 138
ILE A 175
LEU A 151
 None
 1.35A 1qkuB-6cv9A:
undetectable		 1qkuB-6cv9A:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_C_ESTC600_1
(ESTRADIOL RECEPTOR)		 6cv9 SHORT TRANSIENT
RECEPTOR POTENTIAL
CHANNEL 6
(Mus
musculus) 		5 / 10 ALA A 105
GLU A 106
LEU A 138
ILE A 175
LEU A 151
 None
 1.34A 1qkuC-6cv9A:
undetectable		 1qkuC-6cv9A:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1100_1
(SERUM ALBUMIN)		 6cv9 SHORT TRANSIENT
RECEPTOR POTENTIAL
CHANNEL 6
(Mus
musculus) 		4 / 6 HIS A 182
PHE A 185
ARG A 159
GLY A 161
 None
 1.48A 2i30A-6cv9A:
undetectable		 2i30A-6cv9A:
8.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_E_ASDE1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 6cv9 SHORT TRANSIENT
RECEPTOR POTENTIAL
CHANNEL 6
(Mus
musculus) 		5 / 9 LEU A 145
LEU A 152
ALA A 139
LEU A 136
ALA A 163
 None
 1.19A 2vcvE-6cv9A:
3.8		 2vcvE-6cv9A:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6cv9 SHORT TRANSIENT
RECEPTOR POTENTIAL
CHANNEL 6
(Mus
musculus) 		5 / 9 GLN A 201
ALA A 184
PHE A 185
LEU A 136
VAL A 140
 None
 1.15A 3claA-6cv9A:
undetectable		 3claA-6cv9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PP1_A_ACTA590_0
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 6cv9 SHORT TRANSIENT
RECEPTOR POTENTIAL
CHANNEL 6
(Mus
musculus) 		4 / 5 GLU A 106
GLN A 888
HIS A 144
GLY A 108
 None
 0.98A 3pp1A-6cv9A:
undetectable		 3pp1A-6cv9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB504_1
(HEMOLYTIC LECTIN
CEL-III)		 6cv9 SHORT TRANSIENT
RECEPTOR POTENTIAL
CHANNEL 6
(Mus
musculus) 		4 / 5 ASP A 203
GLU A 210
GLY A 212
TYR A 206
 None
 1.08A 3w9tB-6cv9A:
undetectable		 3w9tB-6cv9A:
10.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1005_1
(HEMOLYTIC LECTIN
CEL-III)		 6cv9 SHORT TRANSIENT
RECEPTOR POTENTIAL
CHANNEL 6
(Mus
musculus) 		3 / 3 ASP A 203
GLY A 212
TYR A 206
 None
 0.72A 3w9tC-6cv9A:
undetectable		 3w9tC-6cv9A:
10.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD506_1
(HEMOLYTIC LECTIN
CEL-III)		 6cv9 SHORT TRANSIENT
RECEPTOR POTENTIAL
CHANNEL 6
(Mus
musculus) 		4 / 5 ASP A 203
GLU A 210
GLY A 212
TYR A 206
 None
 1.06A 3w9tD-6cv9A:
undetectable		 3w9tD-6cv9A:
10.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE505_1
(HEMOLYTIC LECTIN
CEL-III)		 6cv9 SHORT TRANSIENT
RECEPTOR POTENTIAL
CHANNEL 6
(Mus
musculus) 		4 / 5 ASP A 203
GLU A 210
GLY A 212
TYR A 206
 None
 1.01A 3w9tE-6cv9A:
undetectable		 3w9tE-6cv9A:
10.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG503_1
(HEMOLYTIC LECTIN
CEL-III)		 6cv9 SHORT TRANSIENT
RECEPTOR POTENTIAL
CHANNEL 6
(Mus
musculus) 		3 / 3 ASP A 203
GLY A 212
TYR A 206
 None
 0.70A 3w9tG-6cv9A:
undetectable		 3w9tG-6cv9A:
10.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG505_1
(HEMOLYTIC LECTIN
CEL-III)		 6cv9 SHORT TRANSIENT
RECEPTOR POTENTIAL
CHANNEL 6
(Mus
musculus) 		4 / 5 ASP A 203
GLU A 210
GLY A 212
TYR A 206
 None
 1.02A 3w9tG-6cv9A:
undetectable		 3w9tG-6cv9A:
10.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 6cv9 SHORT TRANSIENT
RECEPTOR POTENTIAL
CHANNEL 6
(Mus
musculus) 		4 / 6 ASN A 904
GLU A 900
GLU A 899
GLU A 906
 None
 1.38A 4mi4A-6cv9A:
undetectable		 4mi4A-6cv9A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 6cv9 SHORT TRANSIENT
RECEPTOR POTENTIAL
CHANNEL 6
(Mus
musculus) 		4 / 7 ASN A 904
GLU A 900
GLU A 899
GLU A 906
 None
 1.31A 4mj8C-6cv9A:
undetectable		 4mj8C-6cv9A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMC_A_29JA603_1
(TRANSPORTER)		 6cv9 SHORT TRANSIENT
RECEPTOR POTENTIAL
CHANNEL 6
(Mus
musculus) 		5 / 10 TYR A 284
VAL A 234
GLY A 278
SER A 281
ASP A 218
 None
 1.33A 4mmcA-6cv9A:
undetectable		 4mmcA-6cv9A:
9.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KLA_A_ACTA1505_0
(MATERNAL PROTEIN
PUMILIO)		 6cv9 SHORT TRANSIENT
RECEPTOR POTENTIAL
CHANNEL 6
(Mus
musculus) 		3 / 3 HIS A 263
LYS A 262
PHE A 266
 None
 1.31A 5klaA-6cv9A:
2.0		 5klaA-6cv9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_1
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 6cv9 SHORT TRANSIENT
RECEPTOR POTENTIAL
CHANNEL 6
(Mus
musculus) 		4 / 6 ASP A 103
ASN A 109
ASN A 142
GLN A 888
 None
 1.02A 5l6eA-6cv9A:
undetectable		 5l6eA-6cv9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WEA_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 6cv9 SHORT TRANSIENT
RECEPTOR POTENTIAL
CHANNEL 6
(Mus
musculus) 		4 / 5 LEU A  94
TYR A 130
LEU A 102
GLU A 106
 None
 1.23A 5weaA-6cv9A:
undetectable		 5weaA-6cv9A:
undetectable