SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6cw5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_1
(PROTEIN (ADENOSINE
KINASE))		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
None
 0.31A 1bx4A-6cw5A:
31.2		 1bx4A-6cw5A:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LII_A_ADNA699_1
(ADENOSINE KINASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
None
 0.31A 1liiA-6cw5A:
32.1		 1liiA-6cw5A:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIK_A_ADNA699_1
(ADENOSINE KINASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
None
 0.45A 1likA-6cw5A:
31.2		 1likA-6cw5A:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT6_B_DESB128_1
(TRANSTHYRETIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		4 / 5 LEU A 194
ALA A 197
LEU A 195
SER A 200
 None
 1.11A 1tt6B-6cw5A:
undetectable		 1tt6B-6cw5A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_A_ADNA1301_1
(SUGAR KINASE MJ0406)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		6 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ALA A  96
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.6A)
None
 0.25A 2c49A-6cw5A:
33.7		 2c49A-6cw5A:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_B_ADNB1301_1
(SUGAR KINASE MJ0406)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		4 / 7 ASP A  16
GLY A  41
GLY A  42
ASN A  46
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
 0.40A 2c49B-6cw5A:
32.3		 2c49B-6cw5A:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKK_A_2FAA501_1
(ADENOSINE KINASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		7 / 12 SER A  12
ASP A  16
GLY A  41
GLY A  42
ASN A  46
GLY A 270
ASP A 273
 None
GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
None
None
 0.50A 2pkkA-6cw5A:
32.2		 2pkkA-6cw5A:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKM_A_ADNA501_1
(ADENOSINE KINASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		7 / 12 SER A  12
ASP A  16
GLY A  41
GLY A  42
ASN A  46
GLY A 270
ASP A 273
 None
GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
None
None
 0.51A 2pkmA-6cw5A:
31.8		 2pkmA-6cw5A:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_G_BEZG1222_0
(PEROXIREDOXIN 6.)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		4 / 8 PRO A 314
VAL A 313
SER A 312
ALA A 271
 None
 0.84A 2v41G-6cw5A:
undetectable
2v41H-6cw5A:
undetectable		 2v41G-6cw5A:
undetectable
2v41H-6cw5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		3 / 3 ASN A 137
ASN A 163
GLU A 190
 None
 0.90A 3kpdC-6cw5A:
undetectable		 3kpdC-6cw5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_B_SAMB401_0
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 ALA A 276
MET A 310
GLY A 270
ALA A  40
LEU A  75
 None
 1.24A 3tm4B-6cw5A:
4.0		 3tm4B-6cw5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_A_ADNA353_1
(ADENOSINE KINASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		6 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
GLY A 270
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
None
None
 0.35A 3uboA-6cw5A:
29.8		 3uboA-6cw5A:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_A_ADNA353_1
(ADENOSINE KINASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		6 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 138
GLY A 270
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 (-2.8A)
None
None
 0.90A 3uboA-6cw5A:
29.8		 3uboA-6cw5A:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_1
(ADENOSINE KINASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		6 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
THR A 269
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 ( 4.9A)
None
 0.33A 3uboB-6cw5A:
30.6		 3uboB-6cw5A:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_1
(ADENOSINE KINASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 138
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 (-2.8A)
None
 0.89A 3uboB-6cw5A:
30.6		 3uboB-6cw5A:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_A_ADNA401_1
(ADENOSINE KINASE,
PUTATIVE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		6 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
GLY A 270
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
None
None
 0.48A 3uq6A-6cw5A:
31.0		 3uq6A-6cw5A:
12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_B_ADNB401_1
(ADENOSINE KINASE,
PUTATIVE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 ASP A  16
GLY A  42
ASN A  46
GLY A 270
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
None
None
 0.46A 3uq6B-6cw5A:
29.7		 3uq6B-6cw5A:
12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		6 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
GLY A 270
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
None
None
 0.55A 3vaqA-6cw5A:
30.7		 3vaqA-6cw5A:
12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 ASP A  16
GLY A  42
ASN A  46
GLY A 270
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
None
None
 0.49A 3vaqB-6cw5A:
29.1		 3vaqB-6cw5A:
12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		6 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
GLY A 270
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
None
None
 0.50A 3vasA-6cw5A:
30.7		 3vasA-6cw5A:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		6 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
GLY A 270
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
None
None
 0.48A 3vasB-6cw5A:
21.8		 3vasB-6cw5A:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_1
(ADENOSINE KINASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 ASP A  16
GLY A  41
ASN A  46
GLY A 270
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
None
None
 0.70A 4dc3A-6cw5A:
28.6		 4dc3A-6cw5A:
12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_B_2FAB401_1
(ADENOSINE KINASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		6 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
GLY A 270
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
None
None
 0.53A 4dc3B-6cw5A:
30.8		 4dc3B-6cw5A:
12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_A_ADNA500_1
(SUGAR KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		6 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
THR A 269
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 ( 4.9A)
None
 0.32A 4e3aA-6cw5A:
30.5		 4e3aA-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_A_ADNA500_1
(SUGAR KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 138
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 (-2.8A)
None
 0.87A 4e3aA-6cw5A:
30.5		 4e3aA-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_B_ADNB500_1
(SUGAR KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		7 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
THR A 269
GLY A 270
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 ( 4.9A)
None
None
 0.33A 4e3aB-6cw5A:
30.4		 4e3aB-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_B_ADNB500_1
(SUGAR KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		6 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 138
GLY A 270
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 (-2.8A)
None
None
 0.85A 4e3aB-6cw5A:
30.4		 4e3aB-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		7 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ILE A  98
THR A 269
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
None
GOL  A 400 ( 4.9A)
None
 0.43A 4jksA-6cw5A:
30.4		 4jksA-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 138
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 (-2.8A)
None
 0.88A 4jksA-6cw5A:
30.4		 4jksA-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
ILE A 108
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 ( 4.8A)
None
 0.86A 4jksA-6cw5A:
30.4		 4jksA-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		7 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ILE A  98
THR A 269
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
None
GOL  A 400 ( 4.9A)
None
 0.43A 4jksB-6cw5A:
30.5		 4jksB-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 138
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 (-2.8A)
None
 0.88A 4jksB-6cw5A:
30.5		 4jksB-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
ILE A 108
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 ( 4.8A)
None
 0.86A 4jksB-6cw5A:
30.5		 4jksB-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_A_ADNA500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		7 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ILE A  98
THR A 269
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
None
GOL  A 400 ( 4.9A)
None
 0.42A 4jkuA-6cw5A:
30.4		 4jkuA-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_A_ADNA500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 138
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 (-2.8A)
None
 0.88A 4jkuA-6cw5A:
30.4		 4jkuA-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_A_ADNA500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
ILE A 108
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 ( 4.8A)
None
 0.84A 4jkuA-6cw5A:
30.4		 4jkuA-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_B_ADNB500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		6 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
THR A 269
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 ( 4.9A)
None
 0.31A 4jkuB-6cw5A:
30.4		 4jkuB-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_B_ADNB500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 138
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 (-2.8A)
None
 0.89A 4jkuB-6cw5A:
30.4		 4jkuB-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_1
(SUGAR KINASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		7 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ILE A  98
THR A 269
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
None
GOL  A 400 ( 4.9A)
None
 0.42A 4k8cA-6cw5A:
27.6		 4k8cA-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_1
(SUGAR KINASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 138
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 (-2.8A)
None
 0.87A 4k8cA-6cw5A:
27.6		 4k8cA-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_1
(SUGAR KINASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
ILE A 108
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 ( 4.8A)
None
 0.87A 4k8cA-6cw5A:
27.6		 4k8cA-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_B_ADNB401_1
(SUGAR KINASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		7 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ILE A  98
THR A 269
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
None
GOL  A 400 ( 4.9A)
None
 0.41A 4k8cB-6cw5A:
30.2		 4k8cB-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_B_ADNB401_1
(SUGAR KINASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 138
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 (-2.8A)
None
 0.87A 4k8cB-6cw5A:
30.2		 4k8cB-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_B_ADNB401_1
(SUGAR KINASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
ILE A 108
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 ( 4.8A)
None
 0.85A 4k8cB-6cw5A:
30.2		 4k8cB-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_A_ADNA401_1
(SUGAR KINASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		7 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ILE A  98
THR A 269
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
None
GOL  A 400 ( 4.9A)
None
 0.44A 4k8kA-6cw5A:
30.4		 4k8kA-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_A_ADNA401_1
(SUGAR KINASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 138
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 (-2.8A)
None
 0.88A 4k8kA-6cw5A:
30.4		 4k8kA-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_A_ADNA401_1
(SUGAR KINASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
ILE A 108
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 ( 4.8A)
None
 0.86A 4k8kA-6cw5A:
30.4		 4k8kA-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_B_ADNB403_1
(SUGAR KINASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		7 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ILE A  98
THR A 269
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
None
GOL  A 400 ( 4.9A)
None
 0.43A 4k8kB-6cw5A:
30.4		 4k8kB-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_B_ADNB403_1
(SUGAR KINASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 138
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 (-2.8A)
None
 0.89A 4k8kB-6cw5A:
30.4		 4k8kB-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_B_ADNB403_1
(SUGAR KINASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
ILE A 108
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 ( 4.8A)
None
 0.85A 4k8kB-6cw5A:
30.4		 4k8kB-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_A_ADNA401_1
(SUGAR KINASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		6 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
THR A 269
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 ( 4.9A)
None
 0.31A 4k8pA-6cw5A:
30.5		 4k8pA-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_A_ADNA401_1
(SUGAR KINASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 138
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 (-2.8A)
None
 0.86A 4k8pA-6cw5A:
30.5		 4k8pA-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_B_ADNB401_1
(SUGAR KINASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		6 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
THR A 269
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 ( 4.9A)
None
 0.31A 4k8pB-6cw5A:
30.4		 4k8pB-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_B_ADNB401_1
(SUGAR KINASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 138
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 (-2.8A)
None
 0.86A 4k8pB-6cw5A:
30.4		 4k8pB-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_A_ADNA401_1
(SUGAR KINASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		6 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
THR A 269
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 ( 4.9A)
None
 0.33A 4k8tA-6cw5A:
30.3		 4k8tA-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_A_ADNA401_1
(SUGAR KINASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 138
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 (-2.8A)
None
 0.86A 4k8tA-6cw5A:
30.3		 4k8tA-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_B_ADNB401_1
(SUGAR KINASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		6 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
THR A 269
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 ( 4.9A)
None
 0.35A 4k8tB-6cw5A:
30.4		 4k8tB-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_B_ADNB401_1
(SUGAR KINASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 138
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 (-2.8A)
None
 0.88A 4k8tB-6cw5A:
30.4		 4k8tB-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_A_ADNA401_1
(SUGAR KINASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		6 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
THR A 269
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 ( 4.9A)
None
 0.32A 4k93A-6cw5A:
30.4		 4k93A-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_A_ADNA401_1
(SUGAR KINASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 138
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 (-2.8A)
None
 0.87A 4k93A-6cw5A:
30.4		 4k93A-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_B_ADNB402_1
(SUGAR KINASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		6 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
THR A 269
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 ( 4.9A)
None
 0.31A 4k93B-6cw5A:
30.5		 4k93B-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_B_ADNB402_1
(SUGAR KINASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 138
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 (-2.8A)
None
 0.87A 4k93B-6cw5A:
30.5		 4k93B-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_A_ADNA401_1
(SUGAR KINASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		6 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
THR A 269
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 ( 4.9A)
None
 0.32A 4k9cA-6cw5A:
30.5		 4k9cA-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_A_ADNA401_1
(SUGAR KINASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 138
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 (-2.8A)
None
 0.87A 4k9cA-6cw5A:
30.5		 4k9cA-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_B_ADNB401_1
(SUGAR KINASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		6 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
THR A 269
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 ( 4.9A)
None
 0.30A 4k9cB-6cw5A:
30.5		 4k9cB-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_B_ADNB401_1
(SUGAR KINASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 138
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 (-2.8A)
None
 0.86A 4k9cB-6cw5A:
30.5		 4k9cB-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_A_ADNA401_1
(SUGAR KINASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		6 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
THR A 269
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 ( 4.9A)
None
 0.33A 4k9iA-6cw5A:
30.4		 4k9iA-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_A_ADNA401_1
(SUGAR KINASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 138
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 (-2.8A)
None
 0.87A 4k9iA-6cw5A:
30.4		 4k9iA-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_B_ADNB401_1
(SUGAR KINASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		6 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
THR A 269
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 ( 4.9A)
None
 0.32A 4k9iB-6cw5A:
30.5		 4k9iB-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_B_ADNB401_1
(SUGAR KINASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 138
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 (-2.8A)
None
 0.86A 4k9iB-6cw5A:
30.5		 4k9iB-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		6 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
THR A 269
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 ( 4.9A)
None
 0.31A 4kadA-6cw5A:
30.4		 4kadA-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 138
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 (-2.8A)
None
 0.87A 4kadA-6cw5A:
30.4		 4kadA-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		6 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
THR A 269
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 ( 4.9A)
None
 0.33A 4kadB-6cw5A:
27.5		 4kadB-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 138
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 (-2.8A)
None
 0.87A 4kadB-6cw5A:
27.5		 4kadB-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		7 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ILE A  98
THR A 269
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
None
GOL  A 400 ( 4.9A)
None
 0.42A 4kahA-6cw5A:
27.6		 4kahA-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 138
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 (-2.8A)
None
 0.87A 4kahA-6cw5A:
27.6		 4kahA-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
ILE A 108
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 ( 4.8A)
None
 0.87A 4kahA-6cw5A:
27.6		 4kahA-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		7 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ILE A  98
THR A 269
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
None
GOL  A 400 ( 4.9A)
None
 0.41A 4kahB-6cw5A:
30.5		 4kahB-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 138
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 (-2.8A)
None
 0.85A 4kahB-6cw5A:
30.5		 4kahB-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
ILE A 108
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 ( 4.8A)
None
 0.87A 4kahB-6cw5A:
30.5		 4kahB-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		7 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ILE A  98
THR A 269
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
None
GOL  A 400 ( 4.9A)
None
 0.42A 4kalA-6cw5A:
30.4		 4kalA-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 138
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 (-2.8A)
None
 0.87A 4kalA-6cw5A:
30.4		 4kalA-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
ILE A 108
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 ( 4.8A)
None
 0.86A 4kalA-6cw5A:
30.4		 4kalA-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		7 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ILE A  98
THR A 269
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
None
GOL  A 400 ( 4.9A)
None
 0.44A 4kalB-6cw5A:
30.4		 4kalB-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 138
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 (-2.8A)
None
 0.87A 4kalB-6cw5A:
30.4		 4kalB-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
ILE A 108
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 ( 4.8A)
None
 0.87A 4kalB-6cw5A:
30.4		 4kalB-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		7 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ILE A  98
THR A 269
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
None
GOL  A 400 ( 4.9A)
None
 0.42A 4kanA-6cw5A:
27.7		 4kanA-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 138
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 (-2.8A)
None
 0.88A 4kanA-6cw5A:
27.7		 4kanA-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
ILE A 108
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 ( 4.8A)
None
 0.86A 4kanA-6cw5A:
27.7		 4kanA-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		7 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ILE A  98
THR A 269
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
None
GOL  A 400 ( 4.9A)
None
 0.42A 4kanB-6cw5A:
30.5		 4kanB-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 138
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 (-2.8A)
None
 0.88A 4kanB-6cw5A:
30.5		 4kanB-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
ILE A 108
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 ( 4.8A)
None
 0.87A 4kanB-6cw5A:
30.5		 4kanB-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		7 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ILE A  98
THR A 269
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
None
GOL  A 400 ( 4.9A)
None
 0.44A 4kbeA-6cw5A:
30.4		 4kbeA-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 138
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 (-2.8A)
None
 0.87A 4kbeA-6cw5A:
30.4		 4kbeA-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
ILE A 108
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 ( 4.8A)
None
 0.86A 4kbeA-6cw5A:
30.4		 4kbeA-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		7 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ILE A  98
THR A 269
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
None
GOL  A 400 ( 4.9A)
None
 0.41A 4kbeB-6cw5A:
30.5		 4kbeB-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 138
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 (-2.8A)
None
 0.87A 4kbeB-6cw5A:
30.5		 4kbeB-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
ILE A 108
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 ( 4.8A)
None
 0.88A 4kbeB-6cw5A:
30.5		 4kbeB-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOT_A_CE3A205_1
(UNCHARACTERIZED
PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 PHE A 162
PRO A 164
GLY A 189
ASN A 187
LEU A 173
 None
 1.00A 4kotA-6cw5A:
undetectable		 4kotA-6cw5A:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOU_A_C04A206_1
(UNCHARACTERIZED
PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 10 PHE A 162
PRO A 164
GLY A 189
ASN A 187
LEU A 173
 None
 0.96A 4kouA-6cw5A:
undetectable		 4kouA-6cw5A:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		7 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ILE A  98
THR A 269
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
None
GOL  A 400 ( 4.9A)
None
 0.42A 4lbgA-6cw5A:
30.4		 4lbgA-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 138
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 (-2.8A)
None
 0.88A 4lbgA-6cw5A:
30.4		 4lbgA-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
ILE A 108
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 ( 4.8A)
None
 0.85A 4lbgA-6cw5A:
30.4		 4lbgA-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		7 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ILE A  98
THR A 269
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
None
GOL  A 400 ( 4.9A)
None
 0.42A 4lbgB-6cw5A:
30.5		 4lbgB-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 138
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 (-2.8A)
None
 0.88A 4lbgB-6cw5A:
30.5		 4lbgB-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
ILE A 108
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 ( 4.8A)
None
 0.86A 4lbgB-6cw5A:
30.5		 4lbgB-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		6 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
THR A 269
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 ( 4.9A)
None
 0.34A 4lbxA-6cw5A:
30.4		 4lbxA-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 138
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 (-2.8A)
None
 0.88A 4lbxA-6cw5A:
30.4		 4lbxA-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		6 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
THR A 269
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 ( 4.9A)
None
 0.33A 4lbxB-6cw5A:
30.5		 4lbxB-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 138
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 (-2.8A)
None
 0.86A 4lbxB-6cw5A:
30.5		 4lbxB-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		6 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
THR A 269
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 ( 4.9A)
None
 0.32A 4lc4A-6cw5A:
30.4		 4lc4A-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 138
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 (-2.8A)
None
 0.88A 4lc4A-6cw5A:
30.4		 4lc4A-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		6 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
THR A 269
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 ( 4.9A)
None
 0.33A 4lc4B-6cw5A:
30.3		 4lc4B-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 138
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 (-2.8A)
None
 0.88A 4lc4B-6cw5A:
30.3		 4lc4B-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		7 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ILE A  98
THR A 269
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
None
GOL  A 400 ( 4.9A)
None
 0.43A 4lcaA-6cw5A:
30.5		 4lcaA-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 138
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 (-2.8A)
None
 0.87A 4lcaA-6cw5A:
30.5		 4lcaA-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
ILE A 108
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 ( 4.8A)
None
 0.88A 4lcaA-6cw5A:
30.5		 4lcaA-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		7 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ILE A  98
THR A 269
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
None
GOL  A 400 ( 4.9A)
None
 0.43A 4lcaB-6cw5A:
30.3		 4lcaB-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 138
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 (-2.8A)
None
 0.87A 4lcaB-6cw5A:
30.3		 4lcaB-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
ILE A 108
ASP A 273
 GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
GOL  A 400 ( 4.8A)
None
 0.86A 4lcaB-6cw5A:
30.3		 4lcaB-6cw5A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_1
(ADENOSINE KINASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 ASP A  16
GLY A  42
ASN A  46
GLY A 270
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
None
None
 0.56A 4n09A-6cw5A:
31.9		 4n09A-6cw5A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_1
(ADENOSINE KINASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
None
 0.33A 4n09B-6cw5A:
31.7		 4n09B-6cw5A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_1
(ADENOSINE KINASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 ASP A  16
GLY A  42
ASN A  46
GLY A 270
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
None
None
 0.67A 4n09B-6cw5A:
31.7		 4n09B-6cw5A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_1
(ADENOSINE KINASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
None
 0.35A 4n09D-6cw5A:
31.7		 4n09D-6cw5A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_1
(ADENOSINE KINASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 12 ASP A  16
GLY A  42
ASN A  46
GLY A 270
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
None
None
 0.67A 4n09D-6cw5A:
31.7		 4n09D-6cw5A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_1
(ADENOSINE KINASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		6 / 12 SER A  12
ASP A  16
GLY A  41
GLY A  42
ASN A  46
ASP A 273
 None
GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
None
 0.48A 4ubeA-6cw5A:
32.1		 4ubeA-6cw5A:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_A_032A401_2
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		4 / 6 PHE A 279
SER A 312
VAL A 313
ASP A 273
 None
 1.25A 5hesA-6cw5A:
undetectable		 5hesA-6cw5A:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_C_AC2C301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 11 GLY A  68
ALA A  45
VAL A  71
ASP A  67
ILE A  15
 None
 1.17A 5i3cC-6cw5A:
undetectable		 5i3cC-6cw5A:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB5_A_ADNA401_1
(ADENOSINE KINASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		6 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
GLY A 270
ASP A 273
 GOL  A 400 (-2.8A)
GOL  A 400 (-3.5A)
GOL  A 400 (-3.3A)
GOL  A 400 (-3.3A)
None
None
 0.43A 5kb5A-6cw5A:
31.7		 5kb5A-6cw5A:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_A_C2FA3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		4 / 5 ASN A 163
ASP A 273
ASN A  46
ASP A  16
 None
None
GOL  A 400 (-3.3A)
GOL  A 400 (-2.8A)
 1.04A 5vooA-6cw5A:
2.6		 5vooA-6cw5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_C_C2FC702_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		4 / 5 ASN A 163
ASP A 273
ASN A  46
ASP A  16
 None
None
GOL  A 400 (-3.3A)
GOL  A 400 (-2.8A)
 1.05A 5vooC-6cw5A:
2.5		 5vooC-6cw5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_E_C2FE3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		4 / 5 ASN A 163
ASP A 273
ASN A  46
ASP A  16
 None
None
GOL  A 400 (-3.3A)
GOL  A 400 (-2.8A)
 1.09A 5vooE-6cw5A:
2.5		 5vooE-6cw5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_B_CHDB401_0
(BILE SALT HYDROLASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 10 LEU A 293
ILE A 235
LEU A 184
PHE A 162
ALA A 276
 None
 1.14A 5y7pB-6cw5A:
undetectable		 5y7pB-6cw5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_H_CHDH401_0
(BILE SALT HYDROLASE)		 6cw5 RIBOKINASE
(Cryptococcus
neoformans) 		5 / 10 LEU A 293
ILE A 235
LEU A 184
PHE A 162
ALA A 276
 None
 1.17A 5y7pH-6cw5A:
undetectable		 5y7pH-6cw5A:
undetectable