SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6cwp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 6cwp RIBONUCLEOTIDE
REDUCTASE
(Flavobacterium
johnsoniae) 		5 / 12 LEU A 107
LEU A 111
ALA A  64
SER A 185
PHE A 174
 None
 1.15A 1eqbA-6cwpA:
undetectable		 1eqbA-6cwpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 6cwp RIBONUCLEOTIDE
REDUCTASE
(Flavobacterium
johnsoniae) 		5 / 12 LEU A 107
LEU A 111
ALA A  64
SER A 185
PHE A 174
 None
 1.15A 1eqbB-6cwpA:
undetectable		 1eqbB-6cwpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 6cwp RIBONUCLEOTIDE
REDUCTASE
(Flavobacterium
johnsoniae) 		5 / 12 LEU A 107
LEU A 111
ALA A  64
SER A 185
PHE A 174
 None
 1.16A 1eqbD-6cwpA:
undetectable		 1eqbD-6cwpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_A_DAHA208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 6cwp RIBONUCLEOTIDE
REDUCTASE
(Flavobacterium
johnsoniae) 		5 / 11 GLU A  97
HIS A 100
GLU A 160
PHE A 168
GLU A 195
 MN  A 402 ( 2.4A)
MN  A 401 (-3.3A)
MN  A 402 (-2.4A)
None
MN  A 402 ( 1.9A)
 0.77A 1rnrA-6cwpA:
31.3		 1rnrA-6cwpA:
11.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_B_DAHB208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 6cwp RIBONUCLEOTIDE
REDUCTASE
(Flavobacterium
johnsoniae) 		5 / 12 GLU A  97
HIS A 100
GLU A 160
PHE A 168
GLU A 195
 MN  A 402 ( 2.4A)
MN  A 401 (-3.3A)
MN  A 402 (-2.4A)
None
MN  A 402 ( 1.9A)
 0.75A 1rnrB-6cwpA:
31.5		 1rnrB-6cwpA:
11.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_B_DAHB208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 6cwp RIBONUCLEOTIDE
REDUCTASE
(Flavobacterium
johnsoniae) 		5 / 12 GLU A  97
HIS A 100
TYR A 104
GLU A 160
GLU A 195
 MN  A 402 ( 2.4A)
MN  A 401 (-3.3A)
None
MN  A 402 (-2.4A)
MN  A 402 ( 1.9A)
 0.92A 1rnrB-6cwpA:
31.5		 1rnrB-6cwpA:
11.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 6cwp RIBONUCLEOTIDE
REDUCTASE
(Flavobacterium
johnsoniae) 		4 / 7 TRP A  74
ASP A 139
THR A 140
TYR A 148
 None
 1.40A 1v54A-6cwpA:
undetectable
1v54C-6cwpA:
3.0		 1v54A-6cwpA:
undetectable
1v54C-6cwpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 6cwp RIBONUCLEOTIDE
REDUCTASE
(Flavobacterium
johnsoniae) 		4 / 7 TRP A  74
ASP A 139
THR A 140
TYR A 148
 None
 1.39A 1v54N-6cwpA:
undetectable
1v54P-6cwpA:
3.1		 1v54N-6cwpA:
undetectable
1v54P-6cwpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 6cwp RIBONUCLEOTIDE
REDUCTASE
(Flavobacterium
johnsoniae) 		4 / 7 TRP A  74
ASP A 139
THR A 140
TYR A 148
 None
 1.38A 1v55A-6cwpA:
undetectable
1v55C-6cwpA:
3.1		 1v55A-6cwpA:
undetectable
1v55C-6cwpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YI4_A_ADNA306_1
(PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 6cwp RIBONUCLEOTIDE
REDUCTASE
(Flavobacterium
johnsoniae) 		5 / 10 PHE A 177
ILE A 170
ASP A 256
LEU A 257
ILE A 252
 None
 1.11A 1yi4A-6cwpA:
undetectable		 1yi4A-6cwpA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1435_1
(CHITINASE)		 6cwp RIBONUCLEOTIDE
REDUCTASE
(Flavobacterium
johnsoniae) 		4 / 6 TYR A 148
GLY A  88
PHE A  93
SER A  91
 None
 1.13A 2a3cA-6cwpA:
undetectable		 2a3cA-6cwpA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6cwp RIBONUCLEOTIDE
REDUCTASE
(Flavobacterium
johnsoniae) 		4 / 7 TRP A  74
ASP A 139
THR A 140
TYR A 148
 None
 1.41A 2dyrA-6cwpA:
undetectable
2dyrC-6cwpA:
3.0		 2dyrA-6cwpA:
undetectable
2dyrC-6cwpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6cwp RIBONUCLEOTIDE
REDUCTASE
(Flavobacterium
johnsoniae) 		4 / 7 TRP A  74
ASP A 139
THR A 140
TYR A 148
 None
 1.38A 2dyrN-6cwpA:
undetectable
2dyrP-6cwpA:
3.1		 2dyrN-6cwpA:
undetectable
2dyrP-6cwpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6cwp RIBONUCLEOTIDE
REDUCTASE
(Flavobacterium
johnsoniae) 		4 / 7 TRP A  74
ASP A 139
THR A 140
TYR A 148
 None
 1.38A 2eijA-6cwpA:
undetectable
2eijC-6cwpA:
3.5		 2eijA-6cwpA:
undetectable
2eijC-6cwpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6cwp RIBONUCLEOTIDE
REDUCTASE
(Flavobacterium
johnsoniae) 		4 / 7 TRP A  74
ASP A 139
THR A 140
TYR A 148
 None
 1.37A 2eijN-6cwpA:
undetectable
2eijP-6cwpA:
3.1		 2eijN-6cwpA:
undetectable
2eijP-6cwpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6cwp RIBONUCLEOTIDE
REDUCTASE
(Flavobacterium
johnsoniae) 		4 / 7 TRP A  74
ASP A 139
THR A 140
TYR A 148
 None
 1.38A 2eikA-6cwpA:
undetectable
2eikC-6cwpA:
3.1		 2eikA-6cwpA:
undetectable
2eikC-6cwpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6cwp RIBONUCLEOTIDE
REDUCTASE
(Flavobacterium
johnsoniae) 		4 / 7 TRP A  74
ASP A 139
THR A 140
TYR A 148
 None
 1.40A 2eikN-6cwpA:
undetectable
2eikP-6cwpA:
3.1		 2eikN-6cwpA:
undetectable
2eikP-6cwpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6cwp RIBONUCLEOTIDE
REDUCTASE
(Flavobacterium
johnsoniae) 		4 / 7 TRP A  74
ASP A 139
THR A 140
TYR A 148
 None
 1.39A 2eilA-6cwpA:
1.3
2eilC-6cwpA:
3.1		 2eilA-6cwpA:
undetectable
2eilC-6cwpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6cwp RIBONUCLEOTIDE
REDUCTASE
(Flavobacterium
johnsoniae) 		4 / 7 TRP A  74
ASP A 139
THR A 140
TYR A 148
 None
 1.38A 2eilN-6cwpA:
undetectable
2eilP-6cwpA:
3.1		 2eilN-6cwpA:
undetectable
2eilP-6cwpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I2Z_A_SALA1100_1
(SERUM ALBUMIN)		 6cwp RIBONUCLEOTIDE
REDUCTASE
(Flavobacterium
johnsoniae) 		4 / 5 LEU A 240
ILE A 243
ILE A 170
ALA A 169
 None
 0.69A 2i2zA-6cwpA:
undetectable		 2i2zA-6cwpA:
10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX6_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 6cwp RIBONUCLEOTIDE
REDUCTASE
(Flavobacterium
johnsoniae) 		4 / 6 PHE A  81
ILE A  77
GLY A 202
GLY A 201
 None
 0.62A 2qx6A-6cwpA:
undetectable
2qx6B-6cwpA:
undetectable		 2qx6A-6cwpA:
18.83
2qx6B-6cwpA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CHDA1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6cwp RIBONUCLEOTIDE
REDUCTASE
(Flavobacterium
johnsoniae) 		4 / 7 TRP A  74
ASP A 139
THR A 140
TYR A 148
 None
 1.39A 2y69A-6cwpA:
undetectable
2y69C-6cwpA:
3.0		 2y69A-6cwpA:
undetectable
2y69C-6cwpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0A_A_GLYA73_0
(NONSTRUCTURAL
PROTEIN 1)		 6cwp RIBONUCLEOTIDE
REDUCTASE
(Flavobacterium
johnsoniae) 		4 / 5 GLN A 167
ALA A  62
GLN A  65
ILE A  63
 None
 1.17A 2z0aA-6cwpA:
1.5		 2z0aA-6cwpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZN_B_SAMB402_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 6cwp RIBONUCLEOTIDE
REDUCTASE
(Flavobacterium
johnsoniae) 		5 / 12 TYR A 204
GLY A 202
ILE A 197
ASN A 200
ASP A 194
 None
 1.34A 2zznB-6cwpA:
undetectable		 2zznB-6cwpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6cwp RIBONUCLEOTIDE
REDUCTASE
(Flavobacterium
johnsoniae) 		4 / 7 TRP A  74
ASP A 139
THR A 140
TYR A 148
 None
 1.38A 3abkA-6cwpA:
undetectable
3abkC-6cwpA:
3.5		 3abkA-6cwpA:
undetectable
3abkC-6cwpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6cwp RIBONUCLEOTIDE
REDUCTASE
(Flavobacterium
johnsoniae) 		4 / 7 TRP A  74
ASP A 139
THR A 140
TYR A 148
 None
 1.41A 3abkN-6cwpA:
0.9
3abkP-6cwpA:
3.1		 3abkN-6cwpA:
undetectable
3abkP-6cwpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6cwp RIBONUCLEOTIDE
REDUCTASE
(Flavobacterium
johnsoniae) 		4 / 7 TRP A  74
ASP A 139
THR A 140
TYR A 148
 None
 1.42A 3abmN-6cwpA:
undetectable
3abmP-6cwpA:
3.1		 3abmN-6cwpA:
undetectable
3abmP-6cwpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6cwp RIBONUCLEOTIDE
REDUCTASE
(Flavobacterium
johnsoniae) 		4 / 7 TRP A  74
ASP A 139
THR A 140
TYR A 148
 None
 1.37A 3ag2A-6cwpA:
undetectable
3ag2C-6cwpA:
3.5		 3ag2A-6cwpA:
undetectable
3ag2C-6cwpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6cwp RIBONUCLEOTIDE
REDUCTASE
(Flavobacterium
johnsoniae) 		4 / 7 TRP A  74
ASP A 139
THR A 140
TYR A 148
 None
 1.36A 3ag2N-6cwpA:
undetectable
3ag2P-6cwpA:
3.1		 3ag2N-6cwpA:
undetectable
3ag2P-6cwpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6cwp RIBONUCLEOTIDE
REDUCTASE
(Flavobacterium
johnsoniae) 		4 / 7 TRP A  74
ASP A 139
THR A 140
TYR A 148
 None
 1.37A 3ag3A-6cwpA:
undetectable
3ag3C-6cwpA:
3.1		 3ag3A-6cwpA:
undetectable
3ag3C-6cwpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6cwp RIBONUCLEOTIDE
REDUCTASE
(Flavobacterium
johnsoniae) 		4 / 7 TRP A  74
ASP A 139
THR A 140
TYR A 148
 None
 1.39A 3ag3N-6cwpA:
undetectable
3ag3P-6cwpA:
3.1		 3ag3N-6cwpA:
undetectable
3ag3P-6cwpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6cwp RIBONUCLEOTIDE
REDUCTASE
(Flavobacterium
johnsoniae) 		4 / 7 TRP A  74
ASP A 139
THR A 140
TYR A 148
 None
 1.37A 3ag4A-6cwpA:
1.5
3ag4C-6cwpA:
3.0		 3ag4A-6cwpA:
undetectable
3ag4C-6cwpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6cwp RIBONUCLEOTIDE
REDUCTASE
(Flavobacterium
johnsoniae) 		4 / 7 TRP A  74
ASP A 139
THR A 140
TYR A 148
 None
 1.36A 3ag4N-6cwpA:
undetectable
3ag4P-6cwpA:
3.1		 3ag4N-6cwpA:
undetectable
3ag4P-6cwpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AY0_B_ADNB402_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 6cwp RIBONUCLEOTIDE
REDUCTASE
(Flavobacterium
johnsoniae) 		5 / 10 TYR A 204
GLY A 202
ILE A 197
ASN A 200
ASP A 194
 None
 1.26A 3ay0B-6cwpA:
undetectable		 3ay0B-6cwpA:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VHU_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 6cwp RIBONUCLEOTIDE
REDUCTASE
(Flavobacterium
johnsoniae) 		4 / 5 LEU A 154
LEU A 158
LEU A 133
SER A 134
 None
 0.90A 3vhuA-6cwpA:
2.8		 3vhuA-6cwpA:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1002_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 6cwp RIBONUCLEOTIDE
REDUCTASE
(Flavobacterium
johnsoniae) 		3 / 3 ASN A 186
TRP A 190
ASP A  40
 None
 1.26A 4a7tA-6cwpA:
undetectable
4a7tF-6cwpA:
undetectable		 4a7tA-6cwpA:
24.75
4a7tF-6cwpA:
24.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MS4_A_2C0A501_1
(GAMMA-AMINOBUTYRIC
ACID TYPE B RECEPTOR
SUBUNIT 1)		 6cwp RIBONUCLEOTIDE
REDUCTASE
(Flavobacterium
johnsoniae) 		4 / 8 TRP A  30
HIS A 100
TYR A  29
ILE A  25
 None
MN  A 401 (-3.3A)
None
None
 0.99A 4ms4A-6cwpA:
undetectable		 4ms4A-6cwpA:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 6cwp RIBONUCLEOTIDE
REDUCTASE
(Flavobacterium
johnsoniae) 		4 / 6 GLN A 167
PHE A 165
PHE A 291
LEU A 172
 None
 1.12A 5b1bC-6cwpA:
3.1
5b1bJ-6cwpA:
undetectable		 5b1bC-6cwpA:
undetectable
5b1bJ-6cwpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6cwp RIBONUCLEOTIDE
REDUCTASE
(Flavobacterium
johnsoniae) 		4 / 7 TRP A  74
ASP A 139
THR A 140
TYR A 148
 None
 1.38A 5b1bN-6cwpA:
undetectable
5b1bP-6cwpA:
2.9		 5b1bN-6cwpA:
undetectable
5b1bP-6cwpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6cwp RIBONUCLEOTIDE
REDUCTASE
(Flavobacterium
johnsoniae) 		4 / 7 TRP A  74
ASP A 139
THR A 140
TYR A 148
 None
 1.39A 5b3sN-6cwpA:
undetectable
5b3sP-6cwpA:
3.1		 5b3sN-6cwpA:
undetectable
5b3sP-6cwpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_2_BEZ2801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 6cwp RIBONUCLEOTIDE
REDUCTASE
(Flavobacterium
johnsoniae) 		4 / 4 LEU A  61
ARG A 129
ILE A 126
ILE A 239
 None
 1.41A 5dzk2-6cwpA:
undetectable
5dzkM-6cwpA:
undetectable
5dzkN-6cwpA:
undetectable		 5dzk2-6cwpA:
undetectable
5dzkM-6cwpA:
undetectable
5dzkN-6cwpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6cwp RIBONUCLEOTIDE
REDUCTASE
(Flavobacterium
johnsoniae) 		4 / 7 TRP A  74
ASP A 139
THR A 140
TYR A 148
 None
 1.39A 5iy5A-6cwpA:
undetectable
5iy5C-6cwpA:
3.1		 5iy5A-6cwpA:
undetectable
5iy5C-6cwpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6cwp RIBONUCLEOTIDE
REDUCTASE
(Flavobacterium
johnsoniae) 		4 / 7 TRP A  74
ASP A 139
THR A 140
TYR A 148
 None
 1.42A 5x1fN-6cwpA:
undetectable
5x1fP-6cwpA:
undetectable		 5x1fN-6cwpA:
undetectable
5x1fP-6cwpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6cwp RIBONUCLEOTIDE
REDUCTASE
(Flavobacterium
johnsoniae) 		4 / 7 TRP A  74
ASP A 139
THR A 140
TYR A 148
 None
 1.39A 5zcqN-6cwpA:
undetectable
5zcqP-6cwpA:
3.1		 5zcqN-6cwpA:
undetectable
5zcqP-6cwpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBF_A_ACTA507_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 6cwp RIBONUCLEOTIDE
REDUCTASE
(Flavobacterium
johnsoniae) 		3 / 3 LYS A 178
SER A 173
SER A 251
 None
 1.01A 6gbfA-6cwpA:
undetectable		 6gbfA-6cwpA:
undetectable