SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6cy1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_B_DVAB6_0
(GRAMICIDIN A)		 6cy1 SIGNAL RECOGNITION
PARTICLE RECEPTOR
FTSY
(Elizabethkingia
anophelis) 		3 / 3 TRP A 164
ALA A 157
VAL A 125
 None
 0.94A 1bdwA-6cy1A:
undetectable
1bdwB-6cy1A:
undetectable		 1bdwA-6cy1A:
undetectable
1bdwB-6cy1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OHR_A_1UNA201_1
(ASPARTYLPROTEASE)		 6cy1 SIGNAL RECOGNITION
PARTICLE RECEPTOR
FTSY
(Elizabethkingia
anophelis) 		6 / 11 ALA A 150
ASP A 151
ASP A 203
PRO A 233
VAL A 116
ILE A 202
 None
 1.39A 1ohrA-6cy1A:
undetectable		 1ohrA-6cy1A:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_A_9CRA502_1
(CYTOCHROME P450 2C8)		 6cy1 SIGNAL RECOGNITION
PARTICLE RECEPTOR
FTSY
(Elizabethkingia
anophelis) 		5 / 12 ILE A  70
ILE A  66
LEU A  89
VAL A  58
VAL A 310
 None
 1.02A 2nnhA-6cy1A:
undetectable		 2nnhA-6cy1A:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_B_9CRB502_1
(CYTOCHROME P450 2C8)		 6cy1 SIGNAL RECOGNITION
PARTICLE RECEPTOR
FTSY
(Elizabethkingia
anophelis) 		5 / 10 ILE A  70
ILE A  66
LEU A  89
ASN A  87
VAL A 310
 None
 1.13A 2nnhB-6cy1A:
undetectable		 2nnhB-6cy1A:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 6cy1 SIGNAL RECOGNITION
PARTICLE RECEPTOR
FTSY
(Elizabethkingia
anophelis) 		5 / 12 GLY A 306
VAL A 266
GLY A 276
VAL A 294
ILE A 292
 None
 0.91A 2pynA-6cy1A:
undetectable		 2pynA-6cy1A:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 6cy1 SIGNAL RECOGNITION
PARTICLE RECEPTOR
FTSY
(Elizabethkingia
anophelis) 		5 / 12 GLY A 306
VAL A 266
GLY A 276
VAL A 294
ILE A 292
 None
 0.91A 2pynB-6cy1A:
undetectable		 2pynB-6cy1A:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHC_B_AB1B9001_2
(PROTEASE RETROPEPSIN)		 6cy1 SIGNAL RECOGNITION
PARTICLE RECEPTOR
FTSY
(Elizabethkingia
anophelis) 		5 / 12 GLY A 306
VAL A 266
GLY A 276
VAL A 294
ILE A 292
 None
 0.82A 2qhcB-6cy1A:
undetectable		 2qhcB-6cy1A:
24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_B_1UNB900_2
(PROTEASE)		 6cy1 SIGNAL RECOGNITION
PARTICLE RECEPTOR
FTSY
(Elizabethkingia
anophelis) 		6 / 11 ALA A 150
ASP A 151
ASP A 203
PRO A 233
VAL A 116
ILE A 202
 None
 1.37A 2r5qB-6cy1A:
undetectable		 2r5qB-6cy1A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z54_A_AB1A200_1
(HIV-1 PROTEASE)		 6cy1 SIGNAL RECOGNITION
PARTICLE RECEPTOR
FTSY
(Elizabethkingia
anophelis) 		5 / 12 GLY A 306
VAL A 266
GLY A 276
VAL A 294
ILE A 292
 None
 0.92A 2z54A-6cy1A:
undetectable		 2z54A-6cy1A:
24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_A_PM6A302_1
(THIOPURINE
S-METHYLTRANSFERASE)		 6cy1 SIGNAL RECOGNITION
PARTICLE RECEPTOR
FTSY
(Elizabethkingia
anophelis) 		4 / 6 THR A 256
PHE A 255
LEU A 264
LEU A 240
 None
 1.17A 3bgdA-6cy1A:
undetectable		 3bgdA-6cy1A:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F78_A_ICFA1_1
(INTEGRIN ALPHA-L)		 6cy1 SIGNAL RECOGNITION
PARTICLE RECEPTOR
FTSY
(Elizabethkingia
anophelis) 		5 / 9 ILE A 279
ILE A  66
LYS A  65
LEU A  96
LEU A  97
 None
 1.16A 3f78A-6cy1A:
3.0		 3f78A-6cy1A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F78_B_ICFB2_1
(INTEGRIN ALPHA-L)		 6cy1 SIGNAL RECOGNITION
PARTICLE RECEPTOR
FTSY
(Elizabethkingia
anophelis) 		5 / 9 ILE A 279
ILE A  66
LYS A  65
LEU A  96
LEU A  97
 None
 1.20A 3f78B-6cy1A:
undetectable		 3f78B-6cy1A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_1
(PROTEASE)		 6cy1 SIGNAL RECOGNITION
PARTICLE RECEPTOR
FTSY
(Elizabethkingia
anophelis) 		5 / 12 GLY A 306
VAL A 266
GLY A 276
VAL A 294
ILE A 292
 None
 0.91A 3nduC-6cy1A:
undetectable		 3nduC-6cy1A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_C_BEZC264_0
(ECHA1_1)		 6cy1 SIGNAL RECOGNITION
PARTICLE RECEPTOR
FTSY
(Elizabethkingia
anophelis) 		4 / 5 ALA A 182
GLU A 217
ALA A 150
MET A 118
 None
 1.19A 3r9tC-6cy1A:
undetectable		 3r9tC-6cy1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CD2_A_FOLA207_0
(DIHYDROFOLATE
REDUCTASE)		 6cy1 SIGNAL RECOGNITION
PARTICLE RECEPTOR
FTSY
(Elizabethkingia
anophelis) 		5 / 12 ILE A 292
ILE A 279
PHE A 309
THR A 272
PHE A  27
 None
None
None
EDO  A 401 (-3.9A)
None
 1.28A 4cd2A-6cy1A:
undetectable		 4cd2A-6cy1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 6cy1 SIGNAL RECOGNITION
PARTICLE RECEPTOR
FTSY
(Elizabethkingia
anophelis) 		5 / 12 GLY A 276
ILE A 281
GLY A 242
GLY A  19
PHE A 304
 None
 1.00A 5d4uA-6cy1A:
undetectable		 5d4uA-6cy1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_B_SAMB301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 6cy1 SIGNAL RECOGNITION
PARTICLE RECEPTOR
FTSY
(Elizabethkingia
anophelis) 		5 / 12 GLY A 276
ILE A 281
GLY A 242
GLY A  19
PHE A 304
 None
 1.10A 5d4uB-6cy1A:
undetectable		 5d4uB-6cy1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K9D_A_CE9A402_0
(DIHYDROOROTATE
DEHYDROGENASE
(QUINONE),
MITOCHONDRIAL)		 6cy1 SIGNAL RECOGNITION
PARTICLE RECEPTOR
FTSY
(Elizabethkingia
anophelis) 		5 / 12 ALA A 248
ALA A 252
PHE A 255
THR A 256
PHE A 285
 None
 0.89A 5k9dA-6cy1A:
undetectable		 5k9dA-6cy1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_E_CVIE301_0
(REGULATORY PROTEIN
TETR)		 6cy1 SIGNAL RECOGNITION
PARTICLE RECEPTOR
FTSY
(Elizabethkingia
anophelis) 		5 / 12 MET A 298
LEU A 134
ILE A 131
TRP A 164
VAL A 170
 None
 1.41A 5vlmE-6cy1A:
undetectable		 5vlmE-6cy1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_0
(PROTEASE)		 6cy1 SIGNAL RECOGNITION
PARTICLE RECEPTOR
FTSY
(Elizabethkingia
anophelis) 		5 / 12 GLY A 306
VAL A 266
GLY A 276
VAL A 294
ILE A 292
 None
 0.90A 6dgxA-6cy1A:
undetectable		 6dgxA-6cy1A:
19.75