SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6cza'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_A_RBFA501_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 6cza -
(-) 		5 / 12 GLY A 348
SER A 344
ILE A 354
ILE A 271
LEU A 279
 None
None
None
MGD  A 902 ( 4.6A)
None
 1.02A 1kyvA-6czaA:
undetectable
1kyvE-6czaA:
undetectable		 1kyvA-6czaA:
undetectable
1kyvE-6czaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_C_RBFC503_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 6cza -
(-) 		5 / 12 ILE A 271
LEU A 279
GLY A 348
SER A 344
ILE A 354
 MGD  A 902 ( 4.6A)
None
None
None
None
 1.01A 1kyvB-6czaA:
undetectable
1kyvC-6czaA:
undetectable		 1kyvB-6czaA:
undetectable
1kyvC-6czaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_D_RBFD504_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 6cza -
(-) 		5 / 12 ILE A 271
LEU A 279
GLY A 348
SER A 344
ILE A 354
 MGD  A 902 ( 4.6A)
None
None
None
None
 1.02A 1kyvC-6czaA:
undetectable
1kyvD-6czaA:
undetectable		 1kyvC-6czaA:
undetectable
1kyvD-6czaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_E_RBFE505_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 6cza -
(-) 		5 / 12 ILE A 271
LEU A 279
GLY A 348
SER A 344
ILE A 354
 MGD  A 902 ( 4.6A)
None
None
None
None
 1.03A 1kyvD-6czaA:
undetectable
1kyvE-6czaA:
undetectable		 1kyvD-6czaA:
undetectable
1kyvE-6czaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRJ_A_ADNA300_1
(ALPHA-TRICHOSANTHIN)		 6cza -
(-) 		4 / 8 ILE A 458
GLY A 454
SER A 191
GLU A 195
 None
None
None
PO4  A 909 ( 4.2A)
 0.76A 1mrjA-6czaA:
undetectable		 1mrjA-6czaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q8J_A_C2FA801_0
(5-METHYLTETRAHYDROFO
LATE S-HOMOCYSTEINE
METHYLTRANSFERASE)		 6cza -
(-) 		5 / 12 ASN A 827
ASP A 722
ASP A 754
GLY A 824
ARG A 125
 MGD  A 903 (-2.2A)
MGD  A 903 ( 2.1A)
None
None
None
 1.45A 1q8jA-6czaA:
undetectable		 1q8jA-6czaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQF_A_SAMA430_1
(SUN PROTEIN)		 6cza -
(-) 		3 / 3 PRO A 273
ASP A 276
ASP A 255
 MGD  A 902 (-4.0A)
MGD  A 902 (-1.9A)
MGD  A 902 (-2.3A)
 0.81A 1sqfA-6czaA:
undetectable		 1sqfA-6czaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_A_THHA3001_1
(AMINOMETHYLTRANSFERA
SE)		 6cza -
(-) 		3 / 3 ASP A 561
GLU A 730
TYR A 809
 MGD  A 903 (-3.0A)
MGD  A 902 ( 4.1A)
MGD  A 903 (-4.1A)
 0.84A 1wsvA-6czaA:
undetectable		 1wsvA-6czaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_A_ACTA294_0
(GLYCINE
N-METHYLTRANSFERASE)		 6cza -
(-) 		4 / 5 TRP A 242
ILE A 229
LEU A 246
ALA A 265
 None
 1.26A 1xvaA-6czaA:
undetectable
1xvaB-6czaA:
undetectable		 1xvaA-6czaA:
undetectable
1xvaB-6czaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YNN_C_RFPC1120_1
(DNA-DIRECTED RNA
POLYMERASE BETA
CHAIN)		 6cza -
(-) 		5 / 12 ASP B   8
SER B 201
LEU B 193
PRO B 209
ILE B 204
 None
 1.24A 1ynnC-6czaB:
undetectable		 1ynnC-6czaB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC8_0
(ACTINOMYCIN D)		 6cza -
(-) 		3 / 3 PRO A 121
THR A 119
PRO A 129
 None
 0.83A 2d55C-6czaA:
undetectable		 2d55C-6czaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_C_SAMC1003_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 6cza -
(-) 		4 / 4 ASP A 126
ASP A 128
ASP A 495
GLY A 818
 None
 1.41A 2igtC-6czaA:
3.7		 2igtC-6czaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_A_9CRA502_1
(CYTOCHROME P450 2C8)		 6cza -
(-) 		5 / 12 ILE A 354
ILE A 357
LEU A 279
VAL A 252
VAL A 370
 None
 0.95A 2nnhA-6czaA:
undetectable		 2nnhA-6czaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O01_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 6cza -
(-) 		4 / 8 TRP A 331
SER A 388
ALA A 334
LEU A 335
 None
 0.78A 2o01A-6czaA:
undetectable		 2o01A-6czaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 6cza -
(-) 		5 / 12 LEU A 668
MET A 199
ILE A 683
SER A 388
HIS A 703
 None
 1.26A 2pnjB-6czaA:
undetectable		 2pnjB-6czaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_B_KLNB1498_1
(CYTOCHROME P450 3A4)		 6cza -
(-) 		5 / 9 ILE A 774
ALA A 756
GLU A 715
GLY A 781
LEU A 829
 None
 1.23A 2v0mB-6czaA:
undetectable		 2v0mB-6czaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_C_SAMC530_1
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 6cza -
(-) 		3 / 3 TYR A 809
GLU A 513
ASN A 827
 MGD  A 903 (-4.1A)
None
MGD  A 903 (-2.2A)
 0.97A 2y7hC-6czaA:
undetectable		 2y7hC-6czaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YY8_B_SAMB500_0
(UPF0106 PROTEIN
PH0461)		 6cza -
(-) 		5 / 11 VAL A 292
GLY A 291
ILE A 283
GLU A 290
ALA A 358
 None
 0.85A 2yy8A-6czaA:
2.5
2yy8B-6czaA:
2.4		 2yy8A-6czaA:
undetectable
2yy8B-6czaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBU_D_ADND504_1
(UNCHARACTERIZED
CONSERVED PROTEIN)		 6cza -
(-) 		3 / 3 PHE A 802
ASN A 827
PHE A 843
 MGD  A 903 (-3.7A)
MGD  A 903 (-2.2A)
MGD  A 903 (-4.2A)
 0.97A 2zbuD-6czaA:
undetectable		 2zbuD-6czaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUL_A_SAMA376_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 6cza -
(-) 		5 / 12 GLY A 805
GLY A 823
LEU A 783
ASN A 826
PHE A 486
 None
None
None
MGD  A 903 ( 4.6A)
None
 1.11A 2zulA-6czaA:
undetectable		 2zulA-6czaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A25_A_SAMA279_1
(UNCHARACTERIZED
PROTEIN PH0793)		 6cza

(;
) 		3 / 3 MET A  75
GLU B  25
ASP B 168
 FMT  A 907 ( 4.6A)
None
None
 1.06A 3a25A-6czaA:
undetectable		 3a25A-6czaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA1_0
(FERROCHELATASE)		 6cza -
(-) 		5 / 11 LEU A 668
MET A 199
ILE A 683
SER A 388
HIS A 703
 None
 1.18A 3aqiA-6czaA:
undetectable		 3aqiA-6czaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_A_DR7A100_2
(PROTEASE)		 6cza -
(-) 		5 / 9 ALA A 462
ASP A 438
LEU A 161
VAL A 501
ILE A 466
 None
 1.09A 3em4B-6czaA:
undetectable		 3em4B-6czaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_C_486C4_2
(GLUCOCORTICOID
RECEPTOR)		 6cza -
(-) 		3 / 3 MET B   5
CYH B 183
PRO B  54
 None
SF4  B 301 (-2.3A)
SF4  B 301 ( 4.8A)
 1.17A 3h52C-6czaB:
undetectable		 3h52C-6czaB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LTW_A_HLZA302_1
(ARYLAMINE
N-ACETYLTRANSFERASE
NAT)		 6cza -
(-) 		4 / 6 LEU A 719
PRO A 256
ARG A 709
HIS A 846
 None
MGD  A 902 (-4.5A)
None
None
 1.49A 3ltwA-6czaA:
undetectable		 3ltwA-6czaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA358_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 6cza -
(-) 		3 / 3 HIS A 526
HIS A 527
MET A 528
 MGD  A 903 ( 4.0A)
MGD  A 903 ( 3.8A)
None
 1.00A 3mihA-6czaA:
undetectable		 3mihA-6czaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OLS_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 6cza -
(-) 		5 / 12 LEU A 395
LEU A 392
ALA A 391
LEU A 335
GLY A 326
 None
 1.06A 3olsA-6czaA:
undetectable		 3olsA-6czaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		 6cza
() 		5 / 10 ILE A 269
TYR B 234
THR A 353
ILE A 357
ILE A 354
 None
 1.07A 3p4wD-6czaA:
undetectable		 3p4wD-6czaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_E_DSFE319_1
(GLR4197 PROTEIN)		 6cza
() 		5 / 10 ILE A 269
TYR B 234
THR A 353
ILE A 357
ILE A 354
 None
 1.08A 3p4wE-6czaA:
undetectable		 3p4wE-6czaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QF1_A_PZEA6951_1
(LACTOPEROXIDASE)		 6cza -
(-) 		3 / 3 HIS B 169
ARG B 148
GLU B 147
 None
 1.12A 3qf1A-6czaB:
undetectable		 3qf1A-6czaB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_A_ACTA5_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 6cza -
(-) 		3 / 3 LYS A 216
SER A  94
GLN A 240
 None
 1.18A 3si7A-6czaA:
undetectable		 3si7A-6czaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 6cza -
(-) 		4 / 4 ASN A 728
GLY A 803
ASP A 832
ASP A 722
 MGD  A 902 (-4.8A)
None
None
MGD  A 903 ( 2.1A)
 1.36A 4n49A-6czaA:
undetectable		 4n49A-6czaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA304_1
(TYROSINASE)		 6cza
() 		4 / 5 LEU B  83
HIS B  75
GLU A  43
THR B 151
 None
 1.45A 4p6sA-6czaB:
undetectable		 4p6sA-6czaB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_A_HFGA803_1
(PROLINE--TRNA LIGASE)		 6cza -
(-) 		3 / 3 GLU A 648
THR A 322
HIS A 323
 None
 0.82A 4q15A-6czaA:
undetectable		 4q15A-6czaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_B_HFGB803_1
(PROLINE--TRNA LIGASE)		 6cza -
(-) 		3 / 3 GLU A 648
THR A 322
HIS A 323
 None
 0.84A 4q15B-6czaA:
undetectable		 4q15B-6czaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN)		 6cza -
(-) 		5 / 12 GLY A 398
ILE A 357
ALA A 358
MET A 361
GLY A 362
 None
 0.83A 4r29D-6czaA:
undetectable		 4r29D-6czaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6cza -
(-) 		4 / 8 PHE A 301
SER A 315
VAL A 328
TRP A 331
 None
 1.23A 4v3yA-6czaA:
undetectable
4v3yB-6czaA:
undetectable		 4v3yA-6czaA:
undetectable
4v3yB-6czaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_D_LOCD502_1
(TUBULIN BETA CHAIN)		 6cza -
(-) 		5 / 12 LEU A 173
LEU A 522
LEU A 569
ALA A 505
ILE A 147
 None
 1.14A 4x1iD-6czaA:
2.8		 4x1iD-6czaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE5_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 6cza
() 		4 / 6 PRO B 184
ILE A 229
VAL A 745
PHE B 228
 SF4  B 301 ( 4.8A)
None
None
None
 1.13A 4xe5A-6czaB:
undetectable		 4xe5A-6czaB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_B_HFGB802_1
(PROLINE--TRNA LIGASE)		 6cza -
(-) 		3 / 3 GLU A 648
THR A 322
HIS A 323
 None
 0.74A 4ydqB-6czaA:
undetectable		 4ydqB-6czaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4I_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 6cza

(;
) 		3 / 3 VAL B  13
ALA A 260
PHE B 228
 SF4  B 301 (-4.0A)
None
None
 0.57A 4z4iA-6czaB:
undetectable		 4z4iA-6czaB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA303_1
(CHITOSANASE)		 6cza -
(-) 		4 / 5 ASP A 128
VAL A 511
GLY A 818
ALA A 808
 None
 0.87A 5hwaA-6czaA:
undetectable		 5hwaA-6czaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JS1_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 6cza

(;
) 		3 / 3 VAL B  13
ALA A 260
PHE B 228
 SF4  B 301 (-4.0A)
None
None
 0.57A 5js1A-6czaB:
undetectable		 5js1A-6czaB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K9D_A_CE9A402_0
(DIHYDROOROTATE
DEHYDROGENASE
(QUINONE),
MITOCHONDRIAL)		 6cza -
(-) 		5 / 12 ALA A 505
HIS A 506
ALA A 479
PHE A 514
LEU A 498
 None
MGD  A 903 ( 4.4A)
None
None
None
 1.18A 5k9dA-6czaA:
undetectable		 5k9dA-6czaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UAC_C_RFPC3001_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 6cza -
(-) 		5 / 12 ASP B   8
SER B 201
LEU B 193
PRO B 209
ILE B 204
 None
 1.36A 5uacC-6czaB:
undetectable		 5uacC-6czaB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 6cza -
(-) 		3 / 3 ARG B 188
PHE B 223
LEU B  56
 SF4  B 301 (-4.6A)
None
SF4  B 302 ( 4.2A)
 0.73A 5x1bC-6czaB:
undetectable		 5x1bC-6czaB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF9_X_NIOX401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 6cza -
(-) 		5 / 9 LEU A 222
VAL A 252
VAL A 254
LYS A 267
ILE A 349
 None
None
MGD  A 902 (-4.5A)
None
None
 1.19A 5yf9X-6czaA:
undetectable		 5yf9X-6czaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA411_0
(UNCHARACTERIZED
PROTEIN KDOO)		 6cza -
(-) 		3 / 3 LYS B 173
LEU B 175
ARG B 170
 None
 0.91A 5yw0A-6czaB:
undetectable		 5yw0A-6czaB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_A_AQ4A602_1
(CYTOCHROME P450 1A1)		 6cza -
(-) 		4 / 5 ILE A 387
SER A 388
ALA A 694
LEU A 672
 None
 0.93A 6dwnA-6czaA:
undetectable		 6dwnA-6czaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_C_AQ4C602_1
(CYTOCHROME P450 1A1)		 6cza -
(-) 		3 / 3 SER A 191
SER A 841
ALA A 463
 None
 0.65A 6dwnC-6czaA:
undetectable		 6dwnC-6czaA:
undetectable