SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6czm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 6czm -
(-) 		5 / 10 GLY A 252
HIS A 258
THR A 256
ILE A  40
ALA A 242
 None
 1.07A 1gtnU-6czmA:
undetectable
1gtnV-6czmA:
undetectable		 1gtnU-6czmA:
undetectable
1gtnV-6czmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_D_TRPD81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6czm -
(-) 		5 / 9 GLY A 252
THR A 257
HIS A 258
THR A 256
ILE A  40
 None
 1.37A 1utdD-6czmA:
undetectable
1utdE-6czmA:
undetectable		 1utdD-6czmA:
undetectable
1utdE-6czmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_B_CQAB401_0
(HISTAMINE
N-METHYLTRANSFERASE)		 6czm -
(-) 		4 / 7 TRP A  86
GLY A  43
PRO A  90
ASP A  92
 None
 0.94A 2aouB-6czmA:
undetectable		 2aouB-6czmA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FL5_F_RBFF204_1
(IMMUNOGLOBULIN IGG1
LAMBDA LIGHT CHAIN
IMMUNOGLOBULIN IGG1
HEAVY CHAIN)		 6czm -
(-) 		4 / 8 TYR A 321
ASN A 279
ARG A 281
VAL A 309
 None
 1.01A 2fl5E-6czmA:
undetectable
2fl5F-6czmA:
undetectable		 2fl5E-6czmA:
undetectable
2fl5F-6czmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CV9_A_VDXA501_1
(CYTOCHROME P450-SU1)		 6czm -
(-) 		5 / 9 VAL A 233
LEU A 152
ILE A 186
ILE A 210
GLY A 172
 None
 1.22A 3cv9A-6czmA:
undetectable		 3cv9A-6czmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID802_0
(GLUTAMATE RECEPTOR 2)		 6czm -
(-) 		3 / 3 SER A 246
ASP A 121
ASN A 119
 None
 0.96A 3lslA-6czmA:
8.8
3lslD-6czmA:
6.4		 3lslA-6czmA:
23.46
3lslD-6czmA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 6czm -
(-) 		3 / 3 ARG A 269
GLU A 359
THR A 361
 None
 0.69A 3v4tA-6czmA:
0.7		 3v4tA-6czmA:
24.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 6czm -
(-) 		5 / 11 LEU A 333
SER A 336
ILE A 356
VAL A 276
VAL A 292
 None
 1.14A 3w67A-6czmA:
undetectable		 3w67A-6czmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D9H_A_ADNA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 6czm -
(-) 		5 / 11 GLY A 108
VAL A 107
SER A 236
ASP A 110
VAL A 111
 None
 1.26A 4d9hA-6czmA:
undetectable		 4d9hA-6czmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DA6_A_GA2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 6czm -
(-) 		5 / 9 GLY A 108
VAL A 107
SER A 236
ASP A 110
VAL A 111
 None
 1.22A 4da6A-6czmA:
undetectable		 4da6A-6czmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAN_A_2FAA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 6czm -
(-) 		5 / 11 GLY A 108
VAL A 107
SER A 236
ASP A 110
VAL A 111
 None
 1.22A 4danA-6czmA:
undetectable		 4danA-6czmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAN_B_2FAB301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 6czm -
(-) 		5 / 12 GLY A 108
VAL A 107
SER A 236
ASP A 110
VAL A 111
 None
 1.23A 4danA-6czmA:
undetectable
4danB-6czmA:
undetectable		 4danA-6czmA:
undetectable
4danB-6czmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		 6czm -
(-) 		4 / 4 HIS A 126
GLU A 360
HIS A 258
LEU A 371
 None
 1.24A 4m2rA-6czmA:
undetectable		 4m2rA-6czmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 6czm -
(-) 		4 / 6 PHE A 146
MET A 158
ILE A 140
VAL A 189
 None
 1.30A 4mk4B-6czmA:
undetectable		 4mk4B-6czmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6czm -
(-) 		5 / 9 GLY A 252
THR A 257
HIS A 258
THR A 256
ILE A  40
 None
 1.38A 5eeuA-6czmA:
undetectable
5eeuB-6czmA:
undetectable		 5eeuA-6czmA:
undetectable
5eeuB-6czmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6czm -
(-) 		5 / 9 GLY A 252
THR A 257
HIS A 258
THR A 256
ILE A  40
 None
 1.37A 5eeuC-6czmA:
undetectable
5eeuD-6czmA:
undetectable		 5eeuC-6czmA:
undetectable
5eeuD-6czmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6czm -
(-) 		5 / 9 GLY A 252
THR A 257
HIS A 258
THR A 256
ILE A  40
 None
 1.37A 5eevC-6czmA:
undetectable
5eevD-6czmA:
undetectable		 5eevC-6czmA:
undetectable
5eevD-6czmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6czm -
(-) 		5 / 9 GLY A 252
THR A 257
HIS A 258
THR A 256
ILE A  40
 None
 1.37A 5eewC-6czmA:
undetectable
5eewD-6czmA:
undetectable		 5eewC-6czmA:
undetectable
5eewD-6czmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6czm -
(-) 		5 / 9 GLY A 252
THR A 257
HIS A 258
THR A 256
ILE A  40
 None
 1.37A 5eexC-6czmA:
undetectable
5eexD-6czmA:
undetectable		 5eexC-6czmA:
undetectable
5eexD-6czmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6czm -
(-) 		5 / 9 GLY A 252
THR A 257
HIS A 258
THR A 256
ILE A  40
 None
 1.37A 5eeyC-6czmA:
undetectable
5eeyD-6czmA:
undetectable		 5eeyC-6czmA:
undetectable
5eeyD-6czmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6czm -
(-) 		5 / 9 GLY A 252
THR A 257
HIS A 258
THR A 256
ILE A  40
 None
 1.37A 5eezC-6czmA:
undetectable
5eezD-6czmA:
undetectable		 5eezC-6czmA:
undetectable
5eezD-6czmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6czm -
(-) 		5 / 9 GLY A 252
THR A 257
HIS A 258
THR A 256
ILE A  40
 None
 1.36A 5ef0C-6czmA:
undetectable
5ef0D-6czmA:
undetectable		 5ef0C-6czmA:
undetectable
5ef0D-6czmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6czm -
(-) 		5 / 9 GLY A 252
THR A 257
HIS A 258
THR A 256
ILE A  40
 None
 1.36A 5ef1C-6czmA:
undetectable
5ef1D-6czmA:
undetectable		 5ef1C-6czmA:
undetectable
5ef1D-6czmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6czm -
(-) 		5 / 9 GLY A 252
THR A 257
HIS A 258
THR A 256
ILE A  40
 None
 1.37A 5ef2C-6czmA:
undetectable
5ef2D-6czmA:
undetectable		 5ef2C-6czmA:
undetectable
5ef2D-6czmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6czm -
(-) 		5 / 9 GLY A 252
THR A 257
HIS A 258
THR A 256
ILE A  40
 None
 1.36A 5ef3C-6czmA:
undetectable
5ef3D-6czmA:
undetectable		 5ef3C-6czmA:
undetectable
5ef3D-6czmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUI_B_CTCB405_0
(TETRACYCLINE
DESTRUCTASE TET(50))		 6czm -
(-) 		5 / 12 VAL A 107
LEU A 264
PRO A  45
VAL A  85
ILE A  77
 None
 1.44A 5tuiB-6czmA:
undetectable		 5tuiB-6czmA:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCY_A_DB8A401_2
(MEMBRANE-ASSOCIATED
TYROSINE- AND
THREONINE-SPECIFIC
CDC2-INHIBITORY
KINASE)		 6czm -
(-) 		4 / 4 VAL A  94
LEU A 109
ASN A 119
ASP A 121
 None
 1.35A 5vcyA-6czmA:
undetectable		 5vcyA-6czmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_2
(CARBONIC ANHYDRASE 2)		 6czm -
(-) 		4 / 5 HIS A 126
GLU A 360
HIS A 258
LEU A 371
 None
 1.21A 6bc9A-6czmA:
undetectable		 6bc9A-6czmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_A_HISA402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 6czm -
(-) 		5 / 10 GLY A 300
LEU A 301
THR A 305
VAL A 325
CYH A 327
 HIS  A 402 (-3.4A)
HIS  A 402 (-4.0A)
HIS  A 402 (-4.2A)
HIS  A 402 (-4.4A)
HIS  A 402 (-4.2A)
 0.00A 6czmA-6czmA:
46.0
6czmC-6czmA:
41.8		 6czmA-6czmA:
undetectable
6czmC-6czmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_A_HISA402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 6czm -
(-) 		5 / 10 VAL A 277
ASN A 279
VAL A 309
ALA A 323
LEU A 349
 None
 0.10A 6czmA-6czmA:
46.0
6czmC-6czmA:
41.8		 6czmA-6czmA:
undetectable
6czmC-6czmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_B_HISB402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 6czm -
(-) 		5 / 9 GLY A 300
LEU A 301
GLN A 302
THR A 305
VAL A 325
 HIS  A 402 (-3.4A)
HIS  A 402 (-4.0A)
None
HIS  A 402 (-4.2A)
HIS  A 402 (-4.4A)
 0.52A 6czmA-6czmA:
46.0
6czmB-6czmA:
37.0		 6czmA-6czmA:
undetectable
6czmB-6czmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_C_HISC402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 6czm -
(-) 		5 / 9 GLY A 300
LEU A 301
GLN A 302
THR A 305
VAL A 325
 HIS  A 402 (-3.4A)
HIS  A 402 (-4.0A)
None
HIS  A 402 (-4.2A)
HIS  A 402 (-4.4A)
 0.58A 6czmB-6czmA:
37.0
6czmC-6czmA:
41.8		 6czmB-6czmA:
undetectable
6czmC-6czmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_E_HISE402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 6czm -
(-) 		5 / 9 GLY A 300
LEU A 301
THR A 305
VAL A 325
CYH A 327
 HIS  A 402 (-3.4A)
HIS  A 402 (-4.0A)
HIS  A 402 (-4.2A)
HIS  A 402 (-4.4A)
HIS  A 402 (-4.2A)
 0.23A 6czmD-6czmA:
41.2
6czmE-6czmA:
42.8		 6czmD-6czmA:
undetectable
6czmE-6czmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_F_HISF402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 6czm -
(-) 		6 / 10 GLY A 300
LEU A 301
GLN A 302
THR A 305
VAL A 325
CYH A 327
 HIS  A 402 (-3.4A)
HIS  A 402 (-4.0A)
None
HIS  A 402 (-4.2A)
HIS  A 402 (-4.4A)
HIS  A 402 (-4.2A)
 0.24A 6czmE-6czmA:
42.8
6czmF-6czmA:
37.6		 6czmE-6czmA:
undetectable
6czmF-6czmA:
undetectable