SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6czp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GMK_A_DVAA8_0 (GRAMICIDIN A)	6czp	OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE (Vibrio vulnificus)	3 / 4	VAL A 143 TRP A 138 TRP A 46	None	1.36A	1gmkA-6czpA: undetectable 1gmkB-6czpA: undetectable	1gmkA-6czpA: undetectable 1gmkB-6czpA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HK3_A_T44A3003_1 (SERUM ALBUMIN)	6czp	OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE (Vibrio vulnificus)	3 / 4	LYS A 26 ALA A 29 MET A 157	None	0.76A	1hk3A-6czpA: 4.4	1hk3A-6czpA: 9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OIP_A_VIVA1278_1 (ALPHA-TOCOPHEROL TRANSFER PROTEIN)	6czp	OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE (Vibrio vulnificus)	4 / 5	SER A 43 SER A 40 VAL A 125 PHE A 124	None	1.44A	1oipA-6czpA: undetectable	1oipA-6czpA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RB3_A_MTXA161_1 (DIHYDROFOLATE REDUCTASE)	6czp	OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE (Vibrio vulnificus)	5 / 10	ALA A 169 ASP A 173 LEU A 178 ARG A 59 ILE A 60	None	1.30A	1rb3A-6czpA: undetectable	1rb3A-6czpA: 15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YKI_A_NFZA1219_1 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	6czp	OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE (Vibrio vulnificus)	4 / 8	ASN A 71 LYS A 74 GLU A 165 GLY A 166	FMN A 301 (-3.1A) FMN A 301 (-2.9A) FMN A 301 (-3.5A) FMN A 301 (-3.3A)	0.74A	1ykiA-6czpA: 32.0 1ykiB-6czpA: 31.8	1ykiA-6czpA: 27.75 1ykiB-6czpA: 27.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YKI_B_NFZB2219_1 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	6czp	OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE (Vibrio vulnificus)	4 / 8	ASN A 71 LYS A 74 GLU A 165 GLY A 166	FMN A 301 (-3.1A) FMN A 301 (-2.9A) FMN A 301 (-3.5A) FMN A 301 (-3.3A)	0.77A	1ykiA-6czpA: 32.0 1ykiB-6czpA: 31.8	1ykiA-6czpA: 27.75 1ykiB-6czpA: 27.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YKI_C_NFZC3219_1 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	6czp	OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE (Vibrio vulnificus)	4 / 8	ASN A 71 LYS A 74 GLU A 165 GLY A 166	FMN A 301 (-3.1A) FMN A 301 (-2.9A) FMN A 301 (-3.5A) FMN A 301 (-3.3A)	0.78A	1ykiC-6czpA: 31.9 1ykiD-6czpA: 31.9	1ykiC-6czpA: 27.75 1ykiD-6czpA: 27.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YKI_D_NFZD4219_1 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	6czp	OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE (Vibrio vulnificus)	4 / 8	ASN A 71 LYS A 74 GLU A 165 GLY A 166	FMN A 301 (-3.1A) FMN A 301 (-2.9A) FMN A 301 (-3.5A) FMN A 301 (-3.3A)	0.73A	1ykiC-6czpA: 31.9 1ykiD-6czpA: 31.9	1ykiC-6czpA: 27.75 1ykiD-6czpA: 27.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JWA_A_ACTA609_0 (NADH DEHYDROGENASE, PUTATIVE)	6czp	OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE (Vibrio vulnificus)	3 / 3	VAL A 213 SER A 209 TRP A 208	None	0.78A	5jwaA-6czpA: undetectable	5jwaA-6czpA: undetectable

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1GMK_A_DVAA8_0","GRAMICIDIN A","6czp","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","Vibrio vulnificus",3,"VAL A 143;TRP A 138;TRP A  46","None","1.36A","1gmkA-6czpA:undetectable;1gmkB-6czpA:undetectable","1gmkA-6czpA:undetectable;1gmkB-6czpA:undetectable"],["1HK3_A_T44A3003_1","SERUM ALBUMIN","6czp","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","Vibrio vulnificus",3,"LYS A  26;ALA A  29;MET A 157","None","0.76A","1hk3A-6czpA:4.4","1hk3A-6czpA:9.09"],["1OIP_A_VIVA1278_1","ALPHA-TOCOPHEROL TRANSFER PROTEIN","6czp","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","Vibrio vulnificus",4,"SER A  43;SER A  40;VAL A 125;PHE A 124","None","1.44A","1oipA-6czpA:undetectable","1oipA-6czpA:undetectable"],["1RB3_A_MTXA161_1","DIHYDROFOLATE REDUCTASE","6czp","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","Vibrio vulnificus",5,"ALA A 169;ASP A 173;LEU A 178;ARG A  59;ILE A  60","None","1.30A","1rb3A-6czpA:undetectable","1rb3A-6czpA:15.92"],["1YKI_A_NFZA1219_1","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE;OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","6czp","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","Vibrio vulnificus",4,"ASN A  71;LYS A  74;GLU A 165;GLY A 166","FMN A 301 (-3.1A);FMN A 301 (-2.9A);FMN A 301 (-3.5A);FMN A 301 (-3.3A)","0.74A","1ykiA-6czpA:32.0;1ykiB-6czpA:31.8","1ykiA-6czpA:27.75;1ykiB-6czpA:27.75"],["1YKI_B_NFZB2219_1","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE;OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","6czp","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","Vibrio vulnificus",4,"ASN A  71;LYS A  74;GLU A 165;GLY A 166","FMN A 301 (-3.1A);FMN A 301 (-2.9A);FMN A 301 (-3.5A);FMN A 301 (-3.3A)","0.77A","1ykiA-6czpA:32.0;1ykiB-6czpA:31.8","1ykiA-6czpA:27.75;1ykiB-6czpA:27.75"],["1YKI_C_NFZC3219_1","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE;OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","6czp","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","Vibrio vulnificus",4,"ASN A  71;LYS A  74;GLU A 165;GLY A 166","FMN A 301 (-3.1A);FMN A 301 (-2.9A);FMN A 301 (-3.5A);FMN A 301 (-3.3A)","0.78A","1ykiC-6czpA:31.9;1ykiD-6czpA:31.9","1ykiC-6czpA:27.75;1ykiD-6czpA:27.75"],["1YKI_D_NFZD4219_1","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE;OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","6czp","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","Vibrio vulnificus",4,"ASN A  71;LYS A  74;GLU A 165;GLY A 166","FMN A 301 (-3.1A);FMN A 301 (-2.9A);FMN A 301 (-3.5A);FMN A 301 (-3.3A)","0.73A","1ykiC-6czpA:31.9;1ykiD-6czpA:31.9","1ykiC-6czpA:27.75;1ykiD-6czpA:27.75"],["5JWA_A_ACTA609_0","NADH DEHYDROGENASE, PUTATIVE","6czp","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","Vibrio vulnificus",3,"VAL A 213;SER A 209;TRP A 208","None","0.78A","5jwaA-6czpA:undetectable","5jwaA-6czpA:undetectable"]]