SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6d0g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTJ_A_THRA401_0
(ASPARTOKINASE)		 6d0g PIRIN FAMILY PROTEIN
(Acinetobacter
baumannii) 		4 / 8 ASP A 142
GLY A  80
ALA A 139
ILE A 263
 None
 0.67A 2dtjA-6d0gA:
undetectable
2dtjB-6d0gA:
undetectable		 2dtjA-6d0gA:
undetectable
2dtjB-6d0gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_A_SAMA300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 6d0g PIRIN FAMILY PROTEIN
(Acinetobacter
baumannii) 		3 / 3 SER A  45
HIS A  59
ASP A 191
 None
 0.78A 2oxtA-6d0gA:
undetectable		 2oxtA-6d0gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_B_RIMB299_1
(MATRIX PROTEIN 2)		 6d0g PIRIN FAMILY PROTEIN
(Acinetobacter
baumannii) 		4 / 6 LEU A 204
LEU A 238
ILE A 202
ARG A 201
 None
 1.09A 2rlfB-6d0gA:
undetectable
2rlfC-6d0gA:
undetectable		 2rlfB-6d0gA:
21.33
2rlfC-6d0gA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZSF_A_ACTA803_0
(PANTOTHENATE KINASE)		 6d0g PIRIN FAMILY PROTEIN
(Acinetobacter
baumannii) 		4 / 4 ARG A 290
PRO A 149
GLY A 115
HIS A 116
 None
 1.39A 2zsfA-6d0gA:
0.0		 2zsfA-6d0gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_B_ECNB602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 6d0g PIRIN FAMILY PROTEIN
(Acinetobacter
baumannii) 		5 / 9 PHE A  65
GLY A  61
ALA A 133
THR A  85
ILE A 104
 None
 1.27A 3jusB-6d0gA:
undetectable		 3jusB-6d0gA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_C_STRC601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 6d0g PIRIN FAMILY PROTEIN
(Acinetobacter
baumannii) 		4 / 5 ILE A 193
ASP A 163
GLU A 166
VAL A 190
 None
 1.24A 4nkxC-6d0gA:
undetectable		 4nkxC-6d0gA:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		 6d0g PIRIN FAMILY PROTEIN
(Acinetobacter
baumannii) 		5 / 12 GLY A 189
VAL A 181
LEU A 157
ASN A 110
PHE A  84
 None
 1.01A 4pd5A-6d0gA:
undetectable		 4pd5A-6d0gA:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H8T_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 6d0g PIRIN FAMILY PROTEIN
(Acinetobacter
baumannii) 		5 / 12 LEU A  57
ALA A 134
ILE A 243
ILE A 254
LEU A 226
 None
 1.13A 5h8tA-6d0gA:
undetectable		 5h8tA-6d0gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 6d0g PIRIN FAMILY PROTEIN
(Acinetobacter
baumannii) 		4 / 7 LEU A 157
GLU A 173
ILE A 138
VAL A 171
 None
 1.16A 5jh7C-6d0gA:
undetectable		 5jh7C-6d0gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MTH_A_ACTA301_0
(ANTIBODY FAB HEAVY
CHAIN)		 6d0g PIRIN FAMILY PROTEIN
(Acinetobacter
baumannii) 		4 / 4 THR A  95
VAL A 123
PRO A  75
THR A 121
 None
 1.39A 5mthA-6d0gA:
1.9
5mthH-6d0gA:
undetectable		 5mthA-6d0gA:
undetectable
5mthH-6d0gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA607_0
(TYROSINASE)		 6d0g PIRIN FAMILY PROTEIN
(Acinetobacter
baumannii) 		3 / 3 HIS A  76
HIS A 120
HIS A  78
 MN  A 401 (-3.4A)
MN  A 401 (-3.4A)
MN  A 401 (-3.5A)
 0.58A 5zrdA-6d0gA:
undetectable		 5zrdA-6d0gA:
undetectable