SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6d0p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA355_1
(PROTEIN (ADENOSINE
KINASE))		 6d0p PIRIN FAMILY PROTEIN
(Acinetobacter
baumannii) 		5 / 12 VAL A  69
ALA A 173
GLY A 172
ALA A 174
ILE A 143
 None
 0.93A 1bx4A-6d0pA:
undetectable		 1bx4A-6d0pA:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_A_H4BA1003_1
(HYPOTHETICAL PROTEIN
PH0634)		 6d0p PIRIN FAMILY PROTEIN
(Acinetobacter
baumannii) 		5 / 10 HIS A  61
HIS A  63
HIS A 105
GLU A 107
PHE A  20
 MN  A 303 ( 3.3A)
MN  A 303 (-3.4A)
MN  A 303 (-3.4A)
MN  A 303 ( 2.9A)
PEG  A 304 ( 4.2A)
 1.29A 2dttA-6d0pA:
undetectable
2dttC-6d0pA:
undetectable		 2dttA-6d0pA:
19.13
2dttC-6d0pA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_E_H4BE1004_1
(HYPOTHETICAL PROTEIN
PH0634)		 6d0p PIRIN FAMILY PROTEIN
(Acinetobacter
baumannii) 		5 / 11 PHE A  20
HIS A  61
HIS A  63
HIS A 105
GLU A 107
 PEG  A 304 ( 4.2A)
MN  A 303 ( 3.3A)
MN  A 303 (-3.4A)
MN  A 303 (-3.4A)
MN  A 303 ( 2.9A)
 1.24A 2dttD-6d0pA:
undetectable
2dttE-6d0pA:
undetectable		 2dttD-6d0pA:
19.13
2dttE-6d0pA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZV_A_AZMA263_1
(CARBONIC ANHYDRASE
13)		 6d0p PIRIN FAMILY PROTEIN
(Acinetobacter
baumannii) 		5 / 12 HIS A  61
HIS A  63
HIS A 105
THR A  68
VAL A  22
 MN  A 303 ( 3.3A)
MN  A 303 (-3.4A)
MN  A 303 (-3.4A)
MN  A 303 ( 4.9A)
None
 1.14A 3czvA-6d0pA:
undetectable
3czvB-6d0pA:
undetectable		 3czvA-6d0pA:
18.75
3czvB-6d0pA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_B_TRPB1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 6d0p PIRIN FAMILY PROTEIN
(Acinetobacter
baumannii) 		4 / 8 VAL A 127
ILE A 163
VAL A  94
GLN A 141
 None
 0.78A 3fi0B-6d0pA:
undetectable		 3fi0B-6d0pA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 6d0p PIRIN FAMILY PROTEIN
(Acinetobacter
baumannii) 		4 / 7 VAL A 127
ILE A 163
VAL A  94
GLN A 141
 None
 0.87A 3fi0E-6d0pA:
undetectable		 3fi0E-6d0pA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FZG_A_SAMA300_0
(16S RRNA METHYLASE)		 6d0p PIRIN FAMILY PROTEIN
(Acinetobacter
baumannii) 		5 / 12 HIS A  79
THR A  78
GLY A  85
GLY A  87
VAL A 103
 None
 1.29A 3fzgA-6d0pA:
undetectable		 3fzgA-6d0pA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NVK_I_SAMI228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 6d0p PIRIN FAMILY PROTEIN
(Acinetobacter
baumannii) 		5 / 12 GLY A 172
ALA A 174
THR A 176
ALA A 170
VAL A 162
 None
 1.10A 3nvkI-6d0pA:
undetectable		 3nvkI-6d0pA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PFG_A_SAMA264_0
(N-METHYLTRANSFERASE)		 6d0p PIRIN FAMILY PROTEIN
(Acinetobacter
baumannii) 		5 / 12 ALA A  99
GLY A  65
MET A 135
MET A  97
PHE A 263
 None
 1.39A 3pfgA-6d0pA:
undetectable		 3pfgA-6d0pA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 6d0p PIRIN FAMILY PROTEIN
(Acinetobacter
baumannii) 		4 / 8 ILE A 148
ASP A 147
ILE A 143
VAL A  69
 None
 0.81A 4acaC-6d0pA:
undetectable		 4acaC-6d0pA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 6d0p PIRIN FAMILY PROTEIN
(Acinetobacter
baumannii) 		4 / 8 ILE A 148
ASP A 147
ILE A 143
VAL A  69
 None
 0.79A 4acbC-6d0pA:
undetectable		 4acbC-6d0pA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_B_ECNB403_1
(FLAVOHEMOGLOBIN)		 6d0p PIRIN FAMILY PROTEIN
(Acinetobacter
baumannii) 		5 / 11 ILE A  71
GLN A 141
ALA A 174
VAL A 182
LEU A 125
 None
 1.12A 4g1bB-6d0pA:
undetectable		 4g1bB-6d0pA:
9.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KT0_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 6d0p PIRIN FAMILY PROTEIN
(Acinetobacter
baumannii) 		5 / 11 PHE A 120
GLY A 118
GLY A  75
ILE A 286
LEU A 104
 None
 1.12A 4kt0A-6d0pA:
undetectable
4kt0J-6d0pA:
undetectable		 4kt0A-6d0pA:
7.77
4kt0J-6d0pA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L78_A_ACTA1327_0
(PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE)		 6d0p PIRIN FAMILY PROTEIN
(Acinetobacter
baumannii) 		4 / 4 VAL A  77
THR A  78
GLU A 107
GLU A 106
 None
None
MN  A 303 ( 2.9A)
MG  A 301 ( 4.0A)
 1.40A 4l78A-6d0pA:
undetectable		 4l78A-6d0pA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WRY_A_URFA302_1
(URACIL-DNA
GLYCOSYLASE)		 6d0p PIRIN FAMILY PROTEIN
(Acinetobacter
baumannii) 		4 / 8 GLY A  57
GLN A  56
PHE A  20
HIS A 109
 None
None
PEG  A 304 ( 4.2A)
None
 0.87A 4wryA-6d0pA:
undetectable		 4wryA-6d0pA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WRZ_A_URFA302_1
(URACIL-DNA
GLYCOSYLASE)		 6d0p PIRIN FAMILY PROTEIN
(Acinetobacter
baumannii) 		4 / 8 GLY A  57
GLN A  56
PHE A  20
HIS A 109
 None
None
PEG  A 304 ( 4.2A)
None
 0.86A 4wrzA-6d0pA:
undetectable		 4wrzA-6d0pA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_B_AZMB402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 6d0p PIRIN FAMILY PROTEIN
(Acinetobacter
baumannii) 		5 / 12 HIS A 105
GLU A 107
HIS A  61
THR A  68
VAL A 264
 MN  A 303 (-3.4A)
MN  A 303 ( 2.9A)
MN  A 303 ( 3.3A)
MN  A 303 ( 4.9A)
None
 1.03A 4xiwB-6d0pA:
undetectable
4xiwE-6d0pA:
undetectable		 4xiwB-6d0pA:
15.90
4xiwE-6d0pA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_A_VDYA201_2
(CDL2.2)		 6d0p PIRIN FAMILY PROTEIN
(Acinetobacter
baumannii) 		5 / 12 PRO A 198
LEU A 237
LEU A 160
PRO A 149
LEU A 228
 None
 0.97A 5ienA-6d0pA:
undetectable		 5ienA-6d0pA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_H_SAMH501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 6d0p PIRIN FAMILY PROTEIN
(Acinetobacter
baumannii) 		5 / 10 LEU A 208
GLY A 222
LEU A 246
VAL A 205
THR A 224
 None
 1.02A 5o96G-6d0pA:
undetectable
5o96H-6d0pA:
undetectable		 5o96G-6d0pA:
undetectable
5o96H-6d0pA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OHH_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 6d0p PIRIN FAMILY PROTEIN
(Acinetobacter
baumannii) 		4 / 5 HIS A  61
HIS A  63
VAL A 103
THR A  68
 MN  A 303 ( 3.3A)
MN  A 303 (-3.4A)
None
MN  A 303 ( 4.9A)
 1.36A 5ohhA-6d0pA:
undetectable		 5ohhA-6d0pA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA607_0
(TYROSINASE)		 6d0p PIRIN FAMILY PROTEIN
(Acinetobacter
baumannii) 		3 / 3 HIS A  61
HIS A 105
HIS A  63
 MN  A 303 ( 3.3A)
MN  A 303 (-3.4A)
MN  A 303 (-3.4A)
 0.52A 5zrdA-6d0pA:
undetectable		 5zrdA-6d0pA:
undetectable