SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6d14'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3003_1
(SERUM ALBUMIN)		 6d14 TNF
RECEPTOR-ASSOCIATED
PROTEIN 1
(Danio
rerio) 		4 / 6 HIS A 663
ILE A 666
LYS A 673
ALA A 680
 None
 1.01A 1hk1A-6d14A:
undetectable		 1hk1A-6d14A:
9.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHA_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 6d14 TNF
RECEPTOR-ASSOCIATED
PROTEIN 1
(Danio
rerio) 		4 / 8 GLY A 188
GLY A 250
LEU A 113
SER A 248
 None
 0.77A 1jhaA-6d14A:
undetectable		 1jhaA-6d14A:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_ACTC2294_0
(GLYCINE
N-METHYLTRANSFERASE)		 6d14 TNF
RECEPTOR-ASSOCIATED
PROTEIN 1
(Danio
rerio) 		4 / 7 TRP A 314
TYR A 381
ASN A 294
TYR A 332
 None
 1.43A 1kiaC-6d14A:
undetectable		 1kiaC-6d14A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_D_ACTD3294_0
(GLYCINE
N-METHYLTRANSFERASE)		 6d14 TNF
RECEPTOR-ASSOCIATED
PROTEIN 1
(Danio
rerio) 		4 / 7 TRP A 314
TYR A 381
ASN A 294
TYR A 332
 None
 1.44A 1kiaD-6d14A:
undetectable		 1kiaD-6d14A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_B_ACTB1294_0
(GLYCINE
N-METHYLTRANSFERASE)		 6d14 TNF
RECEPTOR-ASSOCIATED
PROTEIN 1
(Danio
rerio) 		4 / 7 TRP A 314
TYR A 381
ASN A 294
TYR A 332
 None
 1.43A 1nbhB-6d14A:
undetectable		 1nbhB-6d14A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_ACTD3294_0
(GLYCINE
N-METHYLTRANSFERASE)		 6d14 TNF
RECEPTOR-ASSOCIATED
PROTEIN 1
(Danio
rerio) 		4 / 7 TRP A 314
TYR A 381
ASN A 294
TYR A 332
 None
 1.43A 1nbhD-6d14A:
undetectable		 1nbhD-6d14A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 6d14 TNF
RECEPTOR-ASSOCIATED
PROTEIN 1
(Danio
rerio) 		4 / 7 LEU A 598
HIS A 525
THR A 615
HIS A 521
 None
 1.15A 1v55C-6d14A:
undetectable
1v55N-6d14A:
undetectable
1v55P-6d14A:
undetectable		 1v55C-6d14A:
undetectable
1v55N-6d14A:
undetectable
1v55P-6d14A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_A_9CRA502_1
(CYTOCHROME P450 2C8)		 6d14 TNF
RECEPTOR-ASSOCIATED
PROTEIN 1
(Danio
rerio) 		5 / 12 ILE A 426
ILE A 394
LEU A 420
ASN A 414
VAL A 406
 None
 1.05A 2nnhA-6d14A:
undetectable		 2nnhA-6d14A:
10.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1001_0
(ALDEHYDE
DEHYDROGENASE A)		 6d14 TNF
RECEPTOR-ASSOCIATED
PROTEIN 1
(Danio
rerio) 		4 / 7 LEU A 270
ILE A 268
ASN A 134
PHE A 220
 None
None
ANP  A 801 (-2.7A)
None
 0.88A 2opxA-6d14A:
undetectable		 2opxA-6d14A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRL_A_DXTA1211_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 6d14 TNF
RECEPTOR-ASSOCIATED
PROTEIN 1
(Danio
rerio) 		5 / 12 PHE A 636
THR A 610
VAL A 609
LEU A 657
ILE A 625
 None
 1.21A 2xrlA-6d14A:
undetectable		 2xrlA-6d14A:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6d14 TNF
RECEPTOR-ASSOCIATED
PROTEIN 1
(Danio
rerio) 		4 / 8 HIS A 525
THR A 615
HIS A 521
LEU A 598
 None
 1.08A 3ablA-6d14A:
undetectable
3ablC-6d14A:
undetectable
3ablP-6d14A:
undetectable		 3ablA-6d14A:
undetectable
3ablC-6d14A:
undetectable
3ablP-6d14A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6d14 TNF
RECEPTOR-ASSOCIATED
PROTEIN 1
(Danio
rerio) 		4 / 8 LEU A 598
HIS A 525
THR A 615
HIS A 521
 None
 1.11A 3ablC-6d14A:
undetectable
3ablN-6d14A:
undetectable
3ablP-6d14A:
undetectable		 3ablC-6d14A:
undetectable
3ablN-6d14A:
undetectable
3ablP-6d14A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6d14 TNF
RECEPTOR-ASSOCIATED
PROTEIN 1
(Danio
rerio) 		4 / 8 HIS A 525
THR A 615
HIS A 521
LEU A 598
 None
 1.12A 3abmA-6d14A:
undetectable
3abmC-6d14A:
undetectable
3abmP-6d14A:
undetectable		 3abmA-6d14A:
undetectable
3abmC-6d14A:
undetectable
3abmP-6d14A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6d14 TNF
RECEPTOR-ASSOCIATED
PROTEIN 1
(Danio
rerio) 		4 / 8 LEU A 598
HIS A 525
THR A 615
HIS A 521
 None
 1.15A 3asnC-6d14A:
undetectable
3asnN-6d14A:
undetectable
3asnP-6d14A:
undetectable		 3asnC-6d14A:
undetectable
3asnN-6d14A:
undetectable
3asnP-6d14A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6d14 TNF
RECEPTOR-ASSOCIATED
PROTEIN 1
(Danio
rerio) 		4 / 8 HIS A 525
THR A 615
HIS A 521
LEU A 598
 None
 1.16A 3asoA-6d14A:
undetectable
3asoC-6d14A:
undetectable
3asoP-6d14A:
undetectable		 3asoA-6d14A:
undetectable
3asoC-6d14A:
undetectable
3asoP-6d14A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6d14 TNF
RECEPTOR-ASSOCIATED
PROTEIN 1
(Danio
rerio) 		4 / 8 LEU A 598
HIS A 525
THR A 615
HIS A 521
 None
 1.15A 3asoC-6d14A:
undetectable
3asoN-6d14A:
undetectable
3asoP-6d14A:
undetectable		 3asoC-6d14A:
undetectable
3asoN-6d14A:
undetectable
3asoP-6d14A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_3
(PHOSPHOLIPASE A2)		 6d14 TNF
RECEPTOR-ASSOCIATED
PROTEIN 1
(Danio
rerio) 		3 / 3 PRO A 449
PHE A 455
LYS A 451
 None
 1.26A 3bjwG-6d14A:
undetectable		 3bjwG-6d14A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_A_V2HA602_0
(CYTOCHROME P450 2R1)		 6d14 TNF
RECEPTOR-ASSOCIATED
PROTEIN 1
(Danio
rerio) 		5 / 12 THR A 162
PHE A 127
VAL A 226
VAL A 296
ILE A 300
 None
 1.20A 3dl9A-6d14A:
undetectable		 3dl9A-6d14A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PO7_A_ZONA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 6d14 TNF
RECEPTOR-ASSOCIATED
PROTEIN 1
(Danio
rerio) 		4 / 8 TYR A 381
LEU A 310
TYR A 332
PHE A 329
 None
 1.24A 3po7A-6d14A:
undetectable		 3po7A-6d14A:
9.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6d14 TNF
RECEPTOR-ASSOCIATED
PROTEIN 1
(Danio
rerio) 		4 / 8 HIS A 525
THR A 615
HIS A 521
LEU A 598
 None
 1.13A 3wg7A-6d14A:
2.7
3wg7C-6d14A:
undetectable
3wg7P-6d14A:
undetectable		 3wg7A-6d14A:
undetectable
3wg7C-6d14A:
undetectable
3wg7P-6d14A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6d14 TNF
RECEPTOR-ASSOCIATED
PROTEIN 1
(Danio
rerio) 		4 / 8 LEU A 598
HIS A 525
THR A 615
HIS A 521
 None
 1.10A 3wg7C-6d14A:
undetectable
3wg7N-6d14A:
undetectable
3wg7P-6d14A:
undetectable		 3wg7C-6d14A:
undetectable
3wg7N-6d14A:
undetectable
3wg7P-6d14A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6d14 TNF
RECEPTOR-ASSOCIATED
PROTEIN 1
(Danio
rerio) 		4 / 8 HIS A 525
THR A 615
HIS A 521
LEU A 598
 None
 1.09A 3x2qA-6d14A:
undetectable
3x2qC-6d14A:
undetectable
3x2qP-6d14A:
undetectable		 3x2qA-6d14A:
undetectable
3x2qC-6d14A:
undetectable
3x2qP-6d14A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP308_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6d14 TNF
RECEPTOR-ASSOCIATED
PROTEIN 1
(Danio
rerio) 		4 / 8 LEU A 598
HIS A 525
THR A 615
HIS A 521
 None
 1.14A 3x2qC-6d14A:
undetectable
3x2qN-6d14A:
undetectable
3x2qP-6d14A:
undetectable		 3x2qC-6d14A:
undetectable
3x2qN-6d14A:
undetectable
3x2qP-6d14A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_B_ADNB501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 6d14 TNF
RECEPTOR-ASSOCIATED
PROTEIN 1
(Danio
rerio) 		3 / 3 PRO A 491
LEU A 490
GLN A 495
 None
 0.64A 4pevB-6d14A:
undetectable		 4pevB-6d14A:
11.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_F_377F401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 6d14 TNF
RECEPTOR-ASSOCIATED
PROTEIN 1
(Danio
rerio) 		4 / 7 GLU A 629
TYR A 528
LEU A 515
ARG A 634
 None
 1.22A 4twdF-6d14A:
2.7
4twdJ-6d14A:
undetectable		 4twdF-6d14A:
15.36
4twdJ-6d14A:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_G_377G401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 6d14 TNF
RECEPTOR-ASSOCIATED
PROTEIN 1
(Danio
rerio) 		4 / 6 ARG A 634
GLU A 629
TYR A 528
LEU A 515
 None
 1.11A 4twdF-6d14A:
2.7
4twdG-6d14A:
1.6		 4twdF-6d14A:
15.36
4twdG-6d14A:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_ADNA2414_1
(RNA-DIRECTED RNA
POLYMERASE L)		 6d14 TNF
RECEPTOR-ASSOCIATED
PROTEIN 1
(Danio
rerio) 		4 / 6 GLU A 457
PHE A 456
ARG A 341
TYR A 459
 None
 1.30A 4uciA-6d14A:
undetectable		 4uciA-6d14A:
13.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_ADNB2415_1
(RNA-DIRECTED RNA
POLYMERASE L)		 6d14 TNF
RECEPTOR-ASSOCIATED
PROTEIN 1
(Danio
rerio) 		4 / 7 GLU A 457
PHE A 456
ARG A 341
TYR A 459
 None
 1.30A 4uciB-6d14A:
undetectable		 4uciB-6d14A:
13.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6d14 TNF
RECEPTOR-ASSOCIATED
PROTEIN 1
(Danio
rerio) 		4 / 8 HIS A 525
THR A 615
HIS A 521
LEU A 598
 None
 1.14A 5b1aA-6d14A:
undetectable
5b1aC-6d14A:
undetectable
5b1aP-6d14A:
undetectable		 5b1aA-6d14A:
undetectable
5b1aC-6d14A:
undetectable
5b1aP-6d14A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6d14 TNF
RECEPTOR-ASSOCIATED
PROTEIN 1
(Danio
rerio) 		4 / 8 HIS A 525
THR A 615
HIS A 521
LEU A 598
 None
 1.13A 5b3sA-6d14A:
3.0
5b3sC-6d14A:
undetectable
5b3sP-6d14A:
undetectable		 5b3sA-6d14A:
undetectable
5b3sC-6d14A:
undetectable
5b3sP-6d14A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESK_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 6d14 TNF
RECEPTOR-ASSOCIATED
PROTEIN 1
(Danio
rerio) 		4 / 4 ALA A 154
PRO A 299
LEU A 160
HIS A 159
 None
 1.35A 5eskA-6d14A:
undetectable		 5eskA-6d14A:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_F_FK5F201_1
(FK506-BINDING
PROTEIN 1)		 6d14 TNF
RECEPTOR-ASSOCIATED
PROTEIN 1
(Danio
rerio) 		5 / 12 VAL A 288
ILE A 300
ILE A 158
PHE A 169
ILE A 213
 None
 1.03A 5hw8B-6d14A:
undetectable
5hw8F-6d14A:
undetectable
5hw8G-6d14A:
undetectable		 5hw8B-6d14A:
19.51
5hw8F-6d14A:
19.51
5hw8G-6d14A:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6d14 TNF
RECEPTOR-ASSOCIATED
PROTEIN 1
(Danio
rerio) 		4 / 8 LEU A 598
HIS A 525
THR A 615
HIS A 521
 None
 1.10A 5iy5C-6d14A:
undetectable
5iy5N-6d14A:
undetectable
5iy5P-6d14A:
undetectable		 5iy5C-6d14A:
undetectable
5iy5N-6d14A:
undetectable
5iy5P-6d14A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_H_RITH602_2
(CYTOCHROME P450 3A5)		 6d14 TNF
RECEPTOR-ASSOCIATED
PROTEIN 1
(Danio
rerio) 		4 / 5 ARG A 464
PHE A 456
LEU A 482
LEU A 540
 None
 1.25A 5veuH-6d14A:
undetectable		 5veuH-6d14A:
10.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6d14 TNF
RECEPTOR-ASSOCIATED
PROTEIN 1
(Danio
rerio) 		4 / 8 HIS A 525
THR A 615
HIS A 521
LEU A 598
 None
 1.17A 5wauA-6d14A:
undetectable
5wauC-6d14A:
undetectable
5wauc-6d14A:
undetectable		 5wauA-6d14A:
undetectable
5wauC-6d14A:
undetectable
5wauc-6d14A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6d14 TNF
RECEPTOR-ASSOCIATED
PROTEIN 1
(Danio
rerio) 		4 / 8 HIS A 525
THR A 615
HIS A 521
LEU A 598
 None
 1.11A 5xdqA-6d14A:
undetectable
5xdqC-6d14A:
undetectable
5xdqP-6d14A:
undetectable		 5xdqA-6d14A:
undetectable
5xdqC-6d14A:
undetectable
5xdqP-6d14A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6d14 TNF
RECEPTOR-ASSOCIATED
PROTEIN 1
(Danio
rerio) 		4 / 8 LEU A 598
HIS A 525
THR A 615
HIS A 521
 None
 1.11A 5xdqC-6d14A:
undetectable
5xdqN-6d14A:
undetectable
5xdqP-6d14A:
undetectable		 5xdqC-6d14A:
undetectable
5xdqN-6d14A:
undetectable
5xdqP-6d14A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6d14 TNF
RECEPTOR-ASSOCIATED
PROTEIN 1
(Danio
rerio) 		4 / 8 LEU A 598
HIS A 525
THR A 615
HIS A 521
 None
 1.10A 5xdxC-6d14A:
undetectable
5xdxN-6d14A:
undetectable
5xdxP-6d14A:
undetectable		 5xdxC-6d14A:
undetectable
5xdxN-6d14A:
undetectable
5xdxP-6d14A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6d14 TNF
RECEPTOR-ASSOCIATED
PROTEIN 1
(Danio
rerio) 		4 / 8 HIS A 525
THR A 615
HIS A 521
LEU A 598
 None
 1.12A 5z84A-6d14A:
undetectable
5z84C-6d14A:
undetectable
5z84P-6d14A:
undetectable		 5z84A-6d14A:
undetectable
5z84C-6d14A:
undetectable
5z84P-6d14A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6d14 TNF
RECEPTOR-ASSOCIATED
PROTEIN 1
(Danio
rerio) 		4 / 7 LEU A 598
HIS A 525
THR A 615
HIS A 521
 None
 1.11A 5z84C-6d14A:
undetectable
5z84N-6d14A:
undetectable
5z84P-6d14A:
undetectable		 5z84C-6d14A:
undetectable
5z84N-6d14A:
undetectable
5z84P-6d14A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6d14 TNF
RECEPTOR-ASSOCIATED
PROTEIN 1
(Danio
rerio) 		4 / 8 HIS A 525
THR A 615
HIS A 521
LEU A 598
 None
 1.13A 5z85A-6d14A:
undetectable
5z85C-6d14A:
undetectable
5z85P-6d14A:
undetectable		 5z85A-6d14A:
undetectable
5z85C-6d14A:
undetectable
5z85P-6d14A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6d14 TNF
RECEPTOR-ASSOCIATED
PROTEIN 1
(Danio
rerio) 		4 / 7 LEU A 598
HIS A 525
THR A 615
HIS A 521
 None
 1.12A 5z85C-6d14A:
undetectable
5z85N-6d14A:
0.2
5z85P-6d14A:
undetectable		 5z85C-6d14A:
undetectable
5z85N-6d14A:
undetectable
5z85P-6d14A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6d14 TNF
RECEPTOR-ASSOCIATED
PROTEIN 1
(Danio
rerio) 		4 / 8 HIS A 525
THR A 615
HIS A 521
LEU A 598
 None
 1.12A 5z86A-6d14A:
undetectable
5z86C-6d14A:
undetectable
5z86P-6d14A:
undetectable		 5z86A-6d14A:
undetectable
5z86C-6d14A:
undetectable
5z86P-6d14A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6d14 TNF
RECEPTOR-ASSOCIATED
PROTEIN 1
(Danio
rerio) 		4 / 8 LEU A 598
HIS A 525
THR A 615
HIS A 521
 None
 1.12A 5z86C-6d14A:
undetectable
5z86N-6d14A:
undetectable
5z86P-6d14A:
undetectable		 5z86C-6d14A:
undetectable
5z86N-6d14A:
undetectable
5z86P-6d14A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6d14 TNF
RECEPTOR-ASSOCIATED
PROTEIN 1
(Danio
rerio) 		4 / 8 HIS A 525
THR A 615
HIS A 521
LEU A 598
 None
 1.12A 5zcoA-6d14A:
undetectable
5zcoC-6d14A:
undetectable
5zcoP-6d14A:
undetectable		 5zcoA-6d14A:
undetectable
5zcoC-6d14A:
undetectable
5zcoP-6d14A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6d14 TNF
RECEPTOR-ASSOCIATED
PROTEIN 1
(Danio
rerio) 		4 / 8 LEU A 598
HIS A 525
THR A 615
HIS A 521
 None
 1.13A 5zcoC-6d14A:
undetectable
5zcoN-6d14A:
undetectable
5zcoP-6d14A:
undetectable		 5zcoC-6d14A:
undetectable
5zcoN-6d14A:
undetectable
5zcoP-6d14A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6d14 TNF
RECEPTOR-ASSOCIATED
PROTEIN 1
(Danio
rerio) 		4 / 8 HIS A 525
THR A 615
HIS A 521
LEU A 598
 None
 1.14A 5zcpA-6d14A:
undetectable
5zcpC-6d14A:
undetectable
5zcpP-6d14A:
undetectable		 5zcpA-6d14A:
undetectable
5zcpC-6d14A:
undetectable
5zcpP-6d14A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6d14 TNF
RECEPTOR-ASSOCIATED
PROTEIN 1
(Danio
rerio) 		4 / 8 LEU A 598
HIS A 525
THR A 615
HIS A 521
 None
 1.13A 5zcpC-6d14A:
undetectable
5zcpN-6d14A:
undetectable
5zcpP-6d14A:
undetectable		 5zcpC-6d14A:
undetectable
5zcpN-6d14A:
undetectable
5zcpP-6d14A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6d14 TNF
RECEPTOR-ASSOCIATED
PROTEIN 1
(Danio
rerio) 		4 / 8 HIS A 525
THR A 615
HIS A 521
LEU A 598
 None
 1.12A 5zcqA-6d14A:
undetectable
5zcqC-6d14A:
undetectable
5zcqP-6d14A:
undetectable		 5zcqA-6d14A:
undetectable
5zcqC-6d14A:
undetectable
5zcqP-6d14A:
undetectable