SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6d2q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M8E_B_H4BB903_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 6d2q FERM, RHOGEF
(ARHGEF) AND
PLECKSTRIN DOMAIN
PROTEIN 1
(CHONDROCYTE-DERIVED
)
(Danio
rerio) 		3 / 3 ARG A 149
ILE A 310
TRP A  95
 None
 1.12A 1m8eB-6d2qA:
undetectable		 1m8eB-6d2qA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WU8_C_ADNC502_1
(HYPOTHETICAL PROTEIN
PH0463)		 6d2q FERM, RHOGEF
(ARHGEF) AND
PLECKSTRIN DOMAIN
PROTEIN 1
(CHONDROCYTE-DERIVED
)
(Danio
rerio) 		4 / 7 PHE A 318
ASN A 263
HIS A 247
VAL A 245
 None
 1.29A 1wu8A-6d2qA:
undetectable
1wu8C-6d2qA:
undetectable		 1wu8A-6d2qA:
undetectable
1wu8C-6d2qA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E68_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 6d2q FERM, RHOGEF
(ARHGEF) AND
PLECKSTRIN DOMAIN
PROTEIN 1
(CHONDROCYTE-DERIVED
)
(Danio
rerio) 		3 / 3 ARG A 149
ILE A 310
TRP A  95
 None
 1.15A 3e68A-6d2qA:
undetectable		 3e68A-6d2qA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E6T_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 6d2q FERM, RHOGEF
(ARHGEF) AND
PLECKSTRIN DOMAIN
PROTEIN 1
(CHONDROCYTE-DERIVED
)
(Danio
rerio) 		3 / 3 ARG A 149
ILE A 310
TRP A  95
 None
 1.14A 3e6tB-6d2qA:
undetectable		 3e6tB-6d2qA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7I_B_H4BB2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 6d2q FERM, RHOGEF
(ARHGEF) AND
PLECKSTRIN DOMAIN
PROTEIN 1
(CHONDROCYTE-DERIVED
)
(Danio
rerio) 		3 / 3 ARG A 149
ILE A 310
TRP A  95
 None
 1.16A 3e7iB-6d2qA:
undetectable		 3e7iB-6d2qA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA502_0
(RNA POLYMERASE
3D-POL)		 6d2q FERM, RHOGEF
(ARHGEF) AND
PLECKSTRIN DOMAIN
PROTEIN 1
(CHONDROCYTE-DERIVED
)
(Danio
rerio) 		3 / 3 ARG A 268
LYS A 269
LYS A 280
 None
 1.29A 4k50A-6d2qA:
undetectable		 4k50A-6d2qA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_E_ACTE502_0
(RNA POLYMERASE
3D-POL)		 6d2q FERM, RHOGEF
(ARHGEF) AND
PLECKSTRIN DOMAIN
PROTEIN 1
(CHONDROCYTE-DERIVED
)
(Danio
rerio) 		3 / 3 ARG A 268
LYS A 269
LYS A 280
 None
 1.29A 4k50E-6d2qA:
undetectable		 4k50E-6d2qA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_I_ACTI506_0
(RNA POLYMERASE
3D-POL)		 6d2q FERM, RHOGEF
(ARHGEF) AND
PLECKSTRIN DOMAIN
PROTEIN 1
(CHONDROCYTE-DERIVED
)
(Danio
rerio) 		3 / 3 ARG A 268
LYS A 269
LYS A 280
 None
 1.28A 4k50I-6d2qA:
undetectable		 4k50I-6d2qA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_A_ERMA2001_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 6d2q FERM, RHOGEF
(ARHGEF) AND
PLECKSTRIN DOMAIN
PROTEIN 1
(CHONDROCYTE-DERIVED
)
(Danio
rerio) 		5 / 12 LEU A  76
MET A  47
PHE A  55
LEU A 114
LEU A  66
 None
 1.14A 5tudA-6d2qA:
undetectable		 5tudA-6d2qA:
undetectable