SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6d2v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 6d2v TERB OXIDOREDUCTASE
(Streptomyces) 		5 / 10 ARG A 277
THR A 282
GLY A 237
HIS A 219
ALA A 170
 None
 1.31A 1c9sB-6d2vA:
undetectable
1c9sC-6d2vA:
undetectable		 1c9sB-6d2vA:
undetectable
1c9sC-6d2vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 6d2v TERB OXIDOREDUCTASE
(Streptomyces) 		5 / 10 ARG A 277
THR A 282
GLY A 237
HIS A 219
ALA A 170
 None
 1.30A 1c9sG-6d2vA:
undetectable
1c9sH-6d2vA:
undetectable		 1c9sG-6d2vA:
undetectable
1c9sH-6d2vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_A_ACTA3001_0
(BETA-CARBONIC
ANHYDRASE)		 6d2v TERB OXIDOREDUCTASE
(Streptomyces) 		4 / 8 ASP A 215
HIS A 219
GLY A 238
GLY A 237
 None
 0.83A 1ekjA-6d2vA:
undetectable
1ekjB-6d2vA:
undetectable		 1ekjA-6d2vA:
undetectable
1ekjB-6d2vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_E_ACTE3005_0
(BETA-CARBONIC
ANHYDRASE)		 6d2v TERB OXIDOREDUCTASE
(Streptomyces) 		4 / 7 ASP A 215
HIS A 219
GLY A 238
GLY A 237
 None
 0.88A 1ekjE-6d2vA:
undetectable
1ekjF-6d2vA:
undetectable		 1ekjE-6d2vA:
undetectable
1ekjF-6d2vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_G_ACTG3002_0
(BETA-CARBONIC
ANHYDRASE)		 6d2v TERB OXIDOREDUCTASE
(Streptomyces) 		4 / 8 ASP A 215
HIS A 219
GLY A 238
GLY A 237
 None
 0.86A 1ekjG-6d2vA:
undetectable
1ekjH-6d2vA:
undetectable		 1ekjG-6d2vA:
undetectable
1ekjH-6d2vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 6d2v TERB OXIDOREDUCTASE
(Streptomyces) 		5 / 10 ARG A 277
THR A 282
GLY A 237
HIS A 219
ALA A 170
 None
 1.31A 1gtfC-6d2vA:
undetectable
1gtfD-6d2vA:
undetectable		 1gtfC-6d2vA:
undetectable
1gtfD-6d2vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 6d2v TERB OXIDOREDUCTASE
(Streptomyces) 		5 / 10 ARG A 277
THR A 282
GLY A 237
HIS A 219
ALA A 170
 None
 1.30A 1gtfG-6d2vA:
undetectable
1gtfH-6d2vA:
undetectable		 1gtfG-6d2vA:
undetectable
1gtfH-6d2vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 6d2v TERB OXIDOREDUCTASE
(Streptomyces) 		5 / 10 ARG A 277
THR A 282
GLY A 237
HIS A 219
ALA A 170
 None
 1.33A 1gtfH-6d2vA:
undetectable
1gtfI-6d2vA:
undetectable		 1gtfH-6d2vA:
undetectable
1gtfI-6d2vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 6d2v TERB OXIDOREDUCTASE
(Streptomyces) 		5 / 11 GLY A 237
HIS A 219
ALA A 170
ARG A 277
THR A 282
 None
 1.30A 1gtfU-6d2vA:
undetectable
1gtfV-6d2vA:
undetectable		 1gtfU-6d2vA:
undetectable
1gtfV-6d2vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_M_TRPM81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6d2v TERB OXIDOREDUCTASE
(Streptomyces) 		5 / 11 GLY A 237
HIS A 219
ALA A 170
ARG A 277
THR A 282
 None
 1.32A 1utdM-6d2vA:
undetectable
1utdN-6d2vA:
undetectable		 1utdM-6d2vA:
undetectable
1utdN-6d2vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1100_1
(SERUM ALBUMIN)		 6d2v TERB OXIDOREDUCTASE
(Streptomyces) 		4 / 6 HIS A  76
PHE A 111
TYR A  64
GLY A  99
 None
 1.32A 2i30A-6d2vA:
undetectable		 2i30A-6d2vA:
8.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_A_SAMA400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 6d2v TERB OXIDOREDUCTASE
(Streptomyces) 		3 / 3 ASN A 235
ARG A 171
ASP A 136
 None
 0.80A 2qe6A-6d2vA:
4.9		 2qe6A-6d2vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_B_SAMB400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 6d2v TERB OXIDOREDUCTASE
(Streptomyces) 		3 / 3 ASN A 235
ARG A 171
ASP A 136
 None
 0.84A 2qe6B-6d2vA:
4.9		 2qe6B-6d2vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIA_B_SAMB206_0
(UPF0217 PROTEIN
MJ1640)		 6d2v TERB OXIDOREDUCTASE
(Streptomyces) 		4 / 5 SER A 115
GLY A 148
GLU A 153
CYH A  98
 None
 1.16A 3aiaA-6d2vA:
undetectable
3aiaB-6d2vA:
undetectable		 3aiaA-6d2vA:
undetectable
3aiaB-6d2vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CAS_A_ASDA332_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 6d2v TERB OXIDOREDUCTASE
(Streptomyces) 		5 / 10 TRP A 236
ASN A  27
VAL A  29
VAL A   8
LEU A  75
 None
 1.46A 3casA-6d2vA:
undetectable		 3casA-6d2vA:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_G_PZIG801_0
(GLUTAMATE RECEPTOR 2)		 6d2v TERB OXIDOREDUCTASE
(Streptomyces) 		3 / 3 PRO A 199
SER A 264
ASN A 206
 None
 0.75A 3lslG-6d2vA:
undetectable		 3lslG-6d2vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7V_A_SAMA992_0
(METHYLORNITHINE
SYNTHASE PYLB)		 6d2v TERB OXIDOREDUCTASE
(Streptomyces) 		5 / 12 GLY A  10
GLY A  13
LEU A 211
VAL A 114
ALA A 170
 NDP  A 401 (-3.0A)
NDP  A 401 (-3.0A)
None
NDP  A 401 (-3.9A)
None
 1.12A 3t7vA-6d2vA:
undetectable		 3t7vA-6d2vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA301_1
(CHITOSANASE)		 6d2v TERB OXIDOREDUCTASE
(Streptomyces) 		4 / 4 ASP A 214
GLY A 177
PRO A 178
GLN A  14
 None
None
None
NDP  A 401 (-4.9A)
 1.45A 4oltA-6d2vA:
undetectable		 4oltA-6d2vA:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_2
(ADENOSINE KINASE)		 6d2v TERB OXIDOREDUCTASE
(Streptomyces) 		4 / 4 ALA A  97
VAL A  79
GLY A  10
THR A   9
 None
NDP  A 401 (-3.7A)
NDP  A 401 (-3.0A)
None
 1.08A 4ubeA-6d2vA:
undetectable		 4ubeA-6d2vA:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6d2v TERB OXIDOREDUCTASE
(Streptomyces) 		5 / 10 ARG A 277
THR A 282
GLY A 237
HIS A 219
ALA A 170
 None
 1.32A 5eeuD-6d2vA:
undetectable
5eeuE-6d2vA:
undetectable		 5eeuD-6d2vA:
undetectable
5eeuE-6d2vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6d2v TERB OXIDOREDUCTASE
(Streptomyces) 		5 / 10 ARG A 277
THR A 282
GLY A 237
HIS A 219
ALA A 170
 None
 1.33A 5eeuH-6d2vA:
undetectable
5eeuI-6d2vA:
undetectable		 5eeuH-6d2vA:
undetectable
5eeuI-6d2vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6d2v TERB OXIDOREDUCTASE
(Streptomyces) 		5 / 10 ARG A 277
THR A 282
GLY A 237
HIS A 219
ALA A 170
 None
 1.32A 5eeuJ-6d2vA:
undetectable
5eeuK-6d2vA:
undetectable		 5eeuJ-6d2vA:
undetectable
5eeuK-6d2vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6d2v TERB OXIDOREDUCTASE
(Streptomyces) 		5 / 10 ARG A 277
THR A 282
GLY A 237
HIS A 219
ALA A 170
 None
 1.32A 5eevD-6d2vA:
undetectable
5eevE-6d2vA:
undetectable		 5eevD-6d2vA:
undetectable
5eevE-6d2vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6d2v TERB OXIDOREDUCTASE
(Streptomyces) 		5 / 10 ARG A 277
THR A 282
GLY A 237
HIS A 219
ALA A 170
 None
 1.32A 5eevJ-6d2vA:
undetectable
5eevK-6d2vA:
undetectable		 5eevJ-6d2vA:
undetectable
5eevK-6d2vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6d2v TERB OXIDOREDUCTASE
(Streptomyces) 		5 / 10 ARG A 277
THR A 282
GLY A 237
HIS A 219
ALA A 170
 None
 1.33A 5eewD-6d2vA:
undetectable
5eewE-6d2vA:
undetectable		 5eewD-6d2vA:
undetectable
5eewE-6d2vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6d2v TERB OXIDOREDUCTASE
(Streptomyces) 		5 / 10 ARG A 277
THR A 282
GLY A 237
HIS A 219
ALA A 170
 None
 1.33A 5eewH-6d2vA:
undetectable
5eewI-6d2vA:
undetectable		 5eewH-6d2vA:
undetectable
5eewI-6d2vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6d2v TERB OXIDOREDUCTASE
(Streptomyces) 		5 / 10 ARG A 277
THR A 282
GLY A 237
HIS A 219
ALA A 170
 None
 1.32A 5eewJ-6d2vA:
undetectable
5eewK-6d2vA:
undetectable		 5eewJ-6d2vA:
undetectable
5eewK-6d2vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6d2v TERB OXIDOREDUCTASE
(Streptomyces) 		5 / 10 ARG A 277
THR A 282
GLY A 237
HIS A 219
ALA A 170
 None
 1.33A 5eexD-6d2vA:
undetectable
5eexE-6d2vA:
undetectable		 5eexD-6d2vA:
undetectable
5eexE-6d2vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6d2v TERB OXIDOREDUCTASE
(Streptomyces) 		5 / 10 ARG A 277
THR A 282
GLY A 237
HIS A 219
ALA A 170
 None
 1.33A 5eexH-6d2vA:
undetectable
5eexI-6d2vA:
undetectable		 5eexH-6d2vA:
undetectable
5eexI-6d2vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6d2v TERB OXIDOREDUCTASE
(Streptomyces) 		5 / 11 ARG A 277
THR A 282
GLY A 237
HIS A 219
ALA A 170
 None
 1.31A 5eexI-6d2vA:
undetectable
5eexJ-6d2vA:
undetectable		 5eexI-6d2vA:
undetectable
5eexJ-6d2vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6d2v TERB OXIDOREDUCTASE
(Streptomyces) 		5 / 10 ARG A 277
THR A 282
GLY A 237
HIS A 219
ALA A 170
 None
 1.32A 5eexJ-6d2vA:
undetectable
5eexK-6d2vA:
undetectable		 5eexJ-6d2vA:
undetectable
5eexK-6d2vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6d2v TERB OXIDOREDUCTASE
(Streptomyces) 		5 / 10 ARG A 277
THR A 282
GLY A 237
HIS A 219
ALA A 170
 None
 1.33A 5eeyD-6d2vA:
undetectable
5eeyE-6d2vA:
undetectable		 5eeyD-6d2vA:
undetectable
5eeyE-6d2vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6d2v TERB OXIDOREDUCTASE
(Streptomyces) 		5 / 11 ARG A 277
THR A 282
GLY A 237
HIS A 219
ALA A 170
 None
 1.31A 5eeyI-6d2vA:
undetectable
5eeyJ-6d2vA:
undetectable		 5eeyI-6d2vA:
undetectable
5eeyJ-6d2vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6d2v TERB OXIDOREDUCTASE
(Streptomyces) 		5 / 10 ARG A 277
THR A 282
GLY A 237
HIS A 219
ALA A 170
 None
 1.32A 5eeyJ-6d2vA:
undetectable
5eeyK-6d2vA:
undetectable		 5eeyJ-6d2vA:
undetectable
5eeyK-6d2vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6d2v TERB OXIDOREDUCTASE
(Streptomyces) 		5 / 10 ARG A 277
THR A 282
GLY A 237
HIS A 219
ALA A 170
 None
 1.33A 5eezD-6d2vA:
undetectable
5eezE-6d2vA:
undetectable		 5eezD-6d2vA:
undetectable
5eezE-6d2vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6d2v TERB OXIDOREDUCTASE
(Streptomyces) 		5 / 11 ARG A 277
THR A 282
GLY A 237
HIS A 219
ALA A 170
 None
 1.31A 5eezI-6d2vA:
undetectable
5eezJ-6d2vA:
undetectable		 5eezI-6d2vA:
undetectable
5eezJ-6d2vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6d2v TERB OXIDOREDUCTASE
(Streptomyces) 		5 / 10 ARG A 277
THR A 282
GLY A 237
HIS A 219
ALA A 170
 None
 1.33A 5ef0D-6d2vA:
undetectable
5ef0E-6d2vA:
undetectable		 5ef0D-6d2vA:
undetectable
5ef0E-6d2vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6d2v TERB OXIDOREDUCTASE
(Streptomyces) 		5 / 11 ARG A 277
THR A 282
GLY A 237
HIS A 219
ALA A 170
 None
 1.31A 5ef0I-6d2vA:
undetectable
5ef0J-6d2vA:
undetectable		 5ef0I-6d2vA:
undetectable
5ef0J-6d2vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6d2v TERB OXIDOREDUCTASE
(Streptomyces) 		5 / 10 ARG A 277
THR A 282
GLY A 237
HIS A 219
ALA A 170
 None
 1.33A 5ef1D-6d2vA:
undetectable
5ef1E-6d2vA:
undetectable		 5ef1D-6d2vA:
undetectable
5ef1E-6d2vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6d2v TERB OXIDOREDUCTASE
(Streptomyces) 		5 / 11 ARG A 277
THR A 282
GLY A 237
HIS A 219
ALA A 170
 None
 1.31A 5ef1I-6d2vA:
undetectable
5ef1J-6d2vA:
undetectable		 5ef1I-6d2vA:
undetectable
5ef1J-6d2vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6d2v TERB OXIDOREDUCTASE
(Streptomyces) 		5 / 10 ARG A 277
THR A 282
GLY A 237
HIS A 219
ALA A 170
 None
 1.33A 5ef2D-6d2vA:
undetectable
5ef2E-6d2vA:
undetectable		 5ef2D-6d2vA:
undetectable
5ef2E-6d2vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6d2v TERB OXIDOREDUCTASE
(Streptomyces) 		5 / 11 ARG A 277
THR A 282
GLY A 237
HIS A 219
ALA A 170
 None
 1.31A 5ef2I-6d2vA:
undetectable
5ef2J-6d2vA:
undetectable		 5ef2I-6d2vA:
undetectable
5ef2J-6d2vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6d2v TERB OXIDOREDUCTASE
(Streptomyces) 		5 / 10 ARG A 277
THR A 282
GLY A 237
HIS A 219
ALA A 170
 None
 1.33A 5ef3D-6d2vA:
undetectable
5ef3E-6d2vA:
undetectable		 5ef3D-6d2vA:
undetectable
5ef3E-6d2vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6d2v TERB OXIDOREDUCTASE
(Streptomyces) 		5 / 11 ARG A 277
THR A 282
GLY A 237
HIS A 219
ALA A 170
 None
 1.32A 5ef3I-6d2vA:
undetectable
5ef3J-6d2vA:
undetectable		 5ef3I-6d2vA:
undetectable
5ef3J-6d2vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 6d2v TERB OXIDOREDUCTASE
(Streptomyces) 		3 / 3 TYR A  64
ARG A 100
THR A 103
 None
None
SCN  A 402 ( 4.1A)
 1.03A 5z84J-6d2vA:
undetectable		 5z84J-6d2vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BPL_B_PA1B605_1
(LIPID A EXPORT
ATP-BINDING/PERMEASE
PROTEIN MSBA)		 6d2v TERB OXIDOREDUCTASE
(Streptomyces) 		3 / 3 ARG A 157
ARG A 277
ARG A 171
 None
 0.99A 6bplA-6d2vA:
undetectable
6bplB-6d2vA:
undetectable		 6bplA-6d2vA:
19.54
6bplB-6d2vA:
19.54