SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6d3u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC685_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 6d3u ULVAN LYASE
(Nonlabens
ulvanivorans) 		4 / 8 ALA A 254
ASP A 199
ILE A 200
ILE A 142
 None
 0.83A 1p7lD-6d3uA:
undetectable		 1p7lD-6d3uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC885_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 6d3u ULVAN LYASE
(Nonlabens
ulvanivorans) 		4 / 8 ALA A 254
ASP A 199
ILE A 200
ILE A 142
 None
 0.83A 1p7lC-6d3uA:
undetectable		 1p7lC-6d3uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P91_B_SAMB2401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE A)		 6d3u ULVAN LYASE
(Nonlabens
ulvanivorans) 		5 / 12 TYR A 281
GLY A 285
GLY A 146
ILE A 101
THR A 113
 83Y  A 404 ( 4.0A)
None
None
None
None
 1.02A 1p91B-6d3uA:
undetectable		 1p91B-6d3uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_A_SAMA385_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 6d3u ULVAN LYASE
(Nonlabens
ulvanivorans) 		4 / 8 ALA A 254
ASP A 199
ILE A 200
ILE A 142
 None
 0.83A 1rg9B-6d3uA:
undetectable		 1rg9B-6d3uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_B_SAMB485_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 6d3u ULVAN LYASE
(Nonlabens
ulvanivorans) 		4 / 8 ALA A 254
ASP A 199
ILE A 200
ILE A 142
 None
 0.84A 1rg9A-6d3uA:
undetectable		 1rg9A-6d3uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC585_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 6d3u ULVAN LYASE
(Nonlabens
ulvanivorans) 		4 / 8 ALA A 254
ASP A 199
ILE A 200
ILE A 142
 None
 0.83A 1rg9D-6d3uA:
undetectable		 1rg9D-6d3uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC685_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 6d3u ULVAN LYASE
(Nonlabens
ulvanivorans) 		4 / 8 ALA A 254
ASP A 199
ILE A 200
ILE A 142
 None
 0.82A 1rg9C-6d3uA:
undetectable		 1rg9C-6d3uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UOB_A_PNNA1311_1
(DEACETOXYCEPHALOSPOR
IN C SYNTHETASE)		 6d3u ULVAN LYASE
(Nonlabens
ulvanivorans) 		3 / 3 ARG A 135
ARG A 137
ILE A  74
 None
 0.80A 1uobA-6d3uA:
undetectable		 1uobA-6d3uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 6d3u ULVAN LYASE
(Nonlabens
ulvanivorans) 		4 / 7 TYR A 278
TYR A  99
GLY A  75
TYR A  86
 None
 0.74A 2g70A-6d3uA:
undetectable		 2g70A-6d3uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 6d3u ULVAN LYASE
(Nonlabens
ulvanivorans) 		4 / 7 TYR A 278
TYR A  99
GLY A  75
TYR A  86
 None
 0.78A 2g70B-6d3uA:
undetectable		 2g70B-6d3uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 6d3u ULVAN LYASE
(Nonlabens
ulvanivorans) 		4 / 6 TYR A 278
TYR A  99
GLY A  75
TYR A  86
 None
 0.73A 2g72A-6d3uA:
undetectable		 2g72A-6d3uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_B_SAMB2002_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 6d3u ULVAN LYASE
(Nonlabens
ulvanivorans) 		4 / 7 TYR A 278
TYR A  99
GLY A  75
TYR A  86
 None
 0.77A 2g72B-6d3uA:
undetectable		 2g72B-6d3uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA801_1
(TRANSPORTER)		 6d3u ULVAN LYASE
(Nonlabens
ulvanivorans) 		5 / 11 LEU A 140
ARG A 141
GLN A 229
ALA A 293
ASP A  46
 None
 1.21A 2q72A-6d3uA:
undetectable		 2q72A-6d3uA:
8.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_A_KLNA1501_1
(CYTOCHROME P450 3A4)		 6d3u ULVAN LYASE
(Nonlabens
ulvanivorans) 		5 / 10 PHE A 136
SER A  89
ILE A  98
ILE A  91
GLY A 138
 None
 1.33A 2v0mA-6d3uA:
undetectable		 2v0mA-6d3uA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VE3_B_REAB1445_1
(PUTATIVE CYTOCHROME
P450 120)		 6d3u ULVAN LYASE
(Nonlabens
ulvanivorans) 		5 / 12 PHE A 198
ALA A  84
VAL A 283
GLY A 146
GLN A 195
 None
 1.15A 2ve3B-6d3uA:
undetectable		 2ve3B-6d3uA:
10.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CKZ_A_ZMRA469_2
(NEURAMINIDASE)		 6d3u ULVAN LYASE
(Nonlabens
ulvanivorans) 		4 / 6 ASP A 253
TRP A 263
ILE A 265
SER A 274
 None
 1.39A 3ckzA-6d3uA:
undetectable		 3ckzA-6d3uA:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_A_SAMA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 6d3u ULVAN LYASE
(Nonlabens
ulvanivorans) 		4 / 8 ALA A 254
ASP A 199
ILE A 200
ILE A 142
 None
 0.85A 4ndnB-6d3uA:
undetectable		 4ndnB-6d3uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJG_A_SAMA302_0
(7-CARBOXY-7-DEAZAGUA
NINE SYNTHASE)		 6d3u ULVAN LYASE
(Nonlabens
ulvanivorans) 		5 / 12 THR A  49
GLU A  47
LYS A 226
VAL A 196
ASP A 187
 None
 1.43A 4njgA-6d3uA:
undetectable		 4njgA-6d3uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJH_A_SAMA302_0
(7-CARBOXY-7-DEAZAGUA
NINE SYNTHASE)		 6d3u ULVAN LYASE
(Nonlabens
ulvanivorans) 		5 / 12 THR A  49
GLU A  47
LYS A 226
VAL A 196
ASP A 187
 None
 1.39A 4njhA-6d3uA:
undetectable		 4njhA-6d3uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJH_B_SAMB302_0
(7-CARBOXY-7-DEAZAGUA
NINE SYNTHASE)		 6d3u ULVAN LYASE
(Nonlabens
ulvanivorans) 		5 / 12 THR A  49
GLU A  47
LYS A 226
VAL A 196
ASP A 187
 None
 1.41A 4njhB-6d3uA:
undetectable		 4njhB-6d3uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJI_A_SAMA302_0
(7-CARBOXY-7-DEAZAGUA
NINE SYNTHASE)		 6d3u ULVAN LYASE
(Nonlabens
ulvanivorans) 		5 / 12 THR A  49
GLU A  47
LYS A 226
VAL A 196
ASP A 187
 None
 1.41A 4njiA-6d3uA:
undetectable		 4njiA-6d3uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJI_B_SAMB302_0
(7-CARBOXY-7-DEAZAGUA
NINE SYNTHASE)		 6d3u ULVAN LYASE
(Nonlabens
ulvanivorans) 		5 / 12 THR A  49
GLU A  47
LYS A 226
VAL A 196
ASP A 187
 None
 1.39A 4njiB-6d3uA:
undetectable		 4njiB-6d3uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJJ_A_SAMA302_0
(7-CARBOXY-7-DEAZAGUA
NINE SYNTHASE)		 6d3u ULVAN LYASE
(Nonlabens
ulvanivorans) 		5 / 12 THR A  49
GLU A  47
LYS A 226
VAL A 196
ASP A 187
 None
 1.38A 4njjA-6d3uA:
undetectable		 4njjA-6d3uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJJ_B_SAMB302_0
(7-CARBOXY-7-DEAZAGUA
NINE SYNTHASE)		 6d3u ULVAN LYASE
(Nonlabens
ulvanivorans) 		5 / 12 THR A  49
GLU A  47
LYS A 226
VAL A 196
ASP A 187
 None
 1.38A 4njjB-6d3uA:
undetectable		 4njjB-6d3uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJK_A_SAMA302_0
(7-CARBOXY-7-DEAZAGUA
NINE SYNTHASE)		 6d3u ULVAN LYASE
(Nonlabens
ulvanivorans) 		5 / 12 THR A  49
GLU A  47
LYS A 226
VAL A 196
ASP A 187
 None
 1.43A 4njkA-6d3uA:
undetectable		 4njkA-6d3uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJK_B_SAMB302_0
(7-CARBOXY-7-DEAZAGUA
NINE SYNTHASE)		 6d3u ULVAN LYASE
(Nonlabens
ulvanivorans) 		5 / 12 THR A  49
GLU A  47
LYS A 226
VAL A 196
ASP A 187
 None
 1.44A 4njkB-6d3uA:
undetectable		 4njkB-6d3uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 6d3u ULVAN LYASE
(Nonlabens
ulvanivorans) 		5 / 12 GLN A 126
ALA A 130
GLY A 129
THR A 128
THR A 248
 None
 1.18A 5l5fH-6d3uA:
undetectable
5l5fI-6d3uA:
undetectable		 5l5fH-6d3uA:
16.09
5l5fI-6d3uA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 6d3u ULVAN LYASE
(Nonlabens
ulvanivorans) 		5 / 12 GLN A 126
ALA A 130
GLY A 129
THR A 128
THR A 248
 None
 1.18A 5l5fV-6d3uA:
undetectable
5l5fW-6d3uA:
undetectable		 5l5fV-6d3uA:
16.09
5l5fW-6d3uA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUN_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 6d3u ULVAN LYASE
(Nonlabens
ulvanivorans) 		5 / 9 ALA A 252
ILE A 200
ILE A 256
ILE A 232
ALA A 161
 None
 0.95A 5nunA-6d3uA:
undetectable		 5nunA-6d3uA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8S_B_SAMB402_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 6d3u ULVAN LYASE
(Nonlabens
ulvanivorans) 		4 / 8 ALA A 254
ASP A 199
ILE A 200
ILE A 142
 None
 0.86A 5t8sA-6d3uA:
undetectable		 5t8sA-6d3uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 6d3u ULVAN LYASE
(Nonlabens
ulvanivorans) 		5 / 10 TYR A 278
ILE A 232
ILE A 256
LEU A 221
ILE A 276
 None
 1.42A 5vkqA-6d3uA:
undetectable
5vkqD-6d3uA:
undetectable		 5vkqA-6d3uA:
undetectable
5vkqD-6d3uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1808_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 6d3u ULVAN LYASE
(Nonlabens
ulvanivorans) 		5 / 10 ILE A 276
TYR A 278
ILE A 232
ILE A 256
LEU A 221
 None
 1.43A 5vkqA-6d3uA:
undetectable
5vkqB-6d3uA:
undetectable		 5vkqA-6d3uA:
undetectable
5vkqB-6d3uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 6d3u ULVAN LYASE
(Nonlabens
ulvanivorans) 		5 / 10 ILE A 276
TYR A 278
ILE A 232
ILE A 256
LEU A 221
 None
 1.43A 5vkqC-6d3uA:
undetectable
5vkqD-6d3uA:
undetectable		 5vkqC-6d3uA:
undetectable
5vkqD-6d3uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_A_SAMA401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 6d3u ULVAN LYASE
(Nonlabens
ulvanivorans) 		3 / 3 ASP A 109
ARG A  64
ASP A 173
 None
None
PO4  A 403 ( 4.1A)
 0.86A 5zvgA-6d3uA:
undetectable		 5zvgA-6d3uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_B_SAMB401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 6d3u ULVAN LYASE
(Nonlabens
ulvanivorans) 		3 / 3 ASP A 109
ARG A  64
ASP A 173
 None
None
PO4  A 403 ( 4.1A)
 0.84A 5zvgB-6d3uA:
undetectable		 5zvgB-6d3uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBN_B_SAMB401_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 6d3u ULVAN LYASE
(Nonlabens
ulvanivorans) 		4 / 7 ALA A 254
ASP A 199
ILE A 200
ILE A 142
 None
 0.89A 6fbnA-6d3uA:
undetectable		 6fbnA-6d3uA:
undetectable