SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6d6u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_B_CHDB1250_0
(ALCOHOL
DEHYDROGENASE)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
GAMMA-2,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT GAMMA-2
(Homo
sapiens) 		3 / 3 MET E 276
LEU E 279
SER E 280
 None
 0.36A 1ee2A-6d6uE:
undetectable		 1ee2A-6d6uE:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I7Z_A_COCA301_2
(CHIMERA OF IG KAPPA
CHAIN: HUMAN
CONSTANT REGION AND
MOUSE VARIABLE
REGION
CHIMERA OF IG
GAMMA-1 CHAIN: HUMAN
CONSTANT REGION AND
MOUSE VARIABLE
REGION)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
(Homo
sapiens) 		4 / 5 TYR B 340
TYR B 344
PRO B 147
ASP B 145
 None
 1.48A 1i7zB-6d6uB:
2.1		 1i7zB-6d6uB:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_E_THAE5_1
(LIVER
CARBOXYLESTERASE I)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
BETA-2,GAMMA-AMINOBU
TYRIC ACID RECEPTOR
SUBUNIT BETA-2
(Homo
sapiens) 		5 / 12 VAL A  12
VAL A  87
LEU A  81
LEU A  83
LEU A  91
 None
 1.07A 1mx1E-6d6uA:
undetectable		 1mx1E-6d6uA:
11.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RA2_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
GAMMA-2,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT GAMMA-2
(Homo
sapiens) 		5 / 12 ILE E  62
LEU E 206
PHE E 227
ILE E  74
THR E 193
 None
 0.98A 1ra2A-6d6uE:
undetectable		 1ra2A-6d6uE:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RB2_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
GAMMA-2,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT GAMMA-2
(Homo
sapiens) 		5 / 12 ILE E  62
LEU E 206
PHE E 227
ILE E  74
THR E 193
 None
 0.98A 1rb2A-6d6uE:
undetectable		 1rb2A-6d6uE:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RB2_B_FOLB161_0
(DIHYDROFOLATE
REDUCTASE)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
GAMMA-2,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT GAMMA-2
(Homo
sapiens) 		5 / 12 ILE E  62
LEU E 206
PHE E 227
ILE E  74
THR E 193
 None
 0.99A 1rb2B-6d6uE:
undetectable		 1rb2B-6d6uE:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RE7_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
GAMMA-2,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT GAMMA-2
(Homo
sapiens) 		5 / 12 ILE E  62
LEU E 206
PHE E 227
ILE E  74
THR E 193
 None
 1.00A 1re7A-6d6uE:
undetectable		 1re7A-6d6uE:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RX2_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
GAMMA-2,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT GAMMA-2
(Homo
sapiens) 		5 / 12 ILE E  62
LEU E 206
PHE E 227
ILE E  74
THR E 193
 None
 0.98A 1rx2A-6d6uE:
undetectable		 1rx2A-6d6uE:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RX7_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
GAMMA-2,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT GAMMA-2
(Homo
sapiens) 		5 / 12 ILE E  62
LEU E 206
PHE E 227
ILE E  74
THR E 193
 None
 0.98A 1rx7A-6d6uE:
undetectable		 1rx7A-6d6uE:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CC8_A_RBFA1067_1
(VNG1446H)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
GAMMA-2,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT GAMMA-2
(Homo
sapiens) 		3 / 3 PHE E 203
VAL E 190
TRP E 196
 None
 0.84A 2cc8A-6d6uE:
1.3		 2cc8A-6d6uE:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CCB_A_RBFA1067_1
(VNG1446H)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
GAMMA-2,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT GAMMA-2
(Homo
sapiens) 		3 / 3 PHE E 203
VAL E 190
TRP E 196
 None
 0.83A 2ccbA-6d6uE:
1.3		 2ccbA-6d6uE:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D0K_B_FOLB2161_0
(DIHYDROFOLATE
REDUCTASE)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
GAMMA-2,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT GAMMA-2
(Homo
sapiens) 		5 / 12 ILE E  62
LEU E 206
PHE E 227
ILE E  74
THR E 193
 None
 0.99A 2d0kB-6d6uE:
undetectable		 2d0kB-6d6uE:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_D_SALD5006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
BETA-2,GAMMA-AMINOBU
TYRIC ACID RECEPTOR
SUBUNIT BETA-2
(Homo
sapiens) 		4 / 5 ARG A 129
THR A 131
LEU A  59
ALA A  45
 None
 1.42A 2e1qD-6d6uA:
2.4		 2e1qD-6d6uA:
5.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VX9_A_RBFA1064_1
(DODECIN)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
GAMMA-2,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT GAMMA-2
(Homo
sapiens) 		3 / 3 PHE E 203
VAL E 190
TRP E 196
 None
 0.84A 2vx9A-6d6uE:
1.3		 2vx9A-6d6uE:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_2
(BETA-1 ADRENERGIC
RECEPTOR)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
(Homo
sapiens) 		3 / 3 VAL B 238
ASN B 337
TRP B 341
 None
 0.98A 2y00B-6d6uB:
4.4		 2y00B-6d6uB:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_2
(BETA-1 ADRENERGIC
RECEPTOR)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
GAMMA-2,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT GAMMA-2
(Homo
sapiens) 		3 / 3 VAL E 248
ASN E 347
TRP E 351
 None
 0.83A 2y00B-6d6uE:
3.4		 2y00B-6d6uE:
12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
(Homo
sapiens) 		5 / 12 PHE B 101
VAL B 198
VAL B 135
LEU B 133
ILE B  62
 None
 0.69A 3elzA-6d6uB:
undetectable		 3elzA-6d6uB:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I45_A_NIOA500_1
(TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
BETA-2,GAMMA-AMINOBU
TYRIC ACID RECEPTOR
SUBUNIT BETA-2
(Homo
sapiens) 		4 / 8 LEU B 118
TYR A  97
TYR A 157
PHE B  65
 None
None
ABU  A 405 (-4.4A)
ABU  A 405 (-4.6A)
 0.99A 3i45A-6d6uB:
undetectable		 3i45A-6d6uB:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_A_MTXA164_2
(DIHYDROFOLATE
REDUCTASE)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
GAMMA-2,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT GAMMA-2
(Homo
sapiens) 		4 / 4 ILE E  62
PHE E 227
ILE E  74
THR E 193
 None
 1.13A 3ia4A-6d6uE:
undetectable		 3ia4A-6d6uE:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_A_TFPA202_1
(PROTEIN S100-A4)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
BETA-2,GAMMA-AMINOBU
TYRIC ACID RECEPTOR
SUBUNIT BETA-2
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
GAMMA-2,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT GAMMA-2
(Homo
sapiens) 		5 / 12 LEU E 167
PHE E 113
ILE E 147
ASP A  48
SER A  46
 None
 1.20A 3ko0A-6d6uE:
undetectable
3ko0B-6d6uE:
undetectable
3ko0C-6d6uE:
undetectable
3ko0D-6d6uE:
undetectable		 3ko0A-6d6uE:
21.15
3ko0B-6d6uE:
21.15
3ko0C-6d6uE:
21.15
3ko0D-6d6uE:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_C_TFPC202_1
(PROTEIN S100-A4)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
(Homo
sapiens) 		5 / 11 PHE B 296
SER B 241
LEU B 331
ILE B 335
PHE B 289
 None
 1.33A 3ko0A-6d6uB:
1.8
3ko0B-6d6uB:
undetectable
3ko0C-6d6uB:
1.8
3ko0D-6d6uB:
1.9		 3ko0A-6d6uB:
20.39
3ko0B-6d6uB:
20.39
3ko0C-6d6uB:
20.39
3ko0D-6d6uB:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_D_TFPD202_1
(PROTEIN S100-A4)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
(Homo
sapiens) 		5 / 11 LEU B 331
ILE B 335
PHE B 289
PHE B 296
SER B 241
 None
 1.32A 3ko0C-6d6uB:
1.7
3ko0D-6d6uB:
1.9
3ko0E-6d6uB:
1.1
3ko0F-6d6uB:
1.8		 3ko0C-6d6uB:
20.39
3ko0D-6d6uB:
20.39
3ko0E-6d6uB:
20.39
3ko0F-6d6uB:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_D_TFPD202_1
(PROTEIN S100-A4)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
BETA-2,GAMMA-AMINOBU
TYRIC ACID RECEPTOR
SUBUNIT BETA-2
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
GAMMA-2,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT GAMMA-2
(Homo
sapiens) 		5 / 11 LEU E 167
PHE E 113
ILE E 147
ASP A  48
SER A  46
 None
 1.20A 3ko0C-6d6uE:
undetectable
3ko0D-6d6uE:
undetectable
3ko0E-6d6uE:
undetectable
3ko0F-6d6uE:
undetectable		 3ko0C-6d6uE:
21.15
3ko0D-6d6uE:
21.15
3ko0E-6d6uE:
21.15
3ko0F-6d6uE:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_E_TFPE202_1
(PROTEIN S100-A4)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
(Homo
sapiens) 		5 / 11 SER B 241
PHE B 296
LEU B 331
ILE B 335
PHE B 289
 None
 1.34A 3ko0C-6d6uB:
1.8
3ko0D-6d6uB:
1.9
3ko0E-6d6uB:
1.1
3ko0F-6d6uB:
1.8		 3ko0C-6d6uB:
20.39
3ko0D-6d6uB:
20.39
3ko0E-6d6uB:
20.39
3ko0F-6d6uB:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_F_TFPF202_1
(PROTEIN S100-A4)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
(Homo
sapiens) 		5 / 11 LEU B 331
ILE B 335
PHE B 289
PHE B 296
SER B 241
 None
 1.31A 3ko0E-6d6uB:
1.1
3ko0F-6d6uB:
1.8
3ko0G-6d6uB:
1.9
3ko0H-6d6uB:
undetectable		 3ko0E-6d6uB:
20.39
3ko0F-6d6uB:
20.39
3ko0G-6d6uB:
20.39
3ko0H-6d6uB:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_H_TFPH202_1
(PROTEIN S100-A4)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
(Homo
sapiens) 		5 / 12 LEU B 331
ILE B 335
PHE B 289
PHE B 296
SER B 241
 None
 1.36A 3ko0G-6d6uB:
1.9
3ko0H-6d6uB:
undetectable
3ko0I-6d6uB:
undetectable
3ko0J-6d6uB:
undetectable		 3ko0G-6d6uB:
20.39
3ko0H-6d6uB:
20.39
3ko0I-6d6uB:
20.39
3ko0J-6d6uB:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_I_TFPI202_1
(PROTEIN S100-A4)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
BETA-2,GAMMA-AMINOBU
TYRIC ACID RECEPTOR
SUBUNIT BETA-2
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
GAMMA-2,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT GAMMA-2
(Homo
sapiens) 		5 / 12 ASP A  48
SER A  46
LEU E 167
PHE E 113
ILE E 147
 None
 1.16A 3ko0G-6d6uA:
1.8
3ko0H-6d6uA:
undetectable
3ko0I-6d6uA:
undetectable
3ko0J-6d6uA:
undetectable		 3ko0G-6d6uA:
19.80
3ko0H-6d6uA:
19.80
3ko0I-6d6uA:
19.80
3ko0J-6d6uA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_L_TFPL202_1
(PROTEIN S100-A4)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
BETA-2,GAMMA-AMINOBU
TYRIC ACID RECEPTOR
SUBUNIT BETA-2
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
GAMMA-2,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT GAMMA-2
(Homo
sapiens) 		5 / 12 LEU E 167
PHE E 113
ILE E 147
ASP A  48
SER A  46
 None
 1.22A 3ko0K-6d6uE:
undetectable
3ko0L-6d6uE:
undetectable
3ko0M-6d6uE:
undetectable
3ko0N-6d6uE:
undetectable		 3ko0K-6d6uE:
21.15
3ko0L-6d6uE:
21.15
3ko0M-6d6uE:
21.15
3ko0N-6d6uE:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_N_TFPN202_1
(PROTEIN S100-A4)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
(Homo
sapiens) 		5 / 11 SER B 241
PHE B 296
LEU B 331
ILE B 335
PHE B 289
 None
 1.33A 3ko0K-6d6uB:
undetectable
3ko0L-6d6uB:
1.8
3ko0M-6d6uB:
undetectable
3ko0N-6d6uB:
1.8		 3ko0K-6d6uB:
20.39
3ko0L-6d6uB:
20.39
3ko0M-6d6uB:
20.39
3ko0N-6d6uB:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_O_TFPO202_1
(PROTEIN S100-A4)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
(Homo
sapiens) 		5 / 11 LEU B 331
ILE B 335
PHE B 289
PHE B 296
SER B 241
 None
 1.37A 3ko0O-6d6uB:
undetectable
3ko0P-6d6uB:
undetectable
3ko0Q-6d6uB:
1.9
3ko0R-6d6uB:
undetectable		 3ko0O-6d6uB:
20.39
3ko0P-6d6uB:
20.39
3ko0Q-6d6uB:
20.39
3ko0R-6d6uB:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_O_TFPO202_1
(PROTEIN S100-A4)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
BETA-2,GAMMA-AMINOBU
TYRIC ACID RECEPTOR
SUBUNIT BETA-2
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
GAMMA-2,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT GAMMA-2
(Homo
sapiens) 		5 / 11 LEU E 167
PHE E 113
ILE E 147
ASP A  48
SER A  46
 None
 1.17A 3ko0O-6d6uE:
undetectable
3ko0P-6d6uE:
undetectable
3ko0Q-6d6uE:
undetectable
3ko0R-6d6uE:
undetectable		 3ko0O-6d6uE:
21.15
3ko0P-6d6uE:
21.15
3ko0Q-6d6uE:
21.15
3ko0R-6d6uE:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_Q_TFPQ202_1
(PROTEIN S100-A4)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
(Homo
sapiens) 		5 / 10 PHE B 296
SER B 241
LEU B 331
ILE B 335
PHE B 289
 None
 1.37A 3ko0O-6d6uB:
undetectable
3ko0P-6d6uB:
undetectable
3ko0Q-6d6uB:
1.9
3ko0R-6d6uB:
undetectable		 3ko0O-6d6uB:
20.39
3ko0P-6d6uB:
20.39
3ko0Q-6d6uB:
20.39
3ko0R-6d6uB:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_T_TFPT202_1
(PROTEIN S100-A4)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
(Homo
sapiens) 		5 / 11 SER B 241
PHE B 296
LEU B 331
ILE B 335
PHE B 289
 None
 1.36A 3ko0Q-6d6uB:
1.9
3ko0R-6d6uB:
undetectable
3ko0S-6d6uB:
undetectable
3ko0T-6d6uB:
1.8		 3ko0Q-6d6uB:
20.39
3ko0R-6d6uB:
20.39
3ko0S-6d6uB:
20.39
3ko0T-6d6uB:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_T_TFPT202_1
(PROTEIN S100-A4)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
BETA-2,GAMMA-AMINOBU
TYRIC ACID RECEPTOR
SUBUNIT BETA-2
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
GAMMA-2,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT GAMMA-2
(Homo
sapiens) 		5 / 11 ASP A  48
SER A  46
LEU E 167
PHE E 113
ILE E 147
 None
 1.12A 3ko0Q-6d6uA:
1.9
3ko0R-6d6uA:
1.8
3ko0S-6d6uA:
undetectable
3ko0T-6d6uA:
1.8		 3ko0Q-6d6uA:
19.80
3ko0R-6d6uA:
19.80
3ko0S-6d6uA:
19.80
3ko0T-6d6uA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VT7_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
(Homo
sapiens) 		4 / 4 LEU B 143
ILE B 223
TYR B 344
TYR B 191
 None
 1.49A 3vt7A-6d6uB:
undetectable		 3vt7A-6d6uB:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_D_ADND301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
(Homo
sapiens) 		5 / 10 ALA B  91
LEU B  75
LEU B 119
ASN B  87
ILE B 121
 None
 1.06A 3wdmD-6d6uB:
undetectable		 3wdmD-6d6uB:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7B_C_ACTC513_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
(Homo
sapiens) 		3 / 3 TYR B 191
HIS B 151
ARG B 221
 None
 1.19A 4e7bC-6d6uB:
undetectable		 4e7bC-6d6uB:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA504_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
BETA-2,GAMMA-AMINOBU
TYRIC ACID RECEPTOR
SUBUNIT BETA-2
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
GAMMA-2,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT GAMMA-2
(Homo
sapiens) 		4 / 8 PHE E 306
ILE A 232
THR A 256
THR A 260
 None
None
Y01  E 401 ( 4.4A)
None
 0.86A 4em2A-6d6uE:
undetectable		 4em2A-6d6uE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F3T_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
BETA-2,GAMMA-AMINOBU
TYRIC ACID RECEPTOR
SUBUNIT BETA-2
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
GAMMA-2,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT GAMMA-2
(Homo
sapiens;
Homo
sapiens) 		4 / 6 LEU A 272
TYR E 292
GLU A  52
TYR A 143
 None
 1.20A 4f3tA-6d6uA:
undetectable		 4f3tA-6d6uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTJ_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
GAMMA-2,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT GAMMA-2
(Homo
sapiens) 		5 / 12 ILE E  62
LEU E 206
PHE E 227
ILE E  74
THR E 193
 None
 1.00A 4ptjA-6d6uE:
undetectable		 4ptjA-6d6uE:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
BETA-2,GAMMA-AMINOBU
TYRIC ACID RECEPTOR
SUBUNIT BETA-2
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
GAMMA-2,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT GAMMA-2
(Homo
sapiens;
Homo
sapiens) 		4 / 6 LEU A 272
TYR E 292
GLU A  52
TYR A 143
 None
 1.22A 4z4gA-6d6uA:
undetectable		 4z4gA-6d6uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE1_A_X2NA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
IGG2B FAB HEAVY
CHAIN
(Homo
sapiens;
Mus
musculus) 		4 / 5 VAL B 212
TYR J  33
ILE J  29
THR B 126
 None
 1.27A 4ze1A-6d6uB:
undetectable		 4ze1A-6d6uB:
10.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_B_SAMB301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
(Homo
sapiens) 		5 / 12 ALA B 182
THR B 130
GLN B  68
PHE B  46
THR B  43
 None
ABU  A 405 (-3.1A)
None
None
None
 1.29A 5hfjB-6d6uB:
undetectable		 5hfjB-6d6uB:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_C_SAMC301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
(Homo
sapiens) 		5 / 12 ALA B 182
THR B 130
GLN B  68
PHE B  46
THR B  43
 None
ABU  A 405 (-3.1A)
None
None
None
 1.25A 5hfjC-6d6uB:
undetectable		 5hfjC-6d6uB:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_G_SAMG301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
(Homo
sapiens) 		5 / 12 ALA B 182
THR B 130
GLN B  68
PHE B  46
THR B  43
 None
ABU  A 405 (-3.1A)
None
None
None
 1.24A 5hfjG-6d6uB:
undetectable		 5hfjG-6d6uB:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IL1_A_SAMA601_0
(METTL3)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
BETA-2,GAMMA-AMINOBU
TYRIC ACID RECEPTOR
SUBUNIT BETA-2
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
(Homo
sapiens;
Homo
sapiens) 		5 / 12 ASP A 163
ARG A  28
PRO A  94
ASN B 116
GLY A 158
 None
 1.33A 5il1A-6d6uA:
undetectable		 5il1A-6d6uA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MTH_B_ACTB302_0
(ANTIBODY FAB HEAVY
CHAIN
ANTIBODY FAB LIGHT
CHAIN)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
BETA-2,GAMMA-AMINOBU
TYRIC ACID RECEPTOR
SUBUNIT BETA-2
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
GAMMA-2,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT GAMMA-2
(Homo
sapiens;
Homo
sapiens) 		4 / 5 GLU A  52
TYR A 143
TYR E 292
ARG A 216
 None
 1.30A 5mthA-6d6uA:
1.6
5mthB-6d6uA:
1.2		 5mthA-6d6uA:
undetectable
5mthB-6d6uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MTH_H_ACTH304_0
(ANTIBODY FAB HEAVY
CHAIN
ANTIBODY FAB LIGHT
CHAIN)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
BETA-2,GAMMA-AMINOBU
TYRIC ACID RECEPTOR
SUBUNIT BETA-2
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
GAMMA-2,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT GAMMA-2
(Homo
sapiens;
Homo
sapiens) 		4 / 5 GLU A  52
TYR A 143
TYR E 292
ARG A 216
 None
 1.27A 5mthH-6d6uA:
2.0
5mthL-6d6uA:
3.0		 5mthH-6d6uA:
undetectable
5mthL-6d6uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UBB_A_SAMA301_0
(ALPHA N-TERMINAL
PROTEIN
METHYLTRANSFERASE 1B)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
BETA-2,GAMMA-AMINOBU
TYRIC ACID RECEPTOR
SUBUNIT BETA-2
(Homo
sapiens) 		6 / 12 SER A  73
LEU A  72
GLN A  65
VAL A 124
HIS A 119
LEU A 118
 None
None
None
None
NAG  A 404 (-3.9A)
None
 1.31A 5ubbA-6d6uA:
undetectable		 5ubbA-6d6uA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC3_A_486A801_2
(GLUCOCORTICOID
RECEPTOR)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
GAMMA-2,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT GAMMA-2
(Homo
sapiens) 		4 / 5 LEU E 246
LEU E 250
MET E 276
TYR E 241
 None
 1.46A 5uc3A-6d6uE:
undetectable		 5uc3A-6d6uE:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6J_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
GAMMA-2,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT GAMMA-2
(Homo
sapiens) 		5 / 12 ILE E  62
LEU E 206
PHE E 227
ILE E  74
THR E 193
 None
 0.99A 5z6jA-6d6uE:
undetectable		 5z6jA-6d6uE:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_B_RFPB502_2
(RIFAMPIN
MONOOXYGENASE)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
BETA-2,GAMMA-AMINOBU
TYRIC ACID RECEPTOR
SUBUNIT BETA-2
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
GAMMA-2,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT GAMMA-2
(Homo
sapiens) 		4 / 6 VAL A  16
LEU E  87
ARG E  85
PRO E  44
 None
 1.27A 6brdB-6d6uA:
undetectable		 6brdB-6d6uA:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_A_EY4A501_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
(Homo
sapiens) 		4 / 5 GLN B 242
VAL B 243
TRP B 246
PRO B 330
 None
 1.23A 6cduA-6d6uB:
26.2
6cduB-6d6uB:
26.0		 6cduA-6d6uB:
undetectable
6cduB-6d6uB:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CDU_G_EY4G502_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
(Homo
sapiens) 		4 / 8 GLN B 242
VAL B 243
TRP B 246
PRO B 330
 None
 0.96A 6cduG-6d6uB:
19.4
6cduH-6d6uB:
26.1		 6cduG-6d6uB:
46.83
6cduH-6d6uB:
46.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D6T_D_FYPD406_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
HUMAN GABA-A
RECEPTOR SUBUNIT
GAMMA-2)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
(Homo
sapiens) 		5 / 11 HIS B 102
TYR B 160
SER B 206
THR B 207
TYR B 210
 None
 0.66A 6d6tD-6d6uB:
37.4
6d6tE-6d6uB:
27.9		 6d6tD-6d6uB:
undetectable
6d6tE-6d6uB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D6T_D_FYPD406_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
HUMAN GABA-A
RECEPTOR SUBUNIT
GAMMA-2)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
GAMMA-2,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT GAMMA-2
(Homo
sapiens) 		5 / 11 ASP E  56
TYR E  58
PHE E  77
ALA E  79
THR E 142
 None
 0.31A 6d6tD-6d6uE:
29.6
6d6tE-6d6uE:
31.1		 6d6tD-6d6uE:
undetectable
6d6tE-6d6uE:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D6T_D_FYPD406_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
HUMAN GABA-A
RECEPTOR SUBUNIT
GAMMA-2)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
BETA-2,GAMMA-AMINOBU
TYRIC ACID RECEPTOR
SUBUNIT BETA-2
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
(Homo
sapiens;
Homo
sapiens) 		7 / 11 TYR A 157
SER A 201
THR A 202
TYR A 205
ASP B  44
PHE B  65
THR B 130
 ABU  A 405 (-4.4A)
None
ABU  A 405 (-3.1A)
ABU  A 405 (-3.0A)
None
ABU  A 405 (-4.6A)
ABU  A 405 (-3.1A)
 0.67A 6d6tD-6d6uA:
33.9
6d6tE-6d6uA:
27.2		 6d6tD-6d6uA:
undetectable
6d6tE-6d6uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D6U_D_FYPD410_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
GAMMA-2,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT GAMMA-2)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
BETA-2,GAMMA-AMINOBU
TYRIC ACID RECEPTOR
SUBUNIT BETA-2
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
(Homo
sapiens;
Homo
sapiens) 		5 / 9 TYR A 157
SER A 201
TYR A 205
ASP B  44
THR B 130
 ABU  A 405 (-4.4A)
None
ABU  A 405 (-3.0A)
None
ABU  A 405 (-3.1A)
 0.81A 6d6uD-6d6uA:
19.5
6d6uE-6d6uA:
17.6		 6d6uD-6d6uA:
undetectable
6d6uE-6d6uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECT_A_SAMA1300_1
(STIE PROTEIN)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
BETA-2,GAMMA-AMINOBU
TYRIC ACID RECEPTOR
SUBUNIT BETA-2
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
GAMMA-2,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT GAMMA-2
(Homo
sapiens;
Homo
sapiens) 		4 / 5 THR A 123
THR E 216
GLN A  64
ASP E 219
 None
 1.30A 6ectA-6d6uA:
undetectable		 6ectA-6d6uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECX_A_SAMA1301_1
(STIE PROTEIN)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
BETA-2,GAMMA-AMINOBU
TYRIC ACID RECEPTOR
SUBUNIT BETA-2
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
GAMMA-2,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT GAMMA-2
(Homo
sapiens;
Homo
sapiens) 		4 / 5 THR A 123
THR E 216
GLN A  64
ASP E 219
 None
 1.34A 6ecxA-6d6uA:
undetectable		 6ecxA-6d6uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBV_D_FI8D1904_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
(Homo
sapiens) 		4 / 8 MET B 236
ILE B 235
THR B 265
SER B 270
 None
 0.77A 6fbvC-6d6uB:
undetectable		 6fbvC-6d6uB:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HUO_D_08HD501_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT GAMMA-2)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
(Homo
sapiens) 		5 / 8 PHE B 100
HIS B 102
VAL B 203
SER B 205
TYR B 210
 None
 0.69A 6huoC-6d6uB:
33.4
6huoD-6d6uB:
35.1		 6huoC-6d6uB:
20.22
6huoD-6d6uB:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HUP_B_DZPB502_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT BETA-3)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
BETA-2,GAMMA-AMINOBU
TYRIC ACID RECEPTOR
SUBUNIT BETA-2
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
(Homo
sapiens;
Homo
sapiens) 		6 / 11 ILE B 228
LEU B 232
PRO B 233
MET B 236
THR B 237
THR A 262
 None
 0.82A 6hupA-6d6uB:
34.7
6hupB-6d6uB:
33.7		 6hupA-6d6uB:
100.00
6hupB-6d6uB:
28.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HUP_B_DZPB502_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT BETA-3)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
BETA-2,GAMMA-AMINOBU
TYRIC ACID RECEPTOR
SUBUNIT BETA-2
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
(Homo
sapiens;
Homo
sapiens) 		6 / 11 ILE B 228
LEU B 232
PRO B 233
THR B 237
THR A 262
ASN A 265
 None
 0.94A 6hupA-6d6uB:
34.7
6hupB-6d6uB:
33.7		 6hupA-6d6uB:
100.00
6hupB-6d6uB:
28.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HUP_B_DZPB502_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT BETA-3)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
BETA-2,GAMMA-AMINOBU
TYRIC ACID RECEPTOR
SUBUNIT BETA-2
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
(Homo
sapiens;
Homo
sapiens) 		6 / 11 ILE B 228
LEU B 232
PRO B 233
THR B 237
THR A 262
LEU A 285
 None
 1.31A 6hupA-6d6uB:
34.7
6hupB-6d6uB:
33.7		 6hupA-6d6uB:
100.00
6hupB-6d6uB:
28.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HUP_B_DZPB502_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT BETA-3)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
BETA-2,GAMMA-AMINOBU
TYRIC ACID RECEPTOR
SUBUNIT BETA-2
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
(Homo
sapiens;
Homo
sapiens) 		6 / 11 ILE B 228
LEU B 232
PRO B 233
THR B 237
THR A 266
LEU A 285
 None
 1.04A 6hupA-6d6uB:
34.7
6hupB-6d6uB:
33.7		 6hupA-6d6uB:
100.00
6hupB-6d6uB:
28.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HUP_B_DZPB502_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT BETA-3)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
BETA-2,GAMMA-AMINOBU
TYRIC ACID RECEPTOR
SUBUNIT BETA-2
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
(Homo
sapiens;
Homo
sapiens) 		6 / 11 ILE B 228
PRO B 233
THR B 237
THR A 262
ASN A 265
PHE A 289
 None
 1.26A 6hupA-6d6uB:
34.7
6hupB-6d6uB:
33.7		 6hupA-6d6uB:
100.00
6hupB-6d6uB:
28.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HUP_B_DZPB502_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT BETA-3)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
BETA-2,GAMMA-AMINOBU
TYRIC ACID RECEPTOR
SUBUNIT BETA-2
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
(Homo
sapiens;
Homo
sapiens) 		6 / 11 ILE B 228
PRO B 233
THR B 237
THR A 262
LEU A 285
PHE A 289
 None
 1.35A 6hupA-6d6uB:
34.7
6hupB-6d6uB:
33.7		 6hupA-6d6uB:
100.00
6hupB-6d6uB:
28.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HUP_B_DZPB502_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT BETA-3)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
BETA-2,GAMMA-AMINOBU
TYRIC ACID RECEPTOR
SUBUNIT BETA-2
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
(Homo
sapiens;
Homo
sapiens) 		6 / 11 ILE B 228
THR B 237
MET A 261
THR A 262
ASN A 265
PHE A 289
 None
 1.28A 6hupA-6d6uB:
34.7
6hupB-6d6uB:
33.7		 6hupA-6d6uB:
100.00
6hupB-6d6uB:
28.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HUP_B_DZPB502_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT BETA-3)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
BETA-2,GAMMA-AMINOBU
TYRIC ACID RECEPTOR
SUBUNIT BETA-2
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
(Homo
sapiens;
Homo
sapiens) 		6 / 11 ILE B 228
THR B 237
MET A 261
THR A 262
LEU A 285
PHE A 289
 None
 1.34A 6hupA-6d6uB:
34.7
6hupB-6d6uB:
33.7		 6hupA-6d6uB:
100.00
6hupB-6d6uB:
28.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HUP_B_DZPB502_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT BETA-3)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
BETA-2,GAMMA-AMINOBU
TYRIC ACID RECEPTOR
SUBUNIT BETA-2
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
(Homo
sapiens;
Homo
sapiens) 		5 / 11 PRO B 233
THR B 237
THR A 266
LEU A 285
MET A 286
 None
 1.14A 6hupA-6d6uB:
34.7
6hupB-6d6uB:
33.7		 6hupA-6d6uB:
100.00
6hupB-6d6uB:
28.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HUP_D_DZPD2001_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT GAMMA-2)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
(Homo
sapiens) 		5 / 9 PHE B 100
HIS B 102
TYR B 160
VAL B 203
TYR B 210
 None
 0.65A 6hupC-6d6uB:
33.5
6hupD-6d6uB:
35.0		 6hupC-6d6uB:
20.22
6hupD-6d6uB:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HUP_D_DZPD2001_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT GAMMA-2)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
(Homo
sapiens) 		5 / 9 PHE B 100
TYR B 160
VAL B 203
SER B 205
TYR B 210
 None
 0.87A 6hupC-6d6uB:
33.5
6hupD-6d6uB:
35.0		 6hupC-6d6uB:
20.22
6hupD-6d6uB:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HUP_E_DZPE502_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT BETA-3)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
BETA-2,GAMMA-AMINOBU
TYRIC ACID RECEPTOR
SUBUNIT BETA-2
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
(Homo
sapiens;
Homo
sapiens) 		6 / 10 LEU B 232
PRO B 233
LEU B 269
THR A 266
LEU A 285
MET A 286
 None
 1.23A 6hupD-6d6uB:
35.0
6hupE-6d6uB:
33.2		 6hupD-6d6uB:
100.00
6hupE-6d6uB:
28.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HUP_E_DZPE502_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT BETA-3)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
BETA-2,GAMMA-AMINOBU
TYRIC ACID RECEPTOR
SUBUNIT BETA-2
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
(Homo
sapiens;
Homo
sapiens) 		6 / 10 LEU B 232
PRO B 233
MET A 261
ASN A 265
LEU A 285
MET A 286
 None
 1.35A 6hupD-6d6uB:
35.0
6hupE-6d6uB:
33.2		 6hupD-6d6uB:
100.00
6hupE-6d6uB:
28.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HUP_E_DZPE502_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT BETA-3)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
BETA-2,GAMMA-AMINOBU
TYRIC ACID RECEPTOR
SUBUNIT BETA-2
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
(Homo
sapiens;
Homo
sapiens) 		7 / 10 LEU B 232
PRO B 233
MET A 261
THR A 262
ASN A 265
LEU A 285
PHE A 289
 None
 1.00A 6hupD-6d6uB:
35.0
6hupE-6d6uB:
33.2		 6hupD-6d6uB:
100.00
6hupE-6d6uB:
28.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HUP_E_DZPE502_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT BETA-3)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
BETA-2,GAMMA-AMINOBU
TYRIC ACID RECEPTOR
SUBUNIT BETA-2
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
(Homo
sapiens;
Homo
sapiens) 		5 / 10 LEU B 232
PRO B 233
MET B 236
ASN A 265
MET A 286
 None
 1.26A 6hupD-6d6uB:
35.0
6hupE-6d6uB:
33.2		 6hupD-6d6uB:
100.00
6hupE-6d6uB:
28.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HUP_E_DZPE502_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT BETA-3)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
BETA-2,GAMMA-AMINOBU
TYRIC ACID RECEPTOR
SUBUNIT BETA-2
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
(Homo
sapiens;
Homo
sapiens) 		5 / 10 LEU B 232
PRO B 233
MET B 236
LEU B 269
MET A 286
 None
 1.31A 6hupD-6d6uB:
35.0
6hupE-6d6uB:
33.2		 6hupD-6d6uB:
100.00
6hupE-6d6uB:
28.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HUP_E_DZPE502_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT BETA-3)		 6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
BETA-2,GAMMA-AMINOBU
TYRIC ACID RECEPTOR
SUBUNIT BETA-2
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
(Homo
sapiens;
Homo
sapiens) 		6 / 10 LEU B 232
PRO B 233
MET B 236
THR A 262
ASN A 265
PHE A 289
 None
 1.13A 6hupD-6d6uB:
35.0
6hupE-6d6uB:
33.2		 6hupD-6d6uB:
100.00
6hupE-6d6uB:
28.75