SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6d9y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_A_DVAA6_0
(GRAMICIDIN A)		 6d9y SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR
(Paraburkholderia
phymatum) 		3 / 3 ALA A  73
VAL A  75
TRP A  38
 None
 0.81A 1nt5A-6d9yA:
undetectable		 1nt5A-6d9yA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_B_DVAB6_0
(GRAMICIDIN A)		 6d9y SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR
(Paraburkholderia
phymatum) 		3 / 3 ALA A  73
VAL A  75
TRP A  38
 None
 0.81A 1nt5B-6d9yA:
undetectable		 1nt5B-6d9yA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S19_A_MC9A500_0
(VITAMIN D3 RECEPTOR)		 6d9y SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR
(Paraburkholderia
phymatum) 		5 / 12 LEU A 164
LEU A 122
VAL A 123
VAL A 115
LEU A  40
 None
 1.12A 1s19A-6d9yA:
undetectable		 1s19A-6d9yA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_A_SAMA301_1
(HEMK PROTEIN)		 6d9y SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR
(Paraburkholderia
phymatum) 		4 / 4 THR A 192
GLY A  16
ASP A  39
ALA A  92
 None
 1.23A 1sg9A-6d9yA:
7.1		 1sg9A-6d9yA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T86_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 6d9y SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR
(Paraburkholderia
phymatum) 		5 / 9 THR A  78
LEU A  88
VAL A  12
VAL A  63
VAL A  61
 None
 1.34A 1t86B-6d9yA:
undetectable		 1t86B-6d9yA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UAY_A_ADNA1001_1
(TYPE II
3-HYDROXYACYL-COA
DEHYDROGENASE)		 6d9y SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR
(Paraburkholderia
phymatum) 		7 / 11 GLY A  15
ALA A  17
ASP A  39
LEU A  40
ASP A  64
ALA A  92
VAL A 115
 None
 0.51A 1uayA-6d9yA:
29.9		 1uayA-6d9yA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UAY_B_ADNB1002_1
(TYPE II
3-HYDROXYACYL-COA
DEHYDROGENASE)		 6d9y SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR
(Paraburkholderia
phymatum) 		7 / 10 GLY A  15
ALA A  17
ASP A  39
LEU A  40
ASP A  64
ALA A  92
VAL A 115
 None
 0.54A 1uayB-6d9yA:
30.5		 1uayB-6d9yA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_B_SAMB801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 6d9y SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR
(Paraburkholderia
phymatum) 		4 / 8 ILE A 142
ASN A 116
SER A 160
SER A 144
 None
 1.09A 2zw9B-6d9yA:
6.4		 2zw9B-6d9yA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAT_A_BEZA1000_0
(BENZOATE-COENZYME A
LIGASE)		 6d9y SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR
(Paraburkholderia
phymatum) 		4 / 7 ALA A  92
GLY A  19
GLY A  16
ILE A  13
 None
 0.65A 4eatA-6d9yA:
3.3		 4eatA-6d9yA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EK1_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 6d9y SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR
(Paraburkholderia
phymatum) 		5 / 9 THR A  78
LEU A  88
VAL A  12
VAL A  63
VAL A  61
 None
 1.36A 4ek1B-6d9yA:
undetectable		 4ek1B-6d9yA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EOH_A_TEPA402_1
(PYRIDOXAL KINASE)		 6d9y SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR
(Paraburkholderia
phymatum) 		4 / 5 GLY A  15
THR A  66
VAL A  63
ASP A  39
 None
 0.96A 4eohA-6d9yA:
5.1		 4eohA-6d9yA:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGH_A_SAMA401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)		 6d9y SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR
(Paraburkholderia
phymatum) 		5 / 11 GLY A  15
GLY A  16
ASP A  39
LEU A  40
ASP A  64
 None
 0.81A 4pghA-6d9yA:
6.4		 4pghA-6d9yA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDR_A_ADNA402_1
(FAD:PROTEIN FMN
TRANSFERASE)		 6d9y SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR
(Paraburkholderia
phymatum) 		5 / 12 LEU A  40
ASP A  39
GLY A  15
ALA A  92
ILE A  94
 None
 1.00A 4xdrA-6d9yA:
undetectable		 4xdrA-6d9yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z69_A_DIFA1007_1
(SERUM ALBUMIN)		 6d9y SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR
(Paraburkholderia
phymatum) 		5 / 9 ARG A  30
LEU A  29
LEU A  37
ILE A  13
ALA A  23
 None
 1.41A 4z69A-6d9yA:
undetectable		 4z69A-6d9yA:
9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJZ_A_BEZA1001_0
(BENZOATE-COENZYME A
LIGASE)		 6d9y SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR
(Paraburkholderia
phymatum) 		4 / 8 ALA A 162
GLY A 147
ALA A 146
GLY A 150
 None
 0.68A 4zjzA-6d9yA:
undetectable		 4zjzA-6d9yA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HJI_A_ADNA401_1
(TRNA
(GUANINE(37)-N1)-MET
HYLTRANSFERASE TRM5A)		 6d9y SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR
(Paraburkholderia
phymatum) 		5 / 11 LEU A 122
TYR A 121
GLY A 163
ILE A 118
ASP A 114
 None
None
None
OXM  A 303 ( 4.7A)
OXM  A 303 (-4.6A)
 1.38A 5hjiA-6d9yA:
7.1		 5hjiA-6d9yA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		 6d9y SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR
(Paraburkholderia
phymatum) 		5 / 9 ALA A 146
ALA A 159
SER A 158
VAL A 112
GLY A 163
 None
 1.23A 6bklA-6d9yA:
undetectable
6bklB-6d9yA:
undetectable
6bklC-6d9yA:
undetectable
6bklD-6d9yA:
undetectable		 6bklA-6d9yA:
undetectable
6bklB-6d9yA:
undetectable
6bklC-6d9yA:
undetectable
6bklD-6d9yA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQ4_A_ADNA401_1
(THERMOSPERMINE
SYNTHASE ACAULIS
PROTEIN)		 6d9y SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR
(Paraburkholderia
phymatum) 		5 / 12 GLY A  16
ASP A  41
LEU A  37
ALA A  60
LEU A  52
 None
 0.92A 6bq4A-6d9yA:
7.4		 6bq4A-6d9yA:
18.75