SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6day'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OHR_A_1UNA201_2
(ASPARTYLPROTEASE)		 6day DIHYDROPTEROATE
SYNTHASE
(Xanthomonas
albilineans) 		5 / 9 LEU A 220
VAL A 122
GLY A  63
ILE A  62
VAL A 142
 None
 0.95A 1ohrB-6dayA:
undetectable		 1ohrB-6dayA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q8J_A_C2FA801_0
(5-METHYLTETRAHYDROFO
LATE S-HOMOCYSTEINE
METHYLTRANSFERASE)		 6day DIHYDROPTEROATE
SYNTHASE
(Xanthomonas
albilineans) 		5 / 12 ASN A  27
ASP A 101
ASN A 120
ASP A 190
SER A 224
 SO4  A 403 (-3.1A)
None
None
None
None
 0.89A 1q8jA-6dayA:
12.1		 1q8jA-6dayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q8J_A_C2FA801_0
(5-METHYLTETRAHYDROFO
LATE S-HOMOCYSTEINE
METHYLTRANSFERASE)		 6day DIHYDROPTEROATE
SYNTHASE
(Xanthomonas
albilineans) 		5 / 12 ASP A 101
ASN A 120
ASP A 190
GLY A 222
SER A 224
 None
 0.74A 1q8jA-6dayA:
12.1		 1q8jA-6dayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YCJ_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 6day DIHYDROPTEROATE
SYNTHASE
(Xanthomonas
albilineans) 		5 / 12 ASP A  61
ASN A 120
ASP A 190
GLY A 222
SER A 224
 None
 1.27A 2ycjA-6dayA:
21.6		 2ycjA-6dayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YCJ_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 6day DIHYDROPTEROATE
SYNTHASE
(Xanthomonas
albilineans) 		5 / 12 ASP A 101
ASN A 120
ASP A 190
GLY A 222
SER A 224
 None
 0.82A 2ycjA-6dayA:
21.6		 2ycjA-6dayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_B_THHB643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 6day DIHYDROPTEROATE
SYNTHASE
(Xanthomonas
albilineans) 		5 / 12 ASP A  61
ASN A 120
VAL A 142
GLY A 222
SER A 224
 None
 1.24A 3k13B-6dayA:
19.1		 3k13B-6dayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_B_THHB643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 6day DIHYDROPTEROATE
SYNTHASE
(Xanthomonas
albilineans) 		5 / 12 ASP A 101
ASN A 120
VAL A 142
GLY A 222
SER A 224
 None
 0.64A 3k13B-6dayA:
19.1		 3k13B-6dayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU6_B_478B401_2
(PROTEASE)		 6day DIHYDROPTEROATE
SYNTHASE
(Xanthomonas
albilineans) 		5 / 10 LEU A 220
VAL A 122
GLY A  63
ILE A  62
VAL A 142
 None
 0.99A 3nu6B-6dayA:
undetectable		 3nu6B-6dayA:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P97_A_SAMA263_0
(NON-STRUCTURAL
PROTEIN 5)		 6day DIHYDROPTEROATE
SYNTHASE
(Xanthomonas
albilineans) 		5 / 12 GLY A  24
HIS A 249
ASP A 264
ASP A  61
ILE A  25
 None
None
None
None
SO4  A 403 (-4.3A)
 0.80A 3p97A-6dayA:
undetectable		 3p97A-6dayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJE_B_C2FB302_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 6day DIHYDROPTEROATE
SYNTHASE
(Xanthomonas
albilineans) 		6 / 12 ASP A  61
ASP A 101
ASN A 120
ASP A 190
GLY A 222
SER A 224
 None
 0.83A 4djeB-6dayA:
21.6		 4djeB-6dayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJF_B_C2FB300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 6day DIHYDROPTEROATE
SYNTHASE
(Xanthomonas
albilineans) 		5 / 12 ASP A  61
ASP A 101
ASN A 120
GLY A 222
SER A 224
 None
 0.77A 4djfB-6dayA:
8.3		 4djfB-6dayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PB1_A_RBVA501_1
(NUPC FAMILY PROTEIN)		 6day DIHYDROPTEROATE
SYNTHASE
(Xanthomonas
albilineans) 		5 / 12 GLY A 222
ALA A 221
PHE A 193
SER A 228
ILE A 229
 None
 1.10A 4pb1A-6dayA:
undetectable		 4pb1A-6dayA:
12.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		 6day DIHYDROPTEROATE
SYNTHASE
(Xanthomonas
albilineans) 		5 / 12 GLY A 222
ALA A 221
PHE A 193
SER A 228
ILE A 229
 None
 1.06A 4pd5A-6dayA:
undetectable		 4pd5A-6dayA:
12.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKM_A_SAMA311_0
(NS5 METHYL
TRANSFERASE)		 6day DIHYDROPTEROATE
SYNTHASE
(Xanthomonas
albilineans) 		5 / 12 GLY A  24
HIS A 249
ASP A 264
ASP A  61
ILE A  25
 None
None
None
None
SO4  A 403 (-4.3A)
 0.86A 5ikmA-6dayA:
undetectable		 5ikmA-6dayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR0_A_478A101_2
(PROTEASE E35D-APV)		 6day DIHYDROPTEROATE
SYNTHASE
(Xanthomonas
albilineans) 		5 / 9 LEU A 220
VAL A 122
GLY A  63
ILE A  62
VAL A 142
 None
 1.05A 5kr0B-6dayA:
undetectable		 5kr0B-6dayA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_A_SAMA301_0
(NS5)		 6day DIHYDROPTEROATE
SYNTHASE
(Xanthomonas
albilineans) 		5 / 12 GLY A  24
HIS A 249
ASP A 264
ASP A  61
ILE A  25
 None
None
None
None
SO4  A 403 (-4.3A)
 0.86A 5njvA-6dayA:
undetectable		 5njvA-6dayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_B_SAMB301_0
(NS5)		 6day DIHYDROPTEROATE
SYNTHASE
(Xanthomonas
albilineans) 		5 / 12 GLY A  24
HIS A 249
ASP A 264
ASP A  61
ILE A  25
 None
None
None
None
SO4  A 403 (-4.3A)
 0.87A 5njvB-6dayA:
undetectable		 5njvB-6dayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_D_SAMD301_0
(NS5)		 6day DIHYDROPTEROATE
SYNTHASE
(Xanthomonas
albilineans) 		5 / 12 GLY A  24
HIS A 249
ASP A 264
ASP A  61
ILE A  25
 None
None
None
None
SO4  A 403 (-4.3A)
 0.94A 5njvD-6dayA:
undetectable		 5njvD-6dayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_A_C2FA3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 6day DIHYDROPTEROATE
SYNTHASE
(Xanthomonas
albilineans) 		3 / 3 ASP A 101
ASN A 120
ASP A 190
 None
 0.47A 5vopA-6dayA:
19.2		 5vopA-6dayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_B_C2FB3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 6day DIHYDROPTEROATE
SYNTHASE
(Xanthomonas
albilineans) 		3 / 3 ASP A 101
ASN A 120
ASP A 190
 None
 0.41A 5vopB-6dayA:
19.1		 5vopB-6dayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_A_SAMA601_0
(NS5
METHYLTRANSFERASE)		 6day DIHYDROPTEROATE
SYNTHASE
(Xanthomonas
albilineans) 		5 / 12 GLY A  24
HIS A 249
ASP A 264
ASP A  61
ILE A  25
 None
None
None
None
SO4  A 403 (-4.3A)
 0.84A 5wz1A-6dayA:
undetectable		 5wz1A-6dayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_C_SAMC601_0
(NS5
METHYLTRANSFERASE)		 6day DIHYDROPTEROATE
SYNTHASE
(Xanthomonas
albilineans) 		5 / 12 GLY A  24
HIS A 249
ASP A 264
ASP A  61
ILE A  25
 None
None
None
None
SO4  A 403 (-4.3A)
 0.86A 5wz1C-6dayA:
undetectable		 5wz1C-6dayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_D_SAMD601_0
(NS5
METHYLTRANSFERASE)		 6day DIHYDROPTEROATE
SYNTHASE
(Xanthomonas
albilineans) 		5 / 12 GLY A  24
HIS A 249
ASP A 264
ASP A  61
ILE A  25
 None
None
None
None
SO4  A 403 (-4.3A)
 0.85A 5wz1D-6dayA:
undetectable		 5wz1D-6dayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_E_SAME601_0
(NS5
METHYLTRANSFERASE)		 6day DIHYDROPTEROATE
SYNTHASE
(Xanthomonas
albilineans) 		5 / 12 GLY A  24
HIS A 249
ASP A 264
ASP A  61
ILE A  25
 None
None
None
None
SO4  A 403 (-4.3A)
 0.87A 5wz1E-6dayA:
undetectable		 5wz1E-6dayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_F_SAMF601_0
(NS5
METHYLTRANSFERASE)		 6day DIHYDROPTEROATE
SYNTHASE
(Xanthomonas
albilineans) 		5 / 12 GLY A  24
HIS A 249
ASP A 264
ASP A  61
ILE A  25
 None
None
None
None
SO4  A 403 (-4.3A)
 0.86A 5wz1F-6dayA:
undetectable		 5wz1F-6dayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_G_SAMG601_0
(NS5
METHYLTRANSFERASE)		 6day DIHYDROPTEROATE
SYNTHASE
(Xanthomonas
albilineans) 		5 / 12 GLY A  24
HIS A 249
ASP A 264
ASP A  61
ILE A  25
 None
None
None
None
SO4  A 403 (-4.3A)
 0.85A 5wz1G-6dayA:
undetectable		 5wz1G-6dayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_H_SAMH601_0
(NS5
METHYLTRANSFERASE)		 6day DIHYDROPTEROATE
SYNTHASE
(Xanthomonas
albilineans) 		5 / 12 GLY A  24
HIS A 249
ASP A 264
ASP A  61
ILE A  25
 None
None
None
None
SO4  A 403 (-4.3A)
 0.86A 5wz1H-6dayA:
undetectable		 5wz1H-6dayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_A_SAMA601_0
(NS5 MTASE)		 6day DIHYDROPTEROATE
SYNTHASE
(Xanthomonas
albilineans) 		5 / 12 GLY A  24
HIS A 249
ASP A 264
ASP A  61
ILE A  25
 None
None
None
None
SO4  A 403 (-4.3A)
 0.90A 5wz2A-6dayA:
undetectable		 5wz2A-6dayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_B_SAMB601_0
(NS5 MTASE)		 6day DIHYDROPTEROATE
SYNTHASE
(Xanthomonas
albilineans) 		5 / 12 GLY A  24
HIS A 249
ASP A 264
ASP A  61
ILE A  25
 None
None
None
None
SO4  A 403 (-4.3A)
 0.87A 5wz2B-6dayA:
undetectable		 5wz2B-6dayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1431_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 6day DIHYDROPTEROATE
SYNTHASE
(Xanthomonas
albilineans) 		4 / 5 HIS A 263
ASP A 101
GLY A  63
ASN A  27
 SO4  A 403 (-4.2A)
None
None
SO4  A 403 (-3.1A)
 1.23A 5x7pB-6dayA:
2.1		 5x7pB-6dayA:
5.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBZ_B_ESTB602_1
(ESTROGEN RECEPTOR)		 6day DIHYDROPTEROATE
SYNTHASE
(Xanthomonas
albilineans) 		5 / 10 LEU A 220
ALA A 221
LEU A 260
ILE A 229
LEU A 206
 None
 1.48A 6cbzB-6dayA:
undetectable		 6cbzB-6dayA:
21.59