SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6db5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_B_SAMB6735_0
(16S RRNA METHYLASE)
6db5 HUMAN MONOCLONAL
ANTI-HIV-1 GP120 V3
ANTIBODY TA6 FAB
HEAVY CHAIN

(Homo
sapiens)
5 / 12 GLY H 106
GLY H 104
VAL H   5
ALA H   9
THR H 151
None
1.07A 3p2kB-6db5H:
undetectable
3p2kB-6db5H:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YSH_B_GLYB402_0
(GLYCINE OXIDASE)
6db5 HUMAN MONOCLONAL
ANTI-HIV-1 GP120 V3
ANTIBODY TA6 FAB
HEAVY CHAIN

(Homo
sapiens)
4 / 5 MET H  48
GLU H  46
TYR H  90
ARG H  66
None
1.49A 4yshB-6db5H:
undetectable
4yshB-6db5H:
undetectable