SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6dd6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RI4_A_SAMA299_0
(MRNA CAPPING ENZYME)		 6dd6 PHOTOLYASE PHRB
(Agrobacterium
tumefaciens) 		5 / 12 GLY A 275
ALA A 234
ASP A 281
GLN A  11
SER A  13
 None
 1.18A 1ri4A-6dd6A:
2.0		 1ri4A-6dd6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUV_A_VK3A4558_1
(PROTEIN YGIN)		 6dd6 PHOTOLYASE PHRB
(Agrobacterium
tumefaciens) 		4 / 7 TYR A 391
LEU A 337
MET A 351
ILE A 355
 FAD  A 601 (-3.7A)
None
None
None
 1.09A 1tuvA-6dd6A:
undetectable		 1tuvA-6dd6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDU_A_CIAA1003_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 6dd6 PHOTOLYASE PHRB
(Agrobacterium
tumefaciens) 		5 / 11 ILE A 126
VAL A 101
ALA A  18
ILE A  16
GLN A  11
 None
 1.28A 1uduA-6dd6A:
undetectable		 1uduA-6dd6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFM_A_TOPA1290_1
(PTERIDINE REDUCTASE
1)		 6dd6 PHOTOLYASE PHRB
(Agrobacterium
tumefaciens) 		5 / 9 PHE A 331
LEU A 378
LEU A 464
LEU A 477
TYR A 460
 None
 1.42A 2bfmA-6dd6A:
3.0
2bfmD-6dd6A:
3.7		 2bfmA-6dd6A:
undetectable
2bfmD-6dd6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIP_C_MTXC613_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 6dd6 PHOTOLYASE PHRB
(Agrobacterium
tumefaciens) 		5 / 12 ALA A 380
PHE A 456
SER A 427
THR A 346
TYR A 341
 None
SF4  A 603 ( 4.9A)
None
None
None
 1.12A 2oipC-6dd6A:
2.8		 2oipC-6dd6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_B_SAMB500_1
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 6dd6 PHOTOLYASE PHRB
(Agrobacterium
tumefaciens) 		4 / 6 THR A 232
ARG A 236
ASP A 201
THR A 204
 None
 0.99A 2okcB-6dd6A:
undetectable		 2okcB-6dd6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A9E_B_REAB1_1
(RETINOIC ACID
RECEPTOR ALPHA)		 6dd6 PHOTOLYASE PHRB
(Agrobacterium
tumefaciens) 		5 / 11 LEU A   8
ARG A 108
PHE A 116
VAL A   5
LEU A   4
 DLZ  A 602 (-3.7A)
DLZ  A 602 ( 4.8A)
None
None
None
 1.35A 3a9eB-6dd6A:
undetectable		 3a9eB-6dd6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJ3_A_MTXA605_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 6dd6 PHOTOLYASE PHRB
(Agrobacterium
tumefaciens) 		5 / 12 ALA A 380
PHE A 456
SER A 427
THR A 346
TYR A 341
 None
SF4  A 603 ( 4.9A)
None
None
None
 1.16A 3hj3A-6dd6A:
2.8		 3hj3A-6dd6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJ3_C_MTXC613_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 6dd6 PHOTOLYASE PHRB
(Agrobacterium
tumefaciens) 		5 / 12 ALA A 380
PHE A 456
SER A 427
THR A 346
TYR A 341
 None
SF4  A 603 ( 4.9A)
None
None
None
 1.13A 3hj3C-6dd6A:
undetectable		 3hj3C-6dd6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ITA_D_AICD501_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACC)		 6dd6 PHOTOLYASE PHRB
(Agrobacterium
tumefaciens) 		3 / 3 PRO A 405
PHE A 418
ALA A 321
 None
 0.72A 3itaD-6dd6A:
undetectable		 3itaD-6dd6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2O_C_AG2C1002_1
(BIOSYNTHETIC
ARGININE
DECARBOXYLASE)		 6dd6 PHOTOLYASE PHRB
(Agrobacterium
tumefaciens) 		4 / 8 LYS A 385
LEU A 404
ASP A 327
ASP A 324
 None
 0.92A 3n2oC-6dd6A:
undetectable
3n2oD-6dd6A:
undetectable		 3n2oC-6dd6A:
undetectable
3n2oD-6dd6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_D_CLMD221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6dd6 PHOTOLYASE PHRB
(Agrobacterium
tumefaciens) 		5 / 12 THR A 346
PHE A 340
TYR A 341
LEU A 459
ALA A 377
 None
 1.41A 3u9fD-6dd6A:
undetectable
3u9fE-6dd6A:
undetectable		 3u9fD-6dd6A:
undetectable
3u9fE-6dd6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZS_A_SAMA1475_1
(METHYLTRANSFERASE
WBDD)		 6dd6 PHOTOLYASE PHRB
(Agrobacterium
tumefaciens) 		3 / 3 ARG A 476
ASP A 254
GLN A 253
 None
 0.82A 4azsA-6dd6A:
2.2		 4azsA-6dd6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7N_A_ZMRA601_2
(NEURAMINIDASE)		 6dd6 PHOTOLYASE PHRB
(Agrobacterium
tumefaciens) 		3 / 3 ARG A 492
ARG A 468
TRP A 484
 None
 1.24A 4b7nA-6dd6A:
undetectable		 4b7nA-6dd6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_C_ZMRC1470_2
(NEURAMINIDASE)		 6dd6 PHOTOLYASE PHRB
(Agrobacterium
tumefaciens) 		3 / 3 ARG A 492
ARG A 468
TRP A 484
 None
 1.26A 4cpzC-6dd6A:
undetectable		 4cpzC-6dd6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_E_ZMRE1471_2
(NEURAMINIDASE)		 6dd6 PHOTOLYASE PHRB
(Agrobacterium
tumefaciens) 		3 / 3 ARG A 492
ARG A 468
TRP A 484
 None
 1.26A 4cpzE-6dd6A:
undetectable		 4cpzE-6dd6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_F_ZMRF1470_2
(NEURAMINIDASE)		 6dd6 PHOTOLYASE PHRB
(Agrobacterium
tumefaciens) 		3 / 3 ARG A 492
ARG A 468
TRP A 484
 None
 1.21A 4cpzF-6dd6A:
undetectable		 4cpzF-6dd6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_G_ZMRG1471_2
(NEURAMINIDASE)		 6dd6 PHOTOLYASE PHRB
(Agrobacterium
tumefaciens) 		3 / 3 ARG A 492
ARG A 468
TRP A 484
 None
 1.17A 4cpzG-6dd6A:
undetectable		 4cpzG-6dd6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_H_ZMRH1470_2
(NEURAMINIDASE)		 6dd6 PHOTOLYASE PHRB
(Agrobacterium
tumefaciens) 		3 / 3 ARG A 492
ARG A 468
TRP A 484
 None
 1.26A 4cpzH-6dd6A:
undetectable		 4cpzH-6dd6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8Z_A_BBIA402_1
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-3,
MITOCHONDRIAL)		 6dd6 PHOTOLYASE PHRB
(Agrobacterium
tumefaciens) 		4 / 5 PHE A 330
PHE A 413
LEU A 464
PRO A 480
 None
 1.15A 4o8zA-6dd6A:
2.3		 4o8zA-6dd6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_2
(THYROXINE-BINDING
GLOBULIN)		 6dd6 PHOTOLYASE PHRB
(Agrobacterium
tumefaciens) 		3 / 3 LEU A 133
ARG A 315
ARG A 311
 None
 0.85A 4yiaB-6dd6A:
undetectable		 4yiaB-6dd6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 6dd6 PHOTOLYASE PHRB
(Agrobacterium
tumefaciens) 		4 / 5 ALA A 180
ARG A 305
ALA A 299
GLU A 301
 None
 1.47A 5a06C-6dd6A:
2.5
5a06D-6dd6A:
2.4		 5a06C-6dd6A:
undetectable
5a06D-6dd6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_2_BEZ2801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 6dd6 PHOTOLYASE PHRB
(Agrobacterium
tumefaciens) 		4 / 4 LEU A 280
ARG A 311
ILE A 307
ILE A 272
 None
None
FAD  A 601 (-4.6A)
FAD  A 601 ( 4.6A)
 1.16A 5dzk2-6dd6A:
undetectable
5dzkM-6dd6A:
undetectable
5dzkN-6dd6A:
undetectable		 5dzk2-6dd6A:
undetectable
5dzkM-6dd6A:
undetectable
5dzkN-6dd6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G48_A_1FLA1375_1
(DNA POLYMERASE III
SUBUNIT BETA)		 6dd6 PHOTOLYASE PHRB
(Agrobacterium
tumefaciens) 		4 / 8 THR A 162
LEU A 164
ILE A 304
LEU A 165
 None
 0.84A 5g48A-6dd6A:
undetectable		 5g48A-6dd6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G48_B_1FLB1375_1
(DNA POLYMERASE III
SUBUNIT BETA)		 6dd6 PHOTOLYASE PHRB
(Agrobacterium
tumefaciens) 		5 / 9 LEU A 133
THR A 162
LEU A 164
ILE A 304
LEU A 165
 None
 0.97A 5g48B-6dd6A:
undetectable		 5g48B-6dd6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H3A_B_D16B401_1
(ORF70)		 6dd6 PHOTOLYASE PHRB
(Agrobacterium
tumefaciens) 		4 / 7 ILE A 317
GLY A 417
PHE A 418
TYR A 424
 None
 0.85A 5h3aB-6dd6A:
undetectable		 5h3aB-6dd6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH8_A_ACTA302_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6dd6 PHOTOLYASE PHRB
(Agrobacterium
tumefaciens) 		3 / 3 CYH A 454
MET A 348
ASN A 349
 SF4  A 603 (-1.8A)
None
None
 1.00A 5qh8A-6dd6A:
undetectable		 5qh8A-6dd6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA409_0
(UNCHARACTERIZED
PROTEIN KDOO)		 6dd6 PHOTOLYASE PHRB
(Agrobacterium
tumefaciens) 		3 / 3 ASP A  10
PHE A 132
ARG A 311
 DLZ  A 602 (-3.0A)
None
None
 0.88A 5yw0A-6dd6A:
undetectable		 5yw0A-6dd6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_A_8NUA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 6dd6 PHOTOLYASE PHRB
(Agrobacterium
tumefaciens) 		5 / 12 THR A 356
ILE A 359
PHE A 219
PHE A 340
LEU A 506
 None
 1.28A 6a93A-6dd6A:
undetectable		 6a93A-6dd6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC605_0
(ALPHA-AMYLASE)		 6dd6 PHOTOLYASE PHRB
(Agrobacterium
tumefaciens) 		4 / 8 TYR A 443
GLY A 428
ILE A 431
ASP A 439
 None
SF4  A 603 ( 4.4A)
SF4  A 603 (-3.5A)
None
 1.00A 6ag0C-6dd6A:
undetectable		 6ag0C-6dd6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_A_NOVA403_2
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 6dd6 PHOTOLYASE PHRB
(Agrobacterium
tumefaciens) 		4 / 6 PHE A 463
ARG A 468
LEU A 464
ALA A 425
 None
 0.96A 6b89B-6dd6A:
undetectable		 6b89B-6dd6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_A_GMJA301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 6dd6 PHOTOLYASE PHRB
(Agrobacterium
tumefaciens) 		5 / 12 LEU A  12
PHE A  83
VAL A  34
VAL A 109
TYR A 271
 None
DLZ  A 602 (-4.2A)
DLZ  A 602 (-4.6A)
None
None
 1.09A 6djzA-6dd6A:
undetectable		 6djzA-6dd6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_C_GMJC301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 6dd6 PHOTOLYASE PHRB
(Agrobacterium
tumefaciens) 		5 / 12 LEU A  12
PHE A  83
VAL A  34
VAL A 109
TYR A 271
 None
DLZ  A 602 (-4.2A)
DLZ  A 602 (-4.6A)
None
None
 1.12A 6djzC-6dd6A:
undetectable		 6djzC-6dd6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECT_A_SAMA1300_1
(STIE PROTEIN)		 6dd6 PHOTOLYASE PHRB
(Agrobacterium
tumefaciens) 		4 / 5 ARG A 108
THR A 102
GLN A  11
ASP A 125
 DLZ  A 602 ( 4.8A)
None
None
None
 1.48A 6ectA-6dd6A:
undetectable		 6ectA-6dd6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GQI_A_ACTA604_0
(CYCLOHEXANONE
MONOOXYGENASE FROM
THERMOCRISPUM
MUNICIPALE)		 6dd6 PHOTOLYASE PHRB
(Agrobacterium
tumefaciens) 		4 / 6 TRP A 142
GLY A 316
TYR A 313
GLU A 312
 None
 1.11A 6gqiA-6dd6A:
undetectable		 6gqiA-6dd6A:
undetectable