SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6dex'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3004_1
(SERUM ALBUMIN)		 6dex SUPPRESSOR OF
HYDROXYUREA
SENSITIVITY PROTEIN
1
(Eremothecium
gossypii) 		4 / 6 PHE A  74
GLU A  47
LEU A  50
VAL A  26
 None
 1.08A 1hk1A-6dexA:
undetectable		 1hk1A-6dexA:
9.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3002_1
(SERUM ALBUMIN)		 6dex SUPPRESSOR OF
HYDROXYUREA
SENSITIVITY PROTEIN
1
(Eremothecium
gossypii) 		4 / 8 GLN A 106
LEU A 107
TYR A 126
LEU A 114
 None
 1.20A 1hk2A-6dexA:
undetectable		 1hk2A-6dexA:
9.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NP1_A_HSMA303_1
(NITROPHORIN 1)		 6dex SUPPRESSOR OF
HYDROXYUREA
SENSITIVITY PROTEIN
1
(Eremothecium
gossypii) 		4 / 5 GLU A  28
LEU A  22
LEU A  25
LEU A  23
 None
 0.97A 1np1A-6dexA:
undetectable		 1np1A-6dexA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y7I_B_SALB503_1
(SALICYLIC
ACID-BINDING PROTEIN
2)		 6dex SUPPRESSOR OF
HYDROXYUREA
SENSITIVITY PROTEIN
1
SUPPRESSOR OF
HYDROXYUREA
SENSITIVITY PROTEIN
2
(Eremothecium
gossypii) 		5 / 10 LEU B 123
PHE B 124
TRP A 159
PHE B 105
LEU B 119
 None
 1.29A 1y7iB-6dexB:
undetectable		 1y7iB-6dexB:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6dex SUPPRESSOR OF
HYDROXYUREA
SENSITIVITY PROTEIN
2
(Eremothecium
gossypii) 		4 / 7 ARG B  36
LEU B  38
PHE B  39
PHE B 158
 None
 1.01A 2eimP-6dexB:
undetectable
2eimW-6dexB:
undetectable		 2eimP-6dexB:
undetectable
2eimW-6dexB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 6dex SUPPRESSOR OF
HYDROXYUREA
SENSITIVITY PROTEIN
2
(Eremothecium
gossypii) 		4 / 7 ARG B  36
LEU B  38
PHE B  39
PHE B 158
 None
 1.04A 3asnP-6dexB:
undetectable
3asnW-6dexB:
undetectable		 3asnP-6dexB:
undetectable
3asnW-6dexB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 6dex SUPPRESSOR OF
HYDROXYUREA
SENSITIVITY PROTEIN
2
(Eremothecium
gossypii) 		4 / 7 ARG B  36
LEU B  38
PHE B  39
PHE B 158
 None
 1.00A 3asoP-6dexB:
undetectable
3asoW-6dexB:
undetectable		 3asoP-6dexB:
undetectable
3asoW-6dexB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BSZ_E_RTLE177_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 6dex SUPPRESSOR OF
HYDROXYUREA
SENSITIVITY PROTEIN
2
(Eremothecium
gossypii) 		5 / 11 LEU B  15
ALA B 159
VAL B  26
LEU B  11
PHE B 174
 None
 1.25A 3bszE-6dexB:
undetectable		 3bszE-6dexB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8I_A_RO7A1_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)		 6dex SUPPRESSOR OF
HYDROXYUREA
SENSITIVITY PROTEIN
2
(Eremothecium
gossypii) 		4 / 7 GLN B 165
LEU B  46
LEU B  30
LEU B  95
 None
 0.72A 3g8iA-6dexB:
undetectable		 3g8iA-6dexB:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_A_LYAA514_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 6dex SUPPRESSOR OF
HYDROXYUREA
SENSITIVITY PROTEIN
2
(Eremothecium
gossypii) 		5 / 12 ALA B  42
PHE B  34
LEU B  30
THR B 166
LEU B  15
 None
 1.14A 3k2hA-6dexB:
undetectable		 3k2hA-6dexB:
10.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEG_A_T27A561_1
(P66 REVERSE
TRANSCRIPTASE)		 6dex SUPPRESSOR OF
HYDROXYUREA
SENSITIVITY PROTEIN
2
(Eremothecium
gossypii) 		5 / 12 PRO B  79
LEU B 164
PHE B 174
LEU B 171
TYR B  71
 None
 1.33A 3megA-6dexB:
undetectable		 3megA-6dexB:
10.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_D_CLMD221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6dex SUPPRESSOR OF
HYDROXYUREA
SENSITIVITY PROTEIN
2
(Eremothecium
gossypii) 		5 / 12 PHE B 136
LEU B  15
VAL B 170
PHE B 158
ALA B  42
 None
 1.29A 3u9fD-6dexB:
undetectable
3u9fE-6dexB:
undetectable		 3u9fD-6dexB:
undetectable
3u9fE-6dexB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_B_SALB1345_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 6dex SUPPRESSOR OF
HYDROXYUREA
SENSITIVITY PROTEIN
1
(Eremothecium
gossypii) 		4 / 8 LEU A  23
PHE A  46
VAL A 143
ALA A  42
 None
 0.90A 3uniB-6dexA:
undetectable		 3uniB-6dexA:
5.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 6dex SUPPRESSOR OF
HYDROXYUREA
SENSITIVITY PROTEIN
2
(Eremothecium
gossypii) 		4 / 6 ARG B  36
LEU B  38
PHE B  39
PHE B 158
 None
 1.02A 3wg7C-6dexB:
undetectable
3wg7J-6dexB:
undetectable		 3wg7C-6dexB:
undetectable
3wg7J-6dexB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 6dex SUPPRESSOR OF
HYDROXYUREA
SENSITIVITY PROTEIN
2
(Eremothecium
gossypii) 		5 / 12 PHE B 160
LEU B  22
VAL B  27
ALA B  42
SER B  44
 None
 1.34A 4a84A-6dexB:
undetectable		 4a84A-6dexB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FN9_B_STRB301_1
(STEROID RECEPTOR 2)		 6dex SUPPRESSOR OF
HYDROXYUREA
SENSITIVITY PROTEIN
2
(Eremothecium
gossypii) 		5 / 12 LEU B  11
LEU B  12
ALA B 161
TRP B  98
MET B 153
 None
 1.18A 4fn9B-6dexB:
undetectable		 4fn9B-6dexB:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LMN_A_EUIA503_1
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 6dex SUPPRESSOR OF
HYDROXYUREA
SENSITIVITY PROTEIN
1
(Eremothecium
gossypii) 		5 / 12 LEU A  78
LEU A  81
ILE A 125
GLY A 103
LEU A 108
 None
 0.87A 4lmnA-6dexA:
undetectable		 4lmnA-6dexA:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_C_3CJC607_1
(LACTOPEROXIDASE)		 6dex SUPPRESSOR OF
HYDROXYUREA
SENSITIVITY PROTEIN
1
SUPPRESSOR OF
HYDROXYUREA
SENSITIVITY PROTEIN
2
(Eremothecium
gossypii) 		4 / 6 ASP B  94
HIS B  97
ARG A 131
ARG B  78
 None
 1.41A 4qyqC-6dexB:
undetectable		 4qyqC-6dexB:
9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HPW_C_3CJC609_1
(LACTOPEROXIDASE)		 6dex SUPPRESSOR OF
HYDROXYUREA
SENSITIVITY PROTEIN
1
SUPPRESSOR OF
HYDROXYUREA
SENSITIVITY PROTEIN
2
(Eremothecium
gossypii) 		4 / 6 ASP B  94
HIS B  97
ARG A 131
ARG B  78
 None
 1.41A 5hpwC-6dexB:
undetectable		 5hpwC-6dexB:
9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC3_B_486B801_1
(GLUCOCORTICOID
RECEPTOR)		 6dex SUPPRESSOR OF
HYDROXYUREA
SENSITIVITY PROTEIN
2
(Eremothecium
gossypii) 		5 / 12 LEU B  12
ARG B 125
PHE B 136
MET B 153
LEU B  38
 None
 1.26A 5uc3B-6dexB:
undetectable		 5uc3B-6dexB:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 6dex SUPPRESSOR OF
HYDROXYUREA
SENSITIVITY PROTEIN
2
(Eremothecium
gossypii) 		4 / 6 ARG B  36
LEU B  38
PHE B  39
PHE B 158
 None
 0.97A 5x19P-6dexB:
undetectable		 5x19P-6dexB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 6dex SUPPRESSOR OF
HYDROXYUREA
SENSITIVITY PROTEIN
2
(Eremothecium
gossypii) 		4 / 5 ARG B  36
LEU B  38
PHE B  39
PHE B 158
 None
 1.01A 5x1bP-6dexB:
undetectable		 5x1bP-6dexB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 6dex SUPPRESSOR OF
HYDROXYUREA
SENSITIVITY PROTEIN
2
(Eremothecium
gossypii) 		4 / 7 ARG B  36
LEU B  38
PHE B  39
PHE B 158
 None
 0.95A 5x1fP-6dexB:
undetectable
5x1fW-6dexB:
undetectable		 5x1fP-6dexB:
undetectable
5x1fW-6dexB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKU_A_ZMRA901_2
(SIALIDASE)		 6dex SUPPRESSOR OF
HYDROXYUREA
SENSITIVITY PROTEIN
2
(Eremothecium
gossypii) 		4 / 6 ASP B 134
ASN B  14
LEU B  30
PHE B  34
 None
 1.16A 6ekuA-6dexB:
undetectable		 6ekuA-6dexB:
7.65