SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6df3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_A_DVAA6_0
(GRAMICIDIN A)		 6df3 -
(-) 		3 / 3 ALA L 209
VAL L 205
TRP L 208
 None
 0.92A 1bdwA-6df3L:
undetectable
1bdwB-6df3L:
undetectable		 1bdwA-6df3L:
undetectable
1bdwB-6df3L:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_A_IPHA802_0
(PHENOL HYDROXYLASE)		 6df3 -
(-) 		5 / 10 MET H  48
GLN H 162
VAL H 209
ARG H 133
ILE H 212
 None
 1.00A 1fohA-6df3H:
undetectable		 1fohA-6df3H:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_A_IPHA802_0
(PHENOL HYDROXYLASE)		 6df3

(;
) 		5 / 10 MET H  48
VAL H 209
ARG H 133
ILE H 212
GLY C  63
 None
 1.14A 1fohA-6df3H:
undetectable		 1fohA-6df3H:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_B_IPHB802_0
(PHENOL HYDROXYLASE)		 6df3 -
(-) 		5 / 10 MET H  48
GLN H 162
VAL H 209
ARG H 133
ILE H 212
 None
 1.02A 1fohB-6df3H:
undetectable		 1fohB-6df3H:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_B_IPHB802_0
(PHENOL HYDROXYLASE)		 6df3

(;
) 		5 / 10 MET H  48
VAL H 209
ARG H 133
ILE H 212
GLY C  63
 None
 1.13A 1fohB-6df3H:
undetectable		 1fohB-6df3H:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_C_IPHC802_0
(PHENOL HYDROXYLASE)		 6df3 -
(-) 		5 / 10 MET H  48
GLN H 162
VAL H 209
ARG H 133
ILE H 212
 None
 1.01A 1fohC-6df3H:
undetectable		 1fohC-6df3H:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_C_IPHC802_0
(PHENOL HYDROXYLASE)		 6df3

(;
) 		5 / 10 MET H  48
VAL H 209
ARG H 133
ILE H 212
GLY C  63
 None
 1.15A 1fohC-6df3H:
undetectable		 1fohC-6df3H:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_D_IPHD802_0
(PHENOL HYDROXYLASE)		 6df3 -
(-) 		5 / 10 MET H  48
GLN H 162
VAL H 209
ARG H 133
ILE H 212
 None
 1.01A 1fohD-6df3H:
undetectable		 1fohD-6df3H:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_A_DVAA6_0
(GRAMICIDIN C)		 6df3 -
(-) 		3 / 3 ALA C 166
VAL C  96
TRP C 199
 None
 0.94A 1jo4A-6df3C:
undetectable		 1jo4A-6df3C:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_B_DVAB6_0
(GRAMICIDIN C)		 6df3 -
(-) 		3 / 3 ALA C 166
VAL C  96
TRP C 199
 None
 0.94A 1jo4B-6df3C:
undetectable		 1jo4B-6df3C:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 6df3 -
(-) 		3 / 3 GLU L 168
HIS L 166
HIS L 178
 None
 0.71A 1oe2A-6df3L:
1.7		 1oe2A-6df3L:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_A_IPHA6012_0
(PHENOL
2-MONOOXYGENASE)		 6df3 -
(-) 		5 / 10 MET H  48
GLN H 162
VAL H 209
ARG H 133
ILE H 212
 None
 0.99A 1pn0A-6df3H:
undetectable		 1pn0A-6df3H:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_A_IPHA6012_0
(PHENOL
2-MONOOXYGENASE)		 6df3

(;
) 		5 / 10 MET H  48
VAL H 209
ARG H 133
ILE H 212
GLY C  63
 None
 1.15A 1pn0A-6df3H:
undetectable		 1pn0A-6df3H:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_B_IPHB6022_0
(PHENOL
2-MONOOXYGENASE)		 6df3 -
(-) 		5 / 10 MET H  48
GLN H 162
VAL H 209
ARG H 133
ILE H 212
 None
 1.00A 1pn0B-6df3H:
undetectable		 1pn0B-6df3H:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_B_IPHB6022_0
(PHENOL
2-MONOOXYGENASE)		 6df3

(;
) 		5 / 10 MET H  48
VAL H 209
ARG H 133
ILE H 212
GLY C  63
 None
 1.14A 1pn0B-6df3H:
undetectable		 1pn0B-6df3H:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_C_IPHC6032_0
(PHENOL
2-MONOOXYGENASE)		 6df3 -
(-) 		5 / 10 MET H  48
GLN H 162
VAL H 209
ARG H 133
ILE H 212
 None
 1.00A 1pn0C-6df3H:
undetectable		 1pn0C-6df3H:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_C_IPHC6032_0
(PHENOL
2-MONOOXYGENASE)		 6df3

(;
) 		5 / 10 MET H  48
VAL H 209
ARG H 133
ILE H 212
GLY C  63
 None
 1.17A 1pn0C-6df3H:
undetectable		 1pn0C-6df3H:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_D_IPHD6042_0
(PHENOL
2-MONOOXYGENASE)		 6df3 -
(-) 		5 / 10 MET H  48
GLN H 162
VAL H 209
ARG H 133
ILE H 212
 None
 1.00A 1pn0D-6df3H:
undetectable		 1pn0D-6df3H:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_D_IPHD6042_0
(PHENOL
2-MONOOXYGENASE)		 6df3

(;
) 		5 / 10 MET H  48
VAL H 209
ARG H 133
ILE H 212
GLY C  63
 None
 1.17A 1pn0D-6df3H:
undetectable		 1pn0D-6df3H:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KUH_A_HLTA150_1
(CALMODULIN)		 6df3 -
(-) 		4 / 6 LEU L 169
MET L 177
LEU L 179
GLU L 187
 None
 1.21A 2kuhA-6df3L:
undetectable		 2kuhA-6df3L:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6O_B_SAMB500_0
(HYPOTHETICAL PROTEIN)		 6df3 -
(-) 		4 / 6 VAL H 209
PHE H 165
PRO H 141
THR H 139
 None
 1.18A 2q6oB-6df3H:
undetectable		 2q6oB-6df3H:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_C_SAMC300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 6df3 -
(-) 		5 / 12 GLU H 206
ALA H 205
GLY H 142
LEU H 156
ALA H 168
 None
 1.17A 3ou6C-6df3H:
undetectable		 3ou6C-6df3H:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_C_FK5C204_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 6df3 -
(-) 		5 / 10 LEU C 197
ASP C 194
LEU C  92
LEU C 112
LEU C 140
 GOL  C 302 (-3.5A)
None
None
None
None
 0.97A 4odoC-6df3C:
undetectable		 4odoC-6df3C:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSN_A_MMZA503_1
(FLAVIN-CONTAINING
MONOOXYGENASE)		 6df3 -
(-) 		3 / 3 ASN H 110
SER H  76
SER H  80
 None
 0.77A 5gsnA-6df3H:
undetectable		 5gsnA-6df3H:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGJ_A_CTYA402_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 6df3 -
(-) 		4 / 5 HIS C 167
LEU C 151
TYR C 116
PHE C 115
 None
 1.22A 5igjA-6df3C:
undetectable		 5igjA-6df3C:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JM4_A_BEZA301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 6df3 -
(-) 		4 / 5 PHE C  54
ILE C 147
MET C 200
GLN C 201
 GOL  C 302 (-4.3A)
None
GOL  C 302 (-4.7A)
GOL  C 302 (-3.1A)
 1.34A 5jm4A-6df3C:
undetectable		 5jm4A-6df3C:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_D_ADND502_1
(ADENOSYLHOMOCYSTEINA
SE)		 6df3 -
(-) 		3 / 3 LEU L 156
ASN L  37
LEU L  88
 None
 0.71A 6exiD-6df3L:
undetectable		 6exiD-6df3L:
undetectable