SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6dft'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7F_A_BCZA801_1
(NEURAMINIDASE)		 6dft -
(-) 		3 / 3 ARG B  49
ARG B  91
ARG B  29
 None
 1.02A 1l7fA-6dftB:
undetectable		 1l7fA-6dftB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7H_A_BCZA801_1
(NEURAMINIDASE)		 6dft -
(-) 		3 / 3 ARG B  49
ARG B  91
ARG B  29
 None
 1.00A 1l7hA-6dftB:
undetectable		 1l7hA-6dftB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M4D_A_TOYA500_1
(AMINOGLYCOSIDE
2'-N-ACETYLTRANSFERA
SE)		 6dft -
(-) 		5 / 10 GLU B 103
SER B  72
ALA B  69
THR B  71
ASP B 213
 NAD  B 500 (-3.9A)
NAD  B 500 (-3.6A)
None
NAD  B 500 (-3.0A)
NAD  B 500 (-3.4A)
 1.31A 1m4dA-6dftB:
undetectable		 1m4dA-6dftB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y7I_A_SALA502_1
(SALICYLIC
ACID-BINDING PROTEIN
2)		 6dft -
(-) 		3 / 3 LEU B 303
HIS B 266
LYS B 265
 None
NAD  A 502 (-3.6A)
None
 0.89A 1y7iA-6dftB:
2.7		 1y7iA-6dftB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_A_SAMA4000_0
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 6dft

(;
) 		5 / 12 ILE B  75
GLY B 101
LEU B 263
ASP A 326
SER B 321
 None
None
NAD  A 502 (-3.7A)
NAD  A 502 (-3.6A)
None
 1.26A 1zq9A-6dftB:
2.4		 1zq9A-6dftB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_1
(CATECHOL-O-METHYLTRA
NSFERASE)		 6dft -
(-) 		3 / 3 SER A 220
GLU A 174
ASP A 205
 None
 0.69A 2avdB-6dftA:
undetectable		 2avdB-6dftA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_E_SAME301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 6dft

(;
) 		5 / 12 GLY A 373
ASP B 287
ASP A 405
ALA A 406
ALA A 398
 NAD  B 500 (-3.0A)
NAD  A 502 (-4.1A)
NAD  B 500 (-4.4A)
NAD  B 500 (-3.1A)
NAD  A 502 (-3.1A)
 1.15A 2br4E-6dftA:
2.5		 2br4E-6dftA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HW2_A_RFPA1200_1
(RIFAMPIN ADP-RIBOSYL
TRANSFERASE)		 6dft -
(-) 		5 / 12 ALA B  99
GLY B 214
THR B  97
GLY B 134
LEU B 136
 NAD  B 500 (-3.2A)
NAD  B 500 (-3.6A)
None
None
None
 1.07A 2hw2A-6dftB:
undetectable		 2hw2A-6dftB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 6dft -
(-) 		3 / 3 ARG A 240
THR A 339
VAL A 341
 None
 1.00A 2qakA-6dftA:
undetectable		 2qakA-6dftA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA801_1
(TRANSPORTER)		 6dft -
(-) 		5 / 12 LEU A 370
LEU A 101
ALA A 164
PHE A 102
LEU A 158
 None
NAD  A 502 (-4.6A)
None
None
None
 1.11A 2qb4A-6dftA:
undetectable		 2qb4A-6dftA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QJU_A_DSMA801_1
(TRANSPORTER)		 6dft -
(-) 		5 / 11 LEU A 370
LEU A 101
ALA A 164
PHE A 102
LEU A 158
 None
NAD  A 502 (-4.6A)
None
None
None
 1.14A 2qjuA-6dftA:
undetectable		 2qjuA-6dftA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX6_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 6dft -
(-) 		4 / 6 PHE B 150
ILE B 179
PHE B 146
GLY B 101
 None
 0.80A 2qx6A-6dftB:
2.7
2qx6B-6dftB:
3.4		 2qx6A-6dftB:
undetectable
2qx6B-6dftB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_D_ACTD37_0
(GCN4 LEUCINE ZIPPER)		 6dft

(;
) 		3 / 3 LYS B 228
ARG A 354
VAL A 349
 None
 1.05A 2r2vC-6dftB:
undetectable
2r2vD-6dftB:
undetectable		 2r2vC-6dftB:
undetectable
2r2vD-6dftB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_C_KLNC1498_1
(CYTOCHROME P450 3A4)		 6dft -
(-) 		5 / 12 LEU B 157
LEU B 154
ILE B 179
ALA B 182
ARG B 144
 None
 1.24A 2v0mC-6dftB:
undetectable		 2v0mC-6dftB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y05_A_RALA801_1
(PROSTAGLANDIN
REDUCTASE 1)		 6dft -
(-) 		4 / 8 VAL B 258
TYR B 279
VAL B 272
VAL B  96
 None
 1.20A 2y05A-6dftB:
4.5
2y05B-6dftB:
4.8		 2y05A-6dftB:
undetectable
2y05B-6dftB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB6_0
(FERROCHELATASE)		 6dft -
(-) 		5 / 12 LEU B  86
LEU B 325
ILE B 204
SER B 321
VAL B 280
 None
 1.32A 3aqiB-6dftB:
undetectable		 3aqiB-6dftB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWU_A_SREA801_1
(TRANSPORTER)		 6dft -
(-) 		5 / 12 LEU A 370
LEU A 101
ALA A 164
PHE A 102
LEU A 158
 None
NAD  A 502 (-4.6A)
None
None
None
 1.19A 3gwuA-6dftA:
undetectable		 3gwuA-6dftA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_B_ECNB602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 6dft -
(-) 		5 / 9 TYR B 143
GLY B 214
ALA B  99
THR B  97
ILE B  75
 None
NAD  B 500 (-3.6A)
NAD  B 500 (-3.2A)
None
None
 1.33A 3jusB-6dftB:
undetectable		 3jusB-6dftB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 6dft -
(-) 		3 / 3 ASN B 294
ASN B 301
GLU B 290
 None
NA  A 501 ( 4.8A)
None
 0.70A 3kpdC-6dftB:
undetectable		 3kpdC-6dftB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 6dft -
(-) 		3 / 3 ASN B 294
ASN B 301
GLU B 290
 None
NA  A 501 ( 4.8A)
None
 0.59A 3kpdB-6dftB:
undetectable		 3kpdB-6dftB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LD6_B_KKKB602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 6dft -
(-) 		5 / 12 TYR B 143
GLY B 214
ALA B  99
THR B  97
ILE B  75
 None
NAD  B 500 (-3.6A)
NAD  B 500 (-3.2A)
None
None
 1.36A 3ld6B-6dftB:
undetectable		 3ld6B-6dftB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_C_CGEC501_1
(CYTOCHROME P450 2B4)		 6dft -
(-) 		5 / 9 ILE B 179
PHE B 211
ALA B  99
THR B  97
VAL B 106
 None
None
NAD  B 500 (-3.2A)
None
None
 1.17A 3me6C-6dftB:
undetectable		 3me6C-6dftB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_D_CGED501_1
(CYTOCHROME P450 2B4)		 6dft -
(-) 		5 / 9 ILE B 179
PHE B 211
ALA B  99
THR B  97
VAL B 106
 None
None
NAD  B 500 (-3.2A)
None
None
 1.24A 3me6D-6dftB:
undetectable		 3me6D-6dftB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZV_B_ECNB411_1
(FLAVOHEMOGLOBIN)		 6dft -
(-) 		5 / 9 ILE A 263
GLN A 239
ALA A 236
LEU A 235
LEU A 324
 None
 1.02A 3ozvB-6dftA:
3.2		 3ozvB-6dftA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_A_9PLA501_1
(CYTOCHROME P450 2A6)		 6dft -
(-) 		5 / 10 PHE B 150
PHE B 146
ALA B  99
THR B  97
ILE B  75
 None
None
NAD  B 500 (-3.2A)
None
None
 1.00A 3t3qA-6dftB:
undetectable		 3t3qA-6dftB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_B_9PLB501_1
(CYTOCHROME P450 2A6)		 6dft -
(-) 		5 / 10 PHE B 150
PHE B 146
ALA B  99
THR B  97
ILE B  75
 None
None
NAD  B 500 (-3.2A)
None
None
 1.00A 3t3qB-6dftB:
undetectable		 3t3qB-6dftB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_C_9PLC501_1
(CYTOCHROME P450 2A6)		 6dft -
(-) 		5 / 10 PHE B 150
PHE B 146
ALA B  99
THR B  97
ILE B  75
 None
None
NAD  B 500 (-3.2A)
None
None
 1.00A 3t3qC-6dftB:
undetectable		 3t3qC-6dftB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_D_9PLD501_1
(CYTOCHROME P450 2A6)		 6dft -
(-) 		5 / 10 PHE B 150
PHE B 146
ALA B  99
THR B  97
ILE B  75
 None
None
NAD  B 500 (-3.2A)
None
None
 1.00A 3t3qD-6dftB:
undetectable		 3t3qD-6dftB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_B_SAMB401_0
(MNMC2)		 6dft -
(-) 		5 / 12 GLY B 260
GLY B 262
ALA B 317
ASN B  73
LEU B  74
 NAD  B 500 (-3.5A)
NAD  A 502 (-3.6A)
NAD  B 500 (-3.6A)
NAD  B 500 (-3.5A)
None
 1.25A 3vywB-6dftB:
2.3		 3vywB-6dftB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 6dft -
(-) 		5 / 12 LEU B  86
LEU B 325
ILE B 204
SER B 321
VAL B 280
 None
 1.29A 3w1wA-6dftB:
undetectable		 3w1wA-6dftB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1002_1
(HEMOLYTIC LECTIN
CEL-III)		 6dft -
(-) 		3 / 3 ASP A 402
GLU A 400
GLY A 407
 NAD  B 500 (-3.8A)
None
None
 0.53A 3w9tA-6dftA:
undetectable		 3w9tA-6dftA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E0F_A_RBFA301_1
(RIBOFLAVIN SYNTHASE
SUBUNIT ALPHA)		 6dft -
(-) 		5 / 11 SER B 291
VAL B 280
ALA B 317
HIS B 314
VAL B 313
 NAD  A 502 ( 3.1A)
None
NAD  B 500 (-3.6A)
None
None
 1.07A 4e0fA-6dftB:
undetectable		 4e0fA-6dftB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGJ_A_1PQA303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 6dft -
(-) 		5 / 9 GLY B 100
GLY B 101
PHE B 150
ILE B 179
PHE B 146
 NAD  B 500 (-3.5A)
None
None
None
None
 1.23A 4fgjA-6dftB:
3.3
4fgjB-6dftB:
3.4		 4fgjA-6dftB:
undetectable
4fgjB-6dftB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_C_MXMC606_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 6dft
() 		3 / 3 LEU B 125
ARG B 126
MET A 385
 None
 0.97A 4m11C-6dftB:
undetectable		 4m11C-6dftB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_2
(ADENOSINE KINASE)		 6dft -
(-) 		4 / 4 LEU B 183
SER B 185
LEU B 153
LEU B 110
 None
 1.10A 4n09A-6dftB:
3.2		 4n09A-6dftB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_C_STRC601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 6dft
() 		4 / 5 ILE A 329
ARG B 270
GLU A 166
VAL A 227
 None
 1.00A 4nkxC-6dftA:
undetectable		 4nkxC-6dftA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_D_STRD601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 6dft
() 		4 / 5 ILE A 329
ARG B 270
GLU A 166
VAL A 227
 None
 1.03A 4nkxD-6dftA:
undetectable		 4nkxD-6dftA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJB_A_198A1001_2
(ANDROGEN RECEPTOR)		 6dft -
(-) 		4 / 7 LEU A 370
LEU A 113
ILE A 319
VAL A 317
 None
 0.73A 4ojbA-6dftA:
undetectable		 4ojbA-6dftA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_B_SAMB301_1
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 6dft -
(-) 		4 / 5 TYR A 391
GLN A  68
SER A  69
ASP A 422
 None
 1.47A 4qtuB-6dftA:
undetectable		 4qtuB-6dftA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R82_A_ACTA207_0
(OXIDOREDUCTASE)		 6dft

(;
) 		4 / 4 GLU A 331
GLY A 327
HIS B 266
ARG B 270
 None
None
NAD  A 502 (-3.6A)
None
 1.49A 4r82A-6dftA:
undetectable
4r82B-6dftA:
undetectable		 4r82A-6dftA:
undetectable
4r82B-6dftA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 6dft -
(-) 		4 / 6 LEU A 438
ILE A 439
LEU A  54
TYR A  44
 None
 0.91A 4w5nA-6dftA:
undetectable		 4w5nA-6dftA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3M_A_ADNA301_1
(RNA 2'-O RIBOSE
METHYLTRANSFERASE)		 6dft -
(-) 		5 / 9 LEU A 370
GLY A 371
GLU A 431
ILE A 439
VAL A 432
 None
NAD  A 502 (-3.8A)
NAD  A 502 (-4.0A)
None
NAD  A 502 (-4.1A)
 1.50A 4x3mA-6dftA:
2.5		 4x3mA-6dftA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_A_ADNA303_1
(5'/3'-NUCLEOTIDASE
SURE)		 6dft -
(-) 		5 / 10 GLY B  46
ASN B  33
TYR B  35
ILE B 320
LEU B  45
 None
 1.11A 4xj7A-6dftB:
undetectable
4xj7B-6dftB:
undetectable		 4xj7A-6dftB:
undetectable
4xj7B-6dftB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_D_ADND303_1
(5'/3'-NUCLEOTIDASE
SURE)		 6dft -
(-) 		5 / 10 LEU B  45
GLY B  46
ASN B  33
TYR B  35
ILE B 320
 None
 1.10A 4xj7C-6dftB:
undetectable
4xj7D-6dftB:
undetectable		 4xj7C-6dftB:
undetectable
4xj7D-6dftB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJO_D_ERYD1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 6dft -
(-) 		5 / 11 TYR B  70
SER B 194
ALA B 181
THR B  97
GLY B 101
 None
 1.27A 4zjoD-6dftB:
undetectable		 4zjoD-6dftB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJO_D_ERYD1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 6dft -
(-) 		5 / 11 TYR B  70
SER B 194
ALA B 182
THR B  97
GLY B 101
 None
 1.40A 4zjoD-6dftB:
undetectable		 4zjoD-6dftB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EML_A_SAMA701_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 6dft -
(-) 		5 / 12 PRO B 152
LEU B 153
ASN B 145
ARG B  80
LEU B 183
 None
 1.24A 5emlA-6dftB:
2.6		 5emlA-6dftB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_D_QELD503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		 6dft -
(-) 		5 / 12 TYR B  70
ALA B  94
ILE B  92
PHE B  83
THR B 171
 None
 1.11A 5ewjC-6dftB:
undetectable
5ewjD-6dftB:
undetectable		 5ewjC-6dftB:
undetectable
5ewjD-6dftB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MM4_B_TA1B501_1
(TUBULIN BETA CHAIN)		 6dft -
(-) 		5 / 10 LEU B 268
SER B  77
PHE B  83
PRO B 322
LEU B 325
 None
 1.33A 5mm4B-6dftB:
3.9		 5mm4B-6dftB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 6dft -
(-) 		4 / 4 TYR A 391
ARG A 364
MET A  63
THR A  66
 None
 1.44A 5w97j-6dftA:
0.0		 5w97j-6dftA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1431_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 6dft
() 		4 / 7 ASN B 271
HIS B 267
ASP A 328
GLY A 163
 None
None
NAD  A 502 (-3.6A)
NAD  A 502 (-3.5A)
 1.02A 5x7pA-6dftB:
undetectable		 5x7pA-6dftB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZSF_A_6T0A910_0
(TOLL-LIKE RECEPTOR 7)		 6dft -
(-) 		4 / 7 THR A 104
LEU A 101
ILE A 110
PHE A 436
 None
NAD  A 502 (-4.6A)
None
None
 1.00A 5zsfA-6dftA:
1.4
5zsfB-6dftA:
undetectable		 5zsfA-6dftA:
undetectable
5zsfB-6dftA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CM4_A_8NUA2001_1
(D(2) DOPAMINE
RECEPTOR, ENDOLYSIN
CHIMERA)		 6dft

(;
) 		4 / 4 ASP B 316
ALA A 398
SER A 404
PHE B 118
 NAD  B 500 (-3.6A)
NAD  A 502 (-3.1A)
NAD  B 500 (-3.8A)
None
 1.38A 6cm4A-6dftB:
undetectable		 6cm4A-6dftB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ2_B_AB1B201_0
(HIV-1 PROTEASE)		 6dft -
(-) 		5 / 10 VAL A 440
GLY A  96
ILE A 369
VAL A 435
ILE A 439
 None
 1.02A 6dj2A-6dftA:
undetectable		 6dj2A-6dftA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		 6dft

(;
) 		4 / 7 ASP B 316
GLY B 134
PHE B 118
GLY A 403
 NAD  B 500 (-3.6A)
None
None
None
 0.86A 6ekzA-6dftB:
undetectable		 6ekzA-6dftB:
undetectable