SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6dgb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)
6dgb IS607 FAMILY
TRANSPOSASE IS1535

(Mycobacterium
tuberculosis)
5 / 11 ALA A 134
LEU A 135
LEU A 131
LEU A 123
ILE A 106
None
1.01A 1ha2A-6dgbA:
undetectable
1ha2A-6dgbA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_E_ACTE502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)
6dgb IS607 FAMILY
TRANSPOSASE IS1535

(Mycobacterium
tuberculosis)
3 / 3 LYS A  98
ARG A 168
LEU A  96
None
1.39A 3v4tE-6dgbA:
undetectable
3v4tE-6dgbA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_D_ACTD403_0
(D-ALANINE--D-ALANINE
LIGASE)
6dgb IS607 FAMILY
TRANSPOSASE IS1535

(Mycobacterium
tuberculosis)
4 / 6 TYR A  55
ARG A 100
GLY A  95
SER A  59
None
1.23A 5bphD-6dgbA:
5.4
5bphD-6dgbA:
undetectable